-
1
-
-
79959503826
-
The international hapmap project: The international hapmap consortium
-
DOI 10.1038/nature02168
-
International HapMap Consortium, The International HapMap Project. Nature 2003 426 6968 789 796 10.1038/nature02168 (Pubitemid 38056856)
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 789-796
-
-
-
2
-
-
79959524146
-
A haplotype map of the human genome
-
DOI 10.1038/nature04226, PII N04226
-
International HapMap Consortium, A haplotype map of the human genome. Nature 2005 437 7063 1299 1320 10.1038/nature04226 (Pubitemid 41568671)
-
(2005)
Nature
, vol.437
, Issue.7063
, pp. 1299-1320
-
-
-
3
-
-
18144425478
-
A genome-wide scalable SNP genotyping assay using microarray technology
-
DOI 10.1038/ng1547
-
Gunderson K. L., Steemers F. J., Lee G., Mendoza L. G., Chee M. S., A genome-wide scalable SNP genotyping assay using microarray technology. Nature Genetics 2005 37 5 549 554 2-s2.0-18144425478 10.1038/ng1547 (Pubitemid 40617286)
-
(2005)
Nature Genetics
, vol.37
, Issue.5
, pp. 549-554
-
-
Gunderson, K.L.1
Steemers, F.J.2
Lee, G.3
Mendoza, L.G.4
Chee, M.S.5
-
4
-
-
27144472560
-
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility
-
DOI 10.1038/ng1646, PII N1646
-
Reich D., Patterson N., De Jager P. L., McDonald G. J., Waliszewska A., Tandon A., Lincoln R. R., DeLoa C., Fruhan S. A., Cabre P., Bera O., Semana G., Kelly M. A., Francis D. A., Ardlie K., Khan O., Cree B. A. C., Hauser S. L., Oksenberg J. R., Hafler D. A., A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nature Genetics 2005 37 10 1113 1118 2-s2.0-27144472560 10.1038/ng1646 (Pubitemid 41486665)
-
(2005)
Nature Genetics
, vol.37
, Issue.10
, pp. 1113-1118
-
-
Reich, D.1
Patterson, N.2
De Jager, P.L.3
McDonald, G.J.4
Waliszewska, A.5
Tandon, A.6
Lincoln, R.R.7
DeLoa, C.8
Fruhan, S.A.9
Cabre, P.10
Bera, O.11
Semana, G.12
Kelly, M.A.13
Francis, D.A.14
Ardlie, K.15
Khan, O.16
Cree, B.A.C.17
Hauser, S.L.18
Oksenberg, J.R.19
Hafler, D.A.20
more..
-
5
-
-
31344476038
-
Whole-genome genotyping with the single-base extension assay
-
DOI 10.1038/nmeth842, PII N842
-
Steemers F. J., Chang W., Lee G., Barker D. L., Shen R., Gunderson K. L., Whole-genome genotyping with the single-base extension assay. Nature Methods 2006 3 1 31 33 2-s2.0-31344476038 10.1038/nmeth842 (Pubitemid 43135346)
-
(2006)
Nature Methods
, vol.3
, Issue.1
, pp. 31-33
-
-
Steemers, F.J.1
Chang, W.2
Lee, G.3
Barker, D.L.4
Shen, R.5
Gunderson, K.L.6
-
6
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
DOI 10.1038/nature06014, PII NATURE06014
-
Moffatt M. F., Kabesch M., Liang L., Dixon A. L., Strachan D., Heath S., Depner M., Von Berg A., Bufe A., Rietschel E., Heinzmann A., Simma B., Frischer T., Willis-Owen S. A. G., Wong K. C. C., Illig T., Vogelberg C., Weiland S. K., Von Mutius E., Abecasis G. R., Farrall M., Gut I. G., Lathrop G. M., Cookson W. O. C., Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007 448 7152 470 473 2-s2.0-34547216747 10.1038/nature06014 (Pubitemid 47123521)
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
Dixon, A.L.4
Strachan, D.5
Heath, S.6
Depner, M.7
Von Berg, A.8
Bufe, A.9
Rietschel, E.10
Heinzmann, A.11
Simma, B.12
Frischer, T.13
Willis-Owen, S.A.G.14
Wong, K.C.C.15
Illig, T.16
Vogelberg, C.17
Weiland, S.K.18
Von Mutius, E.19
Abecasis, G.R.20
Farrall, M.21
Gut, I.G.22
Lathrop, G.M.23
Cookson, W.O.C.24
more..
-
7
-
-
74049129976
-
Variants of DENND1B associated with asthma in children
-
10.1056/NEJMoa0901867
-
Sleiman P. M., Flory J., Imielinski M., Variants of DENND1B associated with asthma in children. The New England Journal of Medicine 2010 362 1 36 44 10.1056/NEJMoa0901867
-
(2010)
The New England Journal of Medicine
, vol.362
, Issue.1
, pp. 36-44
-
-
Sleiman, P.M.1
Flory, J.2
Imielinski, M.3
-
8
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
-
2-s2.0-70549084415 10.1038/ng.485
-
Satake W., Nakabayashi Y., Mizuta I., Hirota Y., Ito C., Kubo M., Kawaguchi T., Tsunoda T., Watanabe M., Takeda A., Tomiyama H., Nakashima K., Hasegawa K., Obata F., Yoshikawa T., Kawakami H., Sakoda S., Yamamoto M., Hattori N., Murata M., Nakamura Y., Toda T., Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nature Genetics 2009 41 12 1303 1307 2-s2.0-70549084415 10.1038/ng.485
-
(2009)
Nature Genetics
, vol.41
, Issue.12
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
Hirota, Y.4
Ito, C.5
Kubo, M.6
Kawaguchi, T.7
Tsunoda, T.8
Watanabe, M.9
Takeda, A.10
Tomiyama, H.11
Nakashima, K.12
Hasegawa, K.13
Obata, F.14
Yoshikawa, T.15
Kawakami, H.16
Sakoda, S.17
Yamamoto, M.18
Hattori, N.19
Murata, M.20
Nakamura, Y.21
Toda, T.22
more..
-
9
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
10.1038/ng.487
-
Simon-Sanchez J., Schulte C., Bras J. M., Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nature Genetics 2009 41 12 1308 1312 10.1038/ng.487
-
(2009)
Nature Genetics
, vol.41
, Issue.12
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
-
10
-
-
67349112868
-
Common genetic variants on 5p14.1 associate with autism spectrum disorders
-
10.1038/nature07999
-
Wang K., Zhang H., Ma D., Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature 2009 459 7246 528 533 10.1038/nature07999
-
(2009)
Nature
, vol.459
, Issue.7246
, pp. 528-533
-
-
Wang, K.1
Zhang, H.2
Ma, D.3
-
11
-
-
0033624575
-
The common PPAR γ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
-
2-s2.0-0033624575 10.1038/79216
-
Altshuler D., Hirschhorn J. N., Klannemark M., Lindgren C. M., Vohl M.-C., Nemesh J., Lane C. R., Schaffner S. F., Bolk S., Brewer C., Tuomi T., Gaudet D., Hudson T. J., Daly M., Groop L., Lander E. S., The common PPAR γ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nature Genetics 2000 26 1 76 80 2-s2.0-0033624575 10.1038/79216
-
(2000)
Nature Genetics
, vol.26
, Issue.1
, pp. 76-80
-
-
Altshuler, D.1
Hirschhorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.-C.5
Nemesh, J.6
Lane, C.R.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
Tuomi, T.11
Gaudet, D.12
Hudson, T.J.13
Daly, M.14
Groop, L.15
Lander, E.S.16
-
12
-
-
0037317981
-
ATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes
-
DOI 10.2337/diabetes.52.2.568
-
Gloyn A. L., Weedon M. N., Owen K. R., Turner M. J., Knight B. A., Hitman G., Walker M., Levy J. C., Sampson M., Halford S., McCarthy M. I., Hattersley A. T., Frayling T. M., Large-scale association studies of variants in genes encoding the pancreatic β -cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes. Diabetes 2003 52 2 568 572 2-s2.0-0037317981 10.2337/diabetes.52.2.568 (Pubitemid 36173218)
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 568-572
-
-
Gloyn, A.L.1
Weedon, M.N.2
Owen, K.R.3
Turner, M.J.4
Knight, B.A.5
Hitman, G.6
Walker, M.7
Levy, J.C.8
Sampson, M.9
Halford, S.10
McCarthy, M.I.11
Hattersley, A.T.12
Frayling, T.M.13
-
13
-
-
0033772073
-
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
-
10.1038/79876
-
Horikawa Y., Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genetics 2000 26 2 163 175 10.1038/79876
-
(2000)
Nature Genetics
, vol.26
, Issue.2
, pp. 163-175
-
-
Horikawa, Y.1
-
14
-
-
75749086085
-
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
-
10.1038/ng.520
-
Dupuis J., Langenberg C., Prokopenko I., New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nature Genetics 2010 42 2 105 116 10.1038/ng.520
-
(2010)
Nature Genetics
, vol.42
, Issue.2
, pp. 105-116
-
-
Dupuis, J.1
Langenberg, C.2
Prokopenko, I.3
-
15
-
-
34547510624
-
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes
-
DOI 10.1038/ng2062, PII NG2062
-
Gudmundsson J., Sulem P., Steinthorsdottir V., Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nature Genetics 2007 39 8 977 983 10.1038/ng2062 (Pubitemid 47185170)
-
(2007)
Nature Genetics
, vol.39
, Issue.8
, pp. 977-983
-
-
Gudmundsson, J.1
Sulem, P.2
Steinthorsdottir, V.3
Bergthorsson, J.T.4
Thorleifsson, G.5
Manolescu, A.6
Rafnar, T.7
Gudbjartsson, D.8
Agnarsson, B.A.9
Baker, A.10
Sigurdsson, A.11
Benediktsdottir, K.R.12
Jakobsdottir, M.13
Blondal, T.14
Stacey, S.N.15
Helgason, A.16
Gunnarsdottir, S.17
Olafsdottir, A.18
Kristinsson, K.T.19
Birgisdottir, B.20
Ghosh, S.21
Thorlacius, S.22
Magnusdottir, D.23
Stefansdottir, G.24
Kristjansson, K.25
Bagger, Y.26
Wilensky, R.L.27
Reilly, M.P.28
Morris, A.D.29
Kimber, C.H.30
Adeyemo, A.31
Chen, Y.32
Zhou, J.33
So, W.-Y.34
Tong, P.C.Y.35
Ng, M.C.Y.36
Hansen, T.37
Andersen, G.38
Borch-Johnsen, K.39
Jorgensen, T.40
Tres, A.41
Fuertes, F.42
Ruiz-Echarri, M.43
Asin, L.44
Saez, B.45
Van Boven, E.46
Klaver, S.47
Swinkels, D.W.48
Aben, K.K.49
Graif, T.50
Cashy, J.51
Suarez, B.K.52
Van Vierssen Trip, O.53
Frigge, M.L.54
Ober, C.55
Hofker, M.H.56
Wijmenga, C.57
Christiansen, C.58
Rader, D.J.59
Palmer, C.N.A.60
Rotimi, C.61
Chan, J.C.N.62
Pedersen, O.63
Sigurdsson, G.64
Benediktsson, R.65
Jonsson, E.66
Einarsson, G.V.67
Mayordomo, J.I.68
Catalona, W.J.69
Kiemeney, L.A.70
Barkardottir, R.B.71
Gulcher, J.R.72
Thorsteinsdottir, U.73
Kong, A.74
Stefansson, K.75
more..
-
16
-
-
70349557826
-
Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
-
2-s2.0-70349557826 10.1038/ng.443
-
Rung J., Cauchi S., Albrechtsen A., Shen L., Rocheleau G., Cavalcanti-Proença C., Bacot F., Balkau B., Belisle A., Borch-Johnsen K., Charpentier G., Dina C., Durand E., Elliott P., Hadjadj S., Järvelin M.-R., Laitinen J., Lauritzen T., Marre M., Mazur A., Meyre D., Montpetit A., Pisinger C., Posner B., Poulsen P., Pouta A., Prentki M., Ribel-Madsen R., Ruokonen A., Sandbaek A., Serre D., Tichet J., Vaxillaire M., Wojtaszewski J. F. P., Vaag A., Hansen T., Polychronakos C., Pedersen O., Froguel P., Sladek R., Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nature Genetics 2009 41 10 1110 1115 2-s2.0-70349557826 10.1038/ng.443
-
(2009)
Nature Genetics
, vol.41
, Issue.10
, pp. 1110-1115
-
-
Rung, J.1
Cauchi, S.2
Albrechtsen, A.3
Shen, L.4
Rocheleau, G.5
Cavalcanti-Proença, C.6
Bacot, F.7
Balkau, B.8
Belisle, A.9
Borch-Johnsen, K.10
Charpentier, G.11
Dina, C.12
Durand, E.13
Elliott, P.14
Hadjadj, S.15
Järvelin, M.-R.16
Laitinen, J.17
Lauritzen, T.18
Marre, M.19
Mazur, A.20
Meyre, D.21
Montpetit, A.22
Pisinger, C.23
Posner, B.24
Poulsen, P.25
Pouta, A.26
Prentki, M.27
Ribel-Madsen, R.28
Ruokonen, A.29
Sandbaek, A.30
Serre, D.31
Tichet, J.32
Vaxillaire, M.33
Wojtaszewski, J.F.P.34
Vaag, A.35
Hansen, T.36
Polychronakos, C.37
Pedersen, O.38
Froguel, P.39
Sladek, R.40
more..
-
17
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
DOI 10.1126/science.1142358
-
Saxena R., Voight B. F., Lyssenko V., Burtt N. P., De Bakker P. I. W., Chen H., Roix J. J., Kathiresan S., Hirschhorn J. N., Daly M. J., Hughes T. E., Groop L., Altshuler D., Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007 316 5829 1331 1336 2-s2.0-34249888775 10.1126/science.1142358 (Pubitemid 46871653)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
De Bakker, P.I.W.5
Chen, H.6
Roix, J.J.7
Kathiresan, S.8
Hirschhorn, J.N.9
Daly, M.J.10
Hughes, T.E.11
Groop, L.12
Altshuler, D.13
-
18
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in finns detects multiple susceptibility variants
-
DOI 10.1126/science.1142382
-
Scott L. J., Mohlke K. L., Bonnycastle L. L., Willer C. J., Li Y., Duren W. L., Erdos M. R., Stringham H. M., Chines P. S., Jackson A. U., Prokunina-Olsson L., Ding C.-J., Swift A. J., Narisu N., Hu T., Pruim R., Xiao R., Li X.-Y., Conneely K. N., Riebow N. L., Sprau A. G., Tong M., White P. P., Hetrick K. N., Barnhart M. W., Bark C. W., Goldstein J. L., Watkins L., Xiang F., Saramies J., Buchanan T. A., Watanabe R. M., Valle T. T., Kinnunen L., Abecasis G. R., Pugh E. W., Doheny K. F., Bergman R. N., Tuomilehto J., Collins F. S., Boehnke M., A genome-wide association study of type 2 diabetes in finns detects multiple susceptibility variants. Science 2007 316 5829 1341 1345 2-s2.0-34249885875 10.1126/science.1142382 (Pubitemid 46871655)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
Erdos, M.R.7
Stringham, H.M.8
Chines, P.S.9
Jackson, A.U.10
Prokunina-Olsson, L.11
Ding, C.-J.12
Swift, A.J.13
Narisu14
Hu, T.15
Pruim, R.16
Xiao, R.17
Li, X.-Y.18
Conneely, K.N.19
Riebow, N.L.20
Sprau, A.G.21
Tong, M.22
White, P.P.23
Hetrick, K.N.24
Barnhart, M.W.25
Bark, C.W.26
Goldstein, J.L.27
Watkins, L.28
Xiang, F.29
Saramies, J.30
Buchanan, T.A.31
Watanabe, R.M.32
Valle, T.T.33
Kinnunen, L.34
Abecasis, G.R.35
Pugh, E.W.36
Doheny, K.F.37
Bergman, R.N.38
Tuomilehto, J.39
Collins, F.S.40
Boehnke, M.41
more..
-
19
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
2-s2.0-33847176604 10.1038/nature05616
-
Sladek R., Rocheleau G., Rung J., Dina C., Shen L., Serre D., Boutin P., Vincent D., Belisle A., Hadjadj S., Balkau B., Heude B., Charpentier G., Hudson T. J., Montpetit A., Pshezhetsky A. V., Prentki M., Posner B. I., Balding D. J., Meyre D., Polychronakos C., Froguel P., A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007 445 7130 881 885 2-s2.0-33847176604 10.1038/nature05616
-
(2007)
Nature
, vol.445
, Issue.7130
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
Boutin, P.7
Vincent, D.8
Belisle, A.9
Hadjadj, S.10
Balkau, B.11
Heude, B.12
Charpentier, G.13
Hudson, T.J.14
Montpetit, A.15
Pshezhetsky, A.V.16
Prentki, M.17
Posner, B.I.18
Balding, D.J.19
Meyre, D.20
Polychronakos, C.21
Froguel, P.22
more..
-
20
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
DOI 10.1038/ng2043, PII NG2043
-
Steinthorsdottir V., Thorleifsson G., Reynisdottir I., Benediktsson R., Jonsdottir T., Walters G. B., Styrkarsdottir U., Gretarsdottir S., Emilsson V., Ghosh S., Baker A., Snorradottir S., Bjarnason H., Ng M. C. Y., Hansen T., Bagger Y., Wilensky R. L., Reilly M. P., Adeyemo A., Chen Y., Zhou J., Gudnason V., Chen G., Huang H., Lashley K., Doumatey A., So W.-Y., Ma R. C. Y., Andersen G., Borch-Johnsen K., Jorgensen T., Van Vliet-Ostaptchouk J. V., Hofker M. H., Wijmenga C., Christiansen C., Rader D. J., Rotimi C., Gurney M., Chan J. C. N., Pedersen O., Sigurdsson G., Gulcher J. R., Thorsteinsdottir U., Kong A., Stefansson K., A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nature Genetics 2007 39 6 770 775 2-s2.0-34249828965 10.1038/ng2043 (Pubitemid 46848592)
-
(2007)
Nature Genetics
, vol.39
, Issue.6
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
Walters, G.B.6
Styrkarsdottir, U.7
Gretarsdottir, S.8
Emilsson, V.9
Ghosh, S.10
Baker, A.11
Snorradottir, S.12
Bjarnason, H.13
Ng, M.C.Y.14
Hansen, T.15
Bagger, Y.16
Wilensky, R.L.17
Reilly, M.P.18
Adeyemo, A.19
Chen, Y.20
Zhou, J.21
Gudnason, V.22
Chen, G.23
Huang, H.24
Lashley, K.25
Doumatey, A.26
So, W.-Y.27
Ma, R.C.Y.28
Andersen, G.29
Borch-Johnsen, K.30
Jorgensen, T.31
Van Vliet-Ostaptchouk, J.V.32
Hofker, M.H.33
Wijmenga, C.34
Christiansen, C.35
Rader, D.J.36
Rotimi, C.37
Gurney, M.38
Chan, J.C.N.39
Pedersen, O.40
Sigurdsson, G.41
Gulcher, J.R.42
Thorsteinsdottir, U.43
Kong, A.44
Stefansson, K.45
more..
-
21
-
-
50449085212
-
SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations
-
2-s2.0-50449085212 10.1038/ng.208
-
Unoki H., Takahashi A., Kawaguchi T., Hara K., Horikoshi M., Andersen G., Ng D. P. K., Holmkvist J., Borch-Johnsen K., Jørgensen T., Sandbæk A., Lauritzen T., Hansen T., Nurbaya S., Tsunoda T., Kubo M., Babazono T., Hirose H., Hayashi M., Iwamoto Y., Kashiwagi A., Kaku K., Kawamori R., Tai E. S., Pedersen O., Kamatani N., Kadowaki T., Kikkawa R., Nakamura Y., Maeda S., SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. Nature Genetics 2008 40 9 1098 1102 2-s2.0-50449085212 10.1038/ng.208
-
(2008)
Nature Genetics
, vol.40
, Issue.9
, pp. 1098-1102
-
-
Unoki, H.1
Takahashi, A.2
Kawaguchi, T.3
Hara, K.4
Horikoshi, M.5
Andersen, G.6
Ng, D.P.K.7
Holmkvist, J.8
Borch-Johnsen, K.9
Jørgensen, T.10
Sandbæk, A.11
Lauritzen, T.12
Hansen, T.13
Nurbaya, S.14
Tsunoda, T.15
Kubo, M.16
Babazono, T.17
Hirose, H.18
Hayashi, M.19
Iwamoto, Y.20
Kashiwagi, A.21
Kaku, K.22
Kawamori, R.23
Tai, E.S.24
Pedersen, O.25
Kamatani, N.26
Kadowaki, T.27
Kikkawa, R.28
Nakamura, Y.29
Maeda, S.30
more..
-
22
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
10.1038/ng.609
-
Voight B. F., Scott L. J., Steinthorsdottir V., Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genetics 2010 42 7 579 589 10.1038/ng.609
-
(2010)
Nature Genetics
, vol.42
, Issue.7
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
-
23
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
DOI 10.1038/nature05911, PII NATURE05911
-
Burton P. R., Clayton D. G., Cardon L. R., Craddock N., Deloukas P., Duncanson A., Kwiatkowski D. P., McCarthy M. I., Ouwehand W. H., Samani N. J., Todd J. A., Donnelly P., Barrett J. C., Davison D., Easton D., Evans D., Leung H.-T., Marchini J. L., Morris A. P., Spencer C. C. A., Tobin M. D., Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007 447 7145 661 678 2-s2.0-34250025139 10.1038/nature05911 (Pubitemid 46889737)
-
(2007)
Nature
, vol.447
, Issue.7145
, pp. 661-678
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
Craddock, N.4
Deloukas, P.5
Duncanson, A.6
Kwiatkowski, D.P.7
McCarthy, M.I.8
Ouwehand, W.H.9
Samani, N.J.10
Todd, J.A.11
Donnelly, P.12
Barrett, J.C.13
Davison, D.14
Easton, D.15
Evans, D.16
Leung, H.-T.17
Marchini, J.L.18
Morris, A.P.19
Spencer, C.C.A.20
Tobin, M.D.21
more..
-
24
-
-
50449085998
-
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
-
10.1038/ng.207
-
Yasuda K., Miyake K., Horikawa Y., Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nature Genetics 2008 40 9 1092 1097 10.1038/ng.207
-
(2008)
Nature Genetics
, vol.40
, Issue.9
, pp. 1092-1097
-
-
Yasuda, K.1
Miyake, K.2
Horikawa, Y.3
-
25
-
-
42349106044
-
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
-
DOI 10.1038/ng.120, PII NG120
-
Zeggini E., Scott L. J., Saxena R., Voight B. F., Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics 2008 40 5 638 645 2-s2.0-42349106044 10.1038/ng.120 (Pubitemid 351601209)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 638-645
-
-
Zeggini, E.1
Scott, L.J.2
Saxena, R.3
Voight, B.F.4
-
26
-
-
34249895023
-
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
-
DOI 10.1126/science.1142364
-
Zeggini E., Weedon M. N., Lindgren C. M., Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science 2007 316 5829 1336 1341 10.1126/science.1142364 (Pubitemid 46871654)
-
(2007)
Science
, vol.316
, Issue.5829
, pp. 1336-1341
-
-
Zeggini, E.1
Weedon, M.N.2
Lindgren, C.M.3
Frayling, T.M.4
Elliott, K.S.5
Lango, H.6
Timpson, N.J.7
Perry, J.R.B.8
Rayner, N.W.9
Freathy, R.M.10
Barrett, J.C.11
Shields, B.12
Morris, A.P.13
Ellard, S.14
Groves, C.J.15
Harries, L.W.16
Marchini, J.L.17
Owen, K.R.18
Knight, B.19
Cardon, L.R.20
Walker, M.21
Hitman, G.A.22
Morris, A.D.23
Doney, A.S.F.24
McCarthy, M.I.25
Hattersley, A.T.26
Bruce, I.N.27
Donovan, H.28
Eyre, S.29
Gilbert, P.D.30
Hider, S.L.31
Hinks, A.M.32
John, S.L.33
Potter, C.34
Silman, A.J.35
Symmons, D.P.M.36
Thomson, W.37
Worthington, J.38
more..
-
27
-
-
58149175143
-
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk
-
2-s2.0-58149175143 10.1038/ng.277
-
Bouatia-Naji N., Bonnefond A., Cavalcanti-Proença C., Sparsø T., Holmkvist J., Marchand M., Delplanque J., Lobbens S., Rocheleau G., Durand E., De Graeve F., Chèvre J.-C., Borch-Johnsen K., Hartikainen A.-L., Ruokonen A., Tichet J., Marre M., Weill J., Heude B., Tauber M., Lemaire K., Schuit F., Elliott P., Jørgensen T., Charpentier G., Hadjadj S., Cauchi S., Vaxillaire M., Sladek R., Visvikis-Siest S., Balkau B., Lévy-Marchal C., Pattou F., Meyre D., Blakemore A. I. F., Jarvelin M.-R., Walley A. J., Hansen T., Dina C., Pedersen O., Froguel P., A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nature Genetics 2009 41 1 89 94 2-s2.0-58149175143 10.1038/ng.277
-
(2009)
Nature Genetics
, vol.41
, Issue.1
, pp. 89-94
-
-
Bouatia-Naji, N.1
Bonnefond, A.2
Cavalcanti-Proença, C.3
Sparsø, T.4
Holmkvist, J.5
Marchand, M.6
Delplanque, J.7
Lobbens, S.8
Rocheleau, G.9
Durand, E.10
De Graeve, F.11
Chèvre, J.-C.12
Borch-Johnsen, K.13
Hartikainen, A.-L.14
Ruokonen, A.15
Tichet, J.16
Marre, M.17
Weill, J.18
Heude, B.19
Tauber, M.20
Lemaire, K.21
Schuit, F.22
Elliott, P.23
Jørgensen, T.24
Charpentier, G.25
Hadjadj, S.26
Cauchi, S.27
Vaxillaire, M.28
Sladek, R.29
Visvikis-Siest, S.30
Balkau, B.31
Lévy-Marchal, C.32
Pattou, F.33
Meyre, D.34
Blakemore, A.I.F.35
Jarvelin, M.-R.36
Walley, A.J.37
Hansen, T.38
Dina, C.39
Pedersen, O.40
Froguel, P.41
more..
-
28
-
-
58149175669
-
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion
-
2-s2.0-58149175669 10.1038/ng.288
-
Lyssenko V., Nagorny C. L. F., Erdos M. R., Wierup N., Jonsson A., Spégel P., Bugliani M., Saxena R., Fex M., Pulizzi N., Isomaa B., Tuomi T., Nilsson P., Kuusisto J., Tuomilehto J., Boehnke M., Altshuler D., Sundler F., Eriksson J. G., Jackson A. U., Laakso M., Marchetti P., Watanabe R. M., Mulder H., Groop L., Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nature Genetics 2009 41 1 82 88 2-s2.0-58149175669 10.1038/ng.288
-
(2009)
Nature Genetics
, vol.41
, Issue.1
, pp. 82-88
-
-
Lyssenko, V.1
Nagorny, C.L.F.2
Erdos, M.R.3
Wierup, N.4
Jonsson, A.5
Spégel, P.6
Bugliani, M.7
Saxena, R.8
Fex, M.9
Pulizzi, N.10
Isomaa, B.11
Tuomi, T.12
Nilsson, P.13
Kuusisto, J.14
Tuomilehto, J.15
Boehnke, M.16
Altshuler, D.17
Sundler, F.18
Eriksson, J.G.19
Jackson, A.U.20
Laakso, M.21
Marchetti, P.22
Watanabe, R.M.23
Mulder, H.24
Groop, L.25
more..
-
29
-
-
58149156287
-
Variants in MTNR1B influence fasting glucose levels
-
10.1038/ng.290
-
Prokopenko I., Langenberg C., Florez J. C., Variants in MTNR1B influence fasting glucose levels. Nature Genetics 2009 41 1 77 81 10.1038/ng.290
-
(2009)
Nature Genetics
, vol.41
, Issue.1
, pp. 77-81
-
-
Prokopenko, I.1
Langenberg, C.2
Florez, J.C.3
-
30
-
-
34248594090
-
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
-
DOI 10.1126/science.1141634
-
Frayling T. M., Timpson N. J., Weedon M. N., Zeggini E., Freathy R. M., Lindgren C. M., Perry J. R. B., Elliott K. S., Lango H., Rayner N. W., Shields B., Harries L. W., Barrett J. C., Ellard S., Groves C. J., Knight B., Patch A.-M., Ness A. R., Ebrahim S., Lawlor D. A., Ring S. M., Ben-Shlomo Y., Jarvelin M.-R., Sovio U., Bennett A. J., Melzer D., Ferrucci L., Loos R. J. F., Barroso I., Wareham N. J., Karpe F., Owen K. R., Cardon L. R., Walker M., Hitman G. A., Palmer C. N. A., Doney A. S. F., Morris A. D., Smith G. D., Hattersley A. T., McCarthy M. I., A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007 316 5826 889 894 2-s2.0-34248594090 10.1126/science.1141634 (Pubitemid 46764279)
-
(2007)
Science
, vol.316
, Issue.5826
, pp. 889-894
-
-
Frayling, T.M.1
Timpson, N.J.2
Weedon, M.N.3
Zeggini, E.4
Freathy, R.M.5
Lindgren, C.M.6
Perry, J.R.B.7
Elliott, K.S.8
Lango, H.9
Rayner, N.W.10
Shields, B.11
Harries, L.W.12
Barrett, J.C.13
Ellard, S.14
Groves, C.J.15
Knight, B.16
Patch, A.-M.17
Ness, A.R.18
Ebrahim, S.19
Lawlor, D.A.20
Ring, S.M.21
Ben-Shlomo, Y.22
Jarvelin, M.-R.23
Sovio, U.24
Bennett, A.J.25
Melzer, D.26
Ferrucci, L.27
Loos, R.J.F.28
Barroso, I.29
Wareham, N.J.30
Karpe, F.31
Owen, K.R.32
Cardon, L.R.33
Walker, M.34
Hitman, G.A.35
Palmer, C.N.A.36
Doney, A.S.F.37
Morris, A.D.38
Smith, G.D.39
Hattersley, A.T.40
McCarthy, M.I.41
more..
-
31
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
2-s2.0-32544451924 10.1038/ng1732
-
Grant S. F. A., Thorleifsson G., Reynisdottir I., Benediktsson R., Manolescu A., Sainz J., Helgason A., Stefansson H., Emilsson V., Helgadottir A., Styrkarsdottir U., Magnusson K. P., Walters G. B., Palsdottir E., Jonsdottir T., Gudmundsdottir T., Gylfason A., Saemundsdottir J., Wilensky R. L., Reilly M. P., Rader D. J., Bagger Y., Christiansen C., Gudnason V., Sigurdsson G., Thorsteinsdottir U., Gulcher J. R., Kong A., Stefansson K., Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nature Genetics 2006 38 3 320 323 2-s2.0-32544451924 10.1038/ng1732
-
(2006)
Nature Genetics
, vol.38
, Issue.3
, pp. 320-323
-
-
Grant, S.F.A.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
Styrkarsdottir, U.11
Magnusson, K.P.12
Walters, G.B.13
Palsdottir, E.14
Jonsdottir, T.15
Gudmundsdottir, T.16
Gylfason, A.17
Saemundsdottir, J.18
Wilensky, R.L.19
Reilly, M.P.20
Rader, D.J.21
Bagger, Y.22
Christiansen, C.23
Gudnason, V.24
Sigurdsson, G.25
Thorsteinsdottir, U.26
Gulcher, J.R.27
Kong, A.28
Stefansson, K.29
more..
-
32
-
-
34447340935
-
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: A global meta-analysis
-
DOI 10.1007/s00109-007-0203-4
-
Cauchi S., El Achhab Y., Choquet H., Dina C., Krempler F., Weitgasser R., Nejjari C., Patsch W., Chikri M., Meyre D., Froguel P., TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis. Journal of Molecular Medicine 2007 85 7 777 782 2-s2.0-34447340935 10.1007/s00109-007-0203-4 (Pubitemid 47063530)
-
(2007)
Journal of Molecular Medicine
, vol.85
, Issue.7
, pp. 777-782
-
-
Cauchi, S.1
El Achhab, Y.2
Choquet, H.3
Dina, C.4
Krempler, F.5
Weitgasser, R.6
Nejjari, C.7
Patsch, W.8
Chikri, M.9
Meyre, D.10
Froguel, P.11
-
33
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
10.1038/nature09410
-
Lango Allen H., Estrada K., Lettre G., Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010 467 7317 832 838 10.1038/nature09410
-
(2010)
Nature
, vol.467
, Issue.7317
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
-
34
-
-
84655162045
-
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians
-
10.1038/ng.1019
-
Cho Y. S., Chen C. H., Hu C., Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in East Asians. Nature Genetics 2011 44 1 67 72 10.1038/ng.1019
-
(2011)
Nature Genetics
, vol.44
, Issue.1
, pp. 67-72
-
-
Cho, Y.S.1
Chen, C.H.2
Hu, C.3
-
35
-
-
80053385333
-
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci
-
2-s2.0-80053385333 10.1038/ng.921
-
Kooner J. S., Saleheen D., Sim X., Sehmi J., Zhang W., Frossard P., Been L. F., Chia K.-S., Dimas A. S., Hassanali N., Jafar T., Jowett J. B. M., Li X., Radha V., Rees S. D., Takeuchi F., Young R., Aung T., Basit A., Chidambaram M., Das D., Grundberg E., Hedman Å. K., Hydrie Z. I., Islam M., Khor C.-C., Kowlessur S., Kristensen M. M., Liju S., Lim W.-Y., Matthews D. R., Liu J., Morris A. P., Nica A. C., Pinidiyapathirage J. M., Prokopenko I., Rasheed A., Samuel M., Shah N., Shera A. S., Small K. S., Suo C., Wickremasinghe A. R., Wong T. Y., Yang M., Zhang F., Abecasis G. R., Barnett A. H., Deloukas P., Frayling T. M., Froguel P., Kato N., Katulanda P., Kelly M. A., Liang J., Mohan V., Sanghera D. K., Scott J., Seielstad M., Zimmet P. Z., Elliott P., Teo Y. Y., McCarthy M. I., Danesh J., Tai E. S., Chambers J. C., Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nature Genetics 2011 43 10 984 989 2-s2.0-80053385333 10.1038/ng.921
-
(2011)
Nature Genetics
, vol.43
, Issue.10
, pp. 984-989
-
-
Kooner, J.S.1
Saleheen, D.2
Sim, X.3
Sehmi, J.4
Zhang, W.5
Frossard, P.6
Been, L.F.7
Chia, K.-S.8
Dimas, A.S.9
Hassanali, N.10
Jafar, T.11
Jowett, J.B.M.12
Li, X.13
Radha, V.14
Rees, S.D.15
Takeuchi, F.16
Young, R.17
Aung, T.18
Basit, A.19
Chidambaram, M.20
Das, D.21
Grundberg, E.22
Hedman, Å.K.23
Hydrie, Z.I.24
Islam, M.25
Khor, C.-C.26
Kowlessur, S.27
Kristensen, M.M.28
Liju, S.29
Lim, W.-Y.30
Matthews, D.R.31
Liu, J.32
Morris, A.P.33
Nica, A.C.34
Pinidiyapathirage, J.M.35
Prokopenko, I.36
Rasheed, A.37
Samuel, M.38
Shah, N.39
Shera, A.S.40
Small, K.S.41
Suo, C.42
Wickremasinghe, A.R.43
Wong, T.Y.44
Yang, M.45
Zhang, F.46
Abecasis, G.R.47
Barnett, A.H.48
Deloukas, P.49
Frayling, T.M.50
Froguel, P.51
Kato, N.52
Katulanda, P.53
Kelly, M.A.54
Liang, J.55
Mohan, V.56
Sanghera, D.K.57
Scott, J.58
Seielstad, M.59
Zimmet, P.Z.60
Elliott, P.61
Teo, Y.Y.62
McCarthy, M.I.63
Danesh, J.64
Tai, E.S.65
Chambers, J.C.66
more..
-
36
-
-
84893716900
-
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
-
The SIGMA Type 2 Diabetes Consortium, 10.1038/nature12828
-
The SIGMA Type 2 Diabetes Consortium, Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature 2013 10.1038/nature12828
-
(2013)
Nature
-
-
-
37
-
-
77249134594
-
Rare variants create synthetic genome-wide associations
-
e1000294 2-s2.0-77249134594 10.1371/journal.pbio.1000294
-
Dickson S. P., Wang K., Krantz I., Hakonarson H., Goldstein D. B., Rare variants create synthetic genome-wide associations. PLoS Biology 2010 8 1 e1000294 2-s2.0-77249134594 10.1371/journal.pbio.1000294
-
(2010)
PLoS Biology
, vol.8
, Issue.1
-
-
Dickson, S.P.1
Wang, K.2
Krantz, I.3
Hakonarson, H.4
Goldstein, D.B.5
-
38
-
-
77951974619
-
Interpretation of association signals and identification of causal variants from genome-wide association studies
-
2-s2.0-77951974619 10.1016/j.ajhg.2010.04.003
-
Wang K., Dickson S. P., Stolle C. A., Krantz I. D., Goldstein D. B., Hakonarson H., Interpretation of association signals and identification of causal variants from genome-wide association studies. The American Journal of Human Genetics 2010 86 5 730 742 2-s2.0-77951974619 10.1016/j.ajhg.2010.04.003
-
(2010)
The American Journal of Human Genetics
, vol.86
, Issue.5
, pp. 730-742
-
-
Wang, K.1
Dickson, S.P.2
Stolle, C.A.3
Krantz, I.D.4
Goldstein, D.B.5
Hakonarson, H.6
-
39
-
-
77950405093
-
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
-
10.1038/nature08979
-
Craddock N., Hurles M. E., Cardin N., Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature 2010 464 7289 713 720 10.1038/nature08979
-
(2010)
Nature
, vol.464
, Issue.7289
, pp. 713-720
-
-
Craddock, N.1
Hurles, M.E.2
Cardin, N.3
-
40
-
-
0033594787
-
The fetal insulin hypothesis: An alternative explanation of the association of low birthweight with diabetes and vascular disease
-
DOI 10.1016/S0140-6736(98)07546-1
-
Hattersley A. T., Tooke J. E., The fetal insulin hypothesis: an alternative explanation of the association of low birthweight with diabetes and vascular disease. The Lancet 1999 353 9166 1789 1792 2-s2.0-0033594787 10.1016/S0140-6736(98)07546-1 (Pubitemid 29240389)
-
(1999)
Lancet
, vol.353
, Issue.9166
, pp. 1789-1792
-
-
Hattersley, A.T.1
Tooke, J.E.2
-
41
-
-
33745778040
-
Activating mutations in the gene encoding Kir6.2 alter fetal and postnatal growth and also cause neonatal diabetes
-
DOI 10.1210/jc.2006-0201
-
Slingerland A. S., Hattersley A. T., Activating mutations in the gene encoding Kir6.2 alter fetal and postnatal growth and also cause neonatal diabetes. Journal of Clinical Endocrinology and Metabolism 2006 91 7 2782 2788 2-s2.0-33745778040 10.1210/jc.2006-0201 (Pubitemid 44024651)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.7
, pp. 2782-2788
-
-
Slingerland, A.S.1
Hattersley, A.T.2
-
42
-
-
35448994352
-
Insulin gene mutations as a cause of permanent neonatal diabetes
-
DOI 10.1073/pnas.0707291104
-
Støy J., Edghill E. L., Flanagan S. E., Ye H., Paz V. P., Pluzhnikov A., Below J. E., Hayes M. G., Cox N. J., Lipkind G. M., Lipton R. B., Greeley S. A. W., Patch A.-M., Ellard S., Steiner D. F., Hattersley A. T., Philipson L. H., Bell G. I., Insulin gene mutations as a cause of permanent neonatal diabetes. Proceedings of the National Academy of Sciences of the United States of America 2007 104 38 15040 15044 2-s2.0-35448994352 10.1073/pnas.0707291104 (Pubitemid 47619589)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.38
, pp. 15040-15044
-
-
Stoy, J.1
Edghill, E.L.2
Flanagan, S.E.3
Ye, H.4
Paz, V.P.5
Pluzhnikov, A.6
Below, J.E.7
Hayes, M.G.8
Cox, N.J.9
Lipkind, G.M.10
Lipton, R.B.11
Greeley, S.A.W.12
Patch, A.-M.13
Ellard, S.14
Steiner, D.F.15
Hattersley, A.T.16
Philipson, L.H.17
Bell, G.I.18
-
43
-
-
77955558577
-
Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight
-
2-s2.0-77955558577 10.1007/s00125-010-1790-0
-
Andersson E. A., Pilgaard K., Pisinger C., Harder M. N., Grarup N., Færch K., Poulsen P., Witte D. R., Jørgensen T., Vaag A., Hansen T., Pedersen O., Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight. Diabetologia 2010 53 9 1908 1916 2-s2.0-77955558577 10.1007/s00125-010-1790-0
-
(2010)
Diabetologia
, vol.53
, Issue.9
, pp. 1908-1916
-
-
Andersson, E.A.1
Pilgaard, K.2
Pisinger, C.3
Harder, M.N.4
Grarup, N.5
Færch, K.6
Poulsen, P.7
Witte, D.R.8
Jørgensen, T.9
Vaag, A.10
Hansen, T.11
Pedersen, O.12
-
44
-
-
66649099906
-
Type 2 diabetes risk alleles are associated with reduced size at birth
-
2-s2.0-66649099906 10.2337/db08-1739
-
Freathy R. M., Bennett A. J., Ring S. M., Shields B., Groves C. J., Timpson N. J., Weedon M. N., Zeggini E., Lindgren C. M., Lango H., Perry J. R. B., Pouta A., Ruokonen A., Hyppönen E., Power C., Elliott P., Strachan D. P., Järvelin M.-R., Smith G. D., McCarthy M. I., Frayling T. M., Hattersley A. T., Type 2 diabetes risk alleles are associated with reduced size at birth. Diabetes 2009 58 6 1428 1433 2-s2.0-66649099906 10.2337/db08-1739
-
(2009)
Diabetes
, vol.58
, Issue.6
, pp. 1428-1433
-
-
Freathy, R.M.1
Bennett, A.J.2
Ring, S.M.3
Shields, B.4
Groves, C.J.5
Timpson, N.J.6
Weedon, M.N.7
Zeggini, E.8
Lindgren, C.M.9
Lango, H.10
Perry, J.R.B.11
Pouta, A.12
Ruokonen, A.13
Hyppönen, E.14
Power, C.15
Elliott, P.16
Strachan, D.P.17
Järvelin, M.-R.18
Smith, G.D.19
McCarthy, M.I.20
Frayling, T.M.21
Hattersley, A.T.22
more..
-
45
-
-
77951766379
-
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight
-
10.1038/ng.567
-
Freathy R. M., Mook-Kanamori D. O., Sovio U., Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight. Nature Genetics 2010 42 5 430 435 10.1038/ng.567
-
(2010)
Nature Genetics
, vol.42
, Issue.5
, pp. 430-435
-
-
Freathy, R.M.1
Mook-Kanamori, D.O.2
Sovio, U.3
-
46
-
-
64149117551
-
Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes
-
2-s2.0-64149117551 10.1007/s00125-009-1291-1
-
Pulizzi N., Lyssenko V., Jonsson A., Osmond C., Laakso M., Kajantie E., Barker D. J., Groop L. C., Eriksson J. G., Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes. Diabetologia 2009 52 5 825 829 2-s2.0-64149117551 10.1007/s00125-009-1291-1
-
(2009)
Diabetologia
, vol.52
, Issue.5
, pp. 825-829
-
-
Pulizzi, N.1
Lyssenko, V.2
Jonsson, A.3
Osmond, C.4
Laakso, M.5
Kajantie, E.6
Barker, D.J.7
Groop, L.C.8
Eriksson, J.G.9
-
47
-
-
70349642876
-
Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene
-
2-s2.0-70349642876 10.2337/db09-0506
-
Zhao J., Li M., Bradfield J. P., Wang K., Zhang H., Sleiman P., Kim C. E., Annaiah K., Glaberson W., Glessner J. T., Otieno F. G., Thomas K. A., Garris M., Hou C., Frackelton E. C., Chiavacci R. M., Berkowitz R. I., Hakonarson H., Grant S. F. A., Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene. Diabetes 2009 58 10 2414 2418 2-s2.0-70349642876 10.2337/db09-0506
-
(2009)
Diabetes
, vol.58
, Issue.10
, pp. 2414-2418
-
-
Zhao, J.1
Li, M.2
Bradfield, J.P.3
Wang, K.4
Zhang, H.5
Sleiman, P.6
Kim, C.E.7
Annaiah, K.8
Glaberson, W.9
Glessner, J.T.10
Otieno, F.G.11
Thomas, K.A.12
Garris, M.13
Hou, C.14
Frackelton, E.C.15
Chiavacci, R.M.16
Berkowitz, R.I.17
Hakonarson, H.18
Grant, S.F.A.19
-
48
-
-
77950357948
-
Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI
-
2-s2.0-77950357948 10.2337/db09-0972
-
Zhao J., Bradfield J. P., Zhang H., Annaiah K., Wang K., Kim C. E., Glessner J. T., Frackelton E. C., Otieno F. G., Doran J., Thomas K. A., Garris M., Hou C., Chiavacci R. M., Li M., Berkowitz R. I., Hakonarson H., Grant S. F. A., Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI. Diabetes 2010 59 3 751 755 2-s2.0-77950357948 10.2337/db09-0972
-
(2010)
Diabetes
, vol.59
, Issue.3
, pp. 751-755
-
-
Zhao, J.1
Bradfield, J.P.2
Zhang, H.3
Annaiah, K.4
Wang, K.5
Kim, C.E.6
Glessner, J.T.7
Frackelton, E.C.8
Otieno, F.G.9
Doran, J.10
Thomas, K.A.11
Garris, M.12
Hou, C.13
Chiavacci, R.M.14
Li, M.15
Berkowitz, R.I.16
Hakonarson, H.17
Grant, S.F.A.18
-
49
-
-
2342561802
-
Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet atp-sensitive potassium channel gene region
-
DOI 10.2337/diabetes.53.5.1360
-
Florez J. C., Burtt N., De Bakker P. I. W., Almgren P., Tuomi T., Holmkvist J., Gaudet D., Hudson T. J., Schaffner S. F., Daly M. J., Hirschhorn J. N., Groop L., Altshuler D., Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the Islet ATP-sensitive potassium channel gene region. Diabetes 2004 53 5 1360 1368 2-s2.0-2342561802 10.2337/diabetes.53.5.1360 (Pubitemid 38569024)
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1360-1368
-
-
Florez, J.C.1
Burtt, N.2
De Bakker, P.I.W.3
Almgren, P.4
Tuomi, T.5
Holmkvist, J.6
Gaudet, D.7
Hudson, T.J.8
Schaffner, S.F.9
Daly, M.J.10
Hirschhorn, J.N.11
Groop, L.12
Altshuler, D.13
-
50
-
-
56749101779
-
Genotype score in addition to common risk factors for prediction of type 2 diabetes
-
2-s2.0-56749101779 10.1056/NEJMoa0804742
-
Meigs J. B., Shrader P., Sullivan L. M., McAteer J. B., Fox C. S., Dupuis J., Manning A. K., Florez J. C., Wilson P. W. F., D'Agostino R. B. Sr., Cupples L. A., Genotype score in addition to common risk factors for prediction of type 2 diabetes. The New England Journal of Medicine 2008 359 21 2208 2219 2-s2.0-56749101779 10.1056/NEJMoa0804742
-
(2008)
The New England Journal of Medicine
, vol.359
, Issue.21
, pp. 2208-2219
-
-
Meigs, J.B.1
Shrader, P.2
Sullivan, L.M.3
McAteer, J.B.4
Fox, C.S.5
Dupuis, J.6
Manning, A.K.7
Florez, J.C.8
Wilson, P.W.F.9
D'Agostino Sr., R.B.10
Cupples, L.A.11
-
51
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
2-s2.0-55649105963 10.1056/NEJMoa0801869
-
Lyssenko V., Jonsson A., Almgren P., Pulizzi N., Isomaa B., Tuomi T., Berglund G., Altshuler D., Nilsson P., Groop L., Clinical risk factors, DNA variants, and the development of type 2 diabetes. The New England Journal of Medicine 2008 359 21 2220 2232 2-s2.0-55649105963 10.1056/NEJMoa0801869
-
(2008)
The New England Journal of Medicine
, vol.359
, Issue.21
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
Pulizzi, N.4
Isomaa, B.5
Tuomi, T.6
Berglund, G.7
Altshuler, D.8
Nilsson, P.9
Groop, L.10
-
52
-
-
79951715822
-
Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms
-
2-s2.0-79951715822 10.2337/dc10-1265
-
De Miguel-Yanes J. M., Shrader P., Pencina M. J., Fox C. S., Manning A. K., Grant R. W., Dupuis J., Florez J. C., D'Agostino R. B., Cupples L. A., Meigs J. B., Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care 2011 34 1 121 125 2-s2.0-79951715822 10.2337/dc10-1265
-
(2011)
Diabetes Care
, vol.34
, Issue.1
, pp. 121-125
-
-
De Miguel-Yanes, J.M.1
Shrader, P.2
Pencina, M.J.3
Fox, C.S.4
Manning, A.K.5
Grant, R.W.6
Dupuis, J.7
Florez, J.C.8
D'Agostino, R.B.9
Cupples, L.A.10
Meigs, J.B.11
-
53
-
-
79953216697
-
Updated genetic score based on 34 confirmed type 2 diabetes loci is associated with diabetes incidence and regression to normoglycemia in the Diabetes Prevention Program
-
2-s2.0-79953216697 10.2337/db10-1119
-
Hivert M.-F., Jablonski K. A., Perreault L., Saxena R., McAteer J. B., Franks P. W., Hamman R. F., Kahn S. E., Haffner S., Meigs J. B., Altshuler D., Knowler W. C., Florez J. C., Updated genetic score based on 34 confirmed type 2 diabetes loci is associated with diabetes incidence and regression to normoglycemia in the Diabetes Prevention Program. Diabetes 2011 60 4 1340 1348 2-s2.0-79953216697 10.2337/db10-1119
-
(2011)
Diabetes
, vol.60
, Issue.4
, pp. 1340-1348
-
-
Hivert, M.-F.1
Jablonski, K.A.2
Perreault, L.3
Saxena, R.4
McAteer, J.B.5
Franks, P.W.6
Hamman, R.F.7
Kahn, S.E.8
Haffner, S.9
Meigs, J.B.10
Altshuler, D.11
Knowler, W.C.12
Florez, J.C.13
-
54
-
-
84891500161
-
Genetic risk socre of 46 type 2 diabetes risk variants with changes in plasma glucose and estimates of pancreatic?-cell function over 5 years of follow-up
-
10.2337/db13-0362
-
Andersson E. A., Allin K. H., Sandholt C. H., Genetic risk socre of 46 type 2 diabetes risk variants with changes in plasma glucose and estimates of pancreatic?-cell function over 5 years of follow-up. Diabetes 2013 62 10 3610 3617 10.2337/db13-0362
-
(2013)
Diabetes
, vol.62
, Issue.10
, pp. 3610-3617
-
-
Andersson, E.A.1
Allin, K.H.2
Sandholt, C.H.3
-
55
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
10.1038/ng.2383
-
Morris A. P., Voight B. F., Teslovich T. M., Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nature Genetics 2012 44 9 981 990 10.1038/ng.2383
-
(2012)
Nature Genetics
, vol.44
, Issue.9
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
-
56
-
-
0033198994
-
Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability
-
Duval A., Gayet J., Zhou X.-P., Iacopetta B., Thomas G., Hamelin R., Frequent frameshift mutations of the TCF-4 gene in colorectal cancers with microsatellite instability. Cancer Research 1999 59 17 4213 4215 2-s2.0-0033198994 (Pubitemid 29418728)
-
(1999)
Cancer Research
, vol.59
, Issue.17
, pp. 4213-4215
-
-
Duval, A.1
Gayet, J.2
Zhou, X.-P.3
Iacopetta, B.4
Thomas, G.5
Hamelin, R.6
-
57
-
-
0034660872
-
The human T-cell transcription factor-4 gene: Structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines
-
Duval A., Rolland S., Tubacher E., Bui H., Thomas G., Hamelin R., The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines. Cancer Research 2000 60 14 3872 3879 2-s2.0-0034660872 (Pubitemid 32204580)
-
(2000)
Cancer Research
, vol.60
, Issue.14
, pp. 3872-3879
-
-
Duval, A.1
Rolland, S.2
Tubacher, E.3
Bui, H.4
Thomas, G.5
Hamelin, R.6
-
58
-
-
80053385552
-
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion
-
2-s2.0-80053385552 10.1038/ng.936
-
Bass A. J., Lawrence M. S., Brace L. E., Ramos A. H., Drier Y., Cibulskis K., Sougnez C., Voet D., Saksena G., Sivachenko A., Jing R., Parkin M., Pugh T., Verhaak R. G., Stransky N., Boutin A. T., Barretina J., Solit D. B., Vakiani E., Shao W., Mishina Y., Warmuth M., Jimenez J., Chiang D. Y., Signoretti S., Kaelin W. G. Jr., Spardy N., Hahn W. C., Hoshida Y., Ogino S., Depinho R. A., Chin L., Garraway L. A., Fuchs C. S., Baselga J., Tabernero J., Gabriel S., Lander E. S., Getz G., Meyerson M., Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nature Genetics 2011 43 10 964 970 2-s2.0-80053385552 10.1038/ng.936
-
(2011)
Nature Genetics
, vol.43
, Issue.10
, pp. 964-970
-
-
Bass, A.J.1
Lawrence, M.S.2
Brace, L.E.3
Ramos, A.H.4
Drier, Y.5
Cibulskis, K.6
Sougnez, C.7
Voet, D.8
Saksena, G.9
Sivachenko, A.10
Jing, R.11
Parkin, M.12
Pugh, T.13
Verhaak, R.G.14
Stransky, N.15
Boutin, A.T.16
Barretina, J.17
Solit, D.B.18
Vakiani, E.19
Shao, W.20
Mishina, Y.21
Warmuth, M.22
Jimenez, J.23
Chiang, D.Y.24
Signoretti, S.25
Kaelin Jr., W.G.26
Spardy, N.27
Hahn, W.C.28
Hoshida, Y.29
Ogino, S.30
Depinho, R.A.31
Chin, L.32
Garraway, L.A.33
Fuchs, C.S.34
Baselga, J.35
Tabernero, J.36
Gabriel, S.37
Lander, E.S.38
Getz, G.39
Meyerson, M.40
more..
-
59
-
-
51249110837
-
A genetic link between type 2 diabetes and prostate cancer
-
2-s2.0-51249110837 10.1007/s00125-008-1114-9
-
Frayling T. M., Colhoun H., Florez J. C., A genetic link between type 2 diabetes and prostate cancer. Diabetologia 2008 51 10 1757 1760 2-s2.0-51249110837 10.1007/s00125-008-1114-9
-
(2008)
Diabetologia
, vol.51
, Issue.10
, pp. 1757-1760
-
-
Frayling, T.M.1
Colhoun, H.2
Florez, J.C.3
-
60
-
-
39749118602
-
Multiple loci identified in a genome-wide association study of prostate cancer
-
DOI 10.1038/ng.91, PII NG91
-
Thomas G., Jacobs K. B., Yeager M., Multiple loci identified in a genome-wide association study of prostate cancer. Nature Genetics 2008 40 3 310 315 10.1038/ng.91 (Pubitemid 351311773)
-
(2008)
Nature Genetics
, vol.40
, Issue.3
, pp. 310-315
-
-
Thomas, G.1
Jacobs, K.B.2
Yeager, M.3
Kraft, P.4
Wacholder, S.5
Orr, N.6
Yu, K.7
Chatterjee, N.8
Welch, R.9
Hutchinson, A.10
Crenshaw, A.11
Cancel-Tassin, G.12
Staats, B.J.13
Wang, Z.14
Gonzalez-Bosquet, J.15
Fang, J.16
Deng, X.17
Berndt, S.I.18
Calle, E.E.19
Feigelson, H.S.20
Thun, M.J.21
Rodriguez, C.22
Albanes, D.23
Virtamo, J.24
Weinstein, S.25
Schumacher, F.R.26
Giovannucci, E.27
Willett, W.C.28
Cussenot, O.29
Valeri, A.30
Andriole, G.L.31
Crawford, E.D.32
Tucker, M.33
Gerhard, D.S.34
Fraumeni Jr., J.F.35
Hoover, R.36
Hayes, R.B.37
Hunter, D.J.38
Chanock, S.J.39
more..
-
61
-
-
20144389645
-
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function
-
DOI 10.1073/pnas.0409177102
-
Neve B., Fernandez-Zapico M. E., Ashkenazi-Katalan V., Dina C., Hamid Y. H., Joly E., Vaillant E., Benmezroua Y., Durand E., Bakaher N., Delannoy V., Vaxillaire M., Cook T., Dallinga-Thie G. M., Jansen H., Charles M.-A., Clément K., Galan P., Hercberg S., Helbecque N., Charpentier G., Prentki M., Hansen T., Pedersen O., Urrutia R., Melloul D., Froguel P., Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proceedings of the National Academy of Sciences of the United States of America 2005 102 13 4807 4812 2-s2.0-20144389645 10.1073/pnas.0409177102 (Pubitemid 40471535)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.13
, pp. 4807-4812
-
-
Neve, B.1
Fernandez-Zapico, M.E.2
Ashkenazi-Katalan, V.3
Dina, C.4
Hamid, Y.H.5
Joly, E.6
Vaillant, E.7
Benmezroua, Y.8
Durand, E.9
Bakaher, N.10
Delannoy, V.11
Vaxillaire, M.12
Cook, T.13
Dallinga-Thie, G.M.14
Jansen, H.15
Charles, M.-A.16
Clement, K.17
Galan, P.18
Hercberg, S.19
Helbecque, N.20
Charpentier, G.21
Prentki, M.22
Hansen, T.23
Pedersen, O.24
Urrutia, R.25
Melloul, D.26
Froguel, P.27
more..
-
62
-
-
34447132254
-
Brief report: PAX4 mutations in Thais with maturity onset diabetes of the young
-
DOI 10.1210/jc.2006-1927
-
Plengvidhya N., Kooptiwut S., Songtawee N., Doi A., Furuta H., Nishi M., Nanjo K., Tantibhedhyangkul W., Boonyasrisawat W., Yenchitsomanus P.-T., Doria A., Banchuin N., Brief report: PAX4 mutations in Thais with maturity onset diabetes of the young. Journal of Clinical Endocrinology and Metabolism 2007 92 7 2821 2826 2-s2.0-34447132254 10.1210/jc.2006-1927 (Pubitemid 47037395)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.7
, pp. 2821-2826
-
-
Plengvidhya, N.1
Kooptiwut, S.2
Songtawee, N.3
Doi, A.4
Furuta, H.5
Nishi, M.6
Nanjo, K.7
Tantibhedhyangkul, W.8
Boonyasrisawat, W.9
Yenchitsomanus, P.-T.10
Doria, A.11
Banchuin, N.12
-
63
-
-
70149104834
-
Mutations at the BLK locus linked to maturity onset diabetes of the young and β -cell dysfunction
-
2-s2.0-70149104834 10.1073/pnas.0906474106
-
Borowiec M., Liew C. W., Thompson R., Boonyasrisawat W., Hu J., Mlynarski W. M., El Khattabi I., Kim S.-H., Marselli L., Rich S. S., Krolewski A. S., Bonner-Weir S., Sharma A., Sale M., Mychaleckyj J. C., Kulkarni R. N., Doria A., Mutations at the BLK locus linked to maturity onset diabetes of the young and β -cell dysfunction. Proceedings of the National Academy of Sciences of the United States of America 2009 106 34 14460 14465 2-s2.0-70149104834 10.1073/pnas.0906474106
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.34
, pp. 14460-14465
-
-
Borowiec, M.1
Liew, C.W.2
Thompson, R.3
Boonyasrisawat, W.4
Hu, J.5
Mlynarski, W.M.6
El Khattabi, I.7
Kim, S.-H.8
Marselli, L.9
Rich, S.S.10
Krolewski, A.S.11
Bonner-Weir, S.12
Sharma, A.13
Sale, M.14
Mychaleckyj, J.C.15
Kulkarni, R.N.16
Doria, A.17
-
64
-
-
84858996746
-
Diagnosis and management of maturity onset diabetes of the young (MODY)
-
article d6044 10.1136/bmj.d6044 2-s2.0-80054844566
-
Thanabalasingham G., Owen K. R., Diagnosis and management of maturity onset diabetes of the young (MODY). British Medical Journal 2011 343, article d6044 10.1136/bmj.d6044 2-s2.0-80054844566
-
(2011)
British Medical Journal
, vol.343
-
-
Thanabalasingham, G.1
Owen, K.R.2
-
65
-
-
84877157032
-
Maturity onset diabetes of the young: Clinical characteristics, diagnosis and management
-
Kavvoura F. K., Owen K. R., Maturity onset diabetes of the young: clinical characteristics, diagnosis and management. Pediatric Endocrinology Reviews 2012 10 2 234 242
-
(2012)
Pediatric Endocrinology Reviews
, vol.10
, Issue.2
, pp. 234-242
-
-
Kavvoura, F.K.1
Owen, K.R.2
-
66
-
-
0032718689
-
Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus
-
Hani E. H., Stoffers D. A., Chèvre J.-C., Durand E., Stanojevic V., Dina C., Habener J. F., Froguel P., Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus. Journal of Clinical Investigation 1999 104 9 R41 R48 2-s2.0-0032718689 (Pubitemid 29536303)
-
(1999)
Journal of Clinical Investigation
, vol.104
, Issue.9
-
-
Hani, E.H.1
Stoffers, D.A.2
Chevre, J.-C.3
Durand, E.4
Stanojevic, V.5
Dina, C.6
Habener, J.F.7
Froguel, P.8
-
67
-
-
0032742985
-
Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes
-
Macfarlane W. M., Frayling T. M., Ellard S., Evans J. C., Allen L. I. S., Bulman M. P., Ayres S., Shepherd M., Clark P., Millward A., Demaine A., Wilkin T., Docherty K., Hattersley A. T., Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes. Journal of Clinical Investigation 1999 104 9 R33 R39 2-s2.0-0032742985 (Pubitemid 29536302)
-
(1999)
Journal of Clinical Investigation
, vol.104
, Issue.9
-
-
Macfarlane, W.M.1
Frayling, T.M.2
Ellard, S.3
Evans, J.C.4
Allen, L.I.S.5
Bulman, M.P.6
Ayres, S.7
Shepherd, M.8
Clark, P.9
Millward, A.10
Demaine, A.11
Wilkin, T.12
Docherty, K.13
Hattersley, A.T.14
-
68
-
-
0033027001
-
The hepatic nuclear factor-1α G319S variant is associated with early- onset type 2 diabetes in Canadian Oji-Cree
-
Hegele R. A., Cao H., Harris S. B., Hanley A. J. G., Zinman B., The hepatic nuclear factor-1 α G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree. Journal of Clinical Endocrinology and Metabolism 1999 84 3 1077 1082 2-s2.0-0033027001 (Pubitemid 29138246)
-
(1999)
Journal of Clinical Endocrinology and Metabolism
, vol.84
, Issue.3
, pp. 1077-1082
-
-
Hegele, R.A.1
Cao, H.2
Harris, S.B.3
Hanley, A.J.G.4
Zinman, B.5
-
69
-
-
67349199566
-
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
-
2-s2.0-67349199566 10.1038/ng.381
-
Barrett J. C., Clayton D. G., Concannon P., Akolkar B., Cooper J. D., Erlich H. A., Julier C., Morahan G., Nerup J., Nierras C., Plagnol V., Pociot F., Schuilenburg H., Smyth D. J., Stevens H., Todd J. A., Walker N. M., Rich S. S., Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nature Genetics 2009 41 6 703 707 2-s2.0-67349199566 10.1038/ng.381
-
(2009)
Nature Genetics
, vol.41
, Issue.6
, pp. 703-707
-
-
Barrett, J.C.1
Clayton, D.G.2
Concannon, P.3
Akolkar, B.4
Cooper, J.D.5
Erlich, H.A.6
Julier, C.7
Morahan, G.8
Nerup, J.9
Nierras, C.10
Plagnol, V.11
Pociot, F.12
Schuilenburg, H.13
Smyth, D.J.14
Stevens, H.15
Todd, J.A.16
Walker, N.M.17
Rich, S.S.18
-
70
-
-
80053439315
-
A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci
-
2-s2.0-80053439315 10.1371/journal.pgen.1002293 e1002293
-
Bradfield J. P., Qu H.-Q., Wang K., Zhang H., Sleiman P. M., Kim C. E., Mentch F. D., Qiu H., Glessner J. T., Thomas K. A., Frackelton E. C., Chiavacci R. M., Imielinski M., Monos D. S., Pandey R., Bakay M., Grant S. F. A., Polychronakos C., Hakonarson H., A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. PLoS Genetics 2011 7 9 2-s2.0-80053439315 10.1371/journal.pgen.1002293 e1002293
-
(2011)
PLoS Genetics
, vol.7
, Issue.9
-
-
Bradfield, J.P.1
Qu, H.-Q.2
Wang, K.3
Zhang, H.4
Sleiman, P.M.5
Kim, C.E.6
Mentch, F.D.7
Qiu, H.8
Glessner, J.T.9
Thomas, K.A.10
Frackelton, E.C.11
Chiavacci, R.M.12
Imielinski, M.13
Monos, D.S.14
Pandey, R.15
Bakay, M.16
Grant, S.F.A.17
Polychronakos, C.18
Hakonarson, H.19
-
71
-
-
56749183605
-
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
-
2-s2.0-56749183605 10.1038/ng.249
-
Cooper J. D., Smyth D. J., Smiles A. M., Plagnol V., Walker N. M., Allen J. E., Downes K., Barrett J. C., Healy B. C., Mychaleckyj J. C., Warram J. H., Todd J. A., Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nature Genetics 2008 40 12 1399 1401 2-s2.0-56749183605 10.1038/ng.249
-
(2008)
Nature Genetics
, vol.40
, Issue.12
, pp. 1399-1401
-
-
Cooper, J.D.1
Smyth, D.J.2
Smiles, A.M.3
Plagnol, V.4
Walker, N.M.5
Allen, J.E.6
Downes, K.7
Barrett, J.C.8
Healy, B.C.9
Mychaleckyj, J.C.10
Warram, J.H.11
Todd, J.A.12
-
72
-
-
46249094941
-
Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP
-
DOI 10.1371/journal.pone.0001746
-
Grant S. F. A., Li M., Bradfield J. P., Kim C. E., Annaiah K., Santa E., Glessner J. T., Casalunovo T., Frackelton E. C., Otieno F. G., Shaner J. L., Smith R. M., Imielinski M., Eckert A. W., Chiavacci R. M., Berkowitz R. I., Hakonarson H., Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. PLoS ONE 2008 3 3, article e1746 2-s2.0-46249094941 10.1371/journal.pone.0001746 (Pubitemid 351907760)
-
(2008)
PLoS ONE
, vol.3
, Issue.3
-
-
Grant, S.F.A.1
Li, M.2
Bradfield, J.P.3
Kim, C.E.4
Annaiah, K.5
Santa, E.6
Glessner, J.T.7
Casalunovo, T.8
Frackelton, E.C.9
Otieno, F.G.10
Shaner, J.L.11
Smith, R.M.12
Imielinski, M.13
Eckert, A.W.14
Chiavacci, R.M.15
Berkowitz, R.I.16
Hakonarson, H.17
-
73
-
-
34547621758
-
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
-
DOI 10.1038/nature06010, PII NATURE06010
-
Hakonarson H., Grant S. F. A., Bradfield J. P., Marchand L., Kim C. E., Glessner J. T., Grabs R., Casalunovo T., Taback S. P., Frackelton E. C., Lawson M. L., Robinson L. J., Skraban R., Lu Y., Chiavacci R. M., Stanley C. A., Kirsch S. E., Rappaport E. F., Orange J. S., Monos D. S., Devoto M., Qu H.-Q., Polychronakos C., A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature 2007 448 7153 591 594 2-s2.0-34547621758 10.1038/nature06010 (Pubitemid 47206935)
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 591-594
-
-
Hakonarson, H.1
Grant, S.F.A.2
Bradfield, J.P.3
Marchand, L.4
Kim, C.E.5
Glessner, J.T.6
Grabs, R.7
Casalunovo, T.8
Taback, S.P.9
Frackelton, E.C.10
Lawson, M.L.11
Robinson, L.J.12
Skraban, R.13
Lu, Y.14
Chiavacci, R.M.15
Stanley, C.A.16
Kirsch, S.E.17
Rappaport, E.F.18
Orange, J.S.19
Monos, D.S.20
Devoto, M.21
Qu, H.-Q.22
Polychronakos, C.23
more..
-
74
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
DOI 10.1038/ng2068, PII NG2068
-
Todd J. A., Walker N. M., Cooper J. D., Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nature Genetics 2007 39 7 857 864 10.1038/ng2068 (Pubitemid 47018195)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
Smyth, D.J.4
Downes, K.5
Plagnol, V.6
Bailey, R.7
Nejentsev, S.8
Field, S.F.9
Payne, F.10
Lowe, C.E.11
Szeszko, J.S.12
Hafler, J.P.13
Zeitels, L.14
Yang, J.H.M.15
Vella, A.16
Nutland, S.17
Stevens, H.E.18
Schuilenburg, H.19
Coleman, G.20
Maisuria, M.21
Meadows, W.22
Smink, L.J.23
Healy, B.24
Burren, O.S.25
Lam, A.A.C.26
Ovington, N.R.27
Allen, J.28
Adlem, E.29
Leung, H.-T.30
Wallace, C.31
Howson, J.M.M.32
Guja, C.33
Ionescu-Tirgoviste, C.34
Simmonds, M.J.35
Heward, J.M.36
Gough, S.C.L.37
Dunger, D.B.38
Wicker, L.S.39
Clayton, D.G.40
more..
-
75
-
-
77953643852
-
Can the genetics of type 1 and type 2 diabetes shed light on the genetics of latent autoimmune diabetes in adults?
-
2-s2.0-77953643852 10.1210/er.2009-0029
-
Grant S. F. A., Hakonarson H., Schwartz S., Can the genetics of type 1 and type 2 diabetes shed light on the genetics of latent autoimmune diabetes in adults? Endocrine Reviews 2010 31 2 183 193 2-s2.0-77953643852 10.1210/er.2009-0029
-
(2010)
Endocrine Reviews
, vol.31
, Issue.2
, pp. 183-193
-
-
Grant, S.F.A.1
Hakonarson, H.2
Schwartz, S.3
-
76
-
-
48249136253
-
Association analysis of type 2 diabetes loci in type 1 diabetes
-
2-s2.0-48249136253 10.2337/db08-0270
-
Qu H.-Q., Grant S. F. A., Bradfield J. P., Kim C., Frackelton E., Hakonarson H., Polychronakos C., Association analysis of type 2 diabetes loci in type 1 diabetes. Diabetes 2008 57 7 1983 1986 2-s2.0-48249136253 10.2337/db08-0270
-
(2008)
Diabetes
, vol.57
, Issue.7
, pp. 1983-1986
-
-
Qu, H.-Q.1
Grant, S.F.A.2
Bradfield, J.P.3
Kim, C.4
Frackelton, E.5
Hakonarson, H.6
Polychronakos, C.7
-
77
-
-
0026772731
-
Wnt genes
-
2-s2.0-0026772731 10.1016/0092-8674(92)90630-U
-
Nusse R., Varmus H. E., Wnt genes. Cell 1992 69 7 1073 1087 2-s2.0-0026772731 10.1016/0092-8674(92)90630-U
-
(1992)
Cell
, vol.69
, Issue.7
, pp. 1073-1087
-
-
Nusse, R.1
Varmus, H.E.2
-
78
-
-
49049103833
-
Wnt signaling and cancer development: Therapeutic implication
-
2-s2.0-49049103833
-
Paul S., Dey A., Wnt signaling and cancer development: therapeutic implication. Neoplasma 2008 55 3 165 176 2-s2.0-49049103833
-
(2008)
Neoplasma
, vol.55
, Issue.3
, pp. 165-176
-
-
Paul, S.1
Dey, A.2
-
80
-
-
0033119801
-
β-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
DOI 10.1038/18884
-
Tetsu O., McCormick F., β -catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999 398 6726 422 426 2-s2.0-0033119801 10.1038/18884 (Pubitemid 29180374)
-
(1999)
Nature
, vol.398
, Issue.6726
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
81
-
-
33846596193
-
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
-
DOI 10.1038/ng1960, PII NG1960
-
Helgason A., Pálsson S., Thorleifsson G., Grant S. F. A., Emilsson V., Gunnarsdottir S., Adeyemo A., Chen Y., Chen G., Reynisdottir I., Benediktsson R., Hinney A., Hansen T., Andersen G., Borch-Johnsen K., Jorgensen T., Schäfer H., Faruque M., Doumatey A., Zhou J., Wilensky R. L., Reilly M. P., Rader D. J., Bagger Y., Christiansen C., Sigurdsson G., Hebebrand J., Pedersen O., Thorsteinsdottir U., Gulcher J. R., Kong A., Rotimi C., Stefánsson K., Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nature Genetics 2007 39 2 218 225 2-s2.0-33846596193 10.1038/ng1960 (Pubitemid 46184353)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 218-225
-
-
Helgason, A.1
Palsson, S.2
Thorleifsson, G.3
Grant, S.F.A.4
Emilsson, V.5
Gunnarsdottir, S.6
Adeyemo, A.7
Chen, Y.8
Chen, G.9
Reynisdottir, I.10
Benediktsson, R.11
Hinney, A.12
Hansen, T.13
Andersen, G.14
Borch-Johnsen, K.15
Jorgensen, T.16
Schafer, H.17
Faruque, M.18
Doumatey, A.19
Zhou, J.20
Wilensky, R.L.21
Reilly, M.P.22
Rader, D.J.23
Bagger, Y.24
Christiansen, C.25
Sigurdsson, G.26
Hebebrand, J.27
Pedersen, O.28
Thorsteinsdottir, U.29
Gulcher, J.R.30
Kong, A.31
Rotimi, C.32
Stefansson, K.33
more..
-
82
-
-
79551609852
-
Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant
-
2-s2.0-79551609852 10.2337/db10-0134
-
Palmer N. D., Hester J. M., An S. S., Adeyemo A., Rotimi C., Langefeld C. D., Freedman B. I., Ng M. C. Y., Bowden D. W., Resequencing and analysis of variation in the TCF7L2 gene in African Americans suggests that SNP rs7903146 is the causal diabetes susceptibility variant. Diabetes 2011 60 2 662 668 2-s2.0-79551609852 10.2337/db10-0134
-
(2011)
Diabetes
, vol.60
, Issue.2
, pp. 662-668
-
-
Palmer, N.D.1
Hester, J.M.2
An, S.S.3
Adeyemo, A.4
Rotimi, C.5
Langefeld, C.D.6
Freedman, B.I.7
Ng, M.C.Y.8
Bowden, D.W.9
-
83
-
-
84870502629
-
Bayesian refinement of association signals for 14 loci in 3 common diseases
-
10.1038/ng.2435
-
Maller J. B., McVean G., Byrnes J., Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genetics 2012 44 12 1294 1301 10.1038/ng.2435
-
(2012)
Nature Genetics
, vol.44
, Issue.12
, pp. 1294-1301
-
-
Maller, J.B.1
McVean, G.2
Byrnes, J.3
-
84
-
-
34948845069
-
Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population
-
DOI 10.2337/db07-0421
-
Chang Y.-C., Chang T.-J., Jiang Y.-D., Kuo S.-S., Lee K.-C., Chiu K. C., Chuang L.-M., Association study of the genetic polymorphisms of the transcription factor 7-like 2 (TCF7L2) gene and type 2 diabetes in the Chinese population. Diabetes 2007 56 10 2631 2637 2-s2.0-34948845069 10.2337/db07-0421 (Pubitemid 47523272)
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2631-2637
-
-
Chang, Y.-C.1
Chang, T.-J.2
Jiang, Y.-D.3
Kuo, S.-S.4
Lee, K.-C.5
Chiu, K.C.6
Chuang, L.-M.7
-
85
-
-
50449104632
-
Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians
-
2-s2.0-50449104632 10.2337/db07-1583
-
Ng M. C. Y., Park K. S., Oh B., Tam C. H. T., Cho Y. M., Shin H. D., Lam V. K. L., Ma R. C. W., So W. Y., Cho Y. S., Kim H.-L., Lee H. K., Chan J. C. N., Cho N. H., Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians. Diabetes 2008 57 8 2226 2233 2-s2.0-50449104632 10.2337/db07-1583
-
(2008)
Diabetes
, vol.57
, Issue.8
, pp. 2226-2233
-
-
Ng, M.C.Y.1
Park, K.S.2
Oh, B.3
Tam, C.H.T.4
Cho, Y.M.5
Shin, H.D.6
Lam, V.K.L.7
Ma, R.C.W.8
So, W.Y.9
Cho, Y.S.10
Kim, H.-L.11
Lee, H.K.12
Chan, J.C.N.13
Cho, N.H.14
-
86
-
-
34548765645
-
Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese
-
DOI 10.1210/jc.2007-0849
-
Ng M. C. Y., Tam C. H. T., Lam V. K. L., So W.-Y., Ma R. C. W., Chan J. C. N., Replication and identification of novel variants at TCF7L2 associated with type 2 diabetes in Hong Kong Chinese. Journal of Clinical Endocrinology and Metabolism 2007 92 9 3733 3737 2-s2.0-34548765645 10.1210/jc.2007-0849 (Pubitemid 47435363)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.9
, pp. 3733-3737
-
-
Ng, M.C.Y.1
Tam, C.H.T.2
Lam, V.K.L.3
So, W.-Y.4
Ma, R.C.W.5
Chan, J.C.N.6
-
87
-
-
44749093346
-
Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population
-
2-s2.0-44749093346 10.1007/s00125-008-1039-3
-
Ren Q., Han X. Y., Wang F., Zhang X. Y., Han L. C., Luo Y. Y., Zhou X. H., Ji L. N., Exon sequencing and association analysis of polymorphisms in TCF7L2 with type 2 diabetes in a Chinese population. Diabetologia 2008 51 7 1146 1152 2-s2.0-44749093346 10.1007/s00125-008-1039-3
-
(2008)
Diabetologia
, vol.51
, Issue.7
, pp. 1146-1152
-
-
Ren, Q.1
Han, X.Y.2
Wang, F.3
Zhang, X.Y.4
Han, L.C.5
Luo, Y.Y.6
Zhou, X.H.7
Ji, L.N.8
-
88
-
-
77149143848
-
KCNJ11 Lys23Glu and TCF7L2 rs290487(C/T) polymorphisms affect therapeutic efficacy of repaglinide in Chinese patients with type 2 diabetes
-
2-s2.0-77149143848 10.1038/clpt.2009.242
-
Yu M., Xu X.-J., Yin J.-Y., Wu J., Chen X., Gong Z.-C., Ren H.-Y., Huang Q., Sheng F.-F., Zhou H.-H., Liu Z.-Q., KCNJ11 Lys23Glu and TCF7L2 rs290487(C/T) polymorphisms affect therapeutic efficacy of repaglinide in Chinese patients with type 2 diabetes. Clinical Pharmacology and Therapeutics 2010 87 3 330 335 2-s2.0-77149143848 10.1038/clpt.2009.242
-
(2010)
Clinical Pharmacology and Therapeutics
, vol.87
, Issue.3
, pp. 330-335
-
-
Yu, M.1
Xu, X.-J.2
Yin, J.-Y.3
Wu, J.4
Chen, X.5
Gong, Z.-C.6
Ren, H.-Y.7
Huang, Q.8
Sheng, F.-F.9
Zhou, H.-H.10
Liu, Z.-Q.11
-
89
-
-
84855186825
-
Association of type 2 diabetes susceptibility genes (TCF7L2, SLC30A8, PCSK1 and PCSK2) and proinsulin conversion in a Chinese population
-
2-s2.0-84855186825 10.1007/s11033-011-0705-6
-
Zheng X., Ren W., Zhang S., Liu J., Li S., Li J., Yang P., He J., Su S., Li P., Association of type 2 diabetes susceptibility genes (TCF7L2, SLC30A8, PCSK1 and PCSK2) and proinsulin conversion in a Chinese population. Molecular Biology Reports 2012 39 1 17 23 2-s2.0-84855186825 10.1007/s11033-011-0705-6
-
(2012)
Molecular Biology Reports
, vol.39
, Issue.1
, pp. 17-23
-
-
Zheng, X.1
Ren, W.2
Zhang, S.3
Liu, J.4
Li, S.5
Li, J.6
Yang, P.7
He, J.8
Su, S.9
Li, P.10
-
90
-
-
77649086970
-
A map of open chromatin in human pancreatic islets
-
2-s2.0-77649086970 10.1038/ng.530
-
Gaulton K. J., Nammo T., Pasquali L., Simon J. M., Giresi P. G., Fogarty M. P., Panhuis T. M., Mieczkowski P., Secchi A., Bosco D., Berney T., Montanya E., Mohlke K. L., Lieb J. D., Ferrer J., A map of open chromatin in human pancreatic islets. Nature Genetics 2010 42 3 255 259 2-s2.0-77649086970 10.1038/ng.530
-
(2010)
Nature Genetics
, vol.42
, Issue.3
, pp. 255-259
-
-
Gaulton, K.J.1
Nammo, T.2
Pasquali, L.3
Simon, J.M.4
Giresi, P.G.5
Fogarty, M.P.6
Panhuis, T.M.7
Mieczkowski, P.8
Secchi, A.9
Bosco, D.10
Berney, T.11
Montanya, E.12
Mohlke, K.L.13
Lieb, J.D.14
Ferrer, J.15
-
91
-
-
44849083863
-
TCF7L2 genetic defect and type 2 diabetes
-
2-s2.0-44849083863 10.1007/s11892-008-0026-x
-
Cauchi S., Froguel P., TCF7L2 genetic defect and type 2 diabetes. Current Diabetes Reports 2008 8 2 149 155 2-s2.0-44849083863 10.1007/s11892-008-0026-x
-
(2008)
Current Diabetes Reports
, vol.8
, Issue.2
, pp. 149-155
-
-
Cauchi, S.1
Froguel, P.2
-
92
-
-
34547702501
-
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
-
DOI 10.1172/JCI30706
-
Lyssenko V., Lupi R., Marchetti P., Del Guerra S., Orho-Melander M., Almgren P., Sjögren M., Ling C., Eriksson K.-F., Lethagen Å.-L., Mancarella R., Berglund G., Tuomi T., Nilsson P., Del Prato S., Groop L., Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. Journal of Clinical Investigation 2007 117 8 2155 2163 2-s2.0-34547702501 10.1172/JCI30706 (Pubitemid 47219560)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2155-2163
-
-
Lyssenko, V.1
Lupi, R.2
Marchetti, P.3
Del Guerra, S.4
Orho-Melander, M.5
Almgren, P.6
Sjogren, M.7
Ling, C.8
Eriksson, K.-F.9
Lethagen, A.-L.10
Mancarella, R.11
Berglund, G.12
Tuomi, T.13
Nilsson, P.14
Del Prato, S.15
Groop, L.16
-
93
-
-
34447131039
-
Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent
-
DOI 10.1007/s00125-007-0717-x
-
Elbein S. C., Chu W. S., Das S. K., Yao-Borengasser A., Hasstedt S. J., Wang H., Rasouli N., Kern P. A., Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia 2007 50 8 1621 1630 2-s2.0-34447131039 10.1007/s00125-007-0717-x (Pubitemid 47036661)
-
(2007)
Diabetologia
, vol.50
, Issue.8
, pp. 1621-1630
-
-
Elbein, S.C.1
Chu, W.S.2
Das, S.K.3
Yao-Borengasser, A.4
Hasstedt, S.J.5
Wang, H.6
Rasouli, N.7
Kern, P.A.8
-
94
-
-
77958468040
-
Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes
-
2-s2.0-77958468040 10.1007/s11892-010-0149-8
-
Hansson O., Zhou Y., Renström E., Osmark P., Molecular function of TCF7L2: Consequences of TCF7L2 splicing for molecular function and risk for type 2 diabetes. Current Diabetes Reports 2010 10 6 444 451 2-s2.0-77958468040 10.1007/s11892-010-0149-8
-
(2010)
Current Diabetes Reports
, vol.10
, Issue.6
, pp. 444-451
-
-
Hansson, O.1
Zhou, Y.2
Renström, E.3
Osmark, P.4
-
95
-
-
64149124055
-
Unique splicing pattern of the TCF7L2 gene in human pancreatic islets
-
2-s2.0-64149124055 10.1007/s00125-009-1293-z
-
Osmark P., Hansson O., Jonsson A., Rönn T., Groop L., Renström E., Unique splicing pattern of the TCF7L2 gene in human pancreatic islets. Diabetologia 2009 52 5 850 854 2-s2.0-64149124055 10.1007/s00125-009-1293-z
-
(2009)
Diabetologia
, vol.52
, Issue.5
, pp. 850-854
-
-
Osmark, P.1
Hansson, O.2
Jonsson, A.3
Rönn, T.4
Groop, L.5
Renström, E.6
-
96
-
-
84866072918
-
TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals
-
10.1007/s00125-012-2660-8
-
Le Bacquer O., Kerr-Conte J., Gargani S., TCF7L2 rs7903146 impairs islet function and morphology in non-diabetic individuals. Diabetologia 2012 55 10 2677 2681 10.1007/s00125-012-2660-8
-
(2012)
Diabetologia
, vol.55
, Issue.10
, pp. 2677-2681
-
-
Le Bacquer, O.1
Kerr-Conte, J.2
Gargani, S.3
-
97
-
-
40949141938
-
Transcription factor 7-like 2 regulates β -cell survival and function in human pancreatic islets
-
2-s2.0-40949141938 10.2337/db07-0847
-
Shu L., Sauter N. S., Schulthess F. T., Matveyenko A. V., Oberholzer J., Maedler K., Transcription factor 7-like 2 regulates β -cell survival and function in human pancreatic islets. Diabetes 2008 57 3 645 653 2-s2.0-40949141938 10.2337/db07-0847
-
(2008)
Diabetes
, vol.57
, Issue.3
, pp. 645-653
-
-
Shu, L.1
Sauter, N.S.2
Schulthess, F.T.3
Matveyenko, A.V.4
Oberholzer, J.5
Maedler, K.6
-
98
-
-
43749120731
-
Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation
-
2-s2.0-43749120731 10.1074/jbc.M706105200
-
Liu Z., Habener J. F., Glucagon-like peptide-1 activation of TCF7L2-dependent Wnt signaling enhances pancreatic beta cell proliferation. Journal of Biological Chemistry 2008 283 13 8723 8735 2-s2.0-43749120731 10.1074/jbc.M706105200
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.13
, pp. 8723-8735
-
-
Liu, Z.1
Habener, J.F.2
-
99
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
DOI 10.1038/1270
-
Korinek V., Barker N., Moerer P., Van Donselaar E., Huls G., Peters P. J., Clevers H., Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nature Genetics 1998 19 4 379 383 2-s2.0-0031848068 10.1038/1270 (Pubitemid 28357912)
-
(1998)
Nature Genetics
, vol.19
, Issue.4
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
Van Donselaar, E.4
Huls, G.5
Peters, P.J.6
Clevers, H.7
-
100
-
-
12544254474
-
TCF-4 mediates cell type-specific regulation of proglucagon gene expression by β -catenin and glycogen synthase kinase-3 β
-
2-s2.0-12544254474 10.1074/jbc.M411487200
-
Yi F., Brubaker P. L., Jin T., TCF-4 mediates cell type-specific regulation of proglucagon gene expression by β -catenin and glycogen synthase kinase-3 β Journal of Biological Chemistry 2005 280 2 1457 1464 2-s2.0-12544254474 10.1074/jbc.M411487200
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.2
, pp. 1457-1464
-
-
Yi, F.1
Brubaker, P.L.2
Jin, T.3
-
101
-
-
84871596296
-
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand
-
10.1016/j.cell.2012.10.053
-
Boj S. F., van Es J. H., Huch M., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell 2012 151 7 1595 1607 10.1016/j.cell.2012.10.053
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1595-1607
-
-
Boj, S.F.1
Van Es, J.H.2
Huch, M.3
-
102
-
-
84866107559
-
Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice
-
10.1007/s00125-012-2600-7
-
da Silva Xavier G., Mondragon A., Sun G., Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice. Diabetologia 2012 55 10 2667 2676 10.1007/s00125-012-2600-7
-
(2012)
Diabetologia
, vol.55
, Issue.10
, pp. 2667-2676
-
-
Da Silva Xavier, G.1
Mondragon, A.2
Sun, G.3
-
103
-
-
80052527283
-
Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism
-
2-s2.0-80052527283 10.1101/gr.123745.111
-
Savic D., Ye H., Aneas I., Park S.-Y., Bell G. I., Nobrega M. A., Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism. Genome Research 2011 21 9 1417 1425 2-s2.0-80052527283 10.1101/gr.123745.111
-
(2011)
Genome Research
, vol.21
, Issue.9
, pp. 1417-1425
-
-
Savic, D.1
Ye, H.2
Aneas, I.3
Park, S.-Y.4
Bell, G.I.5
Nobrega, M.A.6
-
104
-
-
33750889376
-
Transcription factor TCF7L2 genetic study in the French population: Expression in human β-cells and adipose tissue and strong association with type 2 diabetes
-
DOI 10.2337/db06-0474
-
Cauchi S., Meyre D., Dina C., Choquet H., Samson C., Gallina S., Balkau B., Charpentier G., Pattou F., Stetsyuk V., Scharfmann R., Staels B., Frühbeck G., Froguel P., Transcription factor TCF7L2 genetic study in the French population: expression in human β -cells and adipose tissue and strong association with type 2 diabetes. Diabetes 2006 55 10 2903 2908 2-s2.0-33750889376 10.2337/db06-0474 (Pubitemid 44923694)
-
(2006)
Diabetes
, vol.55
, Issue.10
, pp. 2903-2908
-
-
Cauchi, S.1
Meyre, D.2
Dina, C.3
Choquet, H.4
Samson, C.5
Gallina, S.6
Balkau, B.7
Charpentier, G.8
Pattou, F.9
Stetsyuk, V.10
Scharfmann, R.11
Staels, B.12
Fruhbeck, G.13
Froguel, P.14
-
105
-
-
84868035640
-
Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism
-
10.2337/db12-0239
-
Kaminska D., Kuulasmaa T., Venesmaa S., Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism. Diabetes 2012 61 11 2807 2813 10.2337/db12-0239
-
(2012)
Diabetes
, vol.61
, Issue.11
, pp. 2807-2813
-
-
Kaminska, D.1
Kuulasmaa, T.2
Venesmaa, S.3
-
106
-
-
70349636577
-
Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes
-
article e7231 2-s2.0-70349636577 10.1371/journal.pone.0007231
-
Prokunina-Olsson L., Kaplan L. M., Schadt E. E., Collins F. S., Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes. PLoS ONE 2009 4 9, article e7231 2-s2.0-70349636577 10.1371/journal.pone.0007231
-
(2009)
PLoS ONE
, vol.4
, Issue.9
-
-
Prokunina-Olsson, L.1
Kaplan, L.M.2
Schadt, E.E.3
Collins, F.S.4
-
107
-
-
70349569023
-
Tissue-specific alternative splicing of TCF7L2
-
2-s2.0-70349569023 10.1093/hmg/ddp321
-
Prokunina-Olsson L., Welch C., Hansson O., Adhikari N., Scott L. J., Usher N., Tong M., Sprau A., Swift A., Bonnycastle L. L., Erdos M. R., He Z., Saxena R., Harmon B., Kotova O., Hoffman E. P., Altshuler D., Groop L., Boehnke M., Collins F. S., Hall J. L., Tissue-specific alternative splicing of TCF7L2. Human Molecular Genetics 2009 18 20 3795 3804 2-s2.0-70349569023 10.1093/hmg/ddp321
-
(2009)
Human Molecular Genetics
, vol.18
, Issue.20
, pp. 3795-3804
-
-
Prokunina-Olsson, L.1
Welch, C.2
Hansson, O.3
Adhikari, N.4
Scott, L.J.5
Usher, N.6
Tong, M.7
Sprau, A.8
Swift, A.9
Bonnycastle, L.L.10
Erdos, M.R.11
He, Z.12
Saxena, R.13
Harmon, B.14
Kotova, O.15
Hoffman, E.P.16
Altshuler, D.17
Groop, L.18
Boehnke, M.19
Collins, F.S.20
Hall, J.L.21
more..
-
108
-
-
34547585382
-
Variation in TCF7L2 influences therapeutic response to sulfonylureas: A GoDARTs study
-
DOI 10.2337/db07-0440
-
Pearson E. R., Donnelly L. A., Kimber C., Whitley A., Doney A. S. F., McCarthy M. I., Hattersley A. T., Morris A. D., Palmer C. N. A., Variation in TCF7L2 influences therapeutic response to sulfonylureas: a GoDARTs study. Diabetes 2007 56 8 2178 2182 2-s2.0-34547585382 10.2337/db07-0440 (Pubitemid 47195841)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2178-2182
-
-
Pearson, E.R.1
Donnelly, L.A.2
Kimber, C.3
Whitley, A.4
Doney, A.S.F.5
McCarthy, M.I.6
Hattersley, A.T.7
Morris, A.D.8
Palmer, C.N.A.9
-
109
-
-
79951960556
-
TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes
-
article 30 2-s2.0-79951960556 10.1186/1471-2350-12-30
-
Holstein A., Hahn M., Körner A., Stumvoll M., Kovacs P., TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes. BMC Medical Genetics 2011 12, article 30 2-s2.0-79951960556 10.1186/1471-2350-12-30
-
(2011)
BMC Medical Genetics
, vol.12
-
-
Holstein, A.1
Hahn, M.2
Körner, A.3
Stumvoll, M.4
Kovacs, P.5
-
111
-
-
77957689894
-
Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo
-
2-s2.0-77957689894 10.1007/s00125-010-1852-3
-
Zhao J., Schug J., Li M., Kaestner K. H., Grant S. F. A., Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo. Diabetologia 2010 53 11 2340 2346 2-s2.0-77957689894 10.1007/s00125-010-1852-3
-
(2010)
Diabetologia
, vol.53
, Issue.11
, pp. 2340-2346
-
-
Zhao, J.1
Schug, J.2
Li, M.3
Kaestner, K.H.4
Grant, S.F.A.5
-
112
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
DOI 10.1126/science.281.5382.1509
-
He T.-C., Sparks A. B., Rago C., Hermeking H., Zawel L., Da Costa L. T., Morin P. J., Vogelstein B., Kinzler K. W., Identification of c-MYC as a target of the APC pathway. Science 1998 281 5382 1509 1512 2-s2.0-0032483439 10.1126/science.281.5382.1509 (Pubitemid 28425575)
-
(1998)
Science
, vol.281
, Issue.5382
, pp. 1509-1512
-
-
He, T.-C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
Da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
113
-
-
84868194089
-
Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: The Breast Cancer Health Disparities study
-
10.1007/s10549-012-2299-7
-
Connor A. E., Baumgartner R. N., Baumgartner K. B., Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities study. Breast Cancer Research and Treatment 2012 136 2 593 602 10.1007/s10549-012-2299-7
-
(2012)
Breast Cancer Research and Treatment
, vol.136
, Issue.2
, pp. 593-602
-
-
Connor, A.E.1
Baumgartner, R.N.2
Baumgartner, K.B.3
-
114
-
-
84856697168
-
The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: A meta-analysis and an individual study
-
2-s2.0-84856697168 10.1007/s00125-011-2378-z
-
Lukacs K., Hosszufalusi N., Dinya E., Bakacs M., Madacsy L., Panczel P., The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: a meta-analysis and an individual study. Diabetologia 2012 55 3 689 693 2-s2.0-84856697168 10.1007/s00125-011-2378-z
-
(2012)
Diabetologia
, vol.55
, Issue.3
, pp. 689-693
-
-
Lukacs, K.1
Hosszufalusi, N.2
Dinya, E.3
Bakacs, M.4
Madacsy, L.5
Panczel, P.6
-
115
-
-
84891361596
-
Genetic modifiers of cystic fibrosis-related diabetes
-
10.2337/db13-0510
-
Blackman S. M., Commander C. W., Watson C., Genetic modifiers of cystic fibrosis-related diabetes. Diabetes 2013 62 10 3627 3635 10.2337/db13-0510
-
(2013)
Diabetes
, vol.62
, Issue.10
, pp. 3627-3635
-
-
Blackman, S.M.1
Commander, C.W.2
Watson, C.3
-
116
-
-
68449090520
-
A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis
-
2-s2.0-68449090520 10.1007/s00125-009-1436-2
-
Blackman S. M., Hsu S., Ritter S. E., Naughton K. M., Wright F. A., Drumm M. L., Knowles M. R., Cutting G. R., A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis. Diabetologia 2009 52 9 1858 1865 2-s2.0-68449090520 10.1007/s00125-009-1436-2
-
(2009)
Diabetologia
, vol.52
, Issue.9
, pp. 1858-1865
-
-
Blackman, S.M.1
Hsu, S.2
Ritter, S.E.3
Naughton, K.M.4
Wright, F.A.5
Drumm, M.L.6
Knowles, M.R.7
Cutting, G.R.8
-
117
-
-
84871012874
-
Association between the IVS4G>T mutation in the TCF7L2 gene and susceptibility to diabetes in cystic fibrosis patients
-
article 561 10.1186/1756-0500-5-561
-
Furgeri D. T., Marson F. A., Ribeiro A. F., Association between the IVS4G>T mutation in the TCF7L2 gene and susceptibility to diabetes in cystic fibrosis patients. BMC Research Notes 2012 5, article 561 10.1186/1756-0500-5- 561
-
(2012)
BMC Research Notes
, vol.5
-
-
Furgeri, D.T.1
Marson, F.A.2
Ribeiro, A.F.3
-
118
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
DOI 10.1038/ng2048, PII NG2048
-
Dina C., Meyre D., Gallina S., Durand E., Körner A., Jacobson P., Carlsson L. M. S., Kiess W., Vatin V., Lecoeur C., Delplanque J., Vaillant E., Pattou F., Ruiz J., Weill J., Levy-Marchal C., Horber F., Potoczna N., Hercberg S., Le Stunff C., Bougnères P., Kovacs P., Marre M., Balkau B., Cauchi S., Chèvre J.-C., Froguel P., Variation in FTO contributes to childhood obesity and severe adult obesity. Nature Genetics 2007 39 6 724 726 2-s2.0-34249777814 10.1038/ng2048 (Pubitemid 46848595)
-
(2007)
Nature Genetics
, vol.39
, Issue.6
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
Carlsson, L.M.S.7
Kiess, W.8
Vatin, V.9
Lecoeur, C.10
Delplanque, J.11
Vaillant, E.12
Pattou, F.13
Ruiz, J.14
Weill, J.15
Levy-Marchal, C.16
Horber, F.17
Potoczna, N.18
Hercberg, S.19
Le Stunff, C.20
Bougneres, P.21
Kovacs, P.22
Marre, M.23
Balkau, B.24
Cauchi, S.25
Chevre, J.-C.26
Froguel, P.27
more..
-
119
-
-
84876567174
-
Genetics of obesity and type 2 diabetes in African Americans
-
396416 10.1155/2013/396416
-
McCormack S., Grant S. F., Genetics of obesity and type 2 diabetes in African Americans. Journal of Obesity 2013 2013 12 396416 10.1155/2013/396416
-
(2013)
Journal of Obesity
, vol.2013
, pp. 12
-
-
McCormack, S.1
Grant, S.F.2
-
120
-
-
0035428060
-
Beyond body mass index
-
Prentice A. M., Jebb S. A., Beyond body mass index. Obesity Reviews 2001 2 3 141 147 2-s2.0-0035428060 (Pubitemid 33755907)
-
(2001)
Obesity Reviews
, vol.2
, Issue.3
, pp. 141-147
-
-
Prentice, A.M.1
Jebb, S.A.2
-
121
-
-
84862822438
-
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations
-
2-s2.0-84857643667 10.1038/ng.1086
-
Okada Y., Kubo M., Ohmiya H., Takahashi A., Kumasaka N., Hosono N., Maeda S., Wen W., Dorajoo R., Go M. J., Zheng W., Kato N., Wu J.-Y., Lu Q., Tsunoda T., Yamamoto K., Nakamura Y., Kamatani N., Tanaka T., Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations. Nature Genetics 2012 44 3 302 306 2-s2.0-84857643667 10.1038/ng.1086
-
(2012)
Nature Genetics
, vol.44
, Issue.3
, pp. 302-306
-
-
Okada, Y.1
Kubo, M.2
Ohmiya, H.3
Takahashi, A.4
Kumasaka, N.5
Hosono, N.6
Maeda, S.7
Wen, W.8
Dorajoo, R.9
Go, M.J.10
Zheng, W.11
Kato, N.12
Wu, J.-Y.13
Lu, Q.14
Tsunoda, T.15
Yamamoto, K.16
Nakamura, Y.17
Kamatani, N.18
Tanaka, T.19
-
122
-
-
84862777036
-
Meta-analysis identifies common variants associated with body mass index in East Asians
-
10.1038/ng.1087
-
Wen W., Cho Y. S., Zheng W., Meta-analysis identifies common variants associated with body mass index in East Asians. Nature Genetics 2012 44 3 307 311 10.1038/ng.1087
-
(2012)
Nature Genetics
, vol.44
, Issue.3
, pp. 307-311
-
-
Wen, W.1
Cho, Y.S.2
Zheng, W.3
-
123
-
-
77957105975
-
Association of FTO gene variants with adiposity in African-American adolescents
-
2-s2.0-77957105975 10.1038/oby.2010.82
-
Bollepalli S., Dolan L. M., Deka R., Martin L. J., Association of FTO gene variants with adiposity in African-American adolescents. Obesity 2010 18 10 1959 1963 2-s2.0-77957105975 10.1038/oby.2010.82
-
(2010)
Obesity
, vol.18
, Issue.10
, pp. 1959-1963
-
-
Bollepalli, S.1
Dolan, L.M.2
Deka, R.3
Martin, L.J.4
-
124
-
-
34547625955
-
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
-
DOI 10.1371/journal.pgen.0030115
-
Scuteri A., Sanna S., Chen W.-M., Uda M., Albai G., Strait J., Najjar S., Nagaraja R., Orrú M., Usala G., Dei M., Lai S., Maschio A., Busonero F., Mulas A., Ehret G. B., Fink A. A., Weder A. B., Cooper R. S., Galan P., Chakravarti A., Schlessinger D., Cao A., Lakatta E., Abecasis G. R., Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genetics 2007 3 7, article e115 2-s2.0-44449162574 10.1371/journal.pgen.0030115 (Pubitemid 47203970)
-
(2007)
PLoS Genetics
, vol.3
, Issue.7
, pp. 1200-1210
-
-
Scuteri, A.1
Sanna, S.2
Chen, W.-M.3
Uda, M.4
Albai, G.5
Strait, J.6
Najjar, S.7
Nagaraja, R.8
Orru, M.9
Usala, G.10
Dei, M.11
Lai, S.12
Maschio, A.13
Busonero, F.14
Mulas, A.15
Ehret, G.B.16
Fink, A.A.17
Weder, A.B.18
Cooper, R.S.19
Galan, P.20
Chakravarti, A.21
Schlessinger, D.22
Cao, A.23
Lakatta, E.24
Abecasis, G.R.25
more..
-
125
-
-
77954513650
-
Fine mapping of the association with obesity at the FTO locus in African-derived populations
-
2-s2.0-77954513650 10.1093/hmg/ddq178
-
Hassanein M. T., Lyon H. N., Nguyen T. T., Akylbekova E. L., Waters K., Lettre G., Tayo B., Forrester T., Sarpong D. F., Stram D. O., Butler J. L., Wilks R., Liu J., Le Marchand L., Kolonel L. N., Zhu X., Henderson B., Cooper R., McKenzie C., Taylor H. A. Jr., Haiman C. A., Hirschhorn J. N., Fine mapping of the association with obesity at the FTO locus in African-derived populations. Human Molecular Genetics 2010 19 14 2907 2916 2-s2.0-77954513650 10.1093/hmg/ddq178
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.14
, pp. 2907-2916
-
-
Hassanein, M.T.1
Lyon, H.N.2
Nguyen, T.T.3
Akylbekova, E.L.4
Waters, K.5
Lettre, G.6
Tayo, B.7
Forrester, T.8
Sarpong, D.F.9
Stram, D.O.10
Butler, J.L.11
Wilks, R.12
Liu, J.13
Le Marchand, L.14
Kolonel, L.N.15
Zhu, X.16
Henderson, B.17
Cooper, R.18
McKenzie, C.19
Taylor Jr., H.A.20
Haiman, C.A.21
Hirschhorn, J.N.22
more..
-
126
-
-
77953191271
-
FTO genetic variation and association with obesity in West Africans and African Americans
-
2-s2.0-77953191271 10.2337/db09-1252
-
Adeyemo A., Chen G., Zhou J., Shriner D., Doumatey A., Huang H., Rotimi C., FTO genetic variation and association with obesity in West Africans and African Americans. Diabetes 2010 59 6 1549 1554 2-s2.0-77953191271 10.2337/db09-1252
-
(2010)
Diabetes
, vol.59
, Issue.6
, pp. 1549-1554
-
-
Adeyemo, A.1
Chen, G.2
Zhou, J.3
Shriner, D.4
Doumatey, A.5
Huang, H.6
Rotimi, C.7
-
127
-
-
84862213947
-
Appetite regulation genes are associated with body mass index in black South African adolescents: A genetic association study
-
article e000873 10.1136/bmjopen-2012-000873
-
Lombard Z., Crowther N. J., van der Merwe L., Appetite regulation genes are associated with body mass index in black South African adolescents: a genetic association study. BMJ Open 2012 2 3, article e000873 10.1136/bmjopen-2012-000873
-
(2012)
BMJ Open
, vol.2
, Issue.3
-
-
Lombard, Z.1
Crowther, N.J.2
Van Der Merwe, L.3
-
128
-
-
0036220971
-
The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster
-
DOI 10.1007/s00335-001-2142-7
-
Peters T., Ausmeier K., Dildrop R., Rüther U., The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster. Mammalian Genome 2002 13 4 186 188 2-s2.0-0036220971 10.1007/s00335-001-2142-7 (Pubitemid 34299029)
-
(2002)
Mammalian Genome
, vol.13
, Issue.4
, pp. 186-188
-
-
Peters, T.1
Ausmeier, K.2
Dildrop, R.3
Ruther, U.4
-
129
-
-
36749041363
-
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
-
DOI 10.1126/science.1151710
-
Gerken T., Girard C. A., Tung Y.-C. L., Webby C. J., Saudek V., Hewitson K. S., Yeo G. S. H., McDonough M. A., Cunliffe S., McNeill L. A., Galvanovskis J., Rorsman P., Robins P., Prieur X., Coll A. P., Ma M., Jovanovic Z., Farooqi I. S., Sedgwick B., Barroso I., Lindahl T., Ponting C. P., Ashcroft F. M., O'Rahilly S., Schofield C. J., The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007 318 5855 1469 1472 2-s2.0-36749041363 10.1126/science.1151710 (Pubitemid 350208961)
-
(2007)
Science
, vol.318
, Issue.5855
, pp. 1469-1472
-
-
Gerken, T.1
Girard, C.A.2
Tung, Y.-C.L.3
Webby, C.J.4
Saudek, V.5
Hewitson, K.S.6
Yeo, G.S.H.7
McDonough, M.A.8
Cunliffe, S.9
McNeill, L.A.10
Galvanovskis, J.11
Rorsman, P.12
Robins, P.13
Prieur, X.14
Coll, A.P.15
Ma, M.16
Jovanovic, Z.17
Farooqi, I.S.18
Sedgwick, B.19
Barroso, I.20
Lindahl, T.21
Ponting, C.P.22
Ashcroft, F.M.23
O'Rahilly, S.24
Schofield, C.J.25
more..
-
130
-
-
38649130998
-
The FTO gene, implicated in human obesity, is found only in vertebrates and marine algae
-
2-s2.0-38649130998 10.1007/s00239-007-9059-z
-
Robbens S., Rouzé P., Cock J. M., Spring J., Worden A. Z., Van De Peer Y., The FTO gene, implicated in human obesity, is found only in vertebrates and marine algae. Journal of Molecular Evolution 2008 66 1 80 84 2-s2.0-38649130998 10.1007/s00239-007-9059-z
-
(2008)
Journal of Molecular Evolution
, vol.66
, Issue.1
, pp. 80-84
-
-
Robbens, S.1
Rouzé, P.2
Cock, J.M.3
Spring, J.4
Worden, A.Z.5
Van De Peer, Y.6
-
131
-
-
79952474482
-
From GWAS to biology: Lessons from FTO
-
2-s2.0-79952474482 10.1111/j.1749-6632.2010.05903.x
-
Tung Y.-C. L., Yeo G. S. H., From GWAS to biology: lessons from FTO. Annals of the New York Academy of Sciences 2011 1220 1 162 171 2-s2.0-79952474482 10.1111/j.1749-6632.2010.05903.x
-
(2011)
Annals of the New York Academy of Sciences
, vol.1220
, Issue.1
, pp. 162-171
-
-
Tung, Y.-C.L.1
Yeo, G.S.H.2
-
132
-
-
78649459183
-
Overexpression of FTO leads to increased food intake and results in obesity
-
2-s2.0-78649459183 10.1038/ng.713
-
Church C., Moir L., McMurray F., Girard C., Banks G. T., Teboul L., Wells S., Brüning J. C., Nolan P. M., Ashcroft F. M., Cox R. D., Overexpression of FTO leads to increased food intake and results in obesity. Nature Genetics 2010 42 12 1086 1092 2-s2.0-78649459183 10.1038/ng.713
-
(2010)
Nature Genetics
, vol.42
, Issue.12
, pp. 1086-1092
-
-
Church, C.1
Moir, L.2
McMurray, F.3
Girard, C.4
Banks, G.T.5
Teboul, L.6
Wells, S.7
Brüning, J.C.8
Nolan, P.M.9
Ashcroft, F.M.10
Cox, R.D.11
-
133
-
-
57749121512
-
An obesity-associated FTO gene variant and increased energy intake in children
-
2-s2.0-57749121512 10.1056/NEJMoa0803839
-
Cecil J. E., Tavendale R., Watt P., Hetherington M. M., Palmer C. N. A., An obesity-associated FTO gene variant and increased energy intake in children. The New England Journal of Medicine 2008 359 24 2558 2566 2-s2.0-57749121512 10.1056/NEJMoa0803839
-
(2008)
The New England Journal of Medicine
, vol.359
, Issue.24
, pp. 2558-2566
-
-
Cecil, J.E.1
Tavendale, R.2
Watt, P.3
Hetherington, M.M.4
Palmer, C.N.A.5
-
134
-
-
51649128621
-
Obesity associated genetic variation in FTO is associated with diminished satiety
-
2-s2.0-51649128621 10.1210/jc.2008-0472
-
Wardle J., Carnell S., Haworth C. M. A., Farooqi I. S., O'Rahilly S., Plomin R., Obesity associated genetic variation in FTO is associated with diminished satiety. Journal of Clinical Endocrinology and Metabolism 2008 93 9 3640 3643 2-s2.0-51649128621 10.1210/jc.2008-0472
-
(2008)
Journal of Clinical Endocrinology and Metabolism
, vol.93
, Issue.9
, pp. 3640-3643
-
-
Wardle, J.1
Carnell, S.2
Haworth, C.M.A.3
Farooqi, I.S.4
O'Rahilly, S.5
Plomin, R.6
-
135
-
-
70149100469
-
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene
-
2-s2.0-70149100469 10.1371/journal.pgen.1000599 e1000599
-
Church C., Lee S., Bagg E. A. L., McTaggart J. S., Deacon R., Gerken T., Lee A., Moir L., Mecinović J., Quwailid M. M., Schofield C. J., Ashcroft F. M., Cox R. D., A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS Genetics 2009 5 8 2-s2.0-70149100469 10.1371/journal.pgen.1000599 e1000599
-
(2009)
PLoS Genetics
, vol.5
, Issue.8
-
-
Church, C.1
Lee, S.2
Bagg, E.A.L.3
McTaggart, J.S.4
Deacon, R.5
Gerken, T.6
Lee, A.7
Moir, L.8
Mecinović, J.9
Quwailid, M.M.10
Schofield, C.J.11
Ashcroft, F.M.12
Cox, R.D.13
-
136
-
-
67349211789
-
Inactivation of the FTO gene protects from obesity
-
2-s2.0-67349211789 10.1038/nature07848
-
Fischer J., Koch L., Emmerling C., Vierkotten J., Peters T., Brüning J. C., Rüther U., Inactivation of the FTO gene protects from obesity. Nature 2009 458 7240 894 898 2-s2.0-67349211789 10.1038/nature07848
-
(2009)
Nature
, vol.458
, Issue.7240
, pp. 894-898
-
-
Fischer, J.1
Koch, L.2
Emmerling, C.3
Vierkotten, J.4
Peters, T.5
Brüning, J.C.6
Rüther, U.7
-
137
-
-
84862113496
-
Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: The 1946 British Birth Cohort study
-
10.3945/ajcn.111.027870
-
Elks C. E., Loos R. J., Hardy R., Adult obesity susceptibility variants are associated with greater childhood weight gain and a faster tempo of growth: the 1946 British Birth Cohort study. The American Journal of Clinical Nutrition 2012 95 5 1150 1156 10.3945/ajcn.111.027870
-
(2012)
The American Journal of Clinical Nutrition
, vol.95
, Issue.5
, pp. 1150-1156
-
-
Elks, C.E.1
Loos, R.J.2
Hardy, R.3
-
138
-
-
77953270825
-
Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth
-
1000284 2-s2.0-77953270825 10.1371/journal.pmed.1000284
-
Elks C. E., Loos R. J. F., Sharp S. J., Langenberg C., Ring S. M., Timpson N. J., Ness A. R., Smith G. D., Dunger D. B., Wareham N. J., Ong K. K., Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. PLoS Medicine 2010 7 5 1000284 2-s2.0-77953270825 10.1371/journal.pmed.1000284
-
(2010)
PLoS Medicine
, vol.7
, Issue.5
-
-
Elks, C.E.1
Loos, R.J.F.2
Sharp, S.J.3
Langenberg, C.4
Ring, S.M.5
Timpson, N.J.6
Ness, A.R.7
Smith, G.D.8
Dunger, D.B.9
Wareham, N.J.10
Ong, K.K.11
-
139
-
-
77949894041
-
Life course variations in the associations between FTO and MC4R gene variants and body size
-
2-s2.0-77949894041 10.1093/hmg/ddp504
-
Hardy R., Wills A. K., Wong A., Elks C. E., Wareham N. J., Loos R. J. F., Kuh D., Ong K. K., Life course variations in the associations between FTO and MC4R gene variants and body size. Human Molecular Genetics 2010 19 3 545 552 2-s2.0-77949894041 10.1093/hmg/ddp504
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.3
, pp. 545-552
-
-
Hardy, R.1
Wills, A.K.2
Wong, A.3
Elks, C.E.4
Wareham, N.J.5
Loos, R.J.F.6
Kuh, D.7
Ong, K.K.8
|