메뉴 건너뛰기




Volumn 4, Issue 9, 2009, Pages

Alternative splicing of TCF7L2 gene in omental and subcutaneous adipose tissue and risk of type 2 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; TRANSCRIPTION FACTOR 7 LIKE 2; T CELL FACTOR PROTEIN; TCF7L2 TRANSCRIPTION FACTOR;

EID: 70349636577     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007231     Document Type: Article
Times cited : (37)

References (27)
  • 1
    • 32544451924 scopus 로고    scopus 로고
    • Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
    • Grant SF, Thorleifsson G, Reynisdottir I, Benediktsson R, Manolescu A, et al. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 38: 320-323.
    • (2006) Nat Genet , vol.38 , pp. 320-323
    • Grant, S.F.1    Thorleifsson, G.2    Reynisdottir, I.3    Benediktsson, R.4    Manolescu, A.5
  • 2
    • 33750587754 scopus 로고    scopus 로고
    • Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample
    • Scott LJ, Bonnycastle LL, Willer CJ, Sprau AG, Jackson AU, et al. (2006) Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample. Diabetes 55: 2649-2653.
    • (2006) Diabetes , vol.55 , pp. 2649-2653
    • Scott, L.J.1    Bonnycastle, L.L.2    Willer, C.J.3    Sprau, A.G.4    Jackson, A.U.5
  • 3
    • 33750892139 scopus 로고    scopus 로고
    • Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
    • Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, et al. (2006) Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals. Diabetes 55: 2890-2895.
    • (2006) Diabetes , vol.55 , pp. 2890-2895
    • Saxena, R.1    Gianniny, L.2    Burtt, N.P.3    Lyssenko, V.4    Giuducci, C.5
  • 4
    • 33750602980 scopus 로고    scopus 로고
    • Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk
    • Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, et al. (2006) Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes 55: 2640-2644.
    • (2006) Diabetes , vol.55 , pp. 2640-2644
    • Groves, C.J.1    Zeggini, E.2    Minton, J.3    Frayling, T.M.4    Weedon, M.N.5
  • 5
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434: 843-850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 6
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • He TC, Sparks AB, Rago C, Hermeking H, Zawel L, et al. (1998) Identification of c-MYC as a target of the APC pathway. Science 281: 1509-1512.
    • (1998) Science , vol.281 , pp. 1509-1512
    • He, T.C.1    Sparks, A.B.2    Rago, C.3    Hermeking, H.4    Zawel, L.5
  • 7
    • 33751018274 scopus 로고    scopus 로고
    • Rapid loss of intestinal crypts upon conditional deletion of the Wnt/ Tcf-4 target gene c-Myc
    • Muncan V, Sansom OJ, Tertoolen L, Phesse TJ, Begthel H, et al. (2006) Rapid loss of intestinal crypts upon conditional deletion of the Wnt/ Tcf-4 target gene c-Myc. Mol Cell Biol 26: 8418-8426.
    • (2006) Mol Cell Biol , vol.26 , pp. 8418-8426
    • Muncan, V.1    Sansom, O.J.2    Tertoolen, L.3    Phesse, T.J.4    Begthel, H.5
  • 8
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F (1999) Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 9
    • 0035395874 scopus 로고    scopus 로고
    • Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
    • Merrill BJ, Gat U, DasGupta R, Fuchs E (2001) Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev 15: 1688-1705.
    • (2001) Genes Dev , vol.15 , pp. 1688-1705
    • Merrill, B.J.1    Gat, U.2    DasGupta, R.3    Fuchs, E.4
  • 11
    • 12344304272 scopus 로고    scopus 로고
    • Metabolic syndrome: Definition, pathophysiology, and mechanisms
    • Miranda PJ, DeFronzo RA, Califf RM, Guyton JR (2005) Metabolic syndrome: definition, pathophysiology, and mechanisms. Am Heart J 149: 33-45.
    • (2005) Am Heart J , vol.149 , pp. 33-45
    • Miranda, P.J.1    DeFronzo, R.A.2    Califf, R.M.3    Guyton, J.R.4
  • 12
    • 33746075560 scopus 로고    scopus 로고
    • TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program
    • Florez JC, Jablonski KA, Bayley N, Pollin TI, de Bakker PI, et al. (2006) TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl J Med 355: 241-250.
    • (2006) N Engl J Med , vol.355 , pp. 241-250
    • Florez, J.C.1    Jablonski, K.A.2    Bayley, N.3    Pollin, T.I.4    de Bakker, P.I.5
  • 13
    • 33750889376 scopus 로고    scopus 로고
    • Transcription factor TCF7L2 genetic study in the French population: Expression in human beta-cells and adipose tissue and strong association with type 2 diabetes
    • Cauchi S, Meyre D, Dina C, Choquet H, Samson C, et al. (2006) Transcription factor TCF7L2 genetic study in the French population: expression in human beta-cells and adipose tissue and strong association with type 2 diabetes. Diabetes 55: 2903-2908.
    • (2006) Diabetes , vol.55 , pp. 2903-2908
    • Cauchi, S.1    Meyre, D.2    Dina, C.3    Choquet, H.4    Samson, C.5
  • 14
    • 33845534950 scopus 로고    scopus 로고
    • TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population: The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study
    • Cauchi S, Meyre D, Choquet H, Dina C, Born C, et al. (2006) TCF7L2 Variation Predicts Hyperglycemia Incidence in a French General Population: The Data From an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) Study. Diabetes 55: 3189-3192.
    • (2006) Diabetes , vol.55 , pp. 3189-3192
    • Cauchi, S.1    Meyre, D.2    Choquet, H.3    Dina, C.4    Born, C.5
  • 15
    • 39449114267 scopus 로고    scopus 로고
    • Cauchi S, Choquet H, Gutierrez-Aguilar R, Capel F, Grau K, et al. (2008) Effects of TCF7L2 polymorphisms on obesity in European populations. Obesity (Silver Spring) 16: 476-482.
    • Cauchi S, Choquet H, Gutierrez-Aguilar R, Capel F, Grau K, et al. (2008) Effects of TCF7L2 polymorphisms on obesity in European populations. Obesity (Silver Spring) 16: 476-482.
  • 17
    • 33646368404 scopus 로고    scopus 로고
    • A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus
    • Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, et al. (2006) A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. Nat Genet 38: 550-555.
    • (2006) Nat Genet , vol.38 , pp. 550-555
    • Graham, R.R.1    Kozyrev, S.V.2    Baechler, E.C.3    Reddy, M.V.4    Plenge, R.M.5
  • 18
    • 34447131039 scopus 로고    scopus 로고
    • Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent
    • Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, et al. (2007) Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia 50: 1621-1630.
    • (2007) Diabetologia , vol.50 , pp. 1621-1630
    • Elbein, S.C.1    Chu, W.S.2    Das, S.K.3    Yao-Borengasser, A.4    Hasstedt, S.J.5
  • 19
    • 34547702501 scopus 로고    scopus 로고
    • Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes
    • Lyssenko V, Lupi R, Marchetti P, Del Guerra S, Orho-Melander M, et al. (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes. J Clin Invest 117: 2155-2163.
    • (2007) J Clin Invest , vol.117 , pp. 2155-2163
    • Lyssenko, V.1    Lupi, R.2    Marchetti, P.3    Del Guerra, S.4    Orho-Melander, M.5
  • 22
    • 70349636642 scopus 로고    scopus 로고
    • http://hapmap.org/.
  • 24
    • 53749085475 scopus 로고    scopus 로고
    • Wegner L, Hussain MS, Pilgaard K, Hansen T, Pedersen O, et al. (2008) Impact of TCF7L2 rs7903146 on Insulin Secretion and Action in Young and Elderly Danish Twins. J Clin Endocrinol Metab.
    • Wegner L, Hussain MS, Pilgaard K, Hansen T, Pedersen O, et al. (2008) Impact of TCF7L2 rs7903146 on Insulin Secretion and Action in Young and Elderly Danish Twins. J Clin Endocrinol Metab.
  • 25
    • 48849095822 scopus 로고    scopus 로고
    • TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus
    • Kovacs P, Berndt J, Ruschke K, Kloting N, Schon MR, et al. (2008) TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus. Metabolism 57: 1227-1231.
    • (2008) Metabolism , vol.57 , pp. 1227-1231
    • Kovacs, P.1    Berndt, J.2    Ruschke, K.3    Kloting, N.4    Schon, M.R.5
  • 26
    • 33745542960 scopus 로고    scopus 로고
    • C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila
    • Fang M, Li J, Blauwkamp T, Bhambhani C, Campbell N, et al. (2006) C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila. EMBO J 25: 2735-2745.
    • (2006) EMBO J , vol.25 , pp. 2735-2745
    • Fang, M.1    Li, J.2    Blauwkamp, T.3    Bhambhani, C.4    Campbell, N.5
  • 27
    • 33747865461 scopus 로고    scopus 로고
    • Applications for protein sequence-function evolution data: MRNA/protein expression analysis and coding SNP scoring tools
    • Thomas PD, Kejariwal A, Guo N, Mi H, Campbell MJ, et al. (2006) Applications for protein sequence-function evolution data: mRNA/protein expression analysis and coding SNP scoring tools. Nucleic Acids Res 34: W645-650.
    • (2006) Nucleic Acids Res , vol.34
    • Thomas, P.D.1    Kejariwal, A.2    Guo, N.3    Mi, H.4    Campbell, M.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.