The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster

Mammalian Genome

Volumn 13, Issue 4, 2002, Pages 186-188

  Peters, Thomas ^a   Ausmeier, Katrin ^b   Dildrop, Renate ^a   Rüther, Ulrich ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN IROQUOIS B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CHROMOSOME 8; CRANIOFACIAL MALFORMATION; DELETION MUTANT; EMBRYO AXIS; EXTRACELLULAR MATRIX; GENE CLUSTER; GENE INSERTION; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; HOMOZYGOSITY; MOUSE; NONHUMAN; POLYDACTYLY; POLYMERASE CHAIN REACTION; STRUCTURE ANALYSIS; SYNDACTYLY; THYMUS HYPERPLASIA; TOE MALFORMATION; TRANSGENE; TRANSGENIC MOUSE;

ANIMALS; GENE DELETION; HOMEODOMAIN PROTEINS; MICE; MULTIGENE FAMILY; PHYSICAL CHROMOSOME MAPPING; PROTEINS; TRANSCRIPTION FACTORS;

ANIMALIA; INSERTION SEQUENCES; MUS MUSCULUS;

EID: 0036220971     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00335-001-2142-7     Document Type: Article

References (16)

1. High-resolution mapping of a linkage group on mouse chromosome 8 conserved on human chromosome 16Q
2. Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression
3. The Iroquois family of genes: From body building to neural patterning
4. A physical map of 30,000 human genes
5. The expression pattern of nodal and lefty in the mouse mutant Ft suggests a function in the establishment of handedness
6. Retinitis pigmentosa GTPase regulator (RPGRr)-interacting protein is stably associated with the photoreceptor ciliary axoneme and anchors RPGR to the connecting cilium
7. Gene and cluster-specific expression of the Iroquois family members during mouse development
8. Initial sequencing and analysis of the human genome
9. Ft1, a novel gene related to ubiquitin-conjugating enzymes, is deleted in the Fused toes mouse mutation
10. A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X-linked retinitis pigmentosa (RP3)
11. A YAC-based physical map of the mouse genome
12. Cloning of Fatso (Fto), a novel gene deleted by the Fused toes (Ft) mouse mutation
13. Organization of mouse Iroquois homeobox genes in two clusters suggests a conserved regulation and function in vertebrate development
14. Programmed cell death is affected in the novel mouse mutant Fused toes (Ft)
15. The sequence of the human genome