-
1
-
-
0025283961
-
Developmental cell death: Morphological diversity and multiple mechanisms
-
Clarke PG. Developmental cell death: morphological diversity and multiple mechanisms. Anat Embryol 1990; 181(3): 195-213.
-
(1990)
Anat Embryol
, vol.181
, Issue.3
, pp. 195-213
-
-
Clarke, P.G.1
-
2
-
-
72149127389
-
The alpha-secretase-derived N-terminal product of cellular prion, N1: Displays neuroprotective function in vitro and in vivo
-
Guillot-Sestier MV, Sunyach C, Druon C, Scarzello S, Checler F. The alpha-secretase-derived N-terminal product of cellular prion, N1: displays neuroprotective function in vitro and in vivo. J Biol Chem 2009; 284(51): 35973-35986.
-
(2009)
J Biol Chem
, vol.284
, Issue.51
, pp. 35973-35986
-
-
Guillot-Sestier, M.V.1
Sunyach, C.2
Druon, C.3
Scarzello, S.4
Checler, F.5
-
3
-
-
8344242220
-
Autophagy in health and disease: A double-edged sword
-
Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science 2004; 306(5698): 990-995.
-
(2004)
Science
, vol.306
, Issue.5698
, pp. 990-995
-
-
Shintani, T.1
Klionsky, D.J.2
-
4
-
-
79960111702
-
24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis
-
Yamanaka K, Saito Y, Yamamori T, Urano Y, Noguchi N. 24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis. J Biol Chem 2011; 286(28): 24666-24673.
-
(2011)
J Biol Chem
, vol.286
, Issue.28
, pp. 24666-24673
-
-
Yamanaka, K.1
Saito, Y.2
Yamamori, T.3
Urano, Y.4
Noguchi, N.5
-
5
-
-
0031282499
-
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells
-
Vercammen D, Vandenabeele P, Beyaert R, Declercq W, Fiers W. Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells. Cytokine 1997; 9(11): 801-808.
-
(1997)
Cytokine
, vol.9
, Issue.11
, pp. 801-808
-
-
Vercammen, D.1
Vandenabeele, P.2
Beyaert, R.3
Declercq, W.4
Fiers, W.5
-
7
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D, Beyaert R, Denecker G, et al. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 1998; 187(9): 1477-1485.
-
(1998)
J Exp Med
, vol.187
, Issue.9
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
-
8
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, Huang Z, Boyce M, et al. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 2005; 1(2): 112-119.
-
(2005)
Nat Chem Biol
, vol.1
, Issue.2
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
-
9
-
-
68149100523
-
NLRP3 (NALP3: Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and independent pathways
-
Willingham SB, Allen IC, Bergstralh DT, et al. NLRP3 (NALP3: Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and independent pathways. J Immunol 2009; 183(3): 2008-2015.
-
(2009)
J Immunol
, vol.183
, Issue.3
, pp. 2008-2015
-
-
Willingham, S.B.1
Allen, I.C.2
Bergstralh, D.T.3
-
10
-
-
66449133280
-
Phosphorylation-driven assembly of RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho Y, Challa S, Moquin D, et al. Phosphorylation-driven assembly of RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137(6): 1112-1123.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1112-1123
-
-
Cho, Y.1
Challa, S.2
Moquin, D.3
-
12
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines CP, Kaiser RA, Purcell NH, et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 2005; 434(7033): 658-662.
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
-
13
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa T, Shimizu S, Watanabe T, et al. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005; 434(7033): 652-658.
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
-
14
-
-
33644873010
-
Involvement of the mitochondrial ATP sensitive potassium channel in the neuroprotective effect of hyperbaric oxygenation after cerebral ischemia
-
Lou M, Chen Y, Ding M, Eschenfelder CC, Deuschl G. Involvement of the mitochondrial ATP sensitive potassium channel in the neuroprotective effect of hyperbaric oxygenation after cerebral ischemia. Brain Res Bull 2006; 69(2): 109-116.
-
(2006)
Brain Res Bull
, vol.69
, Issue.2
, pp. 109-116
-
-
Lou, M.1
Chen, Y.2
Ding, M.3
Eschenfelder, C.C.4
Deuschl, G.5
-
15
-
-
77955487488
-
The science of stroke: Mechanisms in search of treatments
-
Moskowitz MA, Lo EH, Iadecola C. The science of stroke: Mechanisms in search of treatments. Neuron 2010; 67(2): 181-198.
-
(2010)
Neuron
, vol.67
, Issue.2
, pp. 181-198
-
-
Moskowitz, M.A.1
Lo, E.H.2
Iadecola, C.3
-
16
-
-
57649181391
-
Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
-
Hitomi J, Christofferson DE, Ng A, et al. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008; 135(7): 1311-1323.
-
(2008)
Cell
, vol.135
, Issue.7
, pp. 1311-1323
-
-
Hitomi, J.1
Christofferson, D.E.2
Ng, A.3
-
17
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
Welz PS, Wullaert A, Vlantis K, et al. FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 2011; 477(7364): 330-334.
-
(2011)
Nature
, vol.477
, Issue.7364
, pp. 330-334
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
-
18
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser WJ, Upton JW, Long AB, et al. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 2011; 471(7338): 368-372.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
-
19
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'En IL, Tsau JS, Molkentin JD, Komatsu M, Hedrick SM. Mechanisms of necroptosis in T cells. J Exp Med 2011; 208(4): 633-641.
-
(2011)
J Exp Med
, vol.208
, Issue.4
, pp. 633-641
-
-
Ch'En, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
20
-
-
33646234026
-
Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1
-
Zheng L, Bidere N, Staudt D, et al. Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1. Mol Cell Biol 2006; 26(9): 3505-3513.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.9
, pp. 3505-3513
-
-
Zheng, L.1
Bidere, N.2
Staudt, D.3
-
21
-
-
33646034316
-
Activation of IKK by TNFa requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
-
Ea CK, Deng L, Xia ZP, Pineda G, Chen ZJ. Activation of IKK by TNFa requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol Cell 2006; 22(2): 245-257.
-
(2006)
Mol Cell
, vol.22
, Issue.2
, pp. 245-257
-
-
Ea, C.K.1
Deng, L.2
Xia, Z.P.3
Pineda, G.4
Chen, Z.J.5
-
22
-
-
33744951304
-
Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation
-
Li H, Kobayashi M, Blonska M, You Y, Lin X. Ubiquitination of RIP is required for tumor necrosis factor alpha-induced NF-kappaB activation. J Biol Chem 2006; 281(19): 13636-13643.
-
(2006)
J Biol Chem
, vol.281
, Issue.19
, pp. 13636-13643
-
-
Li, H.1
Kobayashi, M.2
Blonska, M.3
You, Y.4
Lin, X.5
-
23
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003; 114(2): 181-190.
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
24
-
-
70549107710
-
Mitochondrial cell death effectors
-
Brenner D, Mak TW. Mitochondrial cell death effectors. Curr Opin Cell Biol 2009; 21(6): 871-887.
-
(2009)
Curr Opin Cell Biol
, vol.21
, Issue.6
, pp. 871-887
-
-
Brenner, D.1
Mak, T.W.2
-
25
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
Chan FK, Shisler J, Bixby JG, et al. A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem 2003; 278(51): 51613-51621.
-
(2003)
J Biol Chem
, vol.278
, Issue.51
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
-
26
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, Challa S, Moquin D, et al. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009; 137(6): 1112-1123.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
-
27
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNFalpha
-
He S, Wang L, Miao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNFalpha. Cell 2009; 137(6): 1100-1111.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
-
28
-
-
67650812332
-
RIP3: An energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, Shao J, Lin J, et al. RIP3: an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009; 325(5938): 332-336.
-
(2009)
Science
, vol.325
, Issue.5938
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
-
29
-
-
52149095957
-
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice
-
Kang TB, Oh GS, Scandella E, et al. Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J Immunol 2008; 181(4): 2522-2532.
-
(2008)
J Immunol
, vol.181
, Issue.4
, pp. 2522-2532
-
-
Kang, T.B.1
Oh, G.S.2
Scandella, E.3
-
31
-
-
35548974703
-
Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
-
Wright A, Reiley WW, Chang M, et al. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev Cell 2007; 13(5): 705-716.
-
(2007)
Dev Cell
, vol.13
, Issue.5
, pp. 705-716
-
-
Wright, A.1
Reiley, W.W.2
Chang, M.3
-
32
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A, Dillon CP, Weinlich R, et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011; 471(7338): 363-367.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
-
33
-
-
77957105977
-
Molecular mechanisms of necroptosis: An ordered cellular explosion
-
Vandenabeele P, Galluzzi L, Vanden Berghe T, Kroemer G. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat Rev Mol Cell Biol 2010; 11(10): 700-714.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.10
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
Vanden Berghe, T.3
Kroemer, G.4
-
34
-
-
77951901715
-
Cell death in the pathogenesis of heart disease: Mechanisms and significance
-
Whelan RS, Kaplinskiy V, Kitsis RN. Cell death in the pathogenesis of heart disease: mechanisms and significance. Annu Rev Physiol 2010; 72: 19-44.
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 19-44
-
-
Whelan, R.S.1
Kaplinskiy, V.2
Kitsis, R.N.3
-
35
-
-
68649095201
-
Mitochondrial calcium and the permeability transition in cell death
-
Lemasters JJ, Theruvath TP, Zhong Z, Nieminen AL. Mitochondrial calcium and the permeability transition in cell death. Biochim Biophys Acta 2009; 1787(11): 1395-1401.
-
(2009)
Biochim Biophys Acta
, vol.1787
, Issue.11
, pp. 1395-1401
-
-
Lemasters, J.J.1
Theruvath, T.P.2
Zhong, Z.3
Nieminen, A.L.4
-
36
-
-
0033872030
-
Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition
-
Tafani M, Schneider TG, Pastorino JG, Farber JL. Cytochrome c-dependent activation of caspase-3 by tumor necrosis factor requires induction of the mitochondrial permeability transition. Am J Pathol 2000; 156(6): 2111-2121.
-
(2000)
Am J Pathol
, vol.156
, Issue.6
, pp. 2111-2121
-
-
Tafani, M.1
Schneider, T.G.2
Pastorino, J.G.3
Farber, J.L.4
-
37
-
-
0030069231
-
Control of apoptosis by the cellular ATP level
-
Richter C, Schweizer M, Cossarizza A, Franceschi C. Control of apoptosis by the cellular ATP level. FEBS Lett 1996; 378(2): 107-110.
-
(1996)
FEBS Lett
, vol.378
, Issue.2
, pp. 107-110
-
-
Richter, C.1
Schweizer, M.2
Cossarizza, A.3
Franceschi, C.4
-
38
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
Du H, Guo L, Fang F, et al. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med 2008; 14(10): 1097-1105.
-
(2008)
Nat Med
, vol.14
, Issue.10
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
-
39
-
-
0032504717
-
From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state
-
Ichas F, Mazat JP. From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim Biophys Acta 1998; 1366(1-2): 33-50.
-
(1998)
Biochim Biophys Acta
, vol.1366
, Issue.1-2
, pp. 33-50
-
-
Ichas, F.1
Mazat, J.P.2
-
40
-
-
0029810095
-
Mitochondrial dysfunction is a primary event in glutamate neurotoxicity
-
Schinder AF, Olson EC, Spitzer NC, Montal M. Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J Neurosci 1996; 16(19): 6125-6133.
-
(1996)
J Neurosci
, vol.16
, Issue.19
, pp. 6125-6133
-
-
Schinder, A.F.1
Olson, E.C.2
Spitzer, N.C.3
Montal, M.4
-
41
-
-
0029788243
-
Mitochondrial depolarization in glutamate-stimulated neurons: An early signal specific to excitotoxin exposure
-
White RJ, Reynolds IJ. Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. J Neurosci 1996; 16(18): 5688-5697.
-
(1996)
J Neurosci
, vol.16
, Issue.18
, pp. 5688-5697
-
-
White, R.J.1
Reynolds, I.J.2
-
42
-
-
38949167692
-
Oxidative stress and neurotoxicity
-
Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Tox 2008; 21(1): 172-188.
-
(2008)
Chem Res Tox
, vol.21
, Issue.1
, pp. 172-188
-
-
Sayre, L.M.1
Perry, G.2
Smith, M.A.3
-
43
-
-
0036884733
-
Pathogenesis of Parkinson's disease: Dopamine, vesicles and alpha-synuclein
-
Lotharius J, Brundin P. Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein. Nat Rev Neurosci 2002; 3(12): 932-942.
-
(2002)
Nat Rev Neurosci
, vol.3
, Issue.12
, pp. 932-942
-
-
Lotharius, J.1
Brundin, P.2
-
44
-
-
16444364285
-
p-Quinone mediates 6-hydroxydopamine-induced dopaminergic neuronal death and ferrous iron accelerates the conversion of p-quinone into melanin extracellularly
-
Izumi Y, Sawada H, Sakka N, et al. p-Quinone mediates 6-hydroxydopamine-induced dopaminergic neuronal death and ferrous iron accelerates the conversion of p-quinone into melanin extracellularly. J Neurosci Res 2005; 79(6): 849-860.
-
(2005)
J Neurosci Res
, vol.79
, Issue.6
, pp. 849-860
-
-
Izumi, Y.1
Sawada, H.2
Sakka, N.3
-
45
-
-
33748702290
-
Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease
-
McCoy MK, Martinez TN, Ruhn KA, et al. Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease. J Neurosci 2006; 26(37): 9365-9375.
-
(2006)
J Neurosci
, vol.26
, Issue.37
, pp. 9365-9375
-
-
McCoy, M.K.1
Martinez, T.N.2
Ruhn, K.A.3
-
46
-
-
0036719568
-
Mice deficient in TNFreceptors are protected against dopaminergic neurotoxicity: Implications for Parkinson's disease
-
Sriram K, Matheson JM, Benkovic SA, et al. Mice deficient in TNFreceptors are protected against dopaminergic neurotoxicity: Implications for Parkinson's disease. FASEB J 2002; 16(11): 1474-1476.
-
(2002)
FASEB J
, vol.16
, Issue.11
, pp. 1474-1476
-
-
Sriram, K.1
Matheson, J.M.2
Benkovic, S.A.3
-
47
-
-
34548316575
-
Deletion of tumor necrosis factor death receptor inhibits amyloid b generation and prevents learning and memory deficits in Alzheimer's mice
-
He P, Zhong Z, Lindholm K, et al. Deletion of tumor necrosis factor death receptor inhibits amyloid b generation and prevents learning and memory deficits in Alzheimer's mice. J Cell Biol 2007; 178(5): 829-841.
-
(2007)
J Cell Biol
, vol.178
, Issue.5
, pp. 829-841
-
-
He, P.1
Zhong, Z.2
Lindholm, K.3
-
48
-
-
75149118999
-
Neuroinflammation in Alzheimer's disease and mild cognitive impairment: A field in its infancy
-
McGeer EG, McGeer PL. Neuroinflammation in Alzheimer's disease and mild cognitive impairment: a field in its infancy. J Alzheimers Dis 2010; 19(1): 355-361.
-
(2010)
J Alzheimers Dis
, vol.19
, Issue.1
, pp. 355-361
-
-
McGeer, E.G.1
McGeer, P.L.2
-
49
-
-
18344414746
-
The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
-
Huang X, Atwood CS, Hartshorn MA, et al. The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction. Biochemistry 1999; 38(24): 7609-7916.
-
(1999)
Biochemistry
, vol.38
, Issue.24
, pp. 7609-7916
-
-
Huang, X.1
Atwood, C.S.2
Hartshorn, M.A.3
-
50
-
-
35348981740
-
Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide
-
Hayashi T, Shishido N, Nakayama K, et al. Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide. Free Radic Biol Med 2007; 43(11): 1552-1559.
-
(2007)
Free Radic Biol Med
, vol.43
, Issue.11
, pp. 1552-1559
-
-
Hayashi, T.1
Shishido, N.2
Nakayama, K.3
-
51
-
-
35948936850
-
Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron
-
Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Hayashi Y, Nakayama K, Hayashi T, et al. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry 2007; 46(44): 12737-12743.
-
(2007)
Biochemistry
, vol.46
, Issue.44
, pp. 12737-12743
-
-
Nakamura, M.1
Shishido, N.2
Nunomura, A.3
Smith, M.A.4
Perry, G.5
Hayashi, Y.6
Nakayama, K.7
Hayashi, T.8
-
52
-
-
33747203455
-
Tumor necrosis factor alpha and interleukin 10 promoter region polymorphisms and risk of late-onset Alzheimer disease
-
Ramos EM, Lin MT, Larson EB, et al. Tumor necrosis factor alpha and interleukin 10 promoter region polymorphisms and risk of late-onset Alzheimer disease. Arch Neurol 2006; 63(8): 1165-1169.
-
(2006)
Arch Neurol
, vol.63
, Issue.8
, pp. 1165-1169
-
-
Ramos, E.M.1
Lin, M.T.2
Larson, E.B.3
-
53
-
-
0842304128
-
Association between tumor necrosis factor-α promoter polymorphism and Alzheimer's disease
-
Ma SL, Tang NLS. Association between tumor necrosis factor-α promoter polymorphism and Alzheimer's disease. Neurology 2004; 62(2): 307-309.
-
(2004)
Neurology
, vol.62
, Issue.2
, pp. 307-309
-
-
Ma, S.L.1
Tang, N.L.S.2
-
54
-
-
0032717067
-
Redox regulation of TNF signaling
-
Goossens V, De Vos K, Vercammen D, et al. Redox regulation of TNF signaling. Biofactors 1999; 10(2-3): 145-156.
-
(1999)
Biofactors
, vol.10
, Issue.2-3
, pp. 145-156
-
-
Goossens, V.1
de Vos, K.2
Vercammen, D.3
-
55
-
-
1642299768
-
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation
-
Lin Y, Choksi S, Shen HM, et al. Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. J Biol Chem 2004; 279(11): 10822-10828.
-
(2004)
J Biol Chem
, vol.279
, Issue.11
, pp. 10822-10828
-
-
Lin, Y.1
Choksi, S.2
Shen, H.M.3
-
56
-
-
84859467770
-
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
-
Zhao J, Jitkaew S, Cai Z, et al. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci USA 2012; 109(14): 5322-5327.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.14
, pp. 5322-5327
-
-
Zhao, J.1
Jitkaew, S.2
Cai, Z.3
-
57
-
-
84862909353
-
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
-
Wang Z, Jiang H, Chen S, Du F, Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012; 148(1-2): 228-243.
-
(2012)
Cell
, vol.148
, Issue.1-2
, pp. 228-243
-
-
Wang, Z.1
Jiang, H.2
Chen, S.3
Du, F.4
Wang, X.5
-
58
-
-
21244446551
-
Properties of the permeability transition pore in mitochondria devoid of cyclophilin D
-
Basso E, Fante L, Fowlkes J, et al. Properties of the permeability transition pore in mitochondria devoid of cyclophilin D. J Biol Chem 2005; 280(19): 18558-18561.
-
(2005)
J Biol Chem
, vol.280
, Issue.19
, pp. 18558-18561
-
-
Basso, E.1
Fante, L.2
Fowlkes, J.3
-
59
-
-
24744460273
-
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
-
Schinzel AC, Takeuchi O, Huang Z, et al. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci USA 2005; 102(34): 12005-12010.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.34
, pp. 12005-12010
-
-
Schinzel, A.C.1
Takeuchi, O.2
Huang, Z.3
-
61
-
-
0035399637
-
Programmed cell death of developing mammalian neurons after genetic deletion of caspases
-
Oppenheim RW, Flavell RA, Vinsant S, et al. Programmed cell death of developing mammalian neurons after genetic deletion of caspases. J Neurosci 2001; 21(13): 4752-4760.
-
(2001)
J Neurosci
, vol.21
, Issue.13
, pp. 4752-4760
-
-
Oppenheim, R.W.1
Flavell, R.A.2
Vinsant, S.3
-
62
-
-
33744805129
-
Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways
-
West T, Atzeva M, Holtzman DM. Caspase-3 deficiency during development increases vulnerability to hypoxic-ischemic injury through caspase-3-independent pathways. Neurobiol Dis 2006; 22(3): 523-537.
-
(2006)
Neurobiol Dis
, vol.22
, Issue.3
, pp. 523-537
-
-
West, T.1
Atzeva, M.2
Holtzman, D.M.3
-
63
-
-
33645640921
-
Cell death in pancreatitis: Caspases protect from necrotizing pancreatitis
-
Mareninova OA, Sung KF, Hong P, et al. Cell death in pancreatitis: caspases protect from necrotizing pancreatitis. J Biol Chem 2006; 281(6): 3370-3381.
-
(2006)
J Biol Chem
, vol.281
, Issue.6
, pp. 3370-3381
-
-
Mareninova, O.A.1
Sung, K.F.2
Hong, P.3
-
64
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A, Hitomi J, Germscheid M, et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 2008; 4(5): 313-321.
-
(2008)
Nat Chem Biol
, vol.4
, Issue.5
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
-
65
-
-
83155192804
-
TNF induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members
-
Vanlangenakker N, Bertrand MJ, Bogaert P, Vandenabeele P, Vanden Berghe T. TNF induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members. Cell Death Dis 2011; 2: e230.
-
(2011)
Cell Death Dis
, vol.2
-
-
Vanlangenakker, N.1
Bertrand, M.J.2
Bogaert, P.3
Vandenabeele, P.4
Vanden Berghe, T.5
-
66
-
-
34247485841
-
Role of the mitochondrial membrane permeability transition in cell death
-
Tsujimoto Y, Shimizu S. Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 2007; 12(5): 835-840.
-
(2007)
Apoptosis
, vol.12
, Issue.5
, pp. 835-840
-
-
Tsujimoto, Y.1
Shimizu, S.2
-
67
-
-
67349117275
-
What is the mitochondrial permeability transition pore?
-
Halestrap AP. What is the mitochondrial permeability transition pore? J Mol Cell Cardiol 2009; 46(6): 821-831.
-
(2009)
J Mol Cell Cardiol
, vol.46
, Issue.6
, pp. 821-831
-
-
Halestrap, A.P.1
-
68
-
-
79959504861
-
An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons
-
Martin LJ. An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons. Toxicol Pathol 2011; 39(1): 220-233.
-
(2011)
Toxicol Pathol
, vol.39
, Issue.1
, pp. 220-233
-
-
Martin, L.J.1
-
69
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell MA, Perez-Jimenez E, Oberst A, et al. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 2011; 13(12): 1437-1442.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.12
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
-
70
-
-
77649259009
-
Loss of the tumor suppressor CYLD enhances Wnt/b-catenin signaling through K63-linked ubiquitination of Dvl
-
Tauriello DV, Haegebarth A, Kuper I, et al. Loss of the tumor suppressor CYLD enhances Wnt/b-catenin signaling through K63-linked ubiquitination of Dvl. Mol Cell 2010; 37(5): 607-619.
-
(2010)
Mol Cell
, vol.37
, Issue.5
, pp. 607-619
-
-
Tauriello, D.V.1
Haegebarth, A.2
Kuper, I.3
-
71
-
-
78649901091
-
Alternative cell death mechanisms in development and beyond
-
Yuan J, Kroemer G. Alternative cell death mechanisms in development and beyond. Genes Dev 2010; 24(23): 2592-2602.
-
(2010)
Genes Dev
, vol.24
, Issue.23
, pp. 2592-2602
-
-
Yuan, J.1
Kroemer, G.2
-
72
-
-
0029100890
-
Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis
-
Watson AJ, Askew JN, Benson RS. Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis. Gastroenterology 1995; 109(2): 472-482.
-
(1995)
Gastroenterology
, vol.109
, Issue.2
, pp. 472-482
-
-
Watson, A.J.1
Askew, J.N.2
Benson, R.S.3
-
73
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, et al. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 2002; 297(5579): 259-263.
-
(2002)
Science
, vol.297
, Issue.5579
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
-
74
-
-
0030832874
-
Ischemic brain injury is mediated by the activation of poly(ADP-ribose) polymerase
-
Endres M, Wang ZQ, Namura S, Waeber C, Moskowitz MA. Ischemic brain injury is mediated by the activation of poly(ADP-ribose) polymerase. J Cereb Blood Flow Metab 1997; 17(11): 1143-1151.
-
(1997)
J Cereb Blood Flow Metab
, vol.17
, Issue.11
, pp. 1143-1151
-
-
Endres, M.1
Wang, Z.Q.2
Namura, S.3
Waeber, C.4
Moskowitz, M.A.5
-
75
-
-
65149097030
-
Interleukin-33 - cytokine of dual function or novel alarmin?
-
Haraldsen G, Balogh J, Pollheimer J, Sponheim J, Kuchler AM. Interleukin-33 - cytokine of dual function or novel alarmin? Trends Immunol 2009; 30(5): 227-33.
-
(2009)
Trends Immunol
, vol.30
, Issue.5
, pp. 227-233
-
-
Haraldsen, G.1
Balogh, J.2
Pollheimer, J.3
Sponheim, J.4
Kuchler, A.M.5
-
76
-
-
76349101890
-
High-mobility group protein box-1 and its relevance to cerebral ischemia
-
Yang QW, Wang JZ, Li JC, et al. High-mobility group protein box-1 and its relevance to cerebral ischemia. J Cereb Blood Flow Metab 2010; 30(2): 243-254.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, Issue.2
, pp. 243-254
-
-
Yang, Q.W.1
Wang, J.Z.2
Li, J.C.3
-
77
-
-
34848917621
-
High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo
-
Faraco G, Fossati S, Bianchi ME, et al. High mobility group box 1 protein is released by neural cells upon different stresses and worsens ischemic neurodegeneration in vitro and in vivo. J Neurochem 2007; 103(2): 590-603.
-
(2007)
J Neurochem
, vol.103
, Issue.2
, pp. 590-603
-
-
Faraco, G.1
Fossati, S.2
Bianchi, M.E.3
-
78
-
-
33847644971
-
The inflammatory response in stroke
-
Wang Q, Tang XN, Yenari MA. The inflammatory response in stroke. J Neuroimmunol 2007; 184(1-2): 53-68.
-
(2007)
J Neuroimmunol
, vol.184
, Issue.1-2
, pp. 53-68
-
-
Wang, Q.1
Tang, X.N.2
Yenari, M.A.3
-
79
-
-
0033512004
-
Inflammatory mediators and stroke: New opportunities for novel therapeutics
-
Barone FC, Feuerstein GZ. Inflammatory mediators and stroke: New opportunities for novel therapeutics. J Cereb Blood Flow Metab 1999; 19(8): 819-834.
-
(1999)
J Cereb Blood Flow Metab
, vol.19
, Issue.8
, pp. 819-834
-
-
Barone, F.C.1
Feuerstein, G.Z.2
-
80
-
-
0035478029
-
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia
-
Asahi M, Wang X, Mori T, et al. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci 2001; 21(19): 7724-7732.
-
(2001)
J Neurosci
, vol.21
, Issue.19
, pp. 7724-7732
-
-
Asahi, M.1
Wang, X.2
Mori, T.3
-
81
-
-
0033638508
-
Role for matrix metalloproteinase 9 after focal cerebral ischemia: Effects of gene knockout and enzyme inhibition with bb-94
-
Asahi M, Asahi K, Jung JC, et al. Role for matrix metalloproteinase 9 after focal cerebral ischemia: Effects of gene knockout and enzyme inhibition with bb-94. J Cereb Blood Flow Metab 2000; 20(12): 1681-1689.
-
(2000)
J Cereb Blood Flow Metab
, vol.20
, Issue.12
, pp. 1681-1689
-
-
Asahi, M.1
Asahi, K.2
Jung, J.C.3
-
82
-
-
0036737795
-
Matrix metalloproteinases in neuroinflammation
-
Rosenberg GA. Matrix metalloproteinases in neuroinflammation. Glia 2002; 39(3): 279-291.
-
(2002)
Glia
, vol.39
, Issue.3
, pp. 279-291
-
-
Rosenberg, G.A.1
-
83
-
-
33846303121
-
Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood-brain barrier opening in rodents: Differences in response based on strains and solvents
-
Rosenberg GA, Estrada EY, Mobashery S. Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood-brain barrier opening in rodents: Differences in response based on strains and solvents. Brain Res 2007; 1133(1): 186-192.
-
(2007)
Brain Res
, vol.1133
, Issue.1
, pp. 186-192
-
-
Rosenberg, G.A.1
Estrada, E.Y.2
Mobashery, S.3
-
84
-
-
77956405894
-
High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia
-
Qiu J, Xu J, Zheng Y, et al. High-mobility group box 1 promotes metalloproteinase-9 upregulation through Toll-like receptor 4 after cerebral ischemia. Stroke 2010; 41(9): 2077-2082.
-
(2010)
Stroke
, vol.41
, Issue.9
, pp. 2077-2082
-
-
Qiu, J.1
Xu, J.2
Zheng, Y.3
-
85
-
-
84984763363
-
Mechanisms, challenges and opportunities in stroke
-
Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 2003; 4(5): 399-415.
-
(2003)
Nat Rev Neurosci
, vol.4
, Issue.5
, pp. 399-415
-
-
Lo, E.H.1
Dalkara, T.2
Moskowitz, M.A.3
-
86
-
-
33745788420
-
Hmgb1: A novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain
-
Kim JB, Sig Choi J, Yu YM, et al. Hmgb1: a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain. J Neurosci 2006; 26(24): 6413-6421.
-
(2006)
J Neurosci
, vol.26
, Issue.24
, pp. 6413-6421
-
-
Kim, J.B.1
Sig Choi, J.2
Yu, Y.M.3
-
87
-
-
36849076615
-
Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats
-
Liu K, Mori S, Takahashi HK, et al. Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats. FASEB J 2007; 21(14): 3904-3916.
-
(2007)
FASEB J
, vol.21
, Issue.14
, pp. 3904-3916
-
-
Liu, K.1
Mori, S.2
Takahashi, H.K.3
-
88
-
-
42549139329
-
Early release of hmgb-1 from neurons after the onset of brain ischemia
-
Qiu J, Nishimura M, Wang Y, Sims JR, et al. Early release of hmgb-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab 2008; 28(5): 927-938.
-
(2008)
J Cereb Blood Flow Metab
, vol.28
, Issue.5
, pp. 927-938
-
-
Qiu, J.1
Nishimura, M.2
Wang, Y.3
Sims, J.R.4
-
89
-
-
20244373939
-
The nuclear factor hmgb1 mediates hepatic injury after murine liver ischemiareperfusion
-
Tsung A, Sahai R, Tanaka H, et al. The nuclear factor hmgb1 mediates hepatic injury after murine liver ischemiareperfusion. J Exp Med 2005; 201(7): 1135-1143.
-
(2005)
J Exp Med
, vol.201
, Issue.7
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
-
90
-
-
33845897894
-
Pivotal advances: High-mobility group box 1 protein - a cytokine with a role in cardiac repair
-
Germani A, Limana F, Capogrossi MC. Pivotal advances: High-mobility group box 1 protein - a cytokine with a role in cardiac repair. J Leukoc Biol 2007; 81(1): 41-45.
-
(2007)
J Leukoc Biol
, vol.81
, Issue.1
, pp. 41-45
-
-
Germani, A.1
Limana, F.2
Capogrossi, M.C.3
-
91
-
-
48249109117
-
Effect of cyclosporine on reperfusion injury in acute myocardial infarction
-
Piot C, Croisille P, Staat P. Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med 2008; 359(5): 473-481.
-
(2008)
N Engl J Med
, vol.359
, Issue.5
, pp. 473-481
-
-
Piot, C.1
Croisille, P.2
Staat, P.3
-
92
-
-
42649130014
-
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
-
Lo SC, Hannink M. PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria. Exp Cell Res 2008; 314(8): 1789-1803.
-
(2008)
Exp Cell Res
, vol.314
, Issue.8
, pp. 1789-1803
-
-
Lo, S.C.1
Hannink, M.2
-
93
-
-
36248933743
-
Necrostatin-1 protects against glutamate- induced glutathione depletion and caspase-independent cell death in HT-22 cells
-
Xu X, Chua CC, Kong J, et al. Necrostatin-1 protects against glutamate- induced glutathione depletion and caspase-independent cell death in HT-22 cells. J Neurochem 2007; 103(5): 2004-2014.
-
(2007)
J Neurochem
, vol.103
, Issue.5
, pp. 2004-2014
-
-
Xu, X.1
Chua, C.C.2
Kong, J.3
-
94
-
-
84954358195
-
Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons
-
Li Y, Yang X, Ma C, Qiao J, Zhang C. Necroptosis contributes to the NMDA-induced excitotoxicity in rat's cultured cortical neurons. Neurosci Lett 2008; 447(2-3): 120-123.
-
(2008)
Neurosci Lett
, vol.447
, Issue.2-3
, pp. 120-123
-
-
Li, Y.1
Yang, X.2
Ma, C.3
Qiao, J.4
Zhang, C.5
-
95
-
-
78650911946
-
Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI
-
Northington FJ, Chavez-Valdez R, Graham EM, et al. Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI. J Cereb Blood Flow Metab 2010; 31(1): 178-189.
-
(2010)
J Cereb Blood Flow Metab
, vol.31
, Issue.1
, pp. 178-189
-
-
Northington, F.J.1
Chavez-Valdez, R.2
Graham, E.M.3
-
96
-
-
34548564715
-
Necrostatin: A potentially novel cardioprotective agent?
-
Smith CC, Davidson SM, Lim SY, et al. Necrostatin: a potentially novel cardioprotective agent? Cardiovasc Drugs Ther 2007; 21(4): 227-233.
-
(2007)
Cardiovasc Drugs Ther
, vol.21
, Issue.4
, pp. 227-233
-
-
Smith, C.C.1
Davidson, S.M.2
Lim, S.Y.3
-
97
-
-
77956619262
-
Synergistic protective effects of humanin and necrostatin-1 on hypoxia and iscemia/reperfusion injury
-
Xu X, Chua KW, Chua CC, et al. Synergistic protective effects of humanin and necrostatin-1 on hypoxia and iscemia/reperfusion injury. Brain Res 2010; 1355: 189-194.
-
(2010)
Brain Res
, vol.1355
, pp. 189-194
-
-
Xu, X.1
Chua, K.W.2
Chua, C.C.3
-
98
-
-
77952059124
-
Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia reperfusion injury model
-
Rosenbaum DM, Degterev A, David J, et al. Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia reperfusion injury model. J Neurosci Res 2010; 88(7) 1569-1576.
-
(2010)
J Neurosci Res
, vol.88
, Issue.7
, pp. 1569-1576
-
-
Rosenbaum, D.M.1
Degterev, A.2
David, J.3
-
99
-
-
33747626309
-
Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Implication for the regulatory role of protein kinase C
-
Byun HS, Park KA, Won M, et al. Phorbol 12-myristate 13-acetate protects against tumor necrosis factor (TNF)-induced necrotic cell death by modulating the recruitment of TNF receptor 1-associated death domain and receptor-interacting protein into the TNF receptor 1 signaling complex: Implication for the regulatory role of protein kinase C. Mol Pharmacol 2006; 70(3): 1099-1108.
-
(2006)
Mol Pharmacol
, vol.70
, Issue.3
, pp. 1099-1108
-
-
Byun, H.S.1
Park, K.A.2
Won, M.3
-
100
-
-
35848945069
-
Structure-activity relationship study of [1: 2: 3]thiadiazole necroptosis inhibitors
-
Teng X, Keys H, Jeevanandam A, et al. Structure-activity relationship study of [1: 2: 3]thiadiazole necroptosis inhibitors. Bioorg Med Chem Lett 2007; 17(24): 6836-6840.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, Issue.24
, pp. 6836-6840
-
-
Teng, X.1
Keys, H.2
Jeevanandam, A.3
-
101
-
-
44149110896
-
Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors
-
Teng X, Keys H, Yuan J, Degterev A, Cuny GD. Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors. Bioorg Med Chem Lett 2008; 18(11): 3219-3223.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, Issue.11
, pp. 3219-3223
-
-
Teng, X.1
Keys, H.2
Yuan, J.3
Degterev, A.4
Cuny, G.D.5
-
102
-
-
34247264421
-
Structure-activity relationship study of tricyclic necroptosis inhibitors
-
Jagtap PG, Degterev A, Choi S, et al. Structure-activity relationship study of tricyclic necroptosis inhibitors. J Med Chem 2007; 50(8): 1886-1895.
-
(2007)
J Med Chem
, vol.50
, Issue.8
, pp. 1886-1895
-
-
Jagtap, P.G.1
Degterev, A.2
Choi, S.3
-
103
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
-
Pyo JO, Jang MH, Kwon YK, et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 2005; 280(21): 20722-20729.
-
(2005)
J Biol Chem
, vol.280
, Issue.21
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
-
104
-
-
0029026548
-
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
-
Chinnaiyan AM, O'Rourke K, Tewari M, Dixit VM. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell 1995; 81(4): 505-512.
-
(1995)
Cell
, vol.81
, Issue.4
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
105
-
-
14844310233
-
Selective inactivation of a Fas-associated death domain protein (FADD)- dependent apoptosis and autophagy pathway in immortal epithelial cells
-
Thorburn J, Moore F, Rao A, et al. Selective inactivation of a Fas-associated death domain protein (FADD)- dependent apoptosis and autophagy pathway in immortal epithelial cells. Mol Biol Cell 2005; 16(3): 1189-1199.
-
(2005)
Mol Biol Cell
, vol.16
, Issue.3
, pp. 1189-1199
-
-
Thorburn, J.1
Moore, F.2
Rao, A.3
-
106
-
-
75149167546
-
Beclin 1 modulates the anti-apoptotic activity of Bcl-2: Insights from a pathogen infection system
-
Vazquez CL, Colombo MI. Beclin 1 modulates the anti-apoptotic activity of Bcl-2: insights from a pathogen infection system. Autophagy 2010; 6(1): 177-178.
-
(2010)
Autophagy
, vol.6
, Issue.1
, pp. 177-178
-
-
Vazquez, C.L.1
Colombo, M.I.2
-
107
-
-
0001488499
-
Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2- interacting protein
-
Liang XH, Kleeman LK, Jiang HH, et al. Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2- interacting protein. J Virol 1998; 72(11): 8586-8596.
-
(1998)
J Virol
, vol.72
, Issue.11
, pp. 8586-8596
-
-
Liang, X.H.1
Kleeman, L.K.2
Jiang, H.H.3
-
108
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, et al. Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 2005; 122(6): 927-939.
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
-
109
-
-
0019968818
-
Labelling of dying neurones by peroxidase injected intravascularly in chick embryos
-
Clarke PG. Labelling of dying neurones by peroxidase injected intravascularly in chick embryos. Neurosci Lett 1982; 30(3): 223-228.
-
(1982)
Neurosci Lett
, vol.30
, Issue.3
, pp. 223-228
-
-
Clarke, P.G.1
-
110
-
-
0021133597
-
Identical populations of phagocytes and dying neurons revealed by intravascularly injected horseradish peroxidase, and by endogenous glutaraldehyde-resistant acid phosphatase, in the brains of chick embryos
-
Clarke PG. Identical populations of phagocytes and dying neurons revealed by intravascularly injected horseradish peroxidase, and by endogenous glutaraldehyde-resistant acid phosphatase, in the brains of chick embryos. Histochem J 1984; 16(9): 955-969.
-
(1984)
Histochem J
, vol.16
, Issue.9
, pp. 955-969
-
-
Clarke, P.G.1
-
111
-
-
0042915885
-
Kainate-induced endocytosis in retinal amacrine cells
-
Borsello T, Bressoud R, Mottier V, et al. Kainate-induced endocytosis in retinal amacrine cells. J Comp Neurol 2003; 465(2): 286-295.
-
(2003)
J Comp Neurol
, vol.465
, Issue.2
, pp. 286-295
-
-
Borsello, T.1
Bressoud, R.2
Mottier, V.3
-
112
-
-
2642553881
-
Regulation of an ATG7- beclin 1 program of autophagic cell death by caspase-8
-
Yu L, Alva A, Su H, et al. Regulation of an ATG7- beclin 1 program of autophagic cell death by caspase-8. Science 2004; 304(5676): 1500-1502.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1500-1502
-
-
Yu, L.1
Alva, A.2
Su, H.3
-
113
-
-
23844483152
-
The apoptosis/autophagy paradox: Autophagic vacuolization before apoptotic death
-
Gonzalez-Polo RA, Boya P, Pauleau AL, et al. The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death. J Cell Sci 2005; 118(Pt 14) 3091-3102.
-
(2005)
J Cell Sci
, vol.118
, Issue.PART 14
, pp. 3091-3102
-
-
Gonzalez-Polo, R.A.1
Boya, P.2
Pauleau, A.L.3
-
114
-
-
33645512801
-
Bcl-2 inhibition of autophagy: A new route to cancer?
-
Pattingre S, Levine B. Bcl-2 inhibition of autophagy: a new route to cancer? Cancer Res 2006; 66(6): 2885-2888.
-
(2006)
Cancer Res
, vol.66
, Issue.6
, pp. 2885-2888
-
-
Pattingre, S.1
Levine, B.2
-
115
-
-
33749162486
-
Calpain mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, Perozzo R, Schmid I, et al. Calpain mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 2006; 8(10): 1124-1132.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.10
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
-
116
-
-
72949091020
-
p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms
-
Wang Y, Dong XX, Cao Y, et al. p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms. Eur J Neurosci 2009; 30(12): 2258-2270.
-
(2009)
Eur J Neurosci
, vol.30
, Issue.12
, pp. 2258-2270
-
-
Wang, Y.1
Dong, X.X.2
Cao, Y.3
-
117
-
-
0141884305
-
Diversity in the mechanisms of neuronal cell death
-
Yuan J, Lipinski M, Degterev A. Diversity in the mechanisms of neuronal cell death. Neuron 2003; 40(2): 401-413.
-
(2003)
Neuron
, vol.40
, Issue.2
, pp. 401-413
-
-
Yuan, J.1
Lipinski, M.2
Degterev, A.3
-
118
-
-
34447643958
-
Toll-like receptor 4 is a sensor for autophagy associated with innate immunity
-
Xu Y, Jagannath C, Liu XD, et al. Toll-like receptor 4 is a sensor for autophagy associated with innate immunity. Immunity 2007; 27(1): 134-144.
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 134-144
-
-
Xu, Y.1
Jagannath, C.2
Liu, X.D.3
-
119
-
-
0033153320
-
The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation
-
Sanz L, Sanchez P, Lallena MJ, Diaz-Meco MT, Moscat J. The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. EMBO J 1999; 18(11): 3044-3053.
-
(1999)
EMBO J
, vol.18
, Issue.11
, pp. 3044-3053
-
-
Sanz, L.1
Sanchez, P.2
Lallena, M.J.3
Diaz-Meco, M.T.4
Moscat, J.5
-
120
-
-
66449114033
-
p62 at the crossroads of autophagy, apoptosis, and cancer
-
Moscat J, Diaz-Meco MT. p62 at the crossroads of autophagy, apoptosis, and cancer. Cell 2009; 137(6): 1001-1004.
-
(2009)
Cell
, vol.137
, Issue.6
, pp. 1001-1004
-
-
Moscat, J.1
Diaz-Meco, M.T.2
-
121
-
-
55949083821
-
FADD and caspase-8 control the outcome of autophagic signaling in T cells
-
Bell BD, Leverrier S, Weist BM, et al. FADD and caspase-8 control the outcome of autophagic signaling in T cells. Proc Natl Acad Sci USA 2008; 105(43): 16677-16682.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.43
, pp. 16677-16682
-
-
Bell, B.D.1
Leverrier, S.2
Weist, B.M.3
-
122
-
-
56249132503
-
Antigen-mediated T cell expansion regulated by parallel pathways of death
-
Ch'En IL, Beisner DR, Degterev A, et al. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proc Natl Acad Sci USA 2008; 105(45): 17463-17468.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.45
, pp. 17463-17468
-
-
Ch'En, I.L.1
Beisner, D.R.2
Degterev, A.3
-
123
-
-
38049123578
-
Autophagy promotes necrosis in poptosis-deficient cells in response to ER stress
-
Ullman E, Fan Y, Stawowczyk M, et al. Autophagy promotes necrosis in poptosis-deficient cells in response to ER stress. Cell Death Differ 2008; 15(2): 422-425.
-
(2008)
Cell Death Differ
, vol.15
, Issue.2
, pp. 422-425
-
-
Ullman, E.1
Fan, Y.2
Stawowczyk, M.3
-
124
-
-
22344444616
-
Does autophagy contribute to cell death?
-
Debnath J, Baehrecke EH, Kroemer G. Does autophagy contribute to cell death? Autophagy 2005; 1(2): 66-74.
-
(2005)
Autophagy
, vol.1
, Issue.2
, pp. 66-74
-
-
Debnath, J.1
Baehrecke, E.H.2
Kroemer, G.3
-
125
-
-
20344387475
-
Autophagy: Dual roles in life and death?
-
Baehrecke EH. Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 2005; 6(6): 505-510.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, Issue.6
, pp. 505-510
-
-
Baehrecke, E.H.1
-
126
-
-
84255191988
-
Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction
-
Xiao J, Moon M, Yan L, et al. Cellular FLICE-inhibitory protein protects against cardiac remodelling after myocardial infarction. Basic Res Cardiol 2012; 107(1): 239.
-
(2012)
Basic Res Cardiol
, vol.107
, Issue.1
, pp. 239
-
-
Xiao, J.1
Moon, M.2
Yan, L.3
-
127
-
-
81355149658
-
Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo
-
Schattenberg JM, Zimmermann T, Wörns M, et al. Ablation of c-FLIP in hepatocytes enhances death-receptor mediated apoptosis and toxic liver injury in vivo. J Hepatol 2011; 55(6): 1272-1280.
-
(2011)
J Hepatol
, vol.55
, Issue.6
, pp. 1272-1280
-
-
Schattenberg, J.M.1
Zimmermann, T.2
Wörns, M.3
-
128
-
-
32544434769
-
Neuroprotective effect of A20 on TNF-induced postischemic apoptosis
-
Yu L, Miao H, Hou Y, Zhang B, Guo L. Neuroprotective effect of A20 on TNF-induced postischemic apoptosis. Neurochem Res 2006; 31(1): 21-32.
-
(2006)
Neurochem Res
, vol.31
, Issue.1
, pp. 21-32
-
-
Yu, L.1
Miao, H.2
Hou, Y.3
Zhang, B.4
Guo, L.5
-
129
-
-
65549085701
-
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
-
Jin Z, Li Y, Pitti R, et al. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 2009; 137(4): 721-735.
-
(2009)
Cell
, vol.137
, Issue.4
, pp. 721-735
-
-
Jin, Z.1
Li, Y.2
Pitti, R.3
-
130
-
-
37849036487
-
Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells
-
Nakajima A, Kojima Y, Nakayama M, et al. Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells. Oncogene 2008; 27(1): 76-84.
-
(2008)
Oncogene
, vol.27
, Issue.1
, pp. 76-84
-
-
Nakajima, A.1
Kojima, Y.2
Nakayama, M.3
-
131
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A, Dillon CP, Weinlich R, et al. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011; 471(7338): 363-367.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
-
132
-
-
17144404884
-
Functional dichotomy of A20 in apoptotic and necrotic cell death
-
Storz P, Döppler H, Ferran C, Grey ST, Toker A. Functional dichotomy of A20 in apoptotic and necrotic cell death. Biochem J 2005; 387(Pt 1): 47-55.
-
(2005)
Biochem J
, vol.387
, Issue.PART 1
, pp. 47-55
-
-
Storz, P.1
Döppler, H.2
Ferran, C.3
Grey, S.T.4
Toker, A.5
|