Anti-high mobility group box 1 monoclonal antibody ameliorates brain infarction induced by transient ischemia in rats

FASEB Journal

Volumn 21, Issue 14, 2007, Pages 3904-3916

  Liu, Keyue ^a   Mori, Shuji ^a,d   Takahashi, Hideo K ^a   Tomono, Yasuko ^b   Wake, Hidenori ^a   Kanke, Toru ^a   Sato, Yasuharu ^a   Hiraga, Norihito ^c   Adachi, Naoto ^c   Yoshino, Tadashi ^a   Nishibori, Masahiro ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b Shigei Medical Research Institute   (Japan)

^c EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d SHUJITSU UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; Inducible nitric oxide synthase; Inflammation; Matrix metalloproteinase; Target therapy

Indexed keywords

GELATINASE B; HIGH MOBILITY GROUP B1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN INFARCTION; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOCOMOTION; MALE; MEMBRANE PERMEABILITY; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; REPERFUSION INJURY;

ANIMALS; ANTIBODIES, MONOCLONAL; BRAIN INFARCTION; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; ENCEPHALITIS; HMGB1 PROTEIN; ISCHEMIC ATTACK, TRANSIENT; MALE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

RATTUS;

EID: 36849076615     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8770com     Document Type: Article

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