-
1
-
-
35649007879
-
A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila
-
Arama E., Bader M., Rieckhof G.E., and Steller H. A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila. PLoS Biol. 5 (2007) e251
-
(2007)
PLoS Biol.
, vol.5
-
-
Arama, E.1
Bader, M.2
Rieckhof, G.E.3
Steller, H.4
-
2
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
Ashkenazi A. Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat. Rev. Cancer 2 (2002) 420-430
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 420-430
-
-
Ashkenazi, A.1
-
3
-
-
0032575714
-
Death receptors: signaling and modulation
-
Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Science 281 (1998) 1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
4
-
-
33745928465
-
Death-receptor activation halts clathrin-dependent endocytosis
-
Austin C.D., Lawrence D.A., Peden A.A., Varfolomeev E.E., Totpal K., De Maziere A.M., Klumperman J., Arnott D., Pham V., Scheller R.H., and Ashkenazi A. Death-receptor activation halts clathrin-dependent endocytosis. Proc. Natl. Acad. Sci. USA 103 (2006) 10283-10288
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10283-10288
-
-
Austin, C.D.1
Lawrence, D.A.2
Peden, A.A.3
Varfolomeev, E.E.4
Totpal, K.5
De Maziere, A.M.6
Klumperman, J.7
Arnott, D.8
Pham, V.9
Scheller, R.H.10
Ashkenazi, A.11
-
5
-
-
33845501864
-
Apoptosome: a platform for the activation of initiator caspases
-
Bao Q., and Shi Y. Apoptosome: a platform for the activation of initiator caspases. Cell Death Differ. 14 (2007) 56-65
-
(2007)
Cell Death Differ.
, vol.14
, pp. 56-65
-
-
Bao, Q.1
Shi, Y.2
-
6
-
-
27944504351
-
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
Bjorkoy G., Lamark T., Brech A., Outzen H., Perander M., Overvatn A., Stenmark H., and Johansen T. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell Biol. 171 (2005) 603-614
-
(2005)
J. Cell Biol.
, vol.171
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
7
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M., Ricci J.E., Edris W.A., Sutherlin D.P., Green D.R., and Salvesen G.S. A unified model for apical caspase activation. Mol. Cell 11 (2003) 529-541
-
(2003)
Mol. Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
Ricci, J.E.7
Edris, W.A.8
Sutherlin, D.P.9
Green, D.R.10
Salvesen, G.S.11
-
8
-
-
4544288868
-
Activation of caspases-8 and -10 by FLIP(L)
-
Boatright K.M., Deis C., Denault J.B., Sutherlin D.P., and Salvesen G.S. Activation of caspases-8 and -10 by FLIP(L). Biochem. J. 382 (2004) 651-657
-
(2004)
Biochem. J.
, vol.382
, pp. 651-657
-
-
Boatright, K.M.1
Deis, C.2
Denault, J.B.3
Sutherlin, D.P.4
Salvesen, G.S.5
-
9
-
-
40749153516
-
Cullin-RING ubiquitin ligases: global regulation and activation cycles
-
Bosu D.R., and Kipreos E.T. Cullin-RING ubiquitin ligases: global regulation and activation cycles. Cell Div. 3 (2008) 7
-
(2008)
Cell Div.
, vol.3
, pp. 7
-
-
Bosu, D.R.1
Kipreos, E.T.2
-
10
-
-
34247221276
-
Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6
-
Camus S., Menendez S., Cheok C.F., Stevenson L.F., Lain S., and Lane D.P. Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6. Oncogene 26 (2007) 4059-4070
-
(2007)
Oncogene
, vol.26
, pp. 4059-4070
-
-
Camus, S.1
Menendez, S.2
Cheok, C.F.3
Stevenson, L.F.4
Lain, S.5
Lane, D.P.6
-
11
-
-
32044447161
-
The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover
-
Chang L., Kamata H., Solinas G., Luo J.L., Maeda S., Venuprasad K., Liu Y.C., and Karin M. The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover. Cell 124 (2006) 601-613
-
(2006)
Cell
, vol.124
, pp. 601-613
-
-
Chang, L.1
Kamata, H.2
Solinas, G.3
Luo, J.L.4
Maeda, S.5
Venuprasad, K.6
Liu, Y.C.7
Karin, M.8
-
12
-
-
23144449789
-
Ubiquitin signalling in the NF-kB pathway
-
Chen Z.J. Ubiquitin signalling in the NF-kB pathway. Nat. Cell Biol. 7 (2005) 758-765
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
13
-
-
0033082995
-
IAP family proteins - suppressors of apoptosis
-
Deveraux Q.L., and Reed J.C. IAP family proteins - suppressors of apoptosis. Genes Dev. 13 (1999) 239-252
-
(1999)
Genes Dev.
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
14
-
-
34250308322
-
Apoptosis: a review of programmed cell death
-
Elmore S. Apoptosis: a review of programmed cell death. Toxicol. Pathol. 35 (2007) 495-516
-
(2007)
Toxicol. Pathol.
, vol.35
, pp. 495-516
-
-
Elmore, S.1
-
15
-
-
33846247103
-
Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling
-
Feig C., Tchikov V., Schutze S., and Peter M.E. Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling. EMBO J. 26 (2007) 221-231
-
(2007)
EMBO J.
, vol.26
, pp. 221-231
-
-
Feig, C.1
Tchikov, V.2
Schutze, S.3
Peter, M.E.4
-
16
-
-
0242575197
-
Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases
-
Furukawa M., He Y.J., Borchers C., and Xiong Y. Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases. Nat. Cell Biol. 5 (2003) 1001-1007
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 1001-1007
-
-
Furukawa, M.1
He, Y.J.2
Borchers, C.3
Xiong, Y.4
-
17
-
-
20444430478
-
Apoptotic pathways: ten minutes to dead
-
Green D.R. Apoptotic pathways: ten minutes to dead. Cell 121 (2005) 671-674
-
(2005)
Cell
, vol.121
, pp. 671-674
-
-
Green, D.R.1
-
18
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 (2000) 57-70
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
19
-
-
33747065618
-
NF-kB activation: nondegradative ubiquitination implicates NEMO
-
Israel A. NF-kB activation: nondegradative ubiquitination implicates NEMO. Trends Immunol. 27 (2006) 395-397
-
(2006)
Trends Immunol.
, vol.27
, pp. 395-397
-
-
Israel, A.1
-
20
-
-
3943071150
-
Cytochrome C-mediated apoptosis
-
Jiang X., and Wang X. Cytochrome C-mediated apoptosis. Annu. Rev. Biochem. 73 (2004) 87-106
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 87-106
-
-
Jiang, X.1
Wang, X.2
-
21
-
-
33750370438
-
Distinct signaling pathways in TRAIL- versus tumor necrosis factor-induced apoptosis
-
Jin Z., and El-Deiry W.S. Distinct signaling pathways in TRAIL- versus tumor necrosis factor-induced apoptosis. Mol. Cell. Biol. 26 (2006) 8136-8148
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 8136-8148
-
-
Jin, Z.1
El-Deiry, W.S.2
-
22
-
-
0036009115
-
NF-kB at the crossroads of life and death
-
Karin M., and Lin A. NF-kB at the crossroads of life and death. Nat. Immunol. 3 (2002) 221-227
-
(2002)
Nat. Immunol.
, vol.3
, pp. 221-227
-
-
Karin, M.1
Lin, A.2
-
23
-
-
0033662433
-
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
-
Kischkel F.C., Lawrence D.A., Chuntharapai A., Schow P., Kim K.J., and Ashkenazi A. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5. Immunity 12 (2000) 611-620
-
(2000)
Immunity
, vol.12
, pp. 611-620
-
-
Kischkel, F.C.1
Lawrence, D.A.2
Chuntharapai, A.3
Schow, P.4
Kim, K.J.5
Ashkenazi, A.6
-
24
-
-
33745504241
-
What's Ub chain linkage got to do with it?
-
Kim I., and Rao H. What's Ub chain linkage got to do with it?. Sci. STKE 330 (2006) pe18
-
(2006)
Sci. STKE
, vol.330
-
-
Kim, I.1
Rao, H.2
-
25
-
-
34250331231
-
Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis
-
Kohlhaas S.L., Craxton A., Sun X.M., Pinkoski M.J., and Cohen G.M. Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. J. Biol. Chem. 282 (2007) 12831-12841
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 12831-12841
-
-
Kohlhaas, S.L.1
Craxton, A.2
Sun, X.M.3
Pinkoski, M.J.4
Cohen, G.M.5
-
26
-
-
36849089101
-
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
-
Komatsu M., Waguri S., Koike M., Sou Y.S., Ueno T., Hara T., Mizushima N., Iwata J., Ezaki J., Murata S., et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 131 (2007) 1149-1163
-
(2007)
Cell
, vol.131
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.S.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.8
Ezaki, J.9
Murata, S.10
-
27
-
-
1942533472
-
Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth
-
McDonald III E.R., and El-Deiry W.S. Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth. Proc. Natl. Acad. Sci. USA 101 (2004) 6170-6175
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 6170-6175
-
-
McDonald III, E.R.1
El-Deiry, W.S.2
-
28
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., and Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114 (2003) 181-190
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
29
-
-
33846692198
-
Signal integration and diversification through the p62 scaffold protein
-
Moscat J., Diaz-Meco M.T., and Wooten M.W. Signal integration and diversification through the p62 scaffold protein. Trends Biochem. Sci. 32 (2007) 95-100
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 95-100
-
-
Moscat, J.1
Diaz-Meco, M.T.2
Wooten, M.W.3
-
30
-
-
0030892234
-
Apoptosis by death factor
-
Nagata S. Apoptosis by death factor. Cell 88 (1997) 355-365
-
(1997)
Cell
, vol.88
, pp. 355-365
-
-
Nagata, S.1
-
31
-
-
49549117842
-
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies
-
Newton K., Matsumoto M.L., Wertz I.E., Kirkpatrick D.S., Lill J.R., Tan J., Dugger D., Gordon N., Sidhu S.S., Fellouse F.A., et al. Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies. Cell 134 (2008) 668-678
-
(2008)
Cell
, vol.134
, pp. 668-678
-
-
Newton, K.1
Matsumoto, M.L.2
Wertz, I.E.3
Kirkpatrick, D.S.4
Lill, J.R.5
Tan, J.6
Dugger, D.7
Gordon, N.8
Sidhu, S.S.9
Fellouse, F.A.10
-
32
-
-
34548259958
-
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
-
Pankiv S., Clausen T.H., Lamark T., Brech A., Bruun J.A., Outzen H., Overvatn A., Bjorkoy G., and Johansen T. p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J. Biol. Chem. 282 (2007) 24131-24145
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
33
-
-
0037276437
-
The CD95(APO-1/Fas) DISC and beyond
-
Peter M.E., and Krammer P.H. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ. 10 (2003) 26-35
-
(2003)
Cell Death Differ.
, vol.10
, pp. 26-35
-
-
Peter, M.E.1
Krammer, P.H.2
-
34
-
-
0037756792
-
Context of multiubiquitin chain attachment influences the rate of Sic1 degradation
-
Petroski M.D., and Deshaies R.J. Context of multiubiquitin chain attachment influences the rate of Sic1 degradation. Mol. Cell 11 (2003) 1435-1444
-
(2003)
Mol. Cell
, vol.11
, pp. 1435-1444
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
35
-
-
11244351579
-
Function and regulation of cullin-RING ubiquitin ligases
-
Petroski M.D., and Deshaies R.J. Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 6 (2005) 9-20
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 9-20
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
36
-
-
0842303313
-
Back to the future with ubiquitin
-
Pickart C.M. Back to the future with ubiquitin. Cell 116 (2004) 181-190
-
(2004)
Cell
, vol.116
, pp. 181-190
-
-
Pickart, C.M.1
-
37
-
-
34247345833
-
The apoptosome: signalling platform of cell death
-
Riedl S.J., and Salvesen G.S. The apoptosome: signalling platform of cell death. Nat. Rev. Mol. Cell Biol. 8 (2007) 405-413
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
38
-
-
20244365497
-
p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
-
Sabio G., Arthur J.S., Kuma Y., Peggie M., Carr J., Murray-Tait V., Centeno F., Goedert M., Morrice N.A., and Cuenda A. p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. EMBO J. 24 (2005) 1134-1145
-
(2005)
EMBO J.
, vol.24
, pp. 1134-1145
-
-
Sabio, G.1
Arthur, J.S.2
Kuma, Y.3
Peggie, M.4
Carr, J.5
Murray-Tait, V.6
Centeno, F.7
Goedert, M.8
Morrice, N.A.9
Cuenda, A.10
-
39
-
-
0033667778
-
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
Sprick M.R., Weigand M.A., Rieser E., Rausch C.T., Juo P., Blenis J., Krammer P.H., and Walczak H. FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12 (2000) 599-609
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R.1
Weigand, M.A.2
Rieser, E.3
Rausch, C.T.4
Juo, P.5
Blenis, J.6
Krammer, P.H.7
Walczak, H.8
-
40
-
-
38349114036
-
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases
-
Tan J.M., Wong E.S., Kirkpatrick D.S., Pletnikova O., Ko H.S., Tay S.P., Ho M.W., Troncoso J., Gygi S.P., Lee M.K., et al. Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases. Hum. Mol. Genet. 17 (2008) 431-439
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 431-439
-
-
Tan, J.M.1
Wong, E.S.2
Kirkpatrick, D.S.3
Pletnikova, O.4
Ko, H.S.5
Tay, S.P.6
Ho, M.W.7
Troncoso, J.8
Gygi, S.P.9
Lee, M.K.10
-
41
-
-
1342285692
-
Tumor necrosis factor: an apoptosis JuNKie?
-
Varfolomeev E.E., and Ashkenazi A. Tumor necrosis factor: an apoptosis JuNKie?. Cell 116 (2004) 491-497
-
(2004)
Cell
, vol.116
, pp. 491-497
-
-
Varfolomeev, E.E.1
Ashkenazi, A.2
-
42
-
-
43049152912
-
TNF-α induces two distinct caspase-8 activation pathways
-
Wang L., Du F., and Wang X. TNF-α induces two distinct caspase-8 activation pathways. Cell 133 (2008) 693-703
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
43
-
-
34948894931
-
Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
-
Wagner K.W., Punnoose E.A., Januario T., Lawrence D.A., Pitti R.M., Lancaster K., Lee D., von Goetz M., Yee S.F., Totpal K., et al. Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL. Nat. Med. 13 (2007) 1070-1077
-
(2007)
Nat. Med.
, vol.13
, pp. 1070-1077
-
-
Wagner, K.W.1
Punnoose, E.A.2
Januario, T.3
Lawrence, D.A.4
Pitti, R.M.5
Lancaster, K.6
Lee, D.7
von Goetz, M.8
Yee, S.F.9
Totpal, K.10
-
44
-
-
0032969285
-
Tumor necrosis factor receptor and Fas signaling mechanisms
-
Wallach D., Varfolomeev E.E., Malinin N.L., Goltsev Y.V., Kovalenko A.V., and Boldin M.P. Tumor necrosis factor receptor and Fas signaling mechanisms. Annu. Rev. Immunol. 17 (1999) 331-367
-
(1999)
Annu. Rev. Immunol.
, vol.17
, pp. 331-367
-
-
Wallach, D.1
Varfolomeev, E.E.2
Malinin, N.L.3
Goltsev, Y.V.4
Kovalenko, A.V.5
Boldin, M.P.6
-
45
-
-
3943054838
-
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling
-
Wertz I.E., O'Rourke K.M., Zhou H., Eby M., Aravind L., Seshagiri S., Wu P., Wiesmann C., Baker R., Boone D.L., et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling. Nature 430 (2004) 694-699
-
(2004)
Nature
, vol.430
, pp. 694-699
-
-
Wertz, I.E.1
O'Rourke, K.M.2
Zhou, H.3
Eby, M.4
Aravind, L.5
Seshagiri, S.6
Wu, P.7
Wiesmann, C.8
Baker, R.9
Boone, D.L.10
|