메뉴 건너뛰기




Volumn 105, Issue 45, 2008, Pages 17463-17468

Antigen-mediated T cell expansion regulated by parallel pathways of death

Author keywords

Apoptosis; Autophagy; Necrosis; NF B; Ripk1

Indexed keywords

ANTIGEN; CARRIER PROTEINS AND BINDING PROTEINS; CASPASE 8; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN RIPK1; UNCLASSIFIED DRUG;

EID: 56249132503     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808043105     Document Type: Article
Times cited : (124)

References (61)
  • 1
    • 0034130060 scopus 로고    scopus 로고
    • Accessing complexity: The dynamics of virus-specific T cell responses
    • Doherty PC, Christensen JP (2000) Accessing complexity: The dynamics of virus-specific T cell responses. Annu Rev Immunol 18:561-592.
    • (2000) Annu Rev Immunol , vol.18 , pp. 561-592
    • Doherty, P.C.1    Christensen, J.P.2
  • 2
    • 0037018098 scopus 로고    scopus 로고
    • Estimating the precursor frequency of naive antigen-specific CD8 T cells
    • Blattman JN, et al. (2002) Estimating the precursor frequency of naive antigen-specific CD8 T cells. J Exp Med 195:657-664.
    • (2002) J Exp Med , vol.195 , pp. 657-664
    • Blattman, J.N.1
  • 3
    • 0141958258 scopus 로고    scopus 로고
    • Different dynamics of CD4+ and CD8+ T cell responses during and after acute lymphocytic choriomeningitis virus infection
    • De Boer RJ, Homann D, Perelson AS (2003) Different dynamics of CD4+ and CD8+ T cell responses during and after acute lymphocytic choriomeningitis virus infection. J Immunol 171:3928-3935.
    • (2003) J Immunol , vol.171 , pp. 3928-3935
    • De Boer, R.J.1    Homann, D.2    Perelson, A.S.3
  • 4
    • 0036311492 scopus 로고    scopus 로고
    • On the origin, evolution, and nature of programmed cell death: A timeline of four billion years
    • Ameisen JC (2002) On the origin, evolution, and nature of programmed cell death: A timeline of four billion years. Cell Death Differ 9:367-393.
    • (2002) Cell Death Differ , vol.9 , pp. 367-393
    • Ameisen, J.C.1
  • 5
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • Green DR, Droin N, Pinkoski M (2003) Activation-induced cell death in T cells. Immunol Rev 193:70-81.
    • (2003) Immunol Rev , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 6
    • 0030873556 scopus 로고    scopus 로고
    • Differential requirements for survival and proliferation of CD8 naive or memory T cells
    • Tanchot C, Lemonnier FA, Perarnau B, Freitas AA, Rocha B (1997) Differential requirements for survival and proliferation of CD8 naive or memory T cells. Science 276:2057-2062.
    • (1997) Science , vol.276 , pp. 2057-2062
    • Tanchot, C.1    Lemonnier, F.A.2    Perarnau, B.3    Freitas, A.A.4    Rocha, B.5
  • 8
    • 0029163387 scopus 로고
    • CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
    • Boise LH, et al. (1995) CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 3:87-98.
    • (1995) Immunity , vol.3 , pp. 87-98
    • Boise, L.H.1
  • 9
    • 0029076413 scopus 로고
    • Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice
    • Razvi ES, Jiang Z, Woda BA, Welsh RM (1995) Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice. Am J Pathol 147:79-91.
    • (1995) Am J Pathol , vol.147 , pp. 79-91
    • Razvi, E.S.1    Jiang, Z.2    Woda, B.A.3    Welsh, R.M.4
  • 10
    • 0032005477 scopus 로고    scopus 로고
    • Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
    • Murali-Krishna K, et al. (1998) Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection. Immunity 8:177-187.
    • (1998) Immunity , vol.8 , pp. 177-187
    • Murali-Krishna, K.1
  • 11
    • 2542482697 scopus 로고    scopus 로고
    • Control of T cell viability
    • Marrack P, Kappler J (2004) Control of T cell viability. Annu Rev Immunol 22:765-787.
    • (2004) Annu Rev Immunol , vol.22 , pp. 765-787
    • Marrack, P.1    Kappler, J.2
  • 12
    • 0032546387 scopus 로고    scopus 로고
    • Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1
    • Zhang J, Cado D, Chen A, Kabra NH, Winoto A (1998) Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1. Nature 392:296-300.
    • (1998) Nature , vol.392 , pp. 296-300
    • Zhang, J.1    Cado, D.2    Chen, A.3    Kabra, N.H.4    Winoto, A.5
  • 13
    • 0032472916 scopus 로고    scopus 로고
    • A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
    • Newton K, Harris AW, Bath ML, Smith KGC, Strasser A (1998) A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J 17:706-718.
    • (1998) EMBO J , vol.17 , pp. 706-718
    • Newton, K.1    Harris, A.W.2    Bath, M.L.3    Smith, K.G.C.4    Strasser, A.5
  • 14
    • 0032055344 scopus 로고    scopus 로고
    • A role for FADD in T cell activation and development
    • Walsh CM, et al. (1998) A role for FADD in T cell activation and development. Immunity 8:439-449.
    • (1998) Immunity , vol.8 , pp. 439-449
    • Walsh, C.M.1
  • 15
    • 0040189996 scopus 로고    scopus 로고
    • A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts
    • Hueber AO, Zornig M, Bernard AM, Chautan M, Evan G (2000) A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts. J Biol Chem 275:10453-10462.
    • (2000) J Biol Chem , vol.275 , pp. 10453-10462
    • Hueber, A.O.1    Zornig, M.2    Bernard, A.M.3    Chautan, M.4    Evan, G.5
  • 16
    • 18544383460 scopus 로고    scopus 로고
    • Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
    • Chun HJ, et al. (2002) Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature 419:395-399.
    • (2002) Nature , vol.419 , pp. 395-399
    • Chun, H.J.1
  • 17
    • 0038205938 scopus 로고    scopus 로고
    • The requirements for Fas-associated death domain signaling in mature T cell activation and survival
    • Beisner DR, ChuIH, Arechiga AF, Hedrick SM, Walsh CM (2003) The requirements for Fas-associated death domain signaling in mature T cell activation and survival. J Immunol 171:247-256.
    • (2003) J Immunol , vol.171 , pp. 247-256
    • Beisner, D.R.1    Chu, I.H.2    Arechiga, A.F.3    Hedrick, S.M.4    Walsh, C.M.5
  • 18
    • 0037380628 scopus 로고    scopus 로고
    • Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
    • Salmena L, et al. (2003) Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Genes Dev 17:883-895.
    • (2003) Genes Dev , vol.17 , pp. 883-895
    • Salmena, L.1
  • 19
    • 24744459035 scopus 로고    scopus 로고
    • Cutting edge: Innate immunity conferred by B cells is regulated by caspase-8
    • Beisner DR, Ch'en IL, Kolla RV, Hoffmann A, Hedrick SM (2005) Cutting edge: Innate immunity conferred by B cells is regulated by caspase-8. J Immunol 175:3469-3473.
    • (2005) J Immunol , vol.175 , pp. 3469-3473
    • Beisner, D.R.1    Ch'en, I.L.2    Kolla, R.V.3    Hoffmann, A.4    Hedrick, S.M.5
  • 20
    • 34147165459 scopus 로고    scopus 로고
    • Essential role for caspase-8 in Toll-like receptors and NFκB signaling
    • Lemmers B, et al. (2007) Essential role for caspase-8 in Toll-like receptors and NFκB signaling. J Biol Chem 282:7416-7423.
    • (2007) J Biol Chem , vol.282 , pp. 7416-7423
    • Lemmers, B.1
  • 21
    • 33646879040 scopus 로고    scopus 로고
    • The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells
    • Imtiyaz HZ, et al. (2006) The Fas-associated death domain protein is required in apoptosis and TLR-induced proliferative responses in B cells. J Immunol 176:6852-6861.
    • (2006) J Immunol , vol.176 , pp. 6852-6861
    • Imtiyaz, H.Z.1
  • 22
    • 20044368626 scopus 로고    scopus 로고
    • Requirement for caspase-8 in NF-κB activation by antigen receptor
    • Su H, et al. (2005) Requirement for caspase-8 in NF-κB activation by antigen receptor. Science 307:1465-1468.
    • (2005) Science , vol.307 , pp. 1465-1468
    • Su, H.1
  • 23
    • 17844361968 scopus 로고    scopus 로고
    • Cellular FLIP (Long Form) Regulates CD8+ T Cell Activation through Caspase-8-Dependent NF-κB Activation
    • Dohrman A, et al. (2005) Cellular FLIP (Long Form) Regulates CD8+ T Cell Activation through Caspase-8-Dependent NF-κB Activation. J Immunol 174:5270-5278.
    • (2005) J Immunol , vol.174 , pp. 5270-5278
    • Dohrman, A.1
  • 24
    • 34547111577 scopus 로고    scopus 로고
    • Caspase-8 and c-FLIPL associate in lipid rafts with NF-κB adaptors during T cell activation
    • Misra RS, et al. (2007) Caspase-8 and c-FLIPL associate in lipid rafts with NF-κB adaptors during T cell activation. J Biol Chem 282:19365-19374.
    • (2007) J Biol Chem , vol.282 , pp. 19365-19374
    • Misra, R.S.1
  • 25
    • 29144492116 scopus 로고    scopus 로고
    • Cutting edge: FADD is not required for antigen receptor-mediated NF-κB activation
    • Arechiga AF, et al. (2005) Cutting edge: FADD is not required for antigen receptor-mediated NF-κB activation. J Immunol 175:7800-7804.
    • (2005) J Immunol , vol.175 , pp. 7800-7804
    • Arechiga, A.F.1
  • 26
    • 0028001530 scopus 로고
    • Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death
    • Schulze-Osthoff K, Krammer PH, Droge W (1994) Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death. EMBO J 13:4587-4596.
    • (1994) EMBO J , vol.13 , pp. 4587-4596
    • Schulze-Osthoff, K.1    Krammer, P.H.2    Droge, W.3
  • 27
    • 0032482169 scopus 로고    scopus 로고
    • Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
    • Vercammen D, et al. (1998) Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 187:1477-1485.
    • (1998) J Exp Med , vol.187 , pp. 1477-1485
    • Vercammen, D.1
  • 28
    • 0034638827 scopus 로고    scopus 로고
    • Necrotic death pathway in Fas receptor signaling
    • Matsumura H, et al. (2000) Necrotic death pathway in Fas receptor signaling. J Cell Biol 151:1247-1256.
    • (2000) J Cell Biol , vol.151 , pp. 1247-1256
    • Matsumura, H.1
  • 29
    • 5944233768 scopus 로고    scopus 로고
    • Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
    • Holler N, et al. (2000) Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1:489-495.
    • (2000) Nat Immunol , vol.1 , pp. 489-495
    • Holler, N.1
  • 30
    • 33644840693 scopus 로고    scopus 로고
    • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
    • Degterev A, et al. (2005) Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1:112-119.
    • (2005) Nat Chem Biol , vol.1 , pp. 112-119
    • Degterev, A.1
  • 31
    • 0029966211 scopus 로고    scopus 로고
    • Regulation of T cell activation by CD28 and CTLA4
    • Noel PJ, Boise LH, Thompson CB (1996) Regulation of T cell activation by CD28 and CTLA4. Adv Exp Med Biol 406:209-217.
    • (1996) Adv Exp Med Biol , vol.406 , pp. 209-217
    • Noel, P.J.1    Boise, L.H.2    Thompson, C.B.3
  • 32
    • 0036200194 scopus 로고    scopus 로고
    • Protein kinase B (Akt) regulation and function in T lymphocytes
    • Cantrell D (2002) Protein kinase B (Akt) regulation and function in T lymphocytes. Semin Immunol 14:19-26.
    • (2002) Semin Immunol , vol.14 , pp. 19-26
    • Cantrell, D.1
  • 33
    • 0036679733 scopus 로고    scopus 로고
    • It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation
    • Kane LP, Lin J, Weiss A (2002) It's all Rel-ative: NF-κB and CD28 costimulation of T-cell activation. Trends Immunol 23:413-420.
    • (2002) Trends Immunol , vol.23 , pp. 413-420
    • Kane, L.P.1    Lin, J.2    Weiss, A.3
  • 34
    • 0035839640 scopus 로고    scopus 로고
    • FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery
    • Zhang J, Kabra NH, Cado D, Kang C, Winoto A (2001) FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery. J Biol Chem 276:29815-29818.
    • (2001) J Biol Chem , vol.276 , pp. 29815-29818
    • Zhang, J.1    Kabra, N.H.2    Cado, D.3    Kang, C.4    Winoto, A.5
  • 35
    • 38449096218 scopus 로고    scopus 로고
    • A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2
    • Arechiga AF, et al. (2007) A Fas-associated death domain protein/caspase-8-signaling axis promotes S-phase entry and maintains S6 kinase activity in T cells responding to IL-2. J Immunol 179:5291-5300.
    • (2007) J Immunol , vol.179 , pp. 5291-5300
    • Arechiga, A.F.1
  • 36
    • 33749178260 scopus 로고    scopus 로고
    • Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response
    • Festjens N, Vanden Berghe T, Vandenabeele P (2006) Necrosis, a well-orchestrated form of cell demise: Signalling cascades, important mediators and concomitant immune response. Biochim Biophys Acta 1757:1371-1387.
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 1371-1387
    • Festjens, N.1    Vanden Berghe, T.2    Vandenabeele, P.3
  • 37
    • 33846018602 scopus 로고    scopus 로고
    • Cell death by necrosis: Towards a molecular definition
    • Golstein P, Kroemer G (2007) Cell death by necrosis: Towards a molecular definition. Trends Biochem Sci 32:37-43.
    • (2007) Trends Biochem Sci , vol.32 , pp. 37-43
    • Golstein, P.1    Kroemer, G.2
  • 38
    • 0025751550 scopus 로고
    • bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ (1991) bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67:879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 39
    • 0025786164 scopus 로고
    • bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship
    • Strasser A, Harris AW, Cory S (1991) bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship. Cell 67:889-899.
    • (1991) Cell , vol.67 , pp. 889-899
    • Strasser, A.1    Harris, A.W.2    Cory, S.3
  • 40
    • 0028984843 scopus 로고
    • Bcl-XL and Bcl-2 repress a common pathway of cell death
    • Chao DT, et al. (1995) Bcl-XL and Bcl-2 repress a common pathway of cell death. J Exp Med 182:821-828.
    • (1995) J Exp Med , vol.182 , pp. 821-828
    • Chao, D.T.1
  • 41
    • 0027618650 scopus 로고
    • Regulation of the NF-κB/rel transcription factor and IκB inhibitor system
    • Liou HC, Baltimore D (1993) Regulation of the NF-κB/rel transcription factor and IκB inhibitor system. Curr Opin Cell Biol 5:477-487.
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 477-487
    • Liou, H.C.1    Baltimore, D.2
  • 42
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Ghosh S (2004) Signaling to NF-κB. Genes Dev 18:2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 43
    • 24944489952 scopus 로고    scopus 로고
    • Stimulus specificity of gene expression programs determined by temporal control of IKK activity
    • Werner SL, Barken D, Hoffmann A (2005) Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309:1857-1861.
    • (2005) Science , vol.309 , pp. 1857-1861
    • Werner, S.L.1    Barken, D.2    Hoffmann, A.3
  • 44
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor κB signaling
    • Hoffmann A, Baltimore D (2006) Circuitry of nuclear factor κB signaling. Immunol Rev 210:171-186.
    • (2006) Immunol Rev , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 45
    • 42249102086 scopus 로고    scopus 로고
    • Identification of RIP1 kinase as a specific cellular target of necrostatins
    • Degterev A, et al. (2008) Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol.
    • (2008) Nat Chem Biol
    • Degterev, A.1
  • 46
    • 0029054725 scopus 로고
    • RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95)
    • yeast and causes cell death
    • Stanger BZ, Leder P, Lee TH, Kim E, Seed B (1995) RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81:513-523.
    • (1995) Cell , vol.81 , pp. 513-523
    • Stanger, B.Z.1    Leder, P.2    Lee, T.H.3    Kim, E.4    Seed, B.5
  • 47
    • 0033214236 scopus 로고    scopus 로고
    • Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
    • Lin Y, Devin A, Rodriguez Y, Liu ZG (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13:2514-2526.
    • (1999) Genes Dev , vol.13 , pp. 2514-2526
    • Lin, Y.1    Devin, A.2    Rodriguez, Y.3    Liu, Z.G.4
  • 48
    • 0033955634 scopus 로고    scopus 로고
    • Activation of a pro-apoptotic amplification loop through inhibition of NF-κB-dependent survival signals by caspase-mediated inactivation of RIP
    • Martinon F, Holler N, Richard C, Tschopp J (2000) Activation of a pro-apoptotic amplification loop through inhibition of NF-κB-dependent survival signals by caspase-mediated inactivation of RIP. FEBS Lett 468:134-136.
    • (2000) FEBS Lett , vol.468 , pp. 134-136
    • Martinon, F.1    Holler, N.2    Richard, C.3    Tschopp, J.4
  • 49
    • 0034648648 scopus 로고    scopus 로고
    • Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP
    • Kim JW, Choi EJ, Joe CO (2000) Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP. Oncogene 19:4491-4499.
    • (2000) Oncogene , vol.19 , pp. 4491-4499
    • Kim, J.W.1    Choi, E.J.2    Joe, C.O.3
  • 51
    • 0141997719 scopus 로고    scopus 로고
    • Apoptosis prevention as a mechanism of immune evasion
    • Aubert M, Jerome KR (2003) Apoptosis prevention as a mechanism of immune evasion. Int Rev Immunol 22:361-371.
    • (2003) Int Rev Immunol , vol.22 , pp. 361-371
    • Aubert, M.1    Jerome, K.R.2
  • 52
    • 0037345810 scopus 로고    scopus 로고
    • The survival of antigen-stimulated T cells requires NFκB-mediated inhibition of p73 expression
    • Wan YY, DeGregori J (2003) The survival of antigen-stimulated T cells requires NFκB-mediated inhibition of p73 expression. Immunity 18:331-342.
    • (2003) Immunity , vol.18 , pp. 331-342
    • Wan, Y.Y.1    DeGregori, J.2
  • 54
    • 0034663779 scopus 로고    scopus 로고
    • The NF-κB cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes
    • Khoshnan A, et al. (2000) The NF-κB cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J Immunol 165:1743-1754.
    • (2000) J Immunol , vol.165 , pp. 1743-1754
    • Khoshnan, A.1
  • 55
    • 6344279932 scopus 로고    scopus 로고
    • Caspase inhibition blocks human T cell proliferation by suppressing appropriate regulation of IL-2, CD25, and cell cycle-associated proteins
    • Falk M, et al. (2004) Caspase inhibition blocks human T cell proliferation by suppressing appropriate regulation of IL-2, CD25, and cell cycle-associated proteins. J Immunol 173:5077-5085.
    • (2004) J Immunol , vol.173 , pp. 5077-5085
    • Falk, M.1
  • 56
    • 23744487497 scopus 로고    scopus 로고
    • Cellular FLICE-inhibitory protein is required for T cell survival and cycling
    • Chau H, et al. (2005) Cellular FLICE-inhibitory protein is required for T cell survival and cycling. J Exp Med 202:405-413.
    • (2005) J Exp Med , vol.202 , pp. 405-413
    • Chau, H.1
  • 57
    • 0033280694 scopus 로고    scopus 로고
    • Lymphocyte survival: The struggle against death
    • Arch RH, Thompson CB (1999) Lymphocyte survival: The struggle against death. Annu Rev Cell Dev Biol 15:113-140.
    • (1999) Annu Rev Cell Dev Biol , vol.15 , pp. 113-140
    • Arch, R.H.1    Thompson, C.B.2
  • 58
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O, Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-190.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 59
    • 20144381544 scopus 로고    scopus 로고
    • Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
    • Pyo JO, et al. (2005) Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 280:20722-20729.
    • (2005) J Biol Chem , vol.280 , pp. 20722-20729
    • Pyo, J.O.1
  • 60
    • 2542527768 scopus 로고    scopus 로고
    • Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-κB activation pathways
    • Zarnegar B, et al. (2004) Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-κB activation pathways. Proc Natl Acad Sci USA 101:8108-8113.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8108-8113
    • Zarnegar, B.1
  • 61
    • 17844407707 scopus 로고    scopus 로고
    • A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase II in T cells: From activation to unresponsiveness
    • Lin MY, Zal T, Ch'en IL, Gascoigne NR, Hedrick SM (2005) A pivotal role for the multifunctional calcium/calmodulin-dependent protein kinase II in T cells: From activation to unresponsiveness. J Immunol 174:5583-5592.
    • (2005) J Immunol , vol.174 , pp. 5583-5592
    • Lin, M.Y.1    Zal, T.2    Ch'en, I.L.3    Gascoigne, N.R.4    Hedrick, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.