Loss of the Tumor Suppressor CYLD Enhances Wnt/β-Catenin Signaling through K63-Linked Ubiquitination of Dvl

Molecular Cell

Volumn 37, Issue 5, 2010, Pages 607-619

  Tauriello, Daniele V F ^a   Haegebarth, Andrea ^b   Kuper, Ineke ^a   Edelmann, Mariola J ^c   Henraat, Marre ^a   Canninga van Dijk, Marijke R ^a   Kessler, Benedikt M ^c   Clevers, Hans ^b   Maurice, Madelon M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b HUBRECHT INSTITUTE   (Netherlands)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

HUMDISEASE; PROTEINS; SIGNALING

Indexed keywords

BETA CATENIN; DISHEVELLED PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; UBIQUITIN K63; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYLD TUMOR SUPPRESSOR GENE; CYLINDROMA; GENE ACTIVATION; GENE LOSS; GENE MUTATION; HUMAN; HUMAN CELL; PROTEIN POLYMERIZATION; TUMOR SUPPRESSOR GENE; UBIQUITINATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BETA CATENIN; CARCINOMA, ADENOID CYSTIC; CARCINOMA, SKIN APPENDAGE; CELL PROLIFERATION; HELA CELLS; HUMANS; LYSINE; MICE; MUTATION; NF-KAPPA B; PHOSPHOPROTEINS; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TIME FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION; WNT PROTEINS;

EID: 77649259009     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.01.035     Document Type: Article

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