-
1
-
-
42049119644
-
Special anniversary review: Twenty-five years of human immunodeficiency virus research: Successes and challenges
-
Weiss RA. Special anniversary review: twenty-five years of human immunodeficiency virus research: successes and challenges. Clin Exp Immunol 2008; 152(2): 201-10.
-
(2008)
Clin Exp Immunol
, vol.152
, Issue.2
, pp. 201-210
-
-
Weiss, R.A.1
-
2
-
-
79958166239
-
Thirty years of HIV and AIDS: Future challenges and opportunities
-
Dieffenbach CW, Fauci, AS. Thirty years of HIV and AIDS: future challenges and opportunities. Ann Intern Med 2011; 154(11): 766-71.
-
(2011)
Ann Intern Med
, vol.154
, Issue.11
, pp. 766-771
-
-
Dieffenbach, C.W.1
Fauci, A.S.2
-
3
-
-
77953841413
-
Microbicides in the Prevention of HIV Infection Current Status and Future Directions
-
Nuttall J. Microbicides in the Prevention of HIV Infection Current Status and Future Directions. Drugs 2010; 70(10): 1231-43.
-
(2010)
Drugs
, vol.70
, Issue.10
, pp. 1231-1243
-
-
Nuttall, J.1
-
4
-
-
73349094086
-
Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
-
Rerks-Ngarm S, Pitisuttithum P, Nitayaphan S, et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N Engl J Med 2009; 361(23): 2209-20.
-
(2009)
N Engl J Med
, vol.361
, Issue.23
, pp. 2209-2220
-
-
Rerks-Ngarm, S.1
Pitisuttithum, P.2
Nitayaphan, S.3
-
5
-
-
84859393693
-
Immune-correlates analysis of an HIV-1 vaccine efficacy trial
-
Haynes BF, Gilbert PB, McElrath MJ, et al. Immune-correlates analysis of an HIV-1 vaccine efficacy trial. N Engl J Med 2012; 366(14): 1275-86.
-
(2012)
N Engl J Med
, vol.366
, Issue.14
, pp. 1275-1286
-
-
Haynes, B.F.1
Gilbert, P.B.2
McElrath, M.J.3
-
6
-
-
84867854910
-
Update on progress in HIV vaccine development
-
Watkins DI, Update on progress in HIV vaccine development. Top Antivir Med 2012; 20(2): 30-1.
-
(2012)
Top Antivir Med
, vol.20
, Issue.2
, pp. 30-31
-
-
Watkins, D.I.1
-
9
-
-
4344673662
-
Mapping the roots of HIV/AIDS complacency: Implications for program and policy development
-
Valdiserri RO. Mapping the roots of HIV/AIDS complacency: Implications for program and policy development. Aids Education and Prevention 2004; 16(5): 426-39.
-
(2004)
Aids Education and Prevention
, vol.16
, Issue.5
, pp. 426-439
-
-
Valdiserri, R.O.1
-
10
-
-
13844321964
-
A future free of HIV: What will it take?
-
Valdiserri RO. A future free of HIV: What will it take? J Publ Health Manag Pract 2005; 11(1): 1-3.
-
(2005)
J Publ Health Manag Pract
, vol.11
, Issue.1
, pp. 1-3
-
-
Valdiserri, R.O.1
-
11
-
-
78650549662
-
Pre-exposure chemoprophylaxis for HIV prevention in men who have sex with men
-
Grant RM, Lama JR, AndersonPL, et al. Pre-exposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363(27): 2587-99.
-
(2010)
N Engl J Med
, vol.363
, Issue.27
, pp. 2587-2599
-
-
Grant, R.M.1
Lama, J.R.2
Anderson, P.L.3
-
12
-
-
58549113211
-
Heterosexual risk of HIV-1 infection per sexual act: Systematic review and meta-analysis of observational studies
-
Boily MC, Baggaley RF, Wang L, et al. Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studies. Lancet Infect Dis 2009; 9(2): 118-29.
-
(2009)
Lancet Infect Dis
, vol.9
, Issue.2
, pp. 118-129
-
-
Boily, M.C.1
Baggaley, R.F.2
Wang, L.3
-
13
-
-
73549099755
-
Development of topical microbicides to prevent the sexual transmission of HIV
-
Buckheit RW Jr, Watson KM, Morrow KM, Ham AS. Development of topical microbicides to prevent the sexual transmission of HIV. Antiviral Res 2010; 85(1): 142-58.
-
(2010)
Antiviral Res
, vol.85
, Issue.1
, pp. 142-158
-
-
Buckheit Jr., R.W.1
Watson, K.M.2
Morrow, K.M.3
Ham, A.S.4
-
14
-
-
33847390394
-
Microbicide drug candidates to prevent HIV infection
-
Balzarini J, van Damme L. Microbicide drug candidates to prevent HIV infection. Lancet 2007; 369(9563): 787-97.
-
(2007)
Lancet
, vol.369
, Issue.9563
, pp. 787-797
-
-
Balzarini, J.1
van Damme, L.2
-
15
-
-
60549100211
-
Topical application of entry inhibitors as virustats to prevent sexual transmission of HIV infection
-
doi: 10.1186/1742-4690-5-116
-
Lederman MM, Jump R, Pilch-Cooper HA, Root M, Sieg SF. Topical application of entry inhibitors as virustats to prevent sexual transmission of HIV infection. Retrovirology 2008; 5, doi: 10.1186/1742-4690-5-116.
-
(2008)
Retrovirology
, pp. 5
-
-
Lederman, M.M.1
Jump, R.2
Pilch-Cooper, H.A.3
Root, M.4
Sieg, S.F.5
-
17
-
-
77955930318
-
Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women
-
Abdool Karim Q, Abdool Karim SS, Frohlich JA, et al. Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women. Science 2010; 329(5996): 1168-74.
-
(2010)
Science
, vol.329
, Issue.5996
, pp. 1168-1174
-
-
Abdool, K.Q.1
Abdool, K.S.S.2
Frohlich, J.A.3
-
18
-
-
84862847012
-
Overview of microbicides for the prevention of human immunodeficiency virus
-
Abdool Karim SS, Baxter C. Overview of microbicides for the prevention of human immunodeficiency virus. Best Pract Res Clin Obstet Gynaecol 2012; 26(4): 427-39.
-
(2012)
Best Pract Res Clin Obstet Gynaecol
, vol.26
, Issue.4
, pp. 427-439
-
-
Abdool, K.S.S.1
Baxter, C.2
-
19
-
-
33748990336
-
Which topical microbicides for blocking HIV-1 transmission will work in the real world?
-
Klasse PJ, Shattock RJ, Moore JP. Which topical microbicides for blocking HIV-1 transmission will work in the real world? PLoS Med 2006; 3(9): 1501-7.
-
(2006)
PLoS Med
, vol.3
, Issue.9
, pp. 1501-1507
-
-
Klasse, P.J.1
Shattock, R.J.2
Moore, J.P.3
-
20
-
-
18144365830
-
In vitro and in vivo - the story of nonoxynol 9
-
Hillier SL Moench T, Shattock R, Black R, Reichelderfer P, Veronese F. In vitro and in vivo - the story of nonoxynol 9. J AIDS 2005; 39(1): 1-8.
-
(2005)
J AIDS
, vol.39
, Issue.1
, pp. 1-8
-
-
Hillier, S.L.1
Moench, T.2
Shattock, R.3
Black, R.4
Reichelderfer, P.5
Veronese, F.6
-
21
-
-
51449112802
-
A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections
-
Ndesendo VMK, Pillay V, Choonara YE, Buchmann E, Bayever DN, Meyer LC. A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infections. Aaps Pharmsc 2008; 9(2): 505-20.
-
(2008)
Aaps Pharmsc
, vol.9
, Issue.2
, pp. 505-520
-
-
Ndesendo, V.M.K.1
Pillay, V.2
Choonara, Y.E.3
Buchmann, E.4
Bayever, D.N.5
Meyer, L.C.6
-
23
-
-
0037625131
-
Transmission, acute hiv-1 infection and the quest for strategies to prevent infection
-
Pope M, Haase AT. Transmission, acute hiv-1 infection and the quest for strategies to prevent infection. Nat Med 2003; 9(7): 847-52.
-
(2003)
Nat Med
, vol.9
, Issue.7
, pp. 847-852
-
-
Pope, M.1
Haase, A.T.2
-
24
-
-
34147186281
-
Current concepts of HIV transmission
-
Morrow G, Vachot L, Vagenas P, Robbiani M. Current concepts of HIV transmission. Curr HIV/AIDS Res 2007; 4(1): 29-35.
-
(2007)
Curr HIV/AIDS Res
, vol.4
, Issue.1
, pp. 29-35
-
-
Morrow, G.1
Vachot, L.2
Vagenas, P.3
Robbiani, M.4
-
25
-
-
61449159825
-
HIV infection of the genital mucosa in women
-
Hladik F, Hope TJ. HIV infection of the genital mucosa in women. Curr HIV/AIDS Rep 2009; 6(1): 20-8.
-
(2009)
Curr HIV/AIDS Rep
, vol.6
, Issue.1
, pp. 20-28
-
-
Hladik, F.1
Hope, T.J.2
-
26
-
-
77949409948
-
Targeting early infection to prevent HIV-1 mucosal transmission
-
Haase AT. Targeting early infection to prevent HIV-1 mucosal transmission. Nature 2010; 464(7286): 217-23.
-
(2010)
Nature
, vol.464
, Issue.7286
, pp. 217-223
-
-
Haase, A.T.1
-
27
-
-
0031958939
-
Vaginal transmission of SIV: Assessing infectivity and hormonal influences in macaques inoculated with cell-free and cell-associated viral stocks
-
Sodora DL, Gettie A, Miller CJ, Marx PA. Vaginal transmission of SIV: assessing infectivity and hormonal influences in macaques inoculated with cell-free and cell-associated viral stocks. AIDS Res Hum Retroviruses 1998; 14: S119-23.
-
(1998)
AIDS Res Hum Retroviruses
, vol.14
-
-
Sodora, D.L.1
Gettie, A.2
Miller, C.J.3
Marx, P.A.4
-
28
-
-
0036150902
-
Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent
-
Khanna KV, Whaley KJ, Zeitlin L, et al. Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent. J Clin Invest 2002; 109(6): 205-11.
-
(2002)
J Clin Invest
, vol.109
, Issue.6
, pp. 205-211
-
-
Khanna, K.V.1
Whaley, K.J.2
Zeitlin, L.3
-
29
-
-
0041815188
-
Immunodeficiency virus exploitation of dendritic cells in the early steps of infection
-
Teleshova NI, Frank MP. Immunodeficiency virus exploitation of dendritic cells in the early steps of infection. J Leukoc Biol 2003; 74(5): 683-90.
-
(2003)
J Leukoc Biol
, vol.74
, Issue.5
, pp. 683-690
-
-
Teleshova, N.I.1
Frank, M.P.2
-
30
-
-
0038407687
-
DC-SIGN: A novel HIV receptor on DCs that mediates HIV-1 transmission
-
Geijtenbeek, TBH, van Kooyk Y. DC-SIGN: A novel HIV receptor on DCs that mediates HIV-1 transmission. Curr Top Microbiol Immunol 2003: 109(2); 31-54.
-
(2003)
Curr Top Microbiol Immunol
, vol.109
, Issue.2
, pp. 31-54
-
-
Geijtenbeek, T.B.H.1
van Kooyk, Y.2
-
31
-
-
20544475417
-
Viral and host factors in the pathogenesis of HIV infection
-
Derdeyn CA, Silvestri G. Viral and host factors in the pathogenesis of HIV infection. Curr Op Immunol 2005; 17(4): 366-73.
-
(2005)
Curr Op Immunol
, vol.17
, Issue.4
, pp. 366-373
-
-
Derdeyn, C.A.1
Silvestri, G.2
-
32
-
-
0033952103
-
Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
-
Baba TW, Liska V, Hofmann-Lehmann R, et al. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med 2000; 6(2): 200-6.
-
(2000)
Nat Med
, vol.6
, Issue.2
, pp. 200-206
-
-
Baba, T.W.1
Liska, V.2
Hofmann-Lehmann, R.3
-
33
-
-
66049139947
-
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
-
Salazar-Gonzalez JF, Salazar MG, Keele BF, et al. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med 2009; 206(6): 1273-89.
-
(2009)
J Exp Med
, vol.206
, Issue.6
, pp. 1273-1289
-
-
Salazar-Gonzalez, J.F.1
Salazar, M.G.2
Keele, B.F.3
-
34
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol 1999; 17: 657-700.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
35
-
-
0344352497
-
Mucosal transmission of pathogenic CXCR4-utilizing SHIVSF33A variants in rhesus macaques
-
Harouse JM, Tan RC, Gettie A, et al. Mucosal transmission of pathogenic CXCR4-utilizing SHIVSF33A variants in rhesus macaques. Virology 1998; 248(1): 95-107.
-
(1998)
Virology
, vol.248
, Issue.1
, pp. 95-107
-
-
Harouse, J.M.1
Tan, R.C.2
Gettie, A.3
-
36
-
-
12144289425
-
Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission
-
Derdeyn CA, Decker JM, Bibollet-Ruche F, et al. Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science 2004; 303(5666): 2019-22.
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2019-2022
-
-
Derdeyn, C.A.1
Decker, J.M.2
Bibollet-Ruche, F.3
-
37
-
-
33646751914
-
Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1
-
Li B, Decker JM, Johnson RW, et al. Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1. J Virol 2006; 80(11): 5211-8.
-
(2006)
J Virol
, vol.80
, Issue.11
, pp. 5211-5218
-
-
Li, B.1
Decker, J.M.2
Johnson, R.W.3
-
38
-
-
70349695689
-
Escape from Autologous Neutralizing Antibodies in Acute/Early Subtype C HIV-1 Infection Requires Multiple Pathways
-
Rong R, Li B, Lynch RM, et al. Escape from Autologous Neutralizing Antibodies in Acute/Early Subtype C HIV-1 Infection Requires Multiple Pathways. PLoS Pathog 2009; 5(9): e1000594.
-
(2009)
PLoS Pathog
, vol.5
, Issue.9
-
-
Rong, R.1
Li, B.2
Lynch, R.M.3
-
39
-
-
0345569681
-
Inhibiting sexual transmission of HIV-1 infection
-
Shattock RJ, Moore JP. Inhibiting sexual transmission of HIV-1 infection. Nat Rev Microbiol 2003; 1(8): 25-34.
-
(2003)
Nat Rev Microbiol
, vol.1
, Issue.8
, pp. 25-34
-
-
Shattock, R.J.1
Moore, J.P.2
-
40
-
-
0042368611
-
Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89. 6P in macaques
-
Tsai CC, Emau P, Jiang Y, et al. Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89. 6P in macaques. AIDS Res Hum Retroviruses 2003; 19(7): 535-41.
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, Issue.7
, pp. 535-541
-
-
Tsai, C.C.1
Emau, P.2
Jiang, Y.3
-
41
-
-
0742272702
-
Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models
-
Tsai CC, Emau P, Jiang Y, et al. Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models. AIDS Res Hum Retroviruses 2004; 20(1): 11-8.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.1
, pp. 11-18
-
-
Tsai, C.C.1
Emau, P.2
Jiang, Y.3
-
42
-
-
5644247983
-
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
-
Lederman MM, Veazey RS, Offord R, et al. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 2004; 306(5695): 485-7.
-
(2004)
Science
, vol.306
, Issue.5695
, pp. 485-487
-
-
Lederman, M.M.1
Veazey, R.S.2
Offord, R.3
-
43
-
-
27744571425
-
Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion
-
Veazey RS, Klasse PJ, Schader SM, et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion. Nature 2005; 438(7064): 99-102.
-
(2005)
Nature
, vol.438
, Issue.7064
, pp. 99-102
-
-
Veazey, R.S.1
Klasse, P.J.2
Schader, S.M.3
-
44
-
-
66049157864
-
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1
-
Keele BF, Klasse PJ, Schader SM, et al. Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. J Exp Med 2009; 206(5): 1117-34.
-
(2009)
J Exp Med
, vol.206
, Issue.5
, pp. 1117-1134
-
-
Keele, B.F.1
Klasse, P.J.2
Schader, S.M.3
-
45
-
-
77953784170
-
A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251
-
Stone M, Keele BF, Ma ZM, et al. A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251. J Virol 2010; 84(14): 7083-95.
-
(2010)
J Virol
, vol.84
, Issue.14
, pp. 7083-7095
-
-
Stone, M.1
Keele, B.F.2
Ma, Z.M.3
-
46
-
-
0034034688
-
Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides
-
Greenhead P Hayes P, Watts PS, Laing KG, Griffin GE, Shattock RJ. Parameters of human immunodeficiency virus infection of human cervical tissue and inhibition by vaginal virucides. J Virol 2000; 74(12): 5577-86.
-
(2000)
J Virol
, vol.74
, Issue.12
, pp. 5577-5586
-
-
Greenhead, P.1
Hayes, P.2
Watts, P.S.3
Laing, K.G.4
Griffin, G.E.5
Shattock, R.J.6
-
47
-
-
0034053686
-
In vitro models of mucosal HIV transmission
-
Shattock RJ, Griffin GE, Gorodeski GI, et al. In vitro models of mucosal HIV transmission. Nat Med 2000; 6(6): 607-8.
-
(2000)
Nat Med
, vol.6
, Issue.6
, pp. 607-608
-
-
Shattock, R.J.1
Griffin, G.E.2
Gorodeski, G.I.3
-
48
-
-
2442428094
-
Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue
-
Hu Q, Frank I, Williams V, et al. Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue. J Exp Med 2004; 199(8): 1065-75.
-
(2004)
J Exp Med
, vol.199
, Issue.8
, pp. 1065-1075
-
-
Hu, Q.1
Frank, I.2
Williams, V.3
-
49
-
-
84860194483
-
Preclinical evaluation of the HIV-1 fusion inhibitor L'644 as a potential candidate microbicide
-
Harman S, Herrera C, Armanasco N, Nuttall J, Shattock RJ. Preclinical evaluation of the HIV-1 fusion inhibitor L'644 as a potential candidate microbicide. Antimicrob Agents Chemother 2012; 56(5): 2347-56.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.5
, pp. 2347-2356
-
-
Harman, S.1
Herrera, C.2
Armanasco, N.3
Nuttall, J.4
Shattock, R.J.5
-
50
-
-
59849088564
-
Cyanovirin-N potently inhibits human immunodeficiency virus type 1 infection in cellular and cervical explant models
-
Buffa V, Stieh D, Mamhood N, Hu Q, Fletcher P, Shattock RJ. Cyanovirin-N potently inhibits human immunodeficiency virus type 1 infection in cellular and cervical explant models. J Gen Virol 2009; 90(Pt 1): 234-43.
-
(2009)
J Gen Virol
, vol.90
, Issue.PART 1
, pp. 234-243
-
-
Buffa, V.1
Stieh, D.2
Mamhood, N.3
Hu, Q.4
Fletcher, P.5
Shattock, R.J.6
-
51
-
-
65549099593
-
Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component
-
O'Keefe BR, Vojdani F, Buffa V, et al. Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component. Proc Natl Acad Sci USA 2009; 106(15): 6099-104.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.15
, pp. 6099-6104
-
-
O'Keefe, B.R.1
Vojdani, F.2
Buffa, V.3
-
52
-
-
84872028026
-
MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques
-
Dereuddre-Bosquet N, Morellato-Castillo L, Brouwers J, et al. MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques. PLoS Pathog 2012; 8(12): e1003071.
-
(2012)
PLoS Pathog
, vol.8
, Issue.12
-
-
Dereuddre-Bosquet, N.1
Morellato-Castillo, L.2
Brouwers, J.3
-
53
-
-
20244368227
-
Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda
-
Wawer MJ, Gray RH, Sewankambo NK, et al. Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis 2005; 191(9): 1403-9.
-
(2005)
J Infect Dis
, vol.191
, Issue.9
, pp. 1403-1409
-
-
Wawer, M.J.1
Gray, R.H.2
Sewankambo, N.K.3
-
54
-
-
77954051000
-
High multiplicity infection by HIV-1 in men who have sex with men
-
Li H, Bar KJ, Wang S, et al. High multiplicity infection by HIV-1 in men who have sex with men. PLoS Pathog 2010; 6(5): e1000890.
-
(2010)
PLoS Pathog
, vol.6
, Issue.5
-
-
Li, H.1
Bar, K.J.2
Wang, S.3
-
55
-
-
0242535591
-
Measuring the infectiousness of persons with HIV-1: Opportunities for preventing sexual HIV-1 transmission
-
Baeten JM, Overbaugh J. Measuring the infectiousness of persons with HIV-1: opportunities for preventing sexual HIV-1 transmission. Curr HIV Res 2003; 1(1): 69-86.
-
(2003)
Curr HIV Res
, vol.1
, Issue.1
, pp. 69-86
-
-
Baeten, J.M.1
Overbaugh, J.2
-
56
-
-
0037508515
-
Topical microbicides for disease prevention: Status and challenges
-
Harrison PF, Rosenberg Z, Bowcut J. Topical microbicides for disease prevention: status and challenges. Clin Infect Dis 2003; 36(10): 1290-4.
-
(2003)
Clin Infect Dis
, vol.36
, Issue.10
, pp. 1290-1294
-
-
Harrison, P.F.1
Rosenberg, Z.2
Bowcut, J.3
-
57
-
-
0346025452
-
Clinical development of microbicides for the prevention of hiv infection
-
D'Cruz OJ, Uckun FM. Clinical development of microbicides for the prevention of hiv infection. Curr Pharml Des 2004; 10(8): 315-36.
-
(2004)
Curr Pharml Des
, vol.10
, Issue.8
, pp. 315-336
-
-
D'Cruz, O.J.1
Uckun, F.M.2
-
58
-
-
39649091895
-
Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission
-
Masse PJ, Shattock R, Moore JP. Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission. Annu Rev Med 2008; 59: 455-71.
-
(2008)
Annu Rev Med
, vol.59
, pp. 455-471
-
-
Masse, P.J.1
Shattock, R.2
Moore, J.P.3
-
59
-
-
57349176596
-
Cellulose Sulfate for Prevention of HIV Infection Reply
-
van Damme L, Taylor D. Cellulose Sulfate for Prevention of HIV Infection Reply. N Engl J Med 2008; 359(19): 2067-8.
-
(2008)
N Engl J Med
, vol.359
, Issue.19
, pp. 2067-2068
-
-
van Damme, L.1
Taylor, D.2
-
60
-
-
80054955393
-
Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus
-
Lagenaur LA, Sanders-Beer BE, Brichacek B, et al. Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus. Mucosal Immunol 2011; 4(6): 648-57.
-
(2011)
Mucosal Immunol
, vol.4
, Issue.6
, pp. 648-657
-
-
Lagenaur, L.A.1
Sanders-Beer, B.E.2
Brichacek, B.3
-
61
-
-
3042726798
-
Treatment for adult HIV Infection - 2004 recommendations of the International AIDS societyUSA panel
-
Hammer SM, Saag MS, Schechter M, et al. Treatment for adult HIV Infection - 2004 recommendations of the International AIDS societyUSA panel. JAMA 2004; 292(3): 251-65.
-
(2004)
JAMA
, vol.292
, Issue.3
, pp. 251-265
-
-
Hammer, S.M.1
Saag, M.S.2
Schechter, M.3
-
62
-
-
0141816744
-
Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4
-
Chang TL, Chang CH, Simpson DA, et al. Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4. Proc Natl Acad Sci USA 2003; 100(20): 11672-7.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.20
, pp. 11672-11677
-
-
Chang, T.L.1
Chang, C.H.2
Simpson, D.A.3
-
63
-
-
27944477727
-
Bioengineering lactic acid bacteria to secrete the HIV-1 virucide cyanovirin
-
Pusch O, Boden D, Hannify S, et al. Bioengineering lactic acid bacteria to secrete the HIV-1 virucide cyanovirin. JAIDS 2005; 40(5): 512-20.
-
(2005)
JAIDS
, vol.40
, Issue.5
, pp. 512-520
-
-
Pusch, O.1
Boden, D.2
Hannify, S.3
-
64
-
-
33749532310
-
Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N
-
Liu X, Lagenaur LA, Simpson DA, et al. Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N. Antimicrob Agents Chemother 2006; 50(10): 3250-9.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, Issue.10
, pp. 3250-3259
-
-
Liu, X.1
Lagenaur, L.A.2
Simpson, D.A.3
-
65
-
-
33748917747
-
An anti-HIV microbicide engineered in commensal bacteria: Secretion of HIV-1 fusion inhibitors by lactobacilli
-
Pusch O, Kalyanaraman R, Tucker LD, et al. An anti-HIV microbicide engineered in commensal bacteria: secretion of HIV-1 fusion inhibitors by lactobacilli. AIDS 2006; 20(15): 1917-22.
-
(2006)
AIDS
, vol.20
, Issue.15
, pp. 1917-1922
-
-
Pusch, O.1
Kalyanaraman, R.2
Tucker, L.D.3
-
66
-
-
33845408482
-
Activity of HIV entry and fusion inhibitors expressed by the human vaginal colonizing probiotic Lactobacillus reuteri RC-14
-
Liu JJ, Reid G, Jiang Y, Turner MS, Tsai CC. Activity of HIV entry and fusion inhibitors expressed by the human vaginal colonizing probiotic Lactobacillus reuteri RC-14. Cell Microbiol 2007; 9(1): 120-30.
-
(2007)
Cell Microbiol
, vol.9
, Issue.1
, pp. 120-130
-
-
Liu, J.J.1
Reid, G.2
Jiang, Y.3
Turner, M.S.4
Tsai, C.C.5
-
67
-
-
77953626087
-
Plasmid transduction using bacteriophage Phi(adh) for expression of CC chemokines by Lactobacillus gasseri ADH
-
Damelin LH, Mavri-Damelin D, Klaenhammer TR, Tiemessen CT. Plasmid transduction using bacteriophage Phi(adh) for expression of CC chemokines by Lactobacillus gasseri ADH. Appl Environ Microbiol 2010; 76(12): 3878-85.
-
(2010)
Appl Environ Microbiol
, vol.76
, Issue.12
, pp. 3878-3885
-
-
Damelin, L.H.1
Mavri-Damelin, D.2
Klaenhammer, T.R.3
Tiemessen, C.T.4
-
68
-
-
77953756392
-
Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers
-
Vangelista L, Secchi M, Liu X, et al. Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers. Antimicrob Agents Chemother 2010; 54(7): 2994-3001.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.7
, pp. 2994-3001
-
-
Vangelista, L.1
Secchi, M.2
Liu, X.3
-
69
-
-
0032546844
-
The HIV-1 envelope glycoproteins: Fusogens, antigens, and immunogens
-
Wyatt R, Sodroski J. The HIV-1 envelope glycoproteins: fusogens, antigens, and immunogens. Science 1998; 280(5): 1884-8.
-
(1998)
Science
, vol.280
, Issue.5
, pp. 1884-1888
-
-
Wyatt, R.1
Sodroski, J.2
-
70
-
-
0034924823
-
Mechanisms of viral membrane fusion and its inhibition
-
Eckert DM, Kim PS. Mechanisms of viral membrane fusion and its inhibition. AnnuRev Biochem 2001; 70(34): 777-810.
-
(2001)
AnnuRev Biochem
, vol.70
, Issue.34
, pp. 777-810
-
-
Eckert, D.M.1
Kim, P.S.2
-
72
-
-
32544446940
-
HIV and the chemokine system: 10 years later
-
Lusso P. HIV and the chemokine system: 10 years later. EMBOJ 2006; 25(3): 447-56.
-
(2006)
EMBOJ
, vol.25
, Issue.3
, pp. 447-456
-
-
Lusso, P.1
-
73
-
-
0042924181
-
Virus entry as a target for anti-HIV intervention
-
Este JA. Virus entry as a target for anti-HIV intervention. Curr Medic Chem 2003; 10: 1617-32.
-
(2003)
Curr Medic Chem
, vol.10
, pp. 1617-1632
-
-
Este, J.A.1
-
74
-
-
0036066762
-
The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults
-
Kilby JM, Lalezari JP, Eron JJ, et al. The safety, plasma pharmacokinetics, and antiviral activity of subcutaneous enfuvirtide (T-20), a peptide inhibitor of gp41-mediated virus fusion, in HIV-infected adults. AIDS Res Hum Retroviruses 2003; 18(10): 685-93.
-
(2003)
AIDS Res Hum Retroviruses
, vol.18
, Issue.10
, pp. 685-693
-
-
Kilby, J.M.1
Lalezari, J.P.2
Eron, J.J.3
-
75
-
-
3042799382
-
Prospects of HIV-1 entry inhibitors as novel therapeutics
-
Pierson TC, Doms RW, Pohlmann S. Prospects of HIV-1 entry inhibitors as novel therapeutics. Rev Med Virol 2004; 14(65): 255-70.
-
(2004)
Rev Med Virol
, vol.14
, Issue.65
, pp. 255-270
-
-
Pierson, T.C.1
Doms, R.W.2
Pohlmann, S.3
-
76
-
-
0031812844
-
The acquisition of host-encoded proteins by nascent HIV-I
-
Tremblay MJ, Fortin JF, Cantin R. The acquisition of host-encoded proteins by nascent HIV-I. Immunol Today 1998; 19(1): 346-51.
-
(1998)
Immunol Today
, vol.19
, Issue.1
, pp. 346-351
-
-
Tremblay, M.J.1
Fortin, J.F.2
Cantin, R.3
-
77
-
-
39449098115
-
HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells
-
Arthos J, Cicala C, Martinelli E, et al. HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells. Nat Immunol 2008; 9(3): 301-9.
-
(2008)
Nat Immunol
, vol.9
, Issue.3
, pp. 301-309
-
-
Arthos, J.1
Cicala, C.2
Martinelli, E.3
-
78
-
-
0025797011
-
The human vagina: Normal flora considered as an in situ tissue-associated, adherent biofilm
-
Domingue PA. The human vagina: normal flora considered as an in situ tissue-associated, adherent biofilm. Genitourin Med 1991; 67(3): 226-31.
-
(1991)
Genitourin Med
, vol.67
, Issue.3
, pp. 226-231
-
-
Domingue, P.A.1
-
79
-
-
84872146138
-
Twice-daily application of HIV microbicides alter the vaginal microbiota
-
e00370-12
-
Ravel J, Gajer P, Fu L, et al. Twice-daily application of HIV microbicides alter the vaginal microbiota. M Bio 2012; 3(6): e00370-12.
-
(2012)
M Bio
, vol.3
, Issue.6
-
-
Ravel, J.1
Gajer, P.2
Fu, L.3
-
80
-
-
0034817210
-
Origins of vaginal acidity: High D/L lactate ratio is consistent with bacteria being the primary source
-
Boskey ER Cone RA, Whaley KJ, Moench TR. Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source. Hum Reprod 2001; 16(9): 1809-13.
-
(2001)
Hum Reprod
, vol.16
, Issue.9
, pp. 1809-1813
-
-
Boskey, E.R.1
Cone, R.A.2
Whaley, K.J.3
Moench, T.R.4
-
81
-
-
0029954970
-
Hydrogen peroxide-producing lactobacilli and acquisition of vaginal infections
-
Hawes SE. Hydrogen peroxide-producing lactobacilli and acquisition of vaginal infections. J Infect Dis 1996; 174(5): 1058-63.
-
(1996)
J Infect Dis
, vol.174
, Issue.5
, pp. 1058-1063
-
-
Hawes, S.E.1
-
82
-
-
0032710330
-
Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition
-
Martin HL, Richardson BA, Nyange PM, et al. Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition. J Infect Dis 1999; 180(6): 1863-8.
-
(1999)
J Infect Dis
, vol.180
, Issue.6
, pp. 1863-1868
-
-
Martin, H.L.1
Richardson, B.A.2
Nyange, P.M.3
-
83
-
-
0032954857
-
HIV infection and disturbances of vaginal flora during pregnancy
-
Taha TE, Gray RH, Kumwenda NI, et al. HIV infection and disturbances of vaginal flora during pregnancy. J AIDS 1999; 20(1): 52-9.
-
(1999)
J AIDS
, vol.20
, Issue.1
, pp. 52-59
-
-
Taha, T.E.1
Gray, R.H.2
Kumwenda, N.I.3
-
84
-
-
24644446235
-
Toward a live microbial microbicide for HIV: Commensal bacteria secreting an HIV fusion inhibitor peptide
-
Rao S, Hu S, McHugh, et al. Toward a live microbial microbicide for HIV: commensal bacteria secreting an HIV fusion inhibitor peptide. Proc Natl Acad Sci USA 2005; 102(34): 11993-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.34
, pp. 11993-11998
-
-
Rao, S.1
Hu, S.2
McHugh3
-
85
-
-
68349150945
-
Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys
-
Johnson PR, Schnepp BC, Zhang J, et al. Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat Med 2009; 15(8): 901-6.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 901-906
-
-
Johnson, P.R.1
Schnepp, B.C.2
Zhang, J.3
-
86
-
-
84855466746
-
Antibody-based protection against HIV infection by vectored immunoprophylaxis
-
Balazs AB, et al. Antibody-based protection against HIV infection by vectored immunoprophylaxis. Nature 2012; 481(7379): 81-4.
-
(2012)
Nature
, vol.481
, Issue.7379
, pp. 81-84
-
-
Balazs, A.B.1
-
87
-
-
80054844916
-
Anti-gp120 minibody gene transfer to female genital epithelial cells protects against HIV-1 virus challenge in vitro
-
Abdel-Motal UM, Sarkis PT, Han T, et al. Anti-gp120 minibody gene transfer to female genital epithelial cells protects against HIV-1 virus challenge in vitro. PLoS One 2011; 6(10): e26473.
-
(2011)
PLoS One
, vol.6
, Issue.10
-
-
Abdel-Motal, U.M.1
Sarkis, P.T.2
Han, T.3
-
88
-
-
1642381854
-
Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines
-
Belyakov IM, Berzofsky JA. Immunobiology of mucosal HIV infection and the basis for development of a new generation of mucosal AIDS vaccines. Immunity 2004; 20: 247-53.
-
(2004)
Immunity
, vol.20
, pp. 247-253
-
-
Belyakov, I.M.1
Berzofsky, J.A.2
-
89
-
-
70450064812
-
Mucosal immunity: Induction, dissemination, and effector functions
-
Brandtzaeg P, Mucosal immunity: induction, dissemination, and effector functions. Scand J Immunol 2009; 70(6): 505-15.
-
(2009)
Scand J Immunol
, vol.70
, Issue.6
, pp. 505-515
-
-
Brandtzaeg, P.1
-
90
-
-
33644914168
-
Transgenic plant production of Cyanovirin-N, an HIV microbicide
-
Sexton A, Drake PM, Mahmood N, Harman SJ, Shattock RJ, Ma JK. Transgenic plant production of Cyanovirin-N, an HIV microbicide. FASEB Journal 2005; 19(14): 356-8.
-
(2005)
FASEB Journal
, vol.19
, Issue.14
, pp. 356-358
-
-
Sexton, A.1
Drake, P.M.2
Mahmood, N.3
Harman, S.J.4
Shattock, R.J.5
Ma, J.K.6
-
91
-
-
70349658093
-
Design, expression, and characterization of a multivalent, combination HIV microbicide
-
Sexton A, Harman S, Shattock RJ, Ma JK. Design, expression, and characterization of a multivalent, combination HIV microbicide. FASEB J 2009; 23(10): 3590-600.
-
(2009)
FASEB J
, vol.23
, Issue.10
, pp. 3590-3600
-
-
Sexton, A.1
Harman, S.2
Shattock, R.J.3
Ma, J.K.4
-
92
-
-
0037394318
-
Therapeutic potential of neutralizing antibodies in the treatment of HIV-1 infection
-
Stiegler G, H Katinger. Therapeutic potential of neutralizing antibodies in the treatment of HIV-1 infection. J Antimicrob Chemother 2003; 51: 757-9.
-
(2003)
J Antimicrob Chemother
, vol.51
, pp. 757-759
-
-
Stiegler, G.1
Katinger, H.2
-
93
-
-
0027985431
-
Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
-
Burton DR, Pyati J, Koduri R, et al. Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 1994; 266(5187): 1024-7.
-
(1994)
Science
, vol.266
, Issue.5187
, pp. 1024-1027
-
-
Burton, D.R.1
Pyati, J.2
Koduri, R.3
-
94
-
-
33847101745
-
Structural definition of a conserved neutralization epitope on HIV-1 gp120
-
Zhou T, Xu L, Dey B, et al. Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 2007; 445(7129): 732-7.
-
(2007)
Nature
, vol.445
, Issue.7129
, pp. 732-737
-
-
Zhou, T.1
Xu, L.2
Dey, B.3
-
95
-
-
9044241681
-
Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1
-
Trkola A, Purtscher M, Muster T, et al. Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1. J Virol 1996; 70(2): 1100-8.
-
(1996)
J Virol
, vol.70
, Issue.2
, pp. 1100-1108
-
-
Trkola, A.1
Purtscher, M.2
Muster, T.3
-
96
-
-
17944380435
-
Crystal structure of a neutralizing human IGG against HIV-1: A template for vaccine design
-
Saphire EO, Parren PW, Pantophlet R, et al. Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science 2001; 293(5532): 1155-9.
-
(2001)
Science
, vol.293
, Issue.5532
, pp. 1155-1159
-
-
Saphire, E.O.1
Parren, P.W.2
Pantophlet, R.3
-
97
-
-
0027378573
-
A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1
-
Muster T, et al. A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1. J Virol 1993; 67(11): 6642-7.
-
(1993)
J Virol
, vol.67
, Issue.11
, pp. 6642-6647
-
-
Muster, T.1
-
98
-
-
4544379899
-
Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope
-
Ofek G, Tang M, Sambor A, et al. Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope. J Virol 2004; 78(19): 10724-37.
-
(2004)
J Virol
, vol.78
, Issue.19
, pp. 10724-10737
-
-
Ofek, G.1
Tang, M.2
Sambor, A.3
-
99
-
-
0034759882
-
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41
-
Zwick MB, Labrijn AF, Wang M, et al. Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41. J Virol 2001; 75(22): 10892-905.
-
(2001)
J Virol
, vol.75
, Issue.22
, pp. 10892-10905
-
-
Zwick, M.B.1
Labrijn, A.F.2
Wang, M.3
-
100
-
-
11144227042
-
Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
-
Zwick MB, Jensen R, Church S, et al. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. J Virol 2005; 79(2): 1252-61.
-
(2005)
J Virol
, vol.79
, Issue.2
, pp. 1252-1261
-
-
Zwick, M.B.1
Jensen, R.2
Church, S.3
-
101
-
-
3843139398
-
Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti-HIV type 1 neutralizing monoclonal antibody
-
Kunert R, Wolbank S, Stiegler G, Weik R, Katinger H. Characterization of molecular features, antigen-binding, and in vitro properties of IgG and IgM variants of 4E10, an anti-HIV type 1 neutralizing monoclonal antibody. AIDS Res Hum Retroviruses 2004; 20(7): 755-62.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.7
, pp. 755-762
-
-
Kunert, R.1
Wolbank, S.2
Stiegler, G.3
Weik, R.4
Katinger, H.5
-
102
-
-
0034864776
-
Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro
-
Parren PW, Marx PA, Hessell AJ, et al. Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/human immunodeficiency virus at serum levels giving complete neutralization in vitro. J Virol 2001; 75(17): 8340-7.
-
(2001)
J Virol
, vol.75
, Issue.17
, pp. 8340-8347
-
-
Parren, P.W.1
Marx, P.A.2
Hessell, A.J.3
-
103
-
-
67249131966
-
Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
-
Hessell AJ, Rakasz EG, Poignard P, et al. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog 2009; 5(5): e1000433.
-
(2009)
PLoS Pathog
, vol.5
, Issue.5
-
-
Hessell, A.J.1
Rakasz, E.G.2
Poignard, P.3
-
104
-
-
0345471066
-
Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120
-
Veazey RS, Shattock RJ, Pope M, et al. Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120. Nat Med 2003; 9(3): 343-6.
-
(2003)
Nat Med
, vol.9
, Issue.3
, pp. 343-346
-
-
Veazey, R.S.1
Shattock, R.J.2
Pope, M.3
-
105
-
-
79960585840
-
Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody
-
Burton DR, Hessell AJ, Keele BF, et al. Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody. Proc Natl Acad Sci U S A 2011; 108(27): 11181-6.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.27
, pp. 11181-11186
-
-
Burton, D.R.1
Hessell, A.J.2
Keele, B.F.3
-
106
-
-
84870510055
-
Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice
-
Hur EM, Patel SN, Shimizu S, et al. Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice. Blood 2012; 120(23): 4571-82.
-
(2012)
Blood
, vol.120
, Issue.23
, pp. 4571-4582
-
-
Hur, E.M.1
Patel, S.N.2
Shimizu, S.3
-
107
-
-
73949154006
-
Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L
-
Hessell AJ, Rakasz EG, Tehrani DM, et al. Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L. J Virol 2010; 84(3): 1302-13.
-
(2010)
J Virol
, vol.84
, Issue.3
, pp. 1302-1313
-
-
Hessell, A.J.1
Rakasz, E.G.2
Tehrani, D.M.3
-
108
-
-
2942534479
-
Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies
-
Ferrantelli F, Rasmussen RA, Buckley KA, et al. Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies. J Infect Dis 2004; 189(12): 2167-73.
-
(2004)
J Infect Dis
, vol.189
, Issue.12
, pp. 2167-2173
-
-
Ferrantelli, F.1
Rasmussen, R.A.2
Buckley, K.A.3
-
109
-
-
84890899378
-
Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques
-
Moog C, Dereuddre-Bosquet N, Teillaud JL, et al. Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques. Mucosal Immunol 2014; 7(1): 46-56.
-
(2014)
Mucosal Immunol
, vol.7
, Issue.1
, pp. 46-56
-
-
Moog, C.1
Dereuddre-Bosquet, N.2
Teillaud, J.L.3
-
110
-
-
20944446452
-
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
-
Trkola A, Kuster H, Rusert P, et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med 2005; 11(6): 615-22.
-
(2005)
Nat Med
, vol.11
, Issue.6
, pp. 615-622
-
-
Trkola, A.1
Kuster, H.2
Rusert, P.3
-
111
-
-
0037169214
-
A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1
-
Armbruster C, Stiegler GM, Vcelar BA, et al. A phase I trial with two human monoclonal antibodies (hMAb 2F5, 2G12) against HIV-1. AIDS 2002; 16(2): 227-33.
-
(2002)
AIDS
, vol.16
, Issue.2
, pp. 227-233
-
-
Armbruster, C.1
Stiegler, G.M.2
Vcelar, B.A.3
-
112
-
-
8844219655
-
Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12
-
Armbruster C, Stiegler GM, Vcelar BA, et al. Passive immunization with the anti-HIV-1 human monoclonal antibody (hMAb) 4E10 and the hMAb combination 4E10/2F5/2G12. J Antimicrob Chemother 2004; 54(5): 915-20.
-
(2004)
J Antimicrob Chemother
, vol.54
, Issue.5
, pp. 915-920
-
-
Armbruster, C.1
Stiegler, G.M.2
Vcelar, B.A.3
-
113
-
-
63849131879
-
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals
-
Scheid JF, Mouquet H, Feldhahn N, et al. Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals. Nature 2009; 458(7238): 636-40.
-
(2009)
Nature
, vol.458
, Issue.7238
, pp. 636-640
-
-
Scheid, J.F.1
Mouquet, H.2
Feldhahn, N.3
-
114
-
-
44449118948
-
Rapid cloning of high-affinity human monoclonal antibodies against influenza virus
-
Wrammert J, Smith K, Miller J, et al. Rapid cloning of high-affinity human monoclonal antibodies against influenza virus. Nature 2008; 453(7195): 667-71.
-
(2008)
Nature
, vol.453
, Issue.7195
, pp. 667-671
-
-
Wrammert, J.1
Smith, K.2
Miller, J.3
-
115
-
-
77954920017
-
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1
-
Wu X, Yang ZY, Li Y, et al. Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science 2010; 329(5993):856-61.
-
(2010)
Science
, vol.329
, Issue.5993
, pp. 856-861
-
-
Wu, X.1
Yang, Z.Y.2
Li, Y.3
-
116
-
-
80052925616
-
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding
-
Scheid JF, Mouquet H, Ueberheide B, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science 2011; 333(6049): 1633-7.
-
(2011)
Science
, vol.333
, Issue.6049
, pp. 1633-1637
-
-
Scheid, J.F.1
Mouquet, H.2
Ueberheide, B.3
-
117
-
-
84866443327
-
Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein
-
Klein F, Gaebler C, Mouquet H, et al. Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein. J Exp Med 2012; 209(8): 1469-79.
-
(2012)
J Exp Med
, vol.209
, Issue.8
, pp. 1469-1479
-
-
Klein, F.1
Gaebler, C.2
Mouquet, H.3
-
118
-
-
77649318846
-
Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals
-
Corti D, Langedijk JP, Hinz A, et al. Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals. PLoS One 2010; 5(1): e8805.
-
(2010)
PLoS One
, vol.5
, Issue.1
-
-
Corti, D.1
Langedijk, J.P.2
Hinz, A.3
-
119
-
-
84865295305
-
Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model
-
Veselinovic M, Neff CP, Mulder LR, Akkina R. Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model. Virology 2012; 432(2): 505-10.
-
(2012)
Virology
, vol.432
, Issue.2
, pp. 505-510
-
-
Veselinovic, M.1
Neff, C.P.2
Mulder, L.R.3
Akkina, R.4
-
120
-
-
84877779790
-
Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A new model for investigating HIV-1 transmission and treatment efficacy
-
Seay K, Qi X, Zheng JH, et al. Mice Transgenic for CD4-Specific Human CD4, CCR5 and Cyclin T1 Expression: A new model for investigating HIV-1 transmission and treatment efficacy. PLoS One 2013; 8(5): e63537.
-
(2013)
PLoS One
, vol.8
, Issue.5
-
-
Seay, K.1
Qi, X.2
Zheng, J.H.3
-
121
-
-
70349887757
-
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
-
Walker LM, Phogat SK, Chan-Hui PY, et al. Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target. Science 2009; 326(5950): 285-9.
-
(2009)
Science
, vol.326
, Issue.5950
, pp. 285-289
-
-
Walker, L.M.1
Phogat, S.K.2
Chan-Hui, P.Y.3
-
122
-
-
80052938385
-
Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors
-
Bonsignori M, Hwang KK, Chen X, et al. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. J Virol 2011; 85(19): 9998-10009.
-
(2011)
J Virol
, vol.85
, Issue.19
, pp. 9998-10009
-
-
Bonsignori, M.1
Hwang, K.K.2
Chen, X.3
-
123
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, Huber M, Doores KJ, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 2011; 477(7365): 466-70.
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
-
124
-
-
0037119027
-
Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and - experienced patients
-
Xu L, Hué S, Taylor S, et al. Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and - experienced patients. AIDS 2002; 16(12): 1684-6.
-
(2002)
AIDS
, vol.16
, Issue.12
, pp. 1684-1686
-
-
Xu, L.1
Hué, S.2
Taylor, S.3
-
125
-
-
0033644748
-
Chemokine inhibition of HIV infection
-
Reeves JD, Simmons G. Chemokine inhibition of HIV infection. Methods Mol Biol 2000; 138: 209-22.
-
(2000)
Methods Mol Biol
, vol.138
, pp. 209-222
-
-
Reeves, J.D.1
Simmons, G.2
-
126
-
-
28044444334
-
Development of HIV fusion inhibitors
-
Schneider SE, Bray BL, Mader CJ, et al. Development of HIV fusion inhibitors. J Pept Sci 2005; 11(11): 744-53.
-
(2005)
J Pept Sci
, vol.11
, Issue.11
, pp. 744-753
-
-
Schneider, S.E.1
Bray, B.L.2
Mader, C.J.3
-
127
-
-
20144386372
-
T-1249 retains potent antiretroviral activity in patients who had experienced virological failure while on an enfuvirtide-containing treatment regimen
-
Lalezari JP, Bellos NC, Sathasivam K, et al. T-1249 retains potent antiretroviral activity in patients who had experienced virological failure while on an enfuvirtide-containing treatment regimen. J Infect Dis 2005; 191(7): 1155-63.
-
(2005)
J Infect Dis
, vol.191
, Issue.7
, pp. 1155-1163
-
-
Lalezari, J.P.1
Bellos, N.C.2
Sathasivam, K.3
-
128
-
-
2342550183
-
Discontinuation of the clinical development of fusion inhibitor T-1249
-
Martin-Carbonero L. Discontinuation of the clinical development of fusion inhibitor T-1249. AIDS Rev 2004; 6(1): 61.
-
(2004)
AIDS Rev
, vol.6
, Issue.1
, pp. 61
-
-
Martin-Carbonero, L.1
-
129
-
-
45549093277
-
Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor
-
He Y, Xiao Y, Song H, et al. Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor. J Biol Chem 2008; 283(17): 11126-34.
-
(2008)
J Biol Chem
, vol.283
, Issue.17
, pp. 11126-11134
-
-
He, Y.1
Xiao, Y.2
Song, H.3
-
130
-
-
0030970693
-
Core structure of gp41 from the HIV envelope glycoprotein
-
Chan DC, Fass D, Berger JM, Kim PS. Core structure of gp41 from the HIV envelope glycoprotein. Cell 1997; 89(2): 263-73.
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 263-273
-
-
Chan, D.C.1
Fass, D.2
Berger, J.M.3
Kim, P.S.4
-
131
-
-
0035949493
-
Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region
-
Eckert DM, PS. Kim. Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region. Proc Natl Acad Sci USA 2001; 98(20): 11187-92.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.20
, pp. 11187-11192
-
-
Eckert, D.M.1
Kim, P.S.2
-
132
-
-
0030979950
-
Absorption and excretion of undegradable peptides: Role of lipid solubility and net charge
-
Pappenheimer JR, Karnovsky ML, Maggio JE. Absorption and excretion of undegradable peptides: Role of lipid solubility and net charge. J Pharmacol Exp Ther 1997; 280(1): 292-300.
-
(1997)
J Pharmacol Exp Ther
, vol.280
, Issue.1
, pp. 292-300
-
-
Pappenheimer, J.R.1
Karnovsky, M.L.2
Maggio, J.E.3
-
133
-
-
77957942154
-
Design of a Potent D-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance
-
Welch BD, et al. Design of a Potent D-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance. J Virol 2010; 84(21): 11235-44.
-
(2010)
J Virol
, vol.84
, Issue.21
, pp. 11235-11244
-
-
Welch, B.D.1
-
134
-
-
0035793406
-
Protein design of an HIV-1 entry inhibitor
-
Root MJ, Kay MS, Kim PS. Protein design of an HIV-1 entry inhibitor. Science 2001; 291(5505): 884-8.
-
(2001)
Science
, vol.291
, Issue.5505
, pp. 884-888
-
-
Root, M.J.1
Kay, M.S.2
Kim, P.S.3
-
135
-
-
33748741296
-
Kinetic dependence to HIV-1 entry inhibition
-
Steger HK, MJ. Root, Kinetic dependence to HIV-1 entry inhibition. J Biol Chem 2006; 281(35): 25813-21.
-
(2006)
J Biol Chem
, vol.281
, Issue.35
, pp. 25813-25821
-
-
Steger, H.K.1
Root, M.J.2
-
136
-
-
73549091727
-
Asymmetric deactivation of HIV-1 gp41 following fusion inhibitor binding
-
Kahle KM, Steger HK, Root MJ. Asymmetric deactivation of HIV-1 gp41 following fusion inhibitor binding. PLoS Pathog 2009; 5(11): e1000674.
-
(2009)
PLoS Pathog
, vol.5
, Issue.11
-
-
Kahle, K.M.1
Steger, H.K.2
Root, M.J.3
-
137
-
-
0025794308
-
Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4
-
Daar ES, Ho DD. Relative resistance of primary HIV-1 isolates to neutralization by soluble CD4. Am J Med 1991; 90: S22-S26.
-
(1991)
Am J Med
, vol.90
-
-
Daar, E.S.1
Ho, D.D.2
-
138
-
-
49449101856
-
Engineering of a human vaginal Lactobacillus strain for surface expression of two-domain CD4 molecules
-
Liu X, Lagenaur LA, Lee PP, Xu Q. Engineering of a human vaginal Lactobacillus strain for surface expression of two-domain CD4 molecules. Appl Environ Microbiol 2008; 74(15): 4626-35.
-
(2008)
Appl Environ Microbiol
, vol.74
, Issue.15
, pp. 4626-4635
-
-
Liu, X.1
Lagenaur, L.A.2
Lee, P.P.3
Xu, Q.4
-
139
-
-
0029062687
-
Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates
-
Allaway GP, Davis-Bruno KL, Beaudry GA. Expression and characterization of CD4-IgG2, a novel heterotetramer that neutralizes primary HIV type 1 isolates. AIDS Res Hum Retroviruses 1995; 11(5): 533-9.
-
(1995)
AIDS Res Hum Retroviruses
, vol.11
, Issue.5
, pp. 533-539
-
-
Allaway, G.P.1
Davis-Bruno, K.L.2
Beaudry, G.A.3
-
140
-
-
0031936306
-
Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage
-
Trkola A, Ketas T, Kewalramani VN, et al. Neutralization sensitivity of human immunodeficiency virus type 1 primary isolates to antibodies and CD4-based reagents is independent of coreceptor usage. J Virol 1998; 72(3): 1876-85.
-
(1998)
J Virol
, vol.72
, Issue.3
, pp. 1876-1885
-
-
Trkola, A.1
Ketas, T.2
Kewalramani, V.N.3
-
141
-
-
0031900546
-
CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates
-
Gauduin MC, Allaway GP, Olson WC, Weir R, Maddon PJ, Koup RA. CD4-immunoglobulin G2 protects Hu-PBL-SCID mice against challenge by primary human immunodeficiency virus type 1 isolates. J Virol 1998; 72(4): 3475-8.
-
(1998)
J Virol
, vol.72
, Issue.4
, pp. 3475-3478
-
-
Gauduin, M.C.1
Allaway, G.P.2
Olson, W.C.3
Weir, R.4
Maddon, P.J.5
Koup, R.A.6
-
142
-
-
0033712475
-
Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: Phase 1/2 study. The Pediatric AIDS Clinical Trials Group Protocol 351 Study Team
-
Shearer WT, Israel RJ, Starr S, et al. Recombinant CD4-IgG2 in human immunodeficiency virus type 1-infected children: phase 1/2 study. The Pediatric AIDS Clinical Trials Group Protocol 351 Study Team. J Infect Dis 2000; 182(6): 1774-9.
-
(2000)
J Infect Dis
, vol.182
, Issue.6
, pp. 1774-1779
-
-
Shearer, W.T.1
Israel, R.J.2
Starr, S.3
-
143
-
-
9144250171
-
Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO542
-
Jacobson JM, Israel RJ, Lowy I, et al. Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO542. Antimicrob Agents Chemother 2004; 48(2): 423-9.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, Issue.2
, pp. 423-429
-
-
Jacobson, J.M.1
Israel, R.J.2
Lowy, I.3
-
144
-
-
84864398946
-
Protection against high-dose highly pathogenic mucosal SIV challenge at very low serum neutralizing titers of the antibodylike molecule CD4-IgG2
-
Poignard P. Protection against high-dose highly pathogenic mucosal SIV challenge at very low serum neutralizing titers of the antibodylike molecule CD4-IgG2. PLoS One 2012; 7(7): e42209.
-
(2012)
PLoS One
, vol.7
, Issue.7
-
-
Poignard, P.1
-
145
-
-
84896353107
-
Hexameric CD80 and CD86-Ig fusion proteins
-
Chaikin M. Hexameric CD80 and CD86-Ig fusion proteins. J Allergy Clin Immunol 1997; 99(1): 835-9.
-
(1997)
J Allergy Clin Immunol
, vol.99
, Issue.1
, pp. 835-839
-
-
Chaikin, M.1
-
146
-
-
0037192834
-
Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein: Implications for therapeutic and vaccine strategies
-
Arthos J, Cicala C, Steenbeke TD, et al. Biochemical and biological characterization of a dodecameric CD4-Ig fusion protein: implications for therapeutic and vaccine strategies. J Biol Chem 2002; 277(13): 11456-64.
-
(2002)
J Biol Chem
, vol.277
, Issue.13
, pp. 11456-11464
-
-
Arthos, J.1
Cicala, C.2
Steenbeke, T.D.3
-
147
-
-
0031904693
-
Novel miniproteins engineered by the transfer of active sites to small natural scaffolds
-
Vita C, Vizzavona J, Drakopoulou E, et al. Novel miniproteins engineered by the transfer of active sites to small natural scaffolds. Biopolymers 1998; 47(1): 93-100.
-
(1998)
Biopolymers
, vol.47
, Issue.1
, pp. 93-100
-
-
Vita, C.1
Vizzavona, J.2
Drakopoulou, E.3
-
148
-
-
12244281787
-
Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes
-
Martin L, Stricher F, Missé D, et al. Rational design of a CD4 mimic that inhibits HIV-1 entry and exposes cryptic neutralization epitopes. Nat Biotechnol 2003; 21(1): 71-6.
-
(2003)
Nat Biotechnol
, vol.21
, Issue.1
, pp. 71-76
-
-
Martin, L.1
Stricher, F.2
Missé, D.3
-
149
-
-
50249084524
-
Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein
-
Stricher F, Huang CC, Descours A, et al. Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein. J Mol Biol 2008; 382(2): 510-24.
-
(2008)
J Mol Biol
, vol.382
, Issue.2
, pp. 510-524
-
-
Stricher, F.1
Huang, C.C.2
Descours, A.3
-
150
-
-
41149121552
-
CD4 mimetic miniproteins: Potent anti-HIV compounds with promising activity as microbicides
-
van Herrewege Y, Morellato L, Descours A, et al. CD4 mimetic miniproteins: potent anti-HIV compounds with promising activity as microbicides. J Antimicrob Chemother 2008; 61(4): 818-26.
-
(2008)
J Antimicrob Chemother
, vol.61
, Issue.4
, pp. 818-826
-
-
van Herrewege, Y.1
Morellato, L.2
Descours, A.3
-
151
-
-
0032543307
-
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
-
Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA. Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 1998; 393(6686): 648-59.
-
(1998)
Nature
, vol.393
, Issue.6686
, pp. 648-659
-
-
Kwong, P.D.1
Wyatt, R.2
Robinson, J.3
Sweet, R.W.4
Sodroski, J.5
Hendrickson, W.A.6
-
152
-
-
20844448731
-
Antigenic conservation and immunogenicity of the HIV coreceptor binding site
-
Decker JM, Bibollet-Ruche F, Wei X, et al. Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J Exp Med 2005; 201(9): 1407-19.
-
(2005)
J Exp Med
, vol.201
, Issue.9
, pp. 1407-1419
-
-
Decker, J.M.1
Bibollet-Ruche, F.2
Wei, X.3
-
153
-
-
0037372301
-
Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor
-
Dey B, Del Castillo CS, Berger EA. Neutralization of human immunodeficiency virus type 1 by sCD4-17b, a single-chain chimeric protein, based on sequential interaction of gp120 with CD4 and coreceptor. J Virol 2003; 77(5): 2859-65.
-
(2003)
J Virol
, vol.77
, Issue.5
, pp. 2859-2865
-
-
Dey, B.1
Del Castillo, C.S.2
Berger, E.A.3
-
154
-
-
0033988632
-
Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: Soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120
-
Salzwedel K, Smith ED, Dey B, Berger EA. Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120. J Virol 2000; 74(1): 326-33.
-
(2000)
J Virol
, vol.74
, Issue.1
, pp. 326-333
-
-
Salzwedel, K.1
Smith, E.D.2
Dey, B.3
Berger, E.A.4
-
155
-
-
77949446701
-
sCD4-17b bifunctional protein: Extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates
-
Lagenaur LA, Villarroel VA, Bundoc V, Dey B, Berger EA. sCD4-17b bifunctional protein: extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates. Retrovirology 2010; 7: 11.
-
(2010)
Retrovirology
, vol.7
, pp. 11
-
-
Lagenaur, L.A.1
Villarroel, V.A.2
Bundoc, V.3
Dey, B.4
Berger, E.A.5
-
156
-
-
72849116535
-
Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents
-
West AP Jr, Galimidi RP, Foglesong CP, Gnanapragasam PN, Klein JS, Bjorkman PJ. Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents. J Virol 2010; 84(1): 261-9.
-
(2010)
J Virol
, vol.84
, Issue.1
, pp. 261-269
-
-
West Jr., A.P.1
Galimidi, R.P.2
Foglesong, C.P.3
Gnanapragasam, P.N.4
Klein, J.S.5
Bjorkman, P.J.6
-
157
-
-
77956913427
-
Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates
-
Chen W, Xiao X, Wang Y, Zhu Z, Dimitrov DS. Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates. Antiviral Res 2010; 88(1): 107-15.
-
(2010)
Antiviral Res
, vol.88
, Issue.1
, pp. 107-115
-
-
Chen, W.1
Xiao, X.2
Wang, Y.3
Zhu, Z.4
Dimitrov, D.S.5
-
158
-
-
0033525590
-
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry
-
Farzan M, Mirzabekov T, Kolchinsky P, et al. Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry. Cell 1999; 96(5): 667-76.
-
(1999)
Cell
, vol.96
, Issue.5
, pp. 667-676
-
-
Farzan, M.1
Mirzabekov, T.2
Kolchinsky, P.3
-
159
-
-
33845767989
-
Recognition of RANTES by extracellular parts of the CCR5 receptor
-
Duma L, Häussinger D, Rogowski M, Lusso P, Grzesiek S. Recognition of RANTES by extracellular parts of the CCR5 receptor. J Mol Biol 2007; 365(4): 1063-75.
-
(2007)
J Mol Biol
, vol.365
, Issue.4
, pp. 1063-1075
-
-
Duma, L.1
Häussinger, D.2
Rogowski, M.3
Lusso, P.4
Grzesiek, S.5
-
160
-
-
33745173829
-
Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1 alpha (SDF-1 alpha/CXCL12)
-
Veldkamp CT, Seibert C, Peterson FC, Sakmar TP, Volkman BF. Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1 alpha (SDF-1 alpha/CXCL12). J Mol Biol 2006; 359(5): 1400-9.
-
(2006)
J Mol Biol
, vol.359
, Issue.5
, pp. 1400-1409
-
-
Veldkamp, C.T.1
Seibert, C.2
Peterson, F.C.3
Sakmar, T.P.4
Volkman, B.F.5
-
161
-
-
0034705106
-
Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120
-
Cormier EG, Persuh M, Thompson DA, et al. Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120. Proc Natl Acad Sci U S A 2000; 97(11): 5762-7.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.11
, pp. 5762-5767
-
-
Cormier, E.G.1
Persuh, M.2
Thompson, D.A.3
-
162
-
-
34848868199
-
Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
-
Huang CC, Lam SN, Acharya P, et al. Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science 2007; 317(5846): 1930-4.
-
(2007)
Science
, vol.317
, Issue.5846
, pp. 1930-1934
-
-
Huang, C.C.1
Lam, S.N.2
Acharya, P.3
-
163
-
-
0034721834
-
A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry
-
Farzan M, Vasilieva N, Schnitzler CE, et al. A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry. J Biol Chem 2000; 275(43): 33516-21.
-
(2000)
J Biol Chem
, vol.275
, Issue.43
, pp. 33516-33521
-
-
Farzan, M.1
Vasilieva, N.2
Schnitzler, C.E.3
-
164
-
-
33749410635
-
A tyrosine-sulfated peptide derived from the heavy-chain CDR3 region of an HIV-1-neutralizing antibody binds gp120 and inhibits HIV-1 infection
-
Dorfman T, Moore MJ, Guth AC, Choe H, Farzan M. A tyrosine-sulfated peptide derived from the heavy-chain CDR3 region of an HIV-1-neutralizing antibody binds gp120 and inhibits HIV-1 infection. J Biol Chem 2006; 281(39): 28529-35.
-
(2006)
J Biol Chem
, vol.281
, Issue.39
, pp. 28529-28535
-
-
Dorfman, T.1
Moore, M.J.2
Guth, A.C.3
Choe, H.4
Farzan, M.5
-
165
-
-
79960343575
-
The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide
-
Schnur E, Noah E, Ayzenshtat I, et al. The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide. J Mol Biol 2011; 410(5): 778-97.
-
(2011)
J Mol Biol
, vol.410
, Issue.5
, pp. 778-797
-
-
Schnur, E.1
Noah, E.2
Ayzenshtat, I.3
-
166
-
-
84869106867
-
Enhanced recognition and neutralization of HIV-1 by antibody-derived CCR5-mimetic peptide variants
-
Chiang JJ, Gardner MR, Quinlan BD, Dorfman T, Choe H, Farzan M. Enhanced recognition and neutralization of HIV-1 by antibody-derived CCR5-mimetic peptide variants. J Virol 2012; 86(22): 12417-21.
-
(2012)
J Virol
, vol.86
, Issue.22
, pp. 12417-12421
-
-
Chiang, J.J.1
Gardner, M.R.2
Quinlan, B.D.3
Dorfman, T.4
Choe, H.5
Farzan, M.6
-
167
-
-
0842264042
-
Specific inhibition of HIV-1 coreceptor activity by synthetic peptides corresponding to the predicted extracellular loops of CCR5
-
Agrawal L, VanHorn-Ali Z, Berger EA, Alkhatib G. Specific inhibition of HIV-1 coreceptor activity by synthetic peptides corresponding to the predicted extracellular loops of CCR5. Blood 2004; 103(4): 1211-7.
-
(2004)
Blood
, vol.103
, Issue.4
, pp. 1211-1217
-
-
Agrawal, L.1
Vanhorn-Ali, Z.2
Berger, E.A.3
Alkhatib, G.4
-
168
-
-
84860357305
-
Peptides from second extracellular loop of C-C chemokine receptor type 5 (CCR5) inhibit diverse strains of HIV-1
-
Dogo-Isonagie C, Lam S, Gustchina E, et al. Peptides from second extracellular loop of C-C chemokine receptor type 5 (CCR5) inhibit diverse strains of HIV-1. J Biol Chem 2012; 287(18): 15076-86.
-
(2012)
J Biol Chem
, vol.287
, Issue.18
, pp. 15076-15086
-
-
Dogo-Isonagie, C.1
Lam, S.2
Gustchina, E.3
-
169
-
-
84881255827
-
Lack of prophylactic efficacy of oral maraviroc in macaques despite high drug concentrations in rectal tissues
-
Massud I, Aung W, Martin A, et al. Lack of prophylactic efficacy of oral maraviroc in macaques despite high drug concentrations in rectal tissues. J Virol 2013; 87(16): 8952-61.
-
(2013)
J Virol
, vol.87
, Issue.16
, pp. 8952-8961
-
-
Massud, I.1
Aung, W.2
Martin, A.3
-
170
-
-
77957349209
-
Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-infected Adults
-
Jacobson JM, Lalezari JP, Thompson MA, et al. Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-infected Adults. Antimicrob Agents Chemother 2010; 54(10): 4137-42.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, Issue.10
, pp. 4137-4142
-
-
Jacobson, J.M.1
Lalezari, J.P.2
Thompson, M.A.3
-
171
-
-
79960455651
-
Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4
-
Burastero SE, Frigerio B, Lopalco L, et al. Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4. PLoS One 2011; 6(7): e22081.
-
(2011)
PLoS One
, vol.6
, Issue.7
-
-
Burastero, S.E.1
Frigerio, B.2
Lopalco, L.3
-
172
-
-
9344239350
-
Medicinal chemistry applied to a synthetic protein: Development of highly potent HIV entry inhibitors
-
Hartley O, Gaertner H, Wilken J, et al. Medicinal chemistry applied to a synthetic protein: Development of highly potent HIV entry inhibitors. Proc Natl Acad Sci USA 2004; 101(47): 16460-5.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.47
, pp. 16460-16465
-
-
Hartley, O.1
Gaertner, H.2
Wilken, J.3
-
173
-
-
0033746503
-
Enhancement of the HIV-1 inhibitory activity of RANTES by modification of the N-terminal region: Dissociation from CCR5 activation
-
Polo S, Nardese V, De Santis C, et al. Enhancement of the HIV-1 inhibitory activity of RANTES by modification of the N-terminal region: dissociation from CCR5 activation. Eur J Immunol 2000; 30(11): 3190-8.
-
(2000)
Eur J Immunol
, vol.30
, Issue.11
, pp. 3190-3198
-
-
Polo, S.1
Nardese, V.2
de Santis, C.3
-
174
-
-
44649200690
-
Lusso, Rational design of novel HIV-1 entry inhibitors by RANTES engineering
-
Vangelista L. M. Secchi, P Lusso, Rational design of novel HIV-1 entry inhibitors by RANTES engineering. Vaccine 2008; 26(24): 3008-5.
-
(2008)
Vaccine
, vol.26
, Issue.24
, pp. 3008-3015
-
-
Vangelista, L.M.1
Secchi, P.2
-
175
-
-
77449148552
-
Structural and functional studies of the potent anti-HIV chemokine variant P2-RANTES
-
Jin H, Kagiampakis I, Li P, Liwang PJ. Structural and functional studies of the potent anti-HIV chemokine variant P2-RANTES. Proteins 2010; 78(2): 295-308.
-
(2010)
Proteins
, vol.78
, Issue.2
, pp. 295-308
-
-
Jin, H.1
Kagiampakis, I.2
Li, P.3
Liwang, P.J.4
-
176
-
-
77956406053
-
Development of an HIV-1 specific microbicide using Caulobacter crescentus S-layer mediated display of CD4 and MIP1alpha
-
Nomellini JF, Li C, Lavallee D, et al. Development of an HIV-1 specific microbicide using Caulobacter crescentus S-layer mediated display of CD4 and MIP1alpha. PLoS One 2010; 5(4): e10366.
-
(2010)
PLoS One
, vol.5
, Issue.4
-
-
Nomellini, J.F.1
Li, C.2
Lavallee, D.3
-
177
-
-
0034958336
-
Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES
-
Nardese V, Longhi R, Polo S, et al. Structural determinants of CCR5 recognition and HIV-1 blockade in RANTES. Nat Struct Biol 2001; 8(7): 611-5.
-
(2001)
Nat Struct Biol
, vol.8
, Issue.7
, pp. 611-615
-
-
Nardese, V.1
Longhi, R.2
Polo, S.3
-
178
-
-
79954597305
-
Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity
-
Lusso P, Vangelista L, Cimbro R, et al. Molecular engineering of RANTES peptide mimetics with potent anti-HIV-1 activity. FASEB J 2011; 25(4): 1230-43.
-
(2011)
FASEB J
, vol.25
, Issue.4
, pp. 1230-1243
-
-
Lusso, P.1
Vangelista, L.2
Cimbro, R.3
-
179
-
-
84871569866
-
Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides
-
Secchi M, Longhi R, Vassena L, et al. Enhancement of anti-HIV-1 activity by hot spot evolution of RANTES-derived peptides. Chem Biol 2012; 19(12): 1579-88.
-
(2012)
Chem Biol
, vol.19
, Issue.12
, pp. 1579-1588
-
-
Secchi, M.1
Longhi, R.2
Vassena, L.3
-
180
-
-
0032902710
-
Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5
-
Olson WC, Rabut GE, Nagashima KA, et al. Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5. J Virol 1999; 73(5): 4145-55.
-
(1999)
J Virol
, vol.73
, Issue.5
, pp. 4145-4155
-
-
Olson, W.C.1
Rabut, G.E.2
Nagashima, K.A.3
-
182
-
-
40549092975
-
Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients
-
Lalezari J, Yadavalli GK, Para M, et al. Safety, pharmacokinetics, and antiviral activity of HGS004, a novel fully human IgG4 monoclonal antibody against CCR5, in HIV-1-infected patients. J Infect Dis 2008; 197(5): 721-7.
-
(2008)
J Infect Dis
, vol.197
, Issue.5
, pp. 721-727
-
-
Lalezari, J.1
Yadavalli, G.K.2
Para, M.3
-
183
-
-
79251555316
-
Blocking of alpha4beta7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques
-
Ansari AA, Reimann KA, Mayne AE, et al. Blocking of alpha4beta7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J Immunol 2011; 186(2): 1044-59.
-
(2011)
J Immunol
, vol.186
, Issue.2
, pp. 1044-1059
-
-
Ansari, A.A.1
Reimann, K.A.2
Mayne, A.E.3
-
184
-
-
79952232940
-
The genotype of early-transmitting HIV gp120s promotes alpha (4) beta(7)-reactivity, revealing alpha (4) beta(7) +/CD4+ T cells as key targets in mucosal transmission
-
Nawaz F, Cicala C, van Ryk D, et al. The genotype of early-transmitting HIV gp120s promotes alpha (4) beta(7)-reactivity, revealing alpha (4) beta(7) +/CD4+ T cells as key targets in mucosal transmission. PLoS Pathog 2011; 7(2): e1001301.
-
(2011)
PLoS Pathog
, vol.7
, Issue.2
-
-
Nawaz, F.1
Cicala, C.2
van Ryk, D.3
-
185
-
-
0032543555
-
The antigenic structure of the HIV gp120 envelope glycoprotein
-
Wyatt R, Kwong PD, Desjardins E, et al. The antigenic structure of the HIV gp120 envelope glycoprotein. Nature 1998; 393(6686): 705-11.
-
(1998)
Nature
, vol.393
, Issue.6686
, pp. 705-711
-
-
Wyatt, R.1
Kwong, P.D.2
Desjardins, E.3
-
186
-
-
84863115983
-
High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection
-
Lavine CL, et al. High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection. J Virol 2012; 86(4): 2153-64.
-
(2012)
J Virol
, vol.86
, Issue.4
, pp. 2153-2164
-
-
Lavine, C.L.1
-
187
-
-
0034598934
-
Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses
-
Geijtenbeek TB, Torensma R, van Vliet SJ, et al. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 2000; 100(5): 575-85.
-
(2000)
Cell
, vol.100
, Issue.5
, pp. 575-585
-
-
Geijtenbeek, T.B.1
Torensma, R.2
van Vliet, S.J.3
-
188
-
-
0035033755
-
DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus
-
Pöhlmann S, Baribaud F, Lee B, et al. DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. J Virol 2001; 75(10): 4664-72.
-
(2001)
J Virol
, vol.75
, Issue.10
, pp. 4664-4672
-
-
Pöhlmann, S.1
Baribaud, F.2
Lee, B.3
-
189
-
-
0035980040
-
Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts
-
Mummidi S, Catano G, Lam L, et al. Extensive repertoire of membrane-bound and soluble dendritic cell-specific ICAM-3-grabbing nonintegrin 1 (DC-SIGN1) and DC-SIGN2 isoforms. Inter-individual variation in expression of DC-SIGN transcripts. J Biol Chem 2001; 276(35): 33196-212.
-
(2001)
J Biol Chem
, vol.276
, Issue.35
, pp. 33196-33212
-
-
Mummidi, S.1
Catano, G.2
Lam, L.3
-
190
-
-
0035800757
-
A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR. Subunit organization and binding to multivalent ligands
-
Mitchell DA, Fadden AJ, Drickamer K. A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR. Subunit organization and binding to multivalent ligands. J Biol Chem 2001; 276(31): 28939-45.
-
(2001)
J Biol Chem
, vol.276
, Issue.31
, pp. 28939-28945
-
-
Mitchell, D.A.1
Fadden, A.J.2
Drickamer, K.3
-
191
-
-
82855163961
-
DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4
-
Hijazi K, Wang Y, Scala C, et al. DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4. PLoS One 2011; 6(12): e28307.
-
(2011)
PLoS One
, vol.6
, Issue.12
-
-
Hijazi, K.1
Wang, Y.2
Scala, C.3
-
192
-
-
84865407002
-
Bifunctional CD4-DC-SIGN fusion proteins demonstrate enhanced avidity to gp120 and inhibit HIV-1 infection and dissemination
-
Du T, Hu K, Yang J, et al. Bifunctional CD4-DC-SIGN fusion proteins demonstrate enhanced avidity to gp120 and inhibit HIV-1 infection and dissemination. Antimicrob Agents Chemother 2012; 56(9): 4640-9.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, Issue.9
, pp. 4640-4649
-
-
Du, T.1
Hu, K.2
Yang, J.3
-
193
-
-
42049112172
-
An intercellular adhesion molecule-3 (ICAM-3)-grabbing nonintegrin (DC-SIGN) efficiently blocks HIV viral budding
-
Wang Q, Pang S. An intercellular adhesion molecule-3 (ICAM-3)-grabbing nonintegrin (DC-SIGN) efficiently blocks HIV viral budding. FASEB J 2008; 22(4): 1055-64.
-
(2008)
FASEB J
, vol.22
, Issue.4
, pp. 1055-1064
-
-
Wang, Q.1
Pang, S.2
-
194
-
-
0034843054
-
Bitter-sweet symphony: Defining the role of dendritic cell gp120 receptors in HIV infection
-
Turville SG, Cameron PU, Arthos J, et al. Bitter-sweet symphony: defining the role of dendritic cell gp120 receptors in HIV infection. J Clin Virol 2001; 22(3): 229-39.
-
(2001)
J Clin Virol
, vol.22
, Issue.3
, pp. 229-239
-
-
Turville, S.G.1
Cameron, P.U.2
Arthos, J.3
-
195
-
-
49049090124
-
C-type lectin Mermaid inhibits dendritic cell mediated HIV-1 transmission to CD4+ T cells
-
Nabatov AA, de Jong MA, de Witte L, Bulgheresi S, Geijtenbeek TB, et al. C-type lectin Mermaid inhibits dendritic cell mediated HIV-1 transmission to CD4+ T cells. Virology 2008; 378(2): 323-8.
-
(2008)
Virology
, vol.378
, Issue.2
, pp. 323-328
-
-
Nabatov, A.A.1
de Jong, M.A.2
de Witte, L.3
Bulgheresi, S.4
Geijtenbeek, T.B.5
-
196
-
-
0030790094
-
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: Potential applications to microbicide development
-
Boyd MR, Gustafson KR, McMahon JB, et al. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob Agents Chemother 1997; 41(7): 1521-30.
-
(1997)
Antimicrob Agents Chemother
, vol.41
, Issue.7
, pp. 1521-1530
-
-
Boyd, M.R.1
Gustafson, K.R.2
McMahon, J.B.3
-
197
-
-
0031559765
-
Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum
-
Gustafson KR, Sowder RC II, Henderson LE, et al. Isolation, primary sequence determination, and disulfide bond structure of cyanovirin-N, an anti-HIV (human immunodeficiency virus) protein from the cyanobacterium Nostoc ellipsosporum. Biochem Biophys Res Commun 1997; 238(1): 223-8.
-
(1997)
Biochem Biophys Res Commun
, vol.238
, Issue.1
, pp. 223-228
-
-
Gustafson, K.R.1
Sowder II, R.C.2
Henderson, L.E.3
-
198
-
-
0035040784
-
Selective interactions of the human immunodeficiency virus-inactivating protein cyanovirin-N with high-mannose oligosaccharides on gp120 and other glycoproteins
-
Shenoy SR, O'Keefe BR, Bolmstedt AJ, Cartner LK, Boyd MR. Selective interactions of the human immunodeficiency virus-inactivating protein cyanovirin-N with high-mannose oligosaccharides on gp120 and other glycoproteins. J Pharmacol Exp Ther 2001; 297(2): 704-10.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, Issue.2
, pp. 704-710
-
-
Shenoy, S.R.1
O'Keefe, B.R.2
Bolmstedt, A.J.3
Cartner, L.K.4
Boyd, M.R.5
-
199
-
-
0035028207
-
Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner
-
Bolmstedt AJ, O'Keefe BR, Shenoy SR, McMahon JB, Boyd MR. Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner. Mol Pharmacol 2001; 59(5): 949-54.
-
(2001)
Mol Pharmacol
, vol.59
, Issue.5
, pp. 949-954
-
-
Bolmstedt, A.J.1
O'Keefe, B.R.2
Shenoy, S.R.3
McMahon, J.B.4
Boyd, M.R.5
-
200
-
-
0034799906
-
The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man (8) D1D3 and Man (9) with nanomolar affinity: Implications for binding to the HIV envelope protein gp120
-
Bewley CA, Otero-Quintero S. The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man (8) D1D3 and Man (9) with nanomolar affinity: implications for binding to the HIV envelope protein gp120. J Am Chem Soc 2001; 123(17): 3892-902.
-
(2001)
J Am Chem Soc
, vol.123
, Issue.17
, pp. 3892-3902
-
-
Bewley, C.A.1
Otero-Quintero, S.2
-
201
-
-
0032921247
-
Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120
-
Esser MT, Mori T, Mondor I, et al. Cyanovirin-N binds to gp120 to interfere with CD4-dependent human immunodeficiency virus type 1 virion binding, fusion, and infectivity but does not affect the CD4 binding site on gp120 or soluble CD4-induced conformational changes in gp120. J Virol 1999; 73(5): 4360-71.
-
(1999)
J Virol
, vol.73
, Issue.5
, pp. 4360-4371
-
-
Esser, M.T.1
Mori, T.2
Mondor, I.3
-
202
-
-
0033997468
-
Multiple antiviral activities of cyanovirin-N: Blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses
-
Dey B, Lerner DL, Lusso P, Boyd MR, Elder JH, Berger EA. Multiple antiviral activities of cyanovirin-N: blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped viruses. J Virol 2000; 74(10): 4562-9.
-
(2000)
J Virol
, vol.74
, Issue.10
, pp. 4562-4569
-
-
Dey, B.1
Lerner, D.L.2
Lusso, P.3
Boyd, M.R.4
Elder, J.H.5
Berger, E.A.6
-
203
-
-
0037024754
-
The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1
-
Giomarelli B, Provvedi R, Meacci F, et al. The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1. AIDS 2002; 16(10): 1351-6.
-
(2002)
AIDS
, vol.16
, Issue.10
, pp. 1351-1356
-
-
Giomarelli, B.1
Provvedi, R.2
Meacci, F.3
-
204
-
-
20144370949
-
Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp
-
Mori T, O'Keefe BR, Sowder RC II, et al. Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp. J Biol Chem 2005; 280(10): 9345-53.
-
(2005)
J Biol Chem
, vol.280
, Issue.10
, pp. 9345-9353
-
-
Mori, T.1
O'Keefe, B.R.2
Sowder II, R.C.3
-
205
-
-
80052936296
-
Removal of two high-mannose N-linked glycans on gp120 renders human immunodeficiency virus 1 largely resistant to the carbohydrate-binding agent griffithsin
-
Huang X, Jin W, Griffin GE, Shattock RJ, Hu Q. Removal of two high-mannose N-linked glycans on gp120 renders human immunodeficiency virus 1 largely resistant to the carbohydrate-binding agent griffithsin. J Gen Virol 2011; 92(Pt 10): 2367-73.
-
(2011)
J Gen Virol
, vol.92
, Issue.PART 10
, pp. 2367-2373
-
-
Huang, X.1
Jin, W.2
Griffin, G.E.3
Shattock, R.J.4
Hu, Q.5
-
206
-
-
34547109661
-
Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide
-
Emau P, Tian B, O'keefe BR, et al. Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide. J Med Primatol 2007; 36(4-5): 244-53.
-
(2007)
J Med Primatol
, vol.36
, Issue.4-5
, pp. 244-253
-
-
Emau, P.1
Tian, B.2
O'Keefe, B.R.3
-
208
-
-
0346034962
-
A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium
-
Bokesch HR, O'Keefe BR, McKee TC, et al. A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium. Biochemistry 2003; 42(9): 2578-84.
-
(2003)
Biochemistry
, vol.42
, Issue.9
, pp. 2578-2584
-
-
Bokesch, H.R.1
O'Keefe, B.R.2
McKee, T.C.3
-
209
-
-
33745034288
-
Potent anti-HIV activity of scytovirin domain 1 peptide
-
Xiong C, O'Keefe BR, Byrd RA, McMahon JB. Potent anti-HIV activity of scytovirin domain 1 peptide. Peptides 2006; 27(7): 1668-75.
-
(2006)
Peptides
, vol.27
, Issue.7
, pp. 1668-1675
-
-
Xiong, C.1
O'Keefe, B.R.2
Byrd, R.A.3
McMahon, J.B.4
-
210
-
-
84855816891
-
The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells
-
Alexandre KB, Gray ES, Mufhandu H, et al. The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells. Virology 2012; 423(2): 175-86.
-
(2012)
Virology
, vol.423
, Issue.2
, pp. 175-186
-
-
Alexandre, K.B.1
Gray, E.S.2
Mufhandu, H.3
-
211
-
-
77955288365
-
Microvirin, a novel {alpha}(1,2)-mannose-specific lectin isolated from microcystis aeruginosa, has comparable anti-HIV-1 activity as cyanovirin-N, but a much higher safety profile
-
Huskens D, Férir G, Vermeire K, et al. Microvirin, a novel {alpha}(1,2)-mannose-specific lectin isolated from microcystis aeruginosa, has comparable anti-HIV-1 activity as cyanovirin-N, but a much higher safety profile. J Biol Chem 2010; 285(32): 24845-54.
-
(2010)
J Biol Chem
, vol.285
, Issue.32
, pp. 24845-24854
-
-
Huskens, D.1
Férir, G.2
Vermeire, K.3
-
212
-
-
79958009424
-
Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity
-
Shahzad-ul-Hussan S, Gustchina E, Ghirlando R, Clore GM, Bewley CA. Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity. J Biol Chem 2011; 286(23): 20788-96.
-
(2011)
J Biol Chem
, vol.286
, Issue.23
, pp. 20788-20796
-
-
Shahzad-ul-Hussan, S.1
Gustchina, E.2
Ghirlando, R.3
Clore, G.M.4
Bewley, C.A.5
-
213
-
-
0025672675
-
Isolation and characterization of BanLec-I, a mannoside-binding lectin from Musa paradisiac (banana)
-
Koshte VL, van Dijk W, van der Stelt ME, Aalberse RC. Isolation and characterization of BanLec-I, a mannoside-binding lectin from Musa paradisiac (banana). Biochem J 1990; 272(3): 721-6.
-
(1990)
Biochem J
, vol.272
, Issue.3
, pp. 721-726
-
-
Koshte, V.L.1
van Dijk, W.2
van der Stelt, M.E.3
Aalberse, R.C.4
-
214
-
-
77950581739
-
A lectin isolated from bananas is a potent inhibitor of HIV replication
-
Swanson MD, Winter HC, Goldstein IJ, Markovitz DM. A lectin isolated from bananas is a potent inhibitor of HIV replication. J Biol Chem 2010; 285(12): 8646-55.
-
(2010)
J Biol Chem
, vol.285
, Issue.12
, pp. 8646-8655
-
-
Swanson, M.D.1
Winter, H.C.2
Goldstein, I.J.3
Markovitz, D.M.4
-
215
-
-
4444246692
-
Primate defensins
-
Lehrer RI. Primate defensins. Nat Rev Microbiol 2004; 2(9): 727-38.
-
(2004)
Nat Rev Microbiol
, vol.2
, Issue.9
, pp. 727-738
-
-
Lehrer, R.I.1
-
216
-
-
9144240994
-
Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication
-
Quiñones-Mateu ME, Lederman MM, Feng Z, et al. Human epithelial beta-defensins 2 and 3 inhibit HIV-1 replication. AIDS 2003; 17(16): F39-F48.
-
(2003)
AIDS
, vol.17
, Issue.16
-
-
Quiñones-Mateu, M.E.1
Lederman, M.M.2
Feng, Z.3
-
217
-
-
77955439037
-
Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms
-
Seidel A, Ye Y, de Armas LR, et al. Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms. PLoSOne 2010; 5(3); e9737.
-
(2010)
PLoSOne
, vol.5
, Issue.3
-
-
Seidel, A.1
Ye, Y.2
de Armas, L.R.3
-
219
-
-
17444436038
-
The theta-defensin, retrocyclin, inhibits HIV-1 entry
-
Münk C, Wei G, Yang OO, et al. The theta-defensin, retrocyclin, inhibits HIV-1 entry. AIDS Res Hum Retroviruses 2003; 19(10): 875-81.
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, Issue.10
, pp. 875-881
-
-
Münk, C.1
Wei, G.2
Yang, O.O.3
-
220
-
-
84866906328
-
Inhibition of HIV-1 infection by human alpha-defensin-5, a natural antimicrobial peptide expressed in the genital and intestinal mucosae
-
Furci L, Tolazzi M, Sironi F, et al. Inhibition of HIV-1 infection by human alpha-defensin-5, a natural antimicrobial peptide expressed in the genital and intestinal mucosae. PLoS One 2012; 7(9): e45208.
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Furci, L.1
Tolazzi, M.2
Sironi, F.3
-
221
-
-
11144325117
-
Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro
-
Wu Z, Cocchi F, Gentles D, et al. Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro. FEBS Letters 2005; 579(1): 162-6.
-
(2005)
FEBS Letters
, vol.579
, Issue.1
, pp. 162-166
-
-
Wu, Z.1
Cocchi, F.2
Gentles, D.3
-
222
-
-
0037133343
-
Retrocyclin: A primate peptide that protects cells from infection by T-and M-tropic strains of HIV-1
-
Cole AM, Hong T, Boo LM, et al. Retrocyclin: a primate peptide that protects cells from infection by T-and M-tropic strains of HIV-1. Proc Natl Acad Sci USA 2002; 99(4): 1813-8.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.4
, pp. 1813-1818
-
-
Cole, A.M.1
Hong, T.2
Boo, L.M.3
-
223
-
-
9344221638
-
RC-101, a retrocyclin-1 analogue with enhanced activity against primary HIV type 1 isolates
-
Owen SM, Rudolph DL, Wang W, et al. RC-101, a retrocyclin-1 analogue with enhanced activity against primary HIV type 1 isolates. AIDS Res Hum Retroviruses 2004; 20(11): 1157-65.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, Issue.11
, pp. 1157-1165
-
-
Owen, S.M.1
Rudolph, D.L.2
Wang, W.3
-
224
-
-
65949105709
-
Reawakening retrocyclins: Ancestral human defensins active against HIV-1
-
Venkataraman N, Cole AL, Ruchala P, et al. Reawakening retrocyclins: ancestral human defensins active against HIV-1. PLoS Biol 2009; 7(4): e95.
-
(2009)
PLoS Biol
, vol.7
, Issue.4
-
-
Venkataraman, N.1
Cole, A.L.2
Ruchala, P.3
-
225
-
-
0028272132
-
Divergence in codon usage of Lactobacillus species
-
Pouwels PH, Leunissen JA. Leunissen, Divergence in codon usage of Lactobacillus species. Nucleic Acids Res 1994; 22(6): 929-36.
-
(1994)
Nucleic Acids Res
, vol.22
, Issue.6
, pp. 929-936
-
-
Pouwels, P.H.1
Leunissen, L.J.A.2
-
226
-
-
63049089307
-
A Chinese rhesus macaque (Macaca mulatta) model for vaginal Lactobacillus colonization and live microbicide development
-
Yu RR, Cheng AT, Lagenaur LA, et al. A Chinese rhesus macaque (Macaca mulatta) model for vaginal Lactobacillus colonization and live microbicide development. J Med Primatol 2009; 38(2): 125-36.
-
(2009)
J Med Primatol
, vol.38
, Issue.2
, pp. 125-136
-
-
Yu, R.R.1
Cheng, A.T.2
Lagenaur, L.A.3
-
227
-
-
0029822006
-
Effects of nonoxynol-9 on vaginal microflora and chlamydial infection in a monkey model
-
Patton DL, Kidder GG, Sweeney YC, et al. Effects of nonoxynol-9 on vaginal microflora and chlamydial infection in a monkey model. Sex Transm Dis 1996; 23(6): 461-4.
-
(1996)
Sex Transm Dis
, vol.23
, Issue.6
, pp. 461-464
-
-
Patton, D.L.1
Kidder, G.G.2
Sweeney, Y.C.3
-
228
-
-
84862908625
-
A comparison of lower genital tract glycogen and lactic acid levels in women and macaques: Implications for HIV and SIV susceptibility
-
Mirmonsef P, Gilbert D, Veazey RS, et al. A comparison of lower genital tract glycogen and lactic acid levels in women and macaques: implications for HIV and SIV susceptibility. AIDS Res Hum Retroviruses 2012; 28(1): 76-81.
-
(2012)
AIDS Res Hum Retroviruses
, vol.28
, Issue.1
, pp. 76-81
-
-
Mirmonsef, P.1
Gilbert, D.2
Veazey, R.S.3
-
229
-
-
0030789484
-
HIV-1 infection associated with abnormal vaginal flora morphology and bacterial vaginosis
-
Sewankambo N, Gray RH, Wawer MJ, et al. HIV-1 infection associated with abnormal vaginal flora morphology and bacterial vaginosis. Lancet 1997; 350(9077): 546-50.
-
(1997)
Lancet
, vol.350
, Issue.9077
, pp. 546-550
-
-
Sewankambo, N.1
Gray, R.H.2
Wawer, M.J.3
-
230
-
-
75749103762
-
Effect of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the ability of Candida albicans to infect cells and induce inflammation
-
Martinez RC, Seney SL, Summers KL, et al. Effect of Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the ability of Candida albicans to infect cells and induce inflammation. Microbiol Immunol 2009; 53(9): 487-95.
-
(2009)
Microbiol Immunol
, vol.53
, Issue.9
, pp. 487-495
-
-
Martinez, R.C.1
Seney, S.L.2
Summers, K.L.3
-
231
-
-
79960302320
-
Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide
-
Macho Fernandez E, Valenti V, Rockel C, et al. Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide. Gut 2011; 60(8): 1050-9.
-
(2011)
Gut
, vol.60
, Issue.8
, pp. 1050-1059
-
-
Macho Fernandez, E.1
Valenti, V.2
Rockel, C.3
-
232
-
-
84871983165
-
Fichorova, Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide
-
Yamamoto HS, Xu Q, Fichorova RN. Fichorova, Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide. BMC Microbiol 2013; 13: 4.
-
(2013)
BMC Microbiol
, vol.13
, pp. 4
-
-
Yamamoto, H.S.1
Xu, Q.2
Fichorova, R.N.3
-
233
-
-
41849125553
-
Considerations in the development of live biotherapeutic products for clinical use
-
Ross JJ, Boucher PE, Bhattacharyya SP, et al. Considerations in the development of live biotherapeutic products for clinical use. Curr Issues Mol Biol 2008; 10(1-2): 13-6.
-
(2008)
Curr Issues Mol Biol
, vol.10
, Issue.1-2
, pp. 13-16
-
-
Ross, J.J.1
Boucher, P.E.2
Bhattacharyya, S.P.3
-
234
-
-
84862792191
-
Testing of viscous anti-HIV microbicides using Lactobacillus
-
Moncla BJ, Pryke K, Rohan LC, Yang H. Testing of viscous anti-HIV microbicides using Lactobacillus. J Microbiol Methods 2012; 88(2): 292-6.
-
(2012)
J Microbiol Methods
, vol.88
, Issue.2
, pp. 292-296
-
-
Moncla, B.J.1
Pryke, K.2
Rohan, L.C.3
Yang, H.4
|