Evaluation of CD4-CD4i antibody architectures yields potent, broadly cross-reactive anti-human immunodeficiency virus reagents

Journal of Virology

Volumn 84, Issue 1, 2010, Pages 261-269

  West Jr , Anthony P ^a   Galimidi, Rachel P ^a   Foglesong, Christopher P ^a,b   Gnanapragasam, Priyanthi N P ^a   Klein, Joshua S ^a   Bjorkman, Pamela J ^a,b  

^a California Institute of Technology HHMI   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CD4 ANTIBODY; CD4 ANTIBODY MONOCLONAL ANTIBODY 2G12 FUSION PROTEIN; CD4 CD4 INDUCED 17B ANTIBODY; CD4 CD4 INDUCED 21C ANTIBODY; CD4 CD4 INDUCED E51 ANTIBODY; CD4 CD4 INDUCED M9 ANTIBODY; CROSS REACTING ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS RECEPTOR; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN; NEUTRALIZING ANTIBODY; REAGENT; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

ANTIBODY COMBINING SITE; ANTIBODY STRUCTURE; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DRUG HALF LIFE; DRUG POTENCY; GENE EXPRESSION; HEAVY CHAIN; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEOTIDE SEQUENCE; PASSIVE IMMUNIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS ENVELOPE; VIRUS NEUTRALIZATION; VIRUS REPLICATION; VIRUS STRAIN;

ANTI-HIV AGENTS; ANTIBODIES, BISPECIFIC; ANTIBODIES, VIRAL; ANTIGENS, CD4; BINDING SITES; CROSS REACTIONS; CROSS-LINKING REAGENTS; DRUG STABILITY; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 72849116535     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01528-09     Document Type: Article

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