Minimal variation in T-20 binding domain of different HIV-1 subtypes from antiretroviral-naive and -experienced patients

AIDS

Volumn 16, Issue 12, 2002, Pages 1684-1686

  Xu, Li ^a   Hué, Stéphane ^a   Taylor, Stephen ^a   Ratcliffe, Daina ^a   Workman, Judith A ^a   Jackson, Susan ^a   Cane, Patricia A ^a   Pillay, Deenan ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; COMPLEMENTARY DNA; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA;

ARTICLE; GENE MUTATION; GENETIC VARIABILITY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; NONHUMAN; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS RESISTANCE;

ANTI-HIV AGENTS; BASE SEQUENCE; DNA PRIMERS; HIV ENVELOPE PROTEIN GP41; HIV INFECTIONS; HUMANS; PEPTIDE FRAGMENTS;

EID: 0037119027     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200208160-00016     Document Type: Article

References (12)

1. Capture of an early fusion-active conformation of HIV-1 gp41
2. Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
3. Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides
4. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-28 is modulated by co-receptor specificity defined by the V3 loop of gp120
5. Resistance-associated mutations in the human immunodeficiency virus type 1 subtype C protease gene from treated and untreated patients in the United Kingdom
6. Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: Evidence of many minor drug resistance mutations in treatment-naive patients
7. Detection of drug resistance associated mutations in HIV primary infection within the UK
8. Human immunodeficiency virus reverse transcriptase and protease sequence database
9. Mutations in retroviral gene associated with drug resistance
10. Primary genotypic resistance of HIV-1 to the fusion inhibitor T-20 in long-term infected patients
11. Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor
12. Membrane-anchored peptide inhibits human immunodeficiency virus entry