메뉴 건너뛰기




Volumn 464, Issue 7286, 2010, Pages 217-223

Targeting early infection to prevent HIV-1 mucosal transmission

Author keywords

[No Author keywords available]

Indexed keywords

MICROBICIDE;

EID: 77949409948     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08757     Document Type: Review
Times cited : (498)

References (99)
  • 1
    • 0031958939 scopus 로고    scopus 로고
    • Cell-free and cell-associated viral stocks
    • cell-free and cell-associated viral stocks. AIDS Res. Hum. Retroviruses 14 (Suppl. 1), S119-S123 (1998).
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , Issue.SUPPL. 1
  • 2
    • 41949101138 scopus 로고    scopus 로고
    • Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239
    • Weiler, A. M. et al. Genital ulcers facilitate rapid viral entry and dissemination following intravaginal inoculation with cell-associated simian immunodeficiency virus SIVmac239. J. Virol. 82, 4154-4158 (2008).
    • (2008) J. Virol. , vol.82 , pp. 4154-4158
    • Weiler, A.M.1
  • 3
    • 33646122873 scopus 로고    scopus 로고
    • Rapid dissemination of a pathogenic simian/human immunodeficiency virus to systemic organs and active replication in lymphoid tissues following intrarectal infection
    • Miyake, A. et al. Rapid dissemination of a pathogenic simian/human immunodeficiency virus to systemic organs and active replication in lymphoid tissues following intrarectal infection. J. Gen. Virol. 87, 1311-1320 (2006).
    • (2006) J. Gen. Virol. , vol.87 , pp. 1311-1320
    • Miyake, A.1
  • 4
    • 0033588005 scopus 로고    scopus 로고
    • Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus
    • Stahl-Hennig, C. et al. Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus. Science 285, 1261-1265 (1999).
    • (1999) Science , vol.285 , pp. 1261-1265
    • Stahl-Hennig, C.1
  • 5
    • 11244294973 scopus 로고    scopus 로고
    • Rapid dissemination of SIV following oral inoculation
    • Milush, J. M. et al. Rapid dissemination of SIV following oral inoculation. AIDS 18, 1-10 (2004).
    • (2004) AIDS , vol.18 , pp. 1-10
    • Milush, J.M.1
  • 6
    • 0032540418 scopus 로고    scopus 로고
    • 1 T cell depletion and viral replication in SIV infection
    • 1 T cell depletion and viral replication in SIV infection. Science 280, 427-431 (1998).
    • (1998) Science , vol.280 , pp. 427-431
    • Veazey, R.S.1
  • 7
    • 17844374605 scopus 로고    scopus 로고
    • 1 T cells in multiple tissues during acute SIV infection
    • 1 T cells in multiple tissues during acute SIV infection. Nature 434, 1093-1097 (2005).
    • (2005) Nature , vol.434 , pp. 1093-1097
    • Mattapallil, J.1
  • 8
    • 17844376742 scopus 로고    scopus 로고
    • 1 T cells
    • 1 T cells. Nature 434, 1148-1152 (2005).
    • (2005) Nature , vol.434 , pp. 1148-1152
    • Li, Q.1
  • 9
    • 54249158122 scopus 로고    scopus 로고
    • UNAIDS
    • UNAIDS. 2008 Report on the global AIDS epidemic Æhttp://www.unaids. org/en/KnowledgeCentre/HIVData/GlobalReport/2008/2008-Global-report.aspæ (2008).
    • (2008) 2008 Report on the Global AIDS Epidemicæ
  • 10
    • 43749123908 scopus 로고    scopus 로고
    • 25 years of HIV
    • Fauci, A. S. 25 years of HIV. Nature 453, 289-290 (2008).
    • (2008) Nature , vol.453 , pp. 289-290
    • Fauci, A.S.1
  • 11
    • 49649129421 scopus 로고    scopus 로고
    • Treatment and prevention exchange vows at international conference
    • Cohen, J. Treatment and prevention exchange vows at international conference. Science 321, 902-903 (2008).
    • (2008) Science , vol.321 , pp. 902-903
    • Cohen, J.1
  • 12
    • 33847151707 scopus 로고    scopus 로고
    • Male circumcision for HIV prevention in young men in Kisumu Kenya: A randomised controlled trial
    • Bailey, R. C. et al. Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial. Lancet 369, 643-656 (2007).
    • (2007) Lancet , vol.369 , pp. 643-656
    • Bailey, R.C.1
  • 13
    • 28444460441 scopus 로고    scopus 로고
    • Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 Trial
    • Auvert, B. et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med. 2, e298 (2005).
    • (2005) PLoS Med. , vol.2
    • Auvert, B.1
  • 14
    • 33847104829 scopus 로고    scopus 로고
    • Male circumcision for HIV prevention in men in Rakai Uganda: A randomised trial
    • Gray, R. H. et al. Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial. Lancet 369, 657-666 (2007).
    • (2007) Lancet , vol.369 , pp. 657-666
    • Gray, R.H.1
  • 15
    • 73349094086 scopus 로고    scopus 로고
    • Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand
    • Rerks-Ngarm, S. et al. Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand. N. Engl. J. Med. 361, 2209-2220 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2209-2220
    • Rerks-Ngarm, S.1
  • 16
    • 60649084213 scopus 로고    scopus 로고
    • Safety and effectiveness of vaginal microbicides BufferGel and 0.5% PRO 2000/ 5 gel for the prevention of HIV infection in women: Results of the HPTN 035 trial
    • Karim, S. A. et al. Safety and effectiveness of vaginal microbicides BufferGel and 0.5% PRO 2000/5 gel for the prevention of HIV infection in women: Results of the HPTN 035 trial. Abstract 48LB (16th Conference on Retroviruses and Opportunistic Infections, 2009).
    • (2009) Abstract 48LB (16th Conference on Retroviruses and Opportunistic Infections
    • Karim, S.A.1
  • 17
    • 56649105122 scopus 로고    scopus 로고
    • Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): A double-blind, randomized, placebo-controlled, test-of-concept trial
    • Buchbinder, S. P. et al. Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomized, placebo-controlled, test-of-concept trial. Lancet 372, 1881-1893 (2008).
    • (2008) Lancet , vol.372 , pp. 1881-1893
    • Buchbinder, S.P.1
  • 18
    • 33847406114 scopus 로고    scopus 로고
    • Scientists rethink approach to HIV gels
    • Check, E. Scientists rethink approach to HIV gels. Nature 446, 12 (2007).
    • (2007) Nature , vol.446 , pp. 12
    • Check, E.1
  • 19
    • 48249134364 scopus 로고    scopus 로고
    • HIV vaccine research: The way forward
    • Fauci, A. et al. HIV vaccine research: the way forward. Science 321, 530-532 (2008).
    • (2008) Science , vol.321 , pp. 530-532
    • Fauci, A.1
  • 20
    • 20444399136 scopus 로고    scopus 로고
    • HIV/AIDS in women: An expanding epidemic
    • Quinn, T. C. & Overbaugh, J. HIV/AIDS in women: an expanding epidemic. Science 308, 1582-1583 (2005).
    • (2005) Science , vol.308 , pp. 1582-1583
    • Quinn, T.C.1    Overbaugh, J.2
  • 21
    • 0016600360 scopus 로고
    • The slow infection caused by visna virus
    • Haase, A. The slow infection caused by visna virus. Curr. Top. Microbiol. Immunol. 72, 101-156 (1975).
    • (1975) Curr. Top. Microbiol. Immunol. , vol.72 , pp. 101-156
    • Haase, A.1
  • 22
    • 0024464463 scopus 로고
    • Genital mucosal transmission of simian immunodeficiency virus: Animal model for heterosexual transmission of human immunodeficiency virus
    • Miller, C. J. et al. Genital mucosal transmission of simian immunodeficiency virus: animal model for heterosexual transmission of human immunodeficiency virus. J. Virol. 63, 4277-4284 (1989).
    • (1989) J. Virol. , vol.63 , pp. 4277-4284
    • Miller, C.J.1
  • 23
    • 0041828179 scopus 로고    scopus 로고
    • Dynamics of HIV viremia and seroconversion in plasma donors: Implications for diagnosis and staging of primary HIV infection
    • Fiebig, E. W. et al. Dynamics of HIV viremia and seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS 17, 1871-1879 (2003).
    • (2003) AIDS , vol.17 , pp. 1871-1879
    • Fiebig, E.W.1
  • 24
    • 21644455405 scopus 로고    scopus 로고
    • Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus
    • Miller, C. J. et al. Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus. J. Virol. 79, 9217-9227 (2005). Comprehensive tissue analysis of the pathogenesis of transmission and early infection in the nonhuman primate model of vaginal transmission of HIV-1.
    • (2005) J. Virol. , vol.79 , pp. 9217-9227
    • Miller, C.J.1
  • 25
    • 0034051289 scopus 로고    scopus 로고
    • Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells
    • Hu, J., Gardner, M. B. & Miller, C. J. Simian immunodeficiency virus rapidly penetrates the cervicovaginal mucosa after intravaginal inoculation and infects intraepithelial dendritic cells. J. Virol. 74, 6087-6095 (2000).
    • (2000) J. Virol. , vol.74 , pp. 6087-6095
    • Hu, J.1    Gardner, M.B.2    Miller, C.J.3
  • 26
    • 0032742547 scopus 로고    scopus 로고
    • 1 T cells
    • 1 T cells. Science 286, 1353-1357 (1999).
    • (1999) Science , vol.286 , pp. 1353-1357
    • Zhang, Z.-Q.1
  • 27
    • 0030729690 scopus 로고    scopus 로고
    • Simian immunodeficiency virus burden in tissues and cellular compartments during clinical latency and AIDS
    • Reinhart, T. et al. Simian immunodeficiency virus burden in tissues and cellular compartments during clinical latency and AIDS. J. Infect. Dis. 176, 1198-1208 (1997).
    • (1997) J. Infect. Dis. , vol.176 , pp. 1198-1208
    • Reinhart, T.1
  • 28
    • 0032971372 scopus 로고    scopus 로고
    • 1 T cell demographics and dynamics in lymphatic tissues
    • 1 T cell demographics and dynamics in lymphatic tissues. Annu. Rev. Immunol. 17, 625-656 (1999).
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 625-656
    • Haase, A.T.1
  • 29
    • 0037276929 scopus 로고    scopus 로고
    • Target cells in vaginal HIV transmission
    • Miller, C. M. & Shattock, R. J. Target cells in vaginal HIV transmission. Microbes Infect. 5, 59-67 (2003).
    • (2003) Microbes Infect. , vol.5 , pp. 59-67
    • Miller, C.M.1    Shattock, R.J.2
  • 30
    • 2142807626 scopus 로고    scopus 로고
    • Brief but efficient: Acute HIV infection and the sexual transmission of HIV
    • Christopher, D. P. et al. Brief but efficient: acute HIV infection and the sexual transmission of HIV. J. Infect. Dis. 189, 1785-1792 (2004).
    • (2004) J. Infect. Dis. , vol.189 , pp. 1785-1792
    • Christopher, D.P.1
  • 31
    • 66049157864 scopus 로고    scopus 로고
    • Low-dose rectal inoculation of rhesus macaques by SIV smE660 or SIVmac251 recapitulates human mucosal infection by HIV-1
    • Keele, B. F. et al. Low-dose rectal inoculation of rhesus macaques by SIV smE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. J. Exp. Med. 206, 1117-1134 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 1117-1134
    • Keele, B.F.1
  • 33
    • 0031023132 scopus 로고    scopus 로고
    • Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection
    • Clayton, F., Snow, G., Reka, S. & Kotler, D. P. Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection. Clin. Exp. Immunol. 107, 288-292 (1997).
    • (1997) Clin. Exp. Immunol. , vol.107 , pp. 288-292
    • Clayton, F.1    Snow, G.2    Reka, S.3    Kotler, D.P.4
  • 34
    • 4644289983 scopus 로고    scopus 로고
    • 1 T lymphocytes from effector sites in the gastrointestinal tract
    • 1 T lymphocytes from effector sites in the gastrointestinal tract. J. Exp. Med. 200, 761-770 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 761-770
    • Mehandru, S.1
  • 35
    • 4644342929 scopus 로고    scopus 로고
    • 1 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
    • 1 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200, 749-759 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 749-759
    • Brenchley, J.M.1
  • 36
    • 0142092389 scopus 로고    scopus 로고
    • 1 T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
    • 1 T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77, 11708-11717 (2003).
    • (2003) J. Virol. , vol.77 , pp. 11708-11717
    • Guadalupe, M.1
  • 37
    • 0021157562 scopus 로고
    • Enteropathy associated with the acquired immunodeficiency syndrome
    • Kotler, D. P., Gaetz, H. P., Lange, M., Klein, E. B. & Holt, P. R. Enteropathy associated with the acquired immunodeficiency syndrome. Ann. Intern. Med. 101, 421-428 (1984).
    • (1984) Ann. Intern. Med. , vol.101 , pp. 421-428
    • Kotler, D.P.1    Gaetz, H.P.2    Lange, M.3    Klein, E.B.4    Holt, P.R.5
  • 38
    • 0028100635 scopus 로고
    • Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction
    • Heise, C., Miller, C. J., Lackner, A. & Dandekar, S. Primary acute simian immunodeficiency virus infection of intestinal lymphoid tissue is associated with gastrointestinal dysfunction. J. Infect. Dis. 169, 1116-1120 (1994).
    • (1994) J. Infect. Dis. , vol.169 , pp. 1116-1120
    • Heise, C.1    Miller, C.J.2    Lackner, A.3    Dandekar, S.4
  • 39
    • 39349104176 scopus 로고    scopus 로고
    • Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection
    • Li, Q. et al. Simian immunodeficiency virus-induced intestinal cell apoptosis is the underlying mechanism of the regenerative enteropathy of early infection. J. Infect. Dis. 197, 420-429 (2008).
    • (2008) J. Infect. Dis. , vol.197 , pp. 420-429
    • Li, Q.1
  • 40
    • 33144476838 scopus 로고    scopus 로고
    • Premature induction of an immunosuppressive T regulatory response in acute SIV infection
    • Estes, J. D. et al. Premature induction of an immunosuppressive T regulatory response in acute SIV infection. J. Infect. Dis. 193, 703-712 (2006).
    • (2006) J. Infect. Dis. , vol.193 , pp. 703-712
    • Estes, J.D.1
  • 41
    • 21644488003 scopus 로고    scopus 로고
    • 1 T-lymphocyte response to major immunodominant epitopes after vaginal exposure to SIV: Too late and too little
    • 1 T-lymphocyte response to major immunodominant epitopes after vaginal exposure to SIV: too late and too little. J. Virol. 79, 9228-9235 (2005).
    • (2005) J. Virol. , vol.79 , pp. 9228-9235
    • Reynolds, M.R.1
  • 42
    • 33845532053 scopus 로고    scopus 로고
    • Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    • Brenchley, J. M. et al. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nature Med. 12, 1365-1371 (2006).
    • (2006) Nature Med. , vol.12 , pp. 1365-1371
    • Brenchley, J.M.1
  • 43
    • 33846785628 scopus 로고    scopus 로고
    • Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor b1-positive regulatory T cells and begins in early infection
    • Estes, J. D. et al. Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor b1-positive regulatory T cells and begins in early infection. J. Infect. Dis. 195, 551-561 (2007).
    • (2007) J. Infect. Dis. , vol.195 , pp. 551-561
    • Estes, J.D.1
  • 44
    • 50649117100 scopus 로고    scopus 로고
    • 1 T cells and limiting reconstitution of HIV-1 and SIV infections through damage to the secondary lymphoid organ niche
    • 1 T cells and limiting reconstitution of HIV-1 and SIV infections through damage to the secondary lymphoid organ niche. Semin. Immunol. 20, 181-186 (2008).
    • (2008) Semin. Immunol. , vol.20 , pp. 181-186
    • Estes, J.D.1    Haase, A.T.2    Schacker, T.W.3
  • 45
    • 0026551082 scopus 로고
    • Selective transmission of human deficiency virus type 1 variants from mothers to infants
    • Wolinsky, S. et al. Selective transmission of human deficiency virus type 1 variants from mothers to infants. Science 255, 1134-1137 (1992).
    • (1992) Science , vol.255 , pp. 1134-1137
    • Wolinsky, S.1
  • 46
    • 0029998895 scopus 로고    scopus 로고
    • Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission
    • Zhu, T. et al. Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: evidence for viral compartmentalization and selection during sexual transmission. J. Virol. 70, 3098-3107 (1996).
    • (1996) J. Virol. , vol.70 , pp. 3098-3107
    • Zhu, T.1
  • 47
    • 12144289425 scopus 로고    scopus 로고
    • Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission
    • Derdeyn, C. A. et al. Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science 303, 2019-2022 (2004). First description of the monophyletic nature of viruses transmitted heterosexually.
    • (2004) Science , vol.303 , pp. 2019-2022
    • Derdeyn, C.A.1
  • 48
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele, B. F. et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl Acad. Sci. USA 105, 7552-7557 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 7552-7557
    • Keele, B.F.1
  • 49
    • 66049139947 scopus 로고    scopus 로고
    • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
    • Salazar-Gonzalez, J. F. et al. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J. Exp. Med. 206, 1273-1289 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 1273-1289
    • Salazar-Gonzalez, J.F.1
  • 50
    • 0021355701 scopus 로고
    • Investigation of microtrauma after sexual intercourse
    • Norvell, M. K., Benrubi, G. I. & Thompson, R. J. Investigation of microtrauma after sexual intercourse. J. Reprod. Med. 269, 269-271 (1984).
    • (1984) J. Reprod. Med. , vol.269 , pp. 269-271
    • Norvell, M.K.1    Benrubi, G.I.2    Thompson, R.J.3
  • 51
    • 28144449069 scopus 로고    scopus 로고
    • Immunological microenvironments in the human vagina and cervix: Mediators of cellular immunity are concentrated in the cervical transformation zone
    • Pudney, J., Quayle, A. J. & Anderson, D. J. Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone. Biol. Reprod. 73, 1253-1263 (2005).
    • (2005) Biol. Reprod. , vol.73 , pp. 1253-1263
    • Pudney, J.1    Quayle, A.J.2    Anderson, D.J.3
  • 52
    • 56849097376 scopus 로고    scopus 로고
    • A tissue basis for colposcopic findings
    • O'Connor, D. M. A tissue basis for colposcopic findings. Obstet. Gynecol. Clin. North Am. 35, 565-582 (2008).
    • (2008) Obstet. Gynecol. Clin. North Am. , vol.35 , pp. 565-582
    • O'Connor, D.M.1
  • 53
    • 67349101763 scopus 로고    scopus 로고
    • Glycerol monolaurate prevents mucosal SIV transmission
    • Li, Q. et al. Glycerol monolaurate prevents mucosal SIV transmission. Nature 458, 1034-1038 (2009).
    • (2009) Nature , vol.458 , pp. 1034-1038
    • Li, Q.1
  • 54
    • 45249108765 scopus 로고    scopus 로고
    • Effect of acyclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: A randomized, double-blind, placebo-controlled trial
    • Celum, C. et al. Effect of acyclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomized, double-blind, placebo-controlled trial. Lancet 371, 2109-2119 (2008).
    • (2008) Lancet , vol.371 , pp. 2109-2119
    • Celum, C.1
  • 55
    • 42049102191 scopus 로고    scopus 로고
    • Effect of herpes simplex suppression on incidence of HIV among women in Tanzania
    • Watson-Jones, D. et al. Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. N. Engl. J. Med. 358, 1560-1571 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1560-1571
    • Watson-Jones, D.1
  • 56
    • 68349146396 scopus 로고    scopus 로고
    • Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition
    • Zhu, J. et al. Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nature Med. 15, 886-893 (2009).
    • (2009) Nature Med. , vol.15 , pp. 886-893
    • Zhu, J.1
  • 57
    • 33750291458 scopus 로고    scopus 로고
    • Nested case-control study of cervical mucosal lesions ectopy, and incident HIV infection among women in Cape Town
    • Myer, L., Wright, T. C. Jr, Denny, L. & Kuhn, L. Nested case-control study of cervical mucosal lesions ectopy, and incident HIV infection among women in Cape Town, South Africa. Sex. Transm. Dis. 33, 683-687 (2006).
    • (2006) South Africa. Sex. Transm. Dis. , vol.33 , pp. 683-687
    • Myer, L.1    Wright Jr., T.C.2    Denny, L.3    Kuhn, L.4
  • 58
    • 0026819035 scopus 로고
    • Mechanism of genital transmission of SIV: A hypothesis based on transmission studies and location of SIV in the genital tract of chronically infected female rhesus macaques
    • Miller, C. J., Alexander, N. J., Vogel, P., Anderson, J. & Marx, P. A. Mechanism of genital transmission of SIV: a hypothesis based on transmission studies and location of SIV in the genital tract of chronically infected female rhesus macaques. J. Med. Primatol. 21, 64-68 (1992).
    • (1992) J. Med. Primatol. , vol.21 , pp. 64-68
    • Miller, C.J.1    Alexander, N.J.2    Vogel, P.3    Anderson, J.4    Marx, P.A.5
  • 59
    • 0026486269 scopus 로고
    • HIV infection in a patient with Meyer-Rokitansky-Kuster-Hauser syndrome
    • Kell, P. D., Barton, S. E., Edmonds, D. K. & Boag, F. C. HIV infection in a patient with Meyer-Rokitansky-Kuster-Hauser syndrome. J. R. Soc. Med. 85, 706-707 (1992).
    • (1992) J. R. Soc. Med. , vol.85 , pp. 706-707
    • Kell, P.D.1    Barton, S.E.2    Edmonds, D.K.3    Boag, F.C.4
  • 60
    • 34447527138 scopus 로고    scopus 로고
    • Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: A randomisedcontrolled trial
    • Padian, N. S. et al. Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomisedcontrolled trial. Lancet 370, 251-261 (2007).
    • (2007) Lancet , vol.370 , pp. 251-261
    • Padian, N.S.1
  • 61
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    • Berger, E. A., Murphy, P. M. & Farber, J. M. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17, 657-700 (1999).
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 62
    • 39449098115 scopus 로고    scopus 로고
    • HIV-1 envelope binds to and signals through integrin a4b7, the gut mucosal homing receptor for peripheral T cells
    • Arthos, J. et al. HIV-1 envelope binds to and signals through integrin a4b7, the gut mucosal homing receptor for peripheral T cells. Nature Immunol.9, 301-309 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 301-309
    • Arthos, J.1
  • 63
    • 69249153068 scopus 로고    scopus 로고
    • H-17 cells and are preferentially infected during acute SIV infection
    • H-17 cells and are preferentially infected during acute SIV infection. Mucosal Immunol. 2, 439-449 (2009).
    • (2009) Mucosal Immunol. , vol.2 , pp. 439-449
    • Kader, M.1
  • 64
    • 1842782773 scopus 로고    scopus 로고
    • 1 T cells in transmission and acute simian immunodeficiency virus infection
    • 1 T cells in transmission and acute simian immunodeficiency virus infection. Proc. Natl Acad. Sci. USA 101, 5640-5645 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 5640-5645
    • Zhang, Z.-Q.1
  • 65
    • 0035865791 scopus 로고    scopus 로고
    • Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection
    • Schacker, T. S. et al. Productive infection of T cells in lymphoid tissues during primary and early human immunodeficiency virus infection. J. Infect. Dis. 183, 555-562 (2001).
    • (2001) J. Infect. Dis. , vol.183 , pp. 555-562
    • Schacker, T.S.1
  • 66
    • 0034899548 scopus 로고    scopus 로고
    • The number and distribution of immune cells in the cervicovaginal mucosa remain constant throughout the menstrual cycle of rhesus macaques
    • Ma, Z., Lü, F. X., Torten, M. & Miller, C. J. The number and distribution of immune cells in the cervicovaginal mucosa remain constant throughout the menstrual cycle of rhesus macaques. Clin. Immunol. 100, 240-249 (2001).
    • (2001) Clin. Immunol. , vol.100 , pp. 240-249
    • Ma, Z.1    Lü, F.X.2    Torten, M.3    Miller, C.J.4
  • 67
    • 0021845494 scopus 로고
    • Langerhans' cells and lymphocyte subsets in the female genital tract
    • Edwards, J. N. T. & Morris, H. B. Langerhans' cells and lymphocyte subsets in the female genital tract. Br. J. Obstet. Gynaecol. 92, 974-982 (1985).
    • (1985) Br. J. Obstet. Gynaecol. , vol.92 , pp. 974-982
    • Edwards, J.N.T.1    Morris, H.B.2
  • 68
    • 23344453110 scopus 로고    scopus 로고
    • Innate and adaptive immunity in female genital tract: Cellular responses and interactions
    • Wira, C. R., Fahey, J. V., Sentman, C. L., Pioli, P. A. & Shen, L. Innate and adaptive immunity in female genital tract: cellular responses and interactions. Immunol. Rev. 206, 306-335 (2005).
    • (2005) Immunol. Rev. , vol.206 , pp. 306-335
    • Wira, C.R.1    Fahey, J.V.2    Sentman, C.L.3    Pioli, P.A.4    Shen, L.5
  • 69
    • 14644404417 scopus 로고    scopus 로고
    • Epithelial cells in the female reproductive tract: A central role as sentinels of immune protection
    • Wira, C. R., Grant-Tschudy, K. S. & Crane-Godreau, M. A. Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection. Am. J. Reprod. Immunol. 53, 65-76 (2005).
    • (2005) Am. J. Reprod. Immunol. , vol.53 , pp. 65-76
    • Wira, C.R.1    Grant-Tschudy, K.S.2    Crane-Godreau, M.A.3
  • 70
    • 45449085276 scopus 로고    scopus 로고
    • Estradiol selectively regulates innate immune function by polarized human uterine epithelial cells in culture
    • Fahey, J. V. et al. Estradiol selectively regulates innate immune function by polarized human uterine epithelial cells in culture. Mucosal Immunol. 1, 317-325 (2008).
    • (2008) Mucosal Immunol. , vol.1 , pp. 317-325
    • Fahey, J.V.1
  • 71
    • 0034605067 scopus 로고    scopus 로고
    • Macrophage inflammatory protein 3a is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors
    • Dieu-nosjean, M. et al. Macrophage inflammatory protein 3a is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J. Exp. Med. 192, 705-717 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 705-717
    • Dieu-Nosjean, M.1
  • 72
    • 22144464047 scopus 로고    scopus 로고
    • Characterization of CCL20 secretion by human epithelial vaginal cells: Involvement in Langerhans cell precursor attraction
    • Cremel, M. et al. Characterization of CCL20 secretion by human epithelial vaginal cells: involvement in Langerhans cell precursor attraction. J. Leukoc. Biol. 78, 158-166 (2005).
    • (2005) J. Leukoc. Biol. , vol.78 , pp. 158-166
    • Cremel, M.1
  • 73
    • 25144479948 scopus 로고    scopus 로고
    • Temporal and anatomic relationship between virus replication and cytokine gene expression after vaginal simian immunodeficiency virus infection
    • Abel, K., Rocke, D. M., Chohan, B., Fritts, L. & Miller, C. J. Temporal and anatomic relationship between virus replication and cytokine gene expression after vaginal simian immunodeficiency virus infection. J. Virol. 79, 12164-12172 (2005).
    • (2005) J. Virol. , vol.79 , pp. 12164-12172
    • Abel, K.1    Rocke, D.M.2    Chohan, B.3    Fritts, L.4    Miller, C.J.5
  • 74
    • 0035857959 scopus 로고    scopus 로고
    • Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda
    • Gray, R. H. et al. Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet 357, 1149-1153 (2001).
    • (2001) Lancet , vol.357 , pp. 1149-1153
    • Gray, R.H.1
  • 75
    • 20244368227 scopus 로고    scopus 로고
    • Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda
    • Wawer, M. J. et al. Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J. Infect. Dis. 191, 1403-1409 (2005).
    • (2005) J. Infect. Dis. , vol.191 , pp. 1403-1409
    • Wawer, M.J.1
  • 76
    • 70349753255 scopus 로고    scopus 로고
    • Partial inhibition of human immunodeficiency virus replication by type i interferons: Impact of cell-to-cell viral transfer
    • Vendrame, D., Sourisseau, M., Perrin, V., Schwartz, O. & Mamano, F. Partial inhibition of human immunodeficiency virus replication by type I interferons: Impact of cell-to-cell viral transfer. J. Virol. 83, 10527-10537 (2009).
    • (2009) J. Virol. , vol.83 , pp. 10527-10537
    • Vendrame, D.1    Sourisseau, M.2    Perrin, V.3    Schwartz, O.4    Mamano, F.5
  • 77
    • 66149137185 scopus 로고    scopus 로고
    • Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses
    • Rudnicka, D. et al. Simultaneous cell-to-cell transmission of human immunodeficiency virus to multiple targets through polysynapses. J. Virol. 83, 6234-6246 (2009).
    • (2009) J. Virol. , vol.83 , pp. 6234-6246
    • Rudnicka, D.1
  • 78
    • 27644446403 scopus 로고    scopus 로고
    • The toll-like receptor 7 (TLR7) agonist, imiquimod and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques
    • Wang, Y. et al. The toll-like receptor 7 (TLR7) agonist, imiquimod and the TLR9 agonist, CpG ODN, induce antiviral cytokines and chemokines but do not prevent vaginal transmission of simian immunodeficiency virus when applied intravaginally to rhesus macaques. J. Virol. 79, 14355-14370 (2005).
    • (2005) J. Virol. , vol.79 , pp. 14355-14370
    • Wang, Y.1
  • 79
    • 1842486661 scopus 로고    scopus 로고
    • The role of sexually transmitted diseases in HIV transmission
    • Glavin, S. R. & Cohen, M. S. The role of sexually transmitted diseases in HIV transmission. Nature Rev. Microbiol. 2, 33-42 (2004).
    • (2004) Nature Rev. Microbiol. , vol.2 , pp. 33-42
    • Glavin, S.R.1    Cohen, M.S.2
  • 80
    • 38149074165 scopus 로고    scopus 로고
    • The genital tract immune milieu: An important determinant of HIV susceptibility and secondary transmission
    • Kaul, R. et al. The genital tract immune milieu: an important determinant of HIV susceptibility and secondary transmission. J. Reprod. Immunol. 77, 32-40 (2008).
    • (2008) J. Reprod. Immunol. , vol.77 , pp. 32-40
    • Kaul, R.1
  • 81
    • 59249096215 scopus 로고    scopus 로고
    • Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1
    • Haaland, R. E. et al. Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1. PLoS Pathog. 5, 1-13 (2009).
    • (2009) PLoS Pathog. , vol.5 , pp. 1-13
    • Haaland, R.E.1
  • 82
    • 27944465772 scopus 로고    scopus 로고
    • Seminal plasma and male factor signalling in the female reproductive tract
    • Robertson, S. A. Seminal plasma and male factor signalling in the female reproductive tract. Cell Tissue Res. 322, 43-52 (2005).
    • (2005) Cell Tissue Res. , vol.322 , pp. 43-52
    • Robertson, S.A.1
  • 84
    • 33645823400 scopus 로고    scopus 로고
    • Seminal plasma promotes the attraction of Langerhans cells via the secretion of CCL20 by vaginal epithelial cells: Involvement in the sexual transmission of HIV
    • Berlier, W. et al. Seminal plasma promotes the attraction of Langerhans cells via the secretion of CCL20 by vaginal epithelial cells: involvement in the sexual transmission of HIV. Hum. Reprod. 21, 1135-1142 (2006).
    • (2006) Hum. Reprod. , vol.21 , pp. 1135-1142
    • Berlier, W.1
  • 85
    • 36849093472 scopus 로고    scopus 로고
    • Semen-derived amyloid fibrils drastically enhance HIV infection
    • Münch, J. et al. Semen-derived amyloid fibrils drastically enhance HIV infection. Cell 131, 1059-1071 (2007).
    • (2007) Cell , vol.131 , pp. 1059-1071
    • Münch, J.1
  • 86
    • 63449103666 scopus 로고    scopus 로고
    • Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection
    • Li, Q. et al. Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection. Science 323, 1726-1729 (2009).
    • (2009) Science , vol.323 , pp. 1726-1729
    • Li, Q.1
  • 87
    • 33645748846 scopus 로고    scopus 로고
    • 1 CTLs in delay of AIDS viral dissemination from mucosa
    • 1 CTLs in delay of AIDS viral dissemination from mucosa. Blood 107, 3258-3264 (2006).
    • (2006) Blood , vol.107 , pp. 3258-3264
    • Belyakov, I.M.1
  • 88
    • 42149098404 scopus 로고    scopus 로고
    • Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys
    • Genescà, M., Skinner, P. J., Bost, K. M., Lu, D. & Wang, Y. Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys. Mucosal Immunol. 1, 219-228 (2008).
    • (2008) Mucosal Immunol. , vol.1 , pp. 219-228
    • Genescà, M.1    Skinner, P.J.2    Bost, K.M.3    Lu, D.4    Wang, Y.5
  • 89
    • 61949216736 scopus 로고    scopus 로고
    • Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge
    • Hansen, S. G. et al. Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge. Nature Med. 15, 293-299 (2009).
    • (2009) Nature Med. , vol.15 , pp. 293-299
    • Hansen, S.G.1
  • 90
    • 17344384248 scopus 로고    scopus 로고
    • Containment of simian immunodeficiency virus infection: Cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment
    • Lifson, J. D. et al. Containment of simian immunodeficiency virus infection: Cellular immune responses and protection from rechallenge following transient postinoculation antiretroviral treatment. J. Virol. 74, 2584-2593 (2000).
    • (2000) J. Virol. , vol.74 , pp. 2584-2593
    • Lifson, J.D.1
  • 91
    • 27744571425 scopus 로고    scopus 로고
    • Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion
    • Veazey, R. S. et al. Protection of macaques from vaginal SHIV challenge by vaginally delivered inhibitors of virus-cell fusion. Nature 438, 99-102 (2005).
    • (2005) Nature , vol.438 , pp. 99-102
    • Veazey, R.S.1
  • 92
    • 5644247983 scopus 로고    scopus 로고
    • Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
    • Lederman, M. M. et al. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 306, 485-487 (2004).
    • (2004) Science , vol.306 , pp. 485-487
    • Lederman, M.M.1
  • 93
    • 50949097030 scopus 로고    scopus 로고
    • Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel
    • Cranage, M. et al. Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel. PLoS Med. 5, 1238-1250 (2008).
    • (2008) PLoS Med. , vol.5 , pp. 1238-1250
    • Cranage, M.1
  • 94
    • 0038365560 scopus 로고    scopus 로고
    • Persistence of extraordinarily low levels of genetically homogeneous human immunodeficiency virus type 1 in exposed seronegative individuals
    • Zhu, T. et al. Persistence of extraordinarily low levels of genetically homogeneous human immunodeficiency virus type 1 in exposed seronegative individuals. J. Virol. 77, 6108-6116 (2003).
    • (2003) J. Virol. , vol.77 , pp. 6108-6116
    • Zhu, T.1
  • 95
    • 0031744018 scopus 로고    scopus 로고
    • 1-T-cell proliferative responses in rhesus macaques that were transiently viremic after intravaginal inoculation of SIV
    • 1-T-cell proliferative responses in rhesus macaques that were transiently viremic after intravaginal inoculation of SIV. J. Virol. 72, 10029-10035 (1998).
    • (1998) J. Virol. , vol.72 , pp. 10029-10035
    • McChesney, M.B.1
  • 96
    • 10044227530 scopus 로고    scopus 로고
    • A period of transient viremia and occult infection precedes persistent viremia and antiviral immune responses during multiple low-dose intravaginal simian immunodeficiency virus inoculations
    • Ma, Z.-M., Abel, K., Rourke, T., Wang, Y. & Miller, C. J. A period of transient viremia and occult infection precedes persistent viremia and antiviral immune responses during multiple low-dose intravaginal simian immunodeficiency virus inoculations. J. Virol. 78, 14048-14052 (2004).
    • (2004) J. Virol. , vol.78 , pp. 14048-14052
    • Ma, Z.-M.1    Abel, K.2    Rourke, T.3    Wang, Y.4    Miller, C.J.5
  • 97
    • 0029843061 scopus 로고    scopus 로고
    • Intrarectal transmission of simian immunodeficiency virus in rhesus macaques: Selective amplification and host responses to transient or persistent viremia
    • Trivedi, P. et al. Intrarectal transmission of simian immunodeficiency virus in rhesus macaques: selective amplification and host responses to transient or persistent viremia. J. Virol. 70, 6876-6883 (1996).
    • (1996) J. Virol. , vol.70 , pp. 6876-6883
    • Trivedi, P.1
  • 98
    • 68149168652 scopus 로고    scopus 로고
    • Microarray analysis of lymphatic tissue reveals stage-specific, gene expression signatures in HIV-1 infection
    • Li, Q. et al. Microarray analysis of lymphatic tissue reveals stage-specific, gene expression signatures in HIV-1 infection. J. Immunol. 183, 1975-1982 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 1975-1982
    • Li, Q.1
  • 99
    • 77949384495 scopus 로고    scopus 로고
    • Immunology and the elusive AIDS vaccine
    • in the press
    • Virgin, H. W. & Walker, B. D. Immunology and the elusive AIDS vaccine. Nature. (in the press).
    • Nature
    • Virgin, H.W.1    Walker, B.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.