Novel miniproteins engineered by the transfer of active sites to small natural scaffolds

Biopolymers

Volumn 47, Issue 1, 1998, Pages 93-100

  Vita, Claudio ^a   Vizzavona, Jean ^a   Sophie, Drakopoulou ^a   Bernard, Zinn Justin ^a   Menez, Gilquin André ^a  

^a CEA SACLAY   (France)

Author keywords

Leads for drug design; Miniproteins; Protein mimics; Scorpion toxin; Structural motif; Structural templates; Timltidisiilfide containing proteins

Indexed keywords

AMINO ACIDS; CHEMICAL BONDS; CONFORMATIONS; MOLECULAR STRUCTURE; SULFUR COMPOUNDS;

MINIPROTEINS;

PROTEINS;

CD4 ANTIGEN; CHARYBDOTOXIN; CHOLINERGIC RECEPTOR; DISULFIDE; GLYCOPROTEIN GP 120; HUMAN SERUM ALBUMIN; NEUROMUSCULAR BLOCKING AGENT; NEUROTOXIN; SCORPION VENOM; SNAKE VENOM;

BIOENGINEERING; HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN STRUCTURE; REVIEW; STRUCTURE ACTIVITY RELATION; VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD4; BINDING SITES; BIOPOLYMERS; CURARE; DRUG DESIGN; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; SCORPIONES; SERPENTES;

EID: 0031904693     PISSN: 00063525     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0282(1998)47:1<93::aid-bip10>3.0.co;2-h     Document Type: Article

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