The potent anti-HIV protein cyanovirin-N contains two novel carbohydrate binding sites that selectively bind to Man8 D1D3 and Man9 with nanomolar affinity: Implications for binding to the HIV envelope protein gp120

Journal of the American Chemical Society

Volumn 123, Issue 17, 2001, Pages 3892-3902

  Bewley, C A ^a   Otero Quintero, S ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL FUSION;

CALORIMETRY; CARBOHYDRATES; CELL CULTURE; IMMUNOLOGY; ISOMERS; STOICHIOMETRY; TITRATION; VIRUSES;

PROTEINS;

ANTIVIRUS AGENT; CYANOVIRIN N; GLYCOPROTEIN GP 120; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALORIMETRY; CARBOHYDRATE ANALYSIS; CELL FUSION; CROSS LINKING; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOMERISM; NONHUMAN; NONLINEAR SYSTEM; PROTEIN PROTEIN INTERACTION; TITRIMETRY;

ANTI-HIV AGENTS; BACTERIAL PROTEINS; BINDING SITES; CARBOHYDRATE SEQUENCE; CARRIER PROTEINS; CELL FUSION; HIV ENVELOPE PROTEIN GP120; MANNOSE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OLIGOSACCHARIDES; PROTEIN BINDING; VACCINIA VIRUS;

EID: 0034799906     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja004040e     Document Type: Article

References (50)