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Volumn 35, Issue 3, 2014, Pages 114-122

Dendritic cells in progression and pathology of HIV infection

Author keywords

Dendritic; HIV; Immune activation; Infection; Pathogenesis

Indexed keywords

DENDRITIC; HIV; IMMUNE ACTIVATION; INFECTION; PATHOGENESIS;

EID: 84894435407     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2013.10.003     Document Type: Review
Times cited : (81)

References (125)
  • 1
    • 0031985820 scopus 로고    scopus 로고
    • Host and viral factors influencing heterosexual HIV transmission
    • Miller C.J. Host and viral factors influencing heterosexual HIV transmission. Rev. Reprod. 1998, 3:42-51.
    • (1998) Rev. Reprod. , vol.3 , pp. 42-51
    • Miller, C.J.1
  • 2
    • 0031712324 scopus 로고    scopus 로고
    • Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation
    • Sallusto F., et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur. J. Immunol. 1998, 28:2760-2769.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2760-2769
    • Sallusto, F.1
  • 3
    • 0036793294 scopus 로고    scopus 로고
    • Diversity of receptors binding HIV on dendritic cell subsets
    • Turville S.G., et al. Diversity of receptors binding HIV on dendritic cell subsets. Nat. Immunol. 2002, 3:975-983.
    • (2002) Nat. Immunol. , vol.3 , pp. 975-983
    • Turville, S.G.1
  • 4
    • 51649113484 scopus 로고    scopus 로고
    • The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways
    • Lambert A.A., et al. The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways. Blood 2008, 112:1299-1307.
    • (2008) Blood , vol.112 , pp. 1299-1307
    • Lambert, A.A.1
  • 5
    • 37649009793 scopus 로고    scopus 로고
    • Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1
    • de Witte L., et al. Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:19464-19469.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 19464-19469
    • de Witte, L.1
  • 6
    • 27644513772 scopus 로고    scopus 로고
    • Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions
    • Beignon A.S., et al. Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions. J. Clin. Invest. 2005, 115:3265-3275.
    • (2005) J. Clin. Invest. , vol.115 , pp. 3265-3275
    • Beignon, A.S.1
  • 7
    • 27744532338 scopus 로고    scopus 로고
    • HIV-infected cells are major inducers of plasmacytoid dendritic cell interferon production, maturation, and migration
    • Schmidt B., et al. HIV-infected cells are major inducers of plasmacytoid dendritic cell interferon production, maturation, and migration. Virology 2005, 343:256-266.
    • (2005) Virology , vol.343 , pp. 256-266
    • Schmidt, B.1
  • 8
    • 84879654670 scopus 로고    scopus 로고
    • Human plasmacytoid dendritic cells efficiently capture hiv-1 envelope glycoproteins via CD4 for antigen presentation
    • Sandgren K.J., et al. Human plasmacytoid dendritic cells efficiently capture hiv-1 envelope glycoproteins via CD4 for antigen presentation. J. Immunol. 2013, 191:60-69.
    • (2013) J. Immunol. , vol.191 , pp. 60-69
    • Sandgren, K.J.1
  • 9
    • 63849314148 scopus 로고    scopus 로고
    • Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway
    • Izquierdo-Useros N., et al. Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway. Blood 2009, 113:2732-2741.
    • (2009) Blood , vol.113 , pp. 2732-2741
    • Izquierdo-Useros, N.1
  • 10
    • 64049115907 scopus 로고    scopus 로고
    • Glycosphingolipid composition of human immunodeficiency virus type 1 (HIV-1) particles is a crucial determinant for dendritic cell-mediated HIV-1 trans-infection
    • Hatch S.C., et al. Glycosphingolipid composition of human immunodeficiency virus type 1 (HIV-1) particles is a crucial determinant for dendritic cell-mediated HIV-1 trans-infection. J. Virol. 2009, 83:3496-3506.
    • (2009) J. Virol. , vol.83 , pp. 3496-3506
    • Hatch, S.C.1
  • 11
    • 0242492512 scopus 로고    scopus 로고
    • Binding of human immunodeficiency virus type 1 to immature dendritic cells can occur independently of DC-SIGN and mannose binding C-type lectin receptors via a cholesterol-dependent pathway
    • Gummuluru S., et al. Binding of human immunodeficiency virus type 1 to immature dendritic cells can occur independently of DC-SIGN and mannose binding C-type lectin receptors via a cholesterol-dependent pathway. J. Virol. 2003, 77:12865-12874.
    • (2003) J. Virol. , vol.77 , pp. 12865-12874
    • Gummuluru, S.1
  • 12
    • 77957690135 scopus 로고    scopus 로고
    • PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection
    • Hanley T.M., et al. PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection. PLoS Pathog. 2010, 6:e1000981.
    • (2010) PLoS Pathog. , vol.6
    • Hanley, T.M.1
  • 13
    • 34447270265 scopus 로고    scopus 로고
    • Maturation of blood-derived dendritic cells enhances human immunodeficiency virus type 1 capture and transmission
    • Izquierdo-Useros N., et al. Maturation of blood-derived dendritic cells enhances human immunodeficiency virus type 1 capture and transmission. J. Virol. 2007, 81:7559-7570.
    • (2007) J. Virol. , vol.81 , pp. 7559-7570
    • Izquierdo-Useros, N.1
  • 14
    • 79952217825 scopus 로고    scopus 로고
    • Innate sensing of HIV-infected cells
    • Lepelley A., et al. Innate sensing of HIV-infected cells. PLoS Pathog. 2011, 7:e1001284.
    • (2011) PLoS Pathog. , vol.7
    • Lepelley, A.1
  • 15
    • 0034598905 scopus 로고    scopus 로고
    • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
    • Geijtenbeek T.B., et al. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 2000, 100:587-597.
    • (2000) Cell , vol.100 , pp. 587-597
    • Geijtenbeek, T.B.1
  • 16
    • 33847755116 scopus 로고    scopus 로고
    • Langerin is a natural barrier to HIV-1 transmission by Langerhans cells
    • de Witte L., et al. Langerin is a natural barrier to HIV-1 transmission by Langerhans cells. Nat. Med. 2007, 13:367-371.
    • (2007) Nat. Med. , vol.13 , pp. 367-371
    • de Witte, L.1
  • 17
    • 79952234401 scopus 로고    scopus 로고
    • Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-alpha-producing and partially matured phenotype
    • O'Brien M., et al. Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-alpha-producing and partially matured phenotype. J. Clin. Invest. 2011, 121:1088-1101.
    • (2011) J. Clin. Invest. , vol.121 , pp. 1088-1101
    • O'Brien, M.1
  • 18
    • 67349101763 scopus 로고    scopus 로고
    • Glycerol monolaurate prevents mucosal SIV transmission
    • Li Q., et al. Glycerol monolaurate prevents mucosal SIV transmission. Nature 2009, 458:1034-1038.
    • (2009) Nature , vol.458 , pp. 1034-1038
    • Li, Q.1
  • 19
    • 70349744046 scopus 로고    scopus 로고
    • TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells
    • Fontenot D., et al. TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:16776-16781.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 16776-16781
    • Fontenot, D.1
  • 20
    • 1842782773 scopus 로고    scopus 로고
    • Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection
    • Zhang Z.Q., et al. Roles of substrate availability and infection of resting and activated CD4+ T cells in transmission and acute simian immunodeficiency virus infection. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:5640-5645.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 5640-5645
    • Zhang, Z.Q.1
  • 21
    • 21644455405 scopus 로고    scopus 로고
    • Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus
    • Miller C.J., et al. Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus. J. Virol. 2005, 79:9217-9227.
    • (2005) J. Virol. , vol.79 , pp. 9217-9227
    • Miller, C.J.1
  • 22
    • 0026625135 scopus 로고
    • Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells
    • Cameron P.U., et al. Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells. Science 1992, 257:383-387.
    • (1992) Science , vol.257 , pp. 383-387
    • Cameron, P.U.1
  • 23
    • 0028131579 scopus 로고
    • Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1
    • Pope M., et al. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 1994, 78:389-398.
    • (1994) Cell , vol.78 , pp. 389-398
    • Pope, M.1
  • 24
    • 22344452391 scopus 로고    scopus 로고
    • Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells
    • Lore K., et al. Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells. J. Exp. Med. 2005, 201:2023-2033.
    • (2005) J. Exp. Med. , vol.201 , pp. 2023-2033
    • Lore, K.1
  • 25
    • 0030026189 scopus 로고    scopus 로고
    • The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation
    • Weissman D., et al. The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation. J. Exp. Med. 1996, 183:687-692.
    • (1996) J. Exp. Med. , vol.183 , pp. 687-692
    • Weissman, D.1
  • 26
    • 0037007670 scopus 로고    scopus 로고
    • HIV preferentially infects HIV-specific CD4+ T cells
    • Douek D.C., et al. HIV preferentially infects HIV-specific CD4+ T cells. Nature 2002, 417:95-98.
    • (2002) Nature , vol.417 , pp. 95-98
    • Douek, D.C.1
  • 27
    • 0038025223 scopus 로고    scopus 로고
    • Recruitment of HIV and its receptors to dendritic cell-T cell junctions
    • McDonald D., et al. Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science 2003, 300:1295-1297.
    • (2003) Science , vol.300 , pp. 1295-1297
    • McDonald, D.1
  • 28
    • 33847197497 scopus 로고    scopus 로고
    • Dendritic cell-mediated trans-enhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN
    • Boggiano C., et al. Dendritic cell-mediated trans-enhancement of human immunodeficiency virus type 1 infectivity is independent of DC-SIGN. J. Virol. 2007, 81:2519-2523.
    • (2007) J. Virol. , vol.81 , pp. 2519-2523
    • Boggiano, C.1
  • 29
    • 21644483118 scopus 로고    scopus 로고
    • Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells
    • Smed-Sorensen A., et al. Differential susceptibility to human immunodeficiency virus type 1 infection of myeloid and plasmacytoid dendritic cells. J. Virol. 2005, 79:8861-8869.
    • (2005) J. Virol. , vol.79 , pp. 8861-8869
    • Smed-Sorensen, A.1
  • 30
    • 33845906383 scopus 로고    scopus 로고
    • APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
    • Pion M., et al. APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection. J. Exp. Med. 2006, 203:2887-2893.
    • (2006) J. Exp. Med. , vol.203 , pp. 2887-2893
    • Pion, M.1
  • 31
    • 0344413641 scopus 로고    scopus 로고
    • The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
    • Sheehy A.M., et al. The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. Nat. Med. 2003, 9:1404-1407.
    • (2003) Nat. Med. , vol.9 , pp. 1404-1407
    • Sheehy, A.M.1
  • 32
    • 84859496523 scopus 로고    scopus 로고
    • TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling
    • Grutter M.G., Luban J. TRIM5 structure, HIV-1 capsid recognition, and innate immune signaling. Curr. Opin. Virol. 2012, 2:142-150.
    • (2012) Curr. Opin. Virol. , vol.2 , pp. 142-150
    • Grutter, M.G.1    Luban, J.2
  • 33
    • 79960396329 scopus 로고    scopus 로고
    • Modulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms
    • Battivelli E., et al. Modulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms. J. Virol. 2011, 85:7828-7835.
    • (2011) J. Virol. , vol.85 , pp. 7828-7835
    • Battivelli, E.1
  • 34
    • 79955114733 scopus 로고    scopus 로고
    • Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef
    • Coleman C.M., et al. Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef. Retrovirology 2011, 8:26.
    • (2011) Retrovirology , vol.8 , pp. 26
    • Coleman, C.M.1
  • 35
    • 79959858243 scopus 로고    scopus 로고
    • Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
    • Hrecka K., et al. Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein. Nature 2011, 474:658-661.
    • (2011) Nature , vol.474 , pp. 658-661
    • Hrecka, K.1
  • 36
    • 79959843617 scopus 로고    scopus 로고
    • SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
    • Laguette N., et al. SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx. Nature 2011, 474:654-657.
    • (2011) Nature , vol.474 , pp. 654-657
    • Laguette, N.1
  • 37
    • 83555164881 scopus 로고    scopus 로고
    • HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
    • Goldstone D.C., et al. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase. Nature 2011, 480:379-382.
    • (2011) Nature , vol.480 , pp. 379-382
    • Goldstone, D.C.1
  • 38
    • 84862777555 scopus 로고    scopus 로고
    • SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
    • Lahouassa H., et al. SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates. Nat. Immunol. 2012, 13:223-228.
    • (2012) Nat. Immunol. , vol.13 , pp. 223-228
    • Lahouassa, H.1
  • 39
    • 84876369203 scopus 로고    scopus 로고
    • The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation
    • White T.E., et al. The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation. Cell Host Microbe 2013, 13:441-451.
    • (2013) Cell Host Microbe , vol.13 , pp. 441-451
    • White, T.E.1
  • 40
    • 84893463287 scopus 로고    scopus 로고
    • HIV-1 infection of plasmacytoid and myeloid dendritic cells is restricted by high levels of SAMHD1 that cannot be counteracted by Vpx
    • Bloch N., et al. HIV-1 infection of plasmacytoid and myeloid dendritic cells is restricted by high levels of SAMHD1 that cannot be counteracted by Vpx. AIDS Res. Hum. Retroviruses 2013, 10.1089/aid.2013.0119.
    • (2013) AIDS Res. Hum. Retroviruses
    • Bloch, N.1
  • 41
    • 0027180921 scopus 로고
    • Mechanisms for the inhibition of HIV replication by interferons-alpha, -beta, and -gamma in primary human macrophages
    • Meylan P.R., et al. Mechanisms for the inhibition of HIV replication by interferons-alpha, -beta, and -gamma in primary human macrophages. Virology 1993, 193:138-148.
    • (1993) Virology , vol.193 , pp. 138-148
    • Meylan, P.R.1
  • 42
    • 84874163234 scopus 로고    scopus 로고
    • Evidence for IFNalpha-induced, SAMHD1-independent inhibitors of early HIV-1 infection
    • Goujon C., et al. Evidence for IFNalpha-induced, SAMHD1-independent inhibitors of early HIV-1 infection. Retrovirology 2013, 10:23.
    • (2013) Retrovirology , vol.10 , pp. 23
    • Goujon, C.1
  • 43
    • 84886953102 scopus 로고    scopus 로고
    • Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection
    • Goujon C., et al. Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection. Nature 2013, 10.1038/nature12542.
    • (2013) Nature
    • Goujon, C.1
  • 44
    • 77951288057 scopus 로고    scopus 로고
    • HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells
    • Gringhuis S.I., et al. HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells. Nat. Immunol. 2010, 11:419-426.
    • (2010) Nat. Immunol. , vol.11 , pp. 419-426
    • Gringhuis, S.I.1
  • 45
    • 84866488122 scopus 로고    scopus 로고
    • Innate immune recognition of HIV-1
    • Iwasaki A. Innate immune recognition of HIV-1. Immunity 2012, 37:389-398.
    • (2012) Immunity , vol.37 , pp. 389-398
    • Iwasaki, A.1
  • 46
    • 49549100511 scopus 로고    scopus 로고
    • Trex1 prevents cell-intrinsic initiation of autoimmunity
    • Stetson D.B., et al. Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 2008, 134:587-598.
    • (2008) Cell , vol.134 , pp. 587-598
    • Stetson, D.B.1
  • 47
    • 77958114725 scopus 로고    scopus 로고
    • The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
    • Yan N., et al. The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nat. Immunol. 2010, 11:1005-1013.
    • (2010) Nat. Immunol. , vol.11 , pp. 1005-1013
    • Yan, N.1
  • 48
    • 33744832621 scopus 로고    scopus 로고
    • With a little help from a friend: increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIV(MAC)
    • Goujon C., et al. With a little help from a friend: increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIV(MAC). Gene Ther. 2006, 13:991-994.
    • (2006) Gene Ther. , vol.13 , pp. 991-994
    • Goujon, C.1
  • 49
    • 77956497003 scopus 로고    scopus 로고
    • A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells
    • Manel N., et al. A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells. Nature 2010, 467:214-217.
    • (2010) Nature , vol.467 , pp. 214-217
    • Manel, N.1
  • 50
    • 84882896267 scopus 로고    scopus 로고
    • Cyclic GMP-AMP synthase is an innate immune sensor of hiv and other retroviruses
    • Gao D., et al. Cyclic GMP-AMP synthase is an innate immune sensor of hiv and other retroviruses. Science 2013, 341:903-906.
    • (2013) Science , vol.341 , pp. 903-906
    • Gao, D.1
  • 51
    • 17844380477 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
    • Honda K., et al. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 2005, 434:1035-1040.
    • (2005) Nature , vol.434 , pp. 1035-1040
    • Honda, K.1
  • 52
    • 77956689533 scopus 로고    scopus 로고
    • Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3
    • Sasai M., et al. Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. Science 2010, 329:1530-1534.
    • (2010) Science , vol.329 , pp. 1530-1534
    • Sasai, M.1
  • 54
    • 77953272740 scopus 로고    scopus 로고
    • Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses
    • Blanchet F.P., et al. Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity 2010, 32:654-669.
    • (2010) Immunity , vol.32 , pp. 654-669
    • Blanchet, F.P.1
  • 55
    • 61449231643 scopus 로고    scopus 로고
    • DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production
    • Meyer-Wentrup F., et al. DCIR is endocytosed into human dendritic cells and inhibits TLR8-mediated cytokine production. J. Leukoc. Biol. 2009, 85:518-525.
    • (2009) J. Leukoc. Biol. , vol.85 , pp. 518-525
    • Meyer-Wentrup, F.1
  • 56
    • 0037407691 scopus 로고    scopus 로고
    • Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells
    • Kerkmann M., et al. Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J. Immunol. 2003, 170:4465-4474.
    • (2003) J. Immunol. , vol.170 , pp. 4465-4474
    • Kerkmann, M.1
  • 57
    • 33947134377 scopus 로고    scopus 로고
    • Autophagy-dependent viral recognition by plasmacytoid dendritic cells
    • Lee H.K., et al. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007, 315:1398-1401.
    • (2007) Science , vol.315 , pp. 1398-1401
    • Lee, H.K.1
  • 58
    • 84870861513 scopus 로고    scopus 로고
    • Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes
    • Henault J., et al. Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. Immunity 2012, 37:986-997.
    • (2012) Immunity , vol.37 , pp. 986-997
    • Henault, J.1
  • 59
    • 78149442321 scopus 로고    scopus 로고
    • Evidence of dysregulation of dendritic cells in primary HIV infection
    • Sabado R.L., et al. Evidence of dysregulation of dendritic cells in primary HIV infection. Blood 2010, 116:3839-3852.
    • (2010) Blood , vol.116 , pp. 3839-3852
    • Sabado, R.L.1
  • 60
    • 0038142359 scopus 로고    scopus 로고
    • Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1
    • Donaghy H., et al. Dysfunction and infection of freshly isolated blood myeloid and plasmacytoid dendritic cells in patients infected with HIV-1. Blood 2003, 101:4505-4511.
    • (2003) Blood , vol.101 , pp. 4505-4511
    • Donaghy, H.1
  • 61
    • 77952885201 scopus 로고    scopus 로고
    • Impairment of in vitro generation of monocyte-derived human dendritic cells by inactivated human immunodeficiency virus-1: Involvement of type I interferon produced from plasmacytoid dendritc cells
    • Kodama A., et al. Impairment of in vitro generation of monocyte-derived human dendritic cells by inactivated human immunodeficiency virus-1: Involvement of type I interferon produced from plasmacytoid dendritc cells. Hum. Immunol. 2010, 71:541-550.
    • (2010) Hum. Immunol. , vol.71 , pp. 541-550
    • Kodama, A.1
  • 62
    • 84862908654 scopus 로고    scopus 로고
    • Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo
    • Swiecki M., et al. Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo. J. Exp. Med. 2011, 208:2367-2374.
    • (2011) J. Exp. Med. , vol.208 , pp. 2367-2374
    • Swiecki, M.1
  • 63
    • 42649126710 scopus 로고    scopus 로고
    • Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection
    • Dillon S.M., et al. Plasmacytoid and myeloid dendritic cells with a partial activation phenotype accumulate in lymphoid tissue during asymptomatic chronic HIV-1 infection. J. Acquir. Immune Defic. Syndr. 2008, 48:1-12.
    • (2008) J. Acquir. Immune Defic. Syndr. , vol.48 , pp. 1-12
    • Dillon, S.M.1
  • 64
    • 77955249196 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients
    • Lehmann C., et al. Plasmacytoid dendritic cells accumulate and secrete interferon alpha in lymph nodes of HIV-1 patients. PLoS ONE 2010, 5:e11110.
    • (2010) PLoS ONE , vol.5
    • Lehmann, C.1
  • 65
    • 67650351918 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells accumulate in spleens from chronically HIV-infected patients but barely participate in interferon-alpha expression
    • Nascimbeni M., et al. Plasmacytoid dendritic cells accumulate in spleens from chronically HIV-infected patients but barely participate in interferon-alpha expression. Blood 2009, 113:6112-6119.
    • (2009) Blood , vol.113 , pp. 6112-6119
    • Nascimbeni, M.1
  • 66
    • 2342648904 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells
    • Fonteneau J.F., et al. Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells. J. Virol. 2004, 78:5223-5232.
    • (2004) J. Virol. , vol.78 , pp. 5223-5232
    • Fonteneau, J.F.1
  • 67
    • 79961169068 scopus 로고    scopus 로고
    • Dissecting the role of dendritic cells in simian immunodeficiency virus infection and AIDS
    • Wonderlich E.R., et al. Dissecting the role of dendritic cells in simian immunodeficiency virus infection and AIDS. Immunol. Res. 2011, 50:228-234.
    • (2011) Immunol. Res. , vol.50 , pp. 228-234
    • Wonderlich, E.R.1
  • 68
    • 67249117245 scopus 로고    scopus 로고
    • Rapid influx and death of plasmacytoid dendritic cells in lymph nodes mediate depletion in acute simian immunodeficiency virus infection
    • Brown K.N., et al. Rapid influx and death of plasmacytoid dendritic cells in lymph nodes mediate depletion in acute simian immunodeficiency virus infection. PLoS Pathog. 2009, 5:e1000413.
    • (2009) PLoS Pathog. , vol.5
    • Brown, K.N.1
  • 69
    • 78651238652 scopus 로고    scopus 로고
    • Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection
    • Wijewardana V., et al. Early myeloid dendritic cell dysregulation is predictive of disease progression in simian immunodeficiency virus infection. PLoS Pathog. 2010, 6:e1001235.
    • (2010) PLoS Pathog. , vol.6
    • Wijewardana, V.1
  • 70
    • 0024328058 scopus 로고
    • Suppression of immune responses by dendritic cells infected with HIV
    • Macatonia S.E., et al. Suppression of immune responses by dendritic cells infected with HIV. Immunology 1989, 67:285-289.
    • (1989) Immunology , vol.67 , pp. 285-289
    • Macatonia, S.E.1
  • 71
    • 0028652286 scopus 로고
    • Dendritic cells from HIV-1 infected individuals show reduced capacity to stimulate autologous T-cell proliferation
    • Roberts M., et al. Dendritic cells from HIV-1 infected individuals show reduced capacity to stimulate autologous T-cell proliferation. Immunol. Lett. 1994, 43:39-43.
    • (1994) Immunol. Lett. , vol.43 , pp. 39-43
    • Roberts, M.1
  • 72
    • 40949099876 scopus 로고    scopus 로고
    • Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands
    • Martinson J.A., et al. Dendritic cells from HIV-1 infected individuals are less responsive to toll-like receptor (TLR) ligands. Cell. Immunol. 2007, 250:75-84.
    • (2007) Cell. Immunol. , vol.250 , pp. 75-84
    • Martinson, J.A.1
  • 73
    • 72949117233 scopus 로고    scopus 로고
    • The immune response during acute HIV-1 infection: clues for vaccine development
    • McMichael A.J., et al. The immune response during acute HIV-1 infection: clues for vaccine development. Nat. Rev. Immunol. 2010, 10:11-23.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 11-23
    • McMichael, A.J.1
  • 74
    • 79251480064 scopus 로고    scopus 로고
    • Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue
    • Doitsh G., et al. Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Cell 2010, 143:789-801.
    • (2010) Cell , vol.143 , pp. 789-801
    • Doitsh, G.1
  • 75
    • 84879422443 scopus 로고    scopus 로고
    • HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration
    • Cooper A., et al. HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration. Nature 2013, 498:376-379.
    • (2013) Nature , vol.498 , pp. 376-379
    • Cooper, A.1
  • 76
    • 0028912254 scopus 로고
    • Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes
    • Finkel T.H., et al. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat. Med. 1995, 1:129-134.
    • (1995) Nat. Med. , vol.1 , pp. 129-134
    • Finkel, T.H.1
  • 77
    • 84870484583 scopus 로고    scopus 로고
    • HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44
    • Frleta D., et al. HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44. J. Clin. Invest. 2012, 122:4685-4697.
    • (2012) J. Clin. Invest. , vol.122 , pp. 4685-4697
    • Frleta, D.1
  • 78
    • 84873120085 scopus 로고    scopus 로고
    • Plasma factors during chronic HIV-1 infection impair IL-12 secretion by myeloid dendritic cells via a virus-independent pathway
    • Miller E.A., et al. Plasma factors during chronic HIV-1 infection impair IL-12 secretion by myeloid dendritic cells via a virus-independent pathway. J. Acquir. Immune Defic. Syndr. 2012, 61:535-544.
    • (2012) J. Acquir. Immune Defic. Syndr. , vol.61 , pp. 535-544
    • Miller, E.A.1
  • 79
    • 34447534178 scopus 로고    scopus 로고
    • Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1
    • Sabado R.L., et al. Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1. Eur. J. Immunol. 2007, 37:1752-1763.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 1752-1763
    • Sabado, R.L.1
  • 80
    • 1642392156 scopus 로고    scopus 로고
    • DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation
    • Moris A., et al. DC-SIGN promotes exogenous MHC-I-restricted HIV-1 antigen presentation. Blood 2004, 103:2648-2654.
    • (2004) Blood , vol.103 , pp. 2648-2654
    • Moris, A.1
  • 81
    • 80555154835 scopus 로고    scopus 로고
    • HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation
    • Van Montfort T., et al. HIV-1 N-glycan composition governs a balance between dendritic cell-mediated viral transmission and antigen presentation. J. Immunol. 2011, 187:4676-4685.
    • (2011) J. Immunol. , vol.187 , pp. 4676-4685
    • Van Montfort, T.1
  • 82
    • 0035106473 scopus 로고    scopus 로고
    • MHC-I-restricted presentation of HIV-1 virion antigens without viral replication
    • Buseyne F., et al. MHC-I-restricted presentation of HIV-1 virion antigens without viral replication. Nat. Med. 2001, 7:344-349.
    • (2001) Nat. Med. , vol.7 , pp. 344-349
    • Buseyne, F.1
  • 83
    • 34548674705 scopus 로고    scopus 로고
    • Antigen crosspresentation by human plasmacytoid dendritic cells
    • Hoeffel G., et al. Antigen crosspresentation by human plasmacytoid dendritic cells. Immunity 2007, 27:481-492.
    • (2007) Immunity , vol.27 , pp. 481-492
    • Hoeffel, G.1
  • 84
    • 77953484184 scopus 로고    scopus 로고
    • Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells
    • Poulin L.F., et al. Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells. J. Exp. Med. 2010, 207:1261-1271.
    • (2010) J. Exp. Med. , vol.207 , pp. 1261-1271
    • Poulin, L.F.1
  • 86
    • 84879120951 scopus 로고    scopus 로고
    • Networking at the level of host immunity: immune cell interactions during persistent viral infections
    • Ng C.T., et al. Networking at the level of host immunity: immune cell interactions during persistent viral infections. Cell Host Microbe 2013, 13:652-664.
    • (2013) Cell Host Microbe , vol.13 , pp. 652-664
    • Ng, C.T.1
  • 87
    • 84884145979 scopus 로고    scopus 로고
    • Humanized mice for the study of infectious diseases
    • Brehm M.A., et al. Humanized mice for the study of infectious diseases. Curr. Opin. Immunol. 2013, 25:428-435.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 428-435
    • Brehm, M.A.1
  • 88
    • 0041327667 scopus 로고    scopus 로고
    • Persistent immune activation in HIV-1 infection is associated with progression to AIDS
    • Hazenberg M.D., et al. Persistent immune activation in HIV-1 infection is associated with progression to AIDS. AIDS 2003, 17:1881-1888.
    • (2003) AIDS , vol.17 , pp. 1881-1888
    • Hazenberg, M.D.1
  • 89
    • 78049246978 scopus 로고    scopus 로고
    • Biomarkers and HIV-associated cardiovascular disease
    • Baker J.V., Duprez D. Biomarkers and HIV-associated cardiovascular disease. Curr. Opin. HIV AIDS 2010, 5:511-516.
    • (2010) Curr. Opin. HIV AIDS , vol.5 , pp. 511-516
    • Baker, J.V.1    Duprez, D.2
  • 90
    • 84871703067 scopus 로고    scopus 로고
    • Microbial translocation, immune activation, and HIV disease
    • Klatt N.R., et al. Microbial translocation, immune activation, and HIV disease. Trends Microbiol. 2013, 21:6-13.
    • (2013) Trends Microbiol. , vol.21 , pp. 6-13
    • Klatt, N.R.1
  • 91
    • 84866555781 scopus 로고    scopus 로고
    • Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection
    • Klatt N.R., et al. Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection. Mucosal Immunol. 2012, 5:646-657.
    • (2012) Mucosal Immunol. , vol.5 , pp. 646-657
    • Klatt, N.R.1
  • 92
    • 80051798291 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques
    • Kwa S., et al. Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques. Blood 2011, 118:2763-2773.
    • (2011) Blood , vol.118 , pp. 2763-2773
    • Kwa, S.1
  • 93
    • 84867544493 scopus 로고    scopus 로고
    • SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa
    • Reeves R.K., et al. SIV infection induces accumulation of plasmacytoid dendritic cells in the gut mucosa. J. Infect. Dis. 2012, 206:1462-1468.
    • (2012) J. Infect. Dis. , vol.206 , pp. 1462-1468
    • Reeves, R.K.1
  • 94
    • 0025823898 scopus 로고
    • Interferon-alpha and tumor necrosis factor-alpha in serum of patients in various stages of HIV-1 infection
    • von Sydow M., et al. Interferon-alpha and tumor necrosis factor-alpha in serum of patients in various stages of HIV-1 infection. AIDS Res. Hum. Retroviruses 1991, 7:375-380.
    • (1991) AIDS Res. Hum. Retroviruses , vol.7 , pp. 375-380
    • von Sydow, M.1
  • 95
    • 33646468496 scopus 로고    scopus 로고
    • Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients
    • Herbeuval J.P., et al. Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:7000-7005.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 7000-7005
    • Herbeuval, J.P.1
  • 96
    • 72849132344 scopus 로고    scopus 로고
    • Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
    • Bosinger S.E., et al. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J. Clin. Invest. 2009, 119:3556-3572.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3556-3572
    • Bosinger, S.E.1
  • 97
    • 72849136282 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response
    • Jacquelin B., et al. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J. Clin. Invest. 2009, 119:3544-3555.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3544-3555
    • Jacquelin, B.1
  • 98
    • 27744560468 scopus 로고    scopus 로고
    • CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis
    • Herbeuval J.P., et al. CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis. Blood 2005, 106:3524-3531.
    • (2005) Blood , vol.106 , pp. 3524-3531
    • Herbeuval, J.P.1
  • 99
    • 58149184316 scopus 로고    scopus 로고
    • Reversible blockade of thymic output: an inherent part of TLR ligand-mediated immune response
    • Demoulins T., et al. Reversible blockade of thymic output: an inherent part of TLR ligand-mediated immune response. J. Immunol. 2008, 181:6757-6769.
    • (2008) J. Immunol. , vol.181 , pp. 6757-6769
    • Demoulins, T.1
  • 100
    • 0030036342 scopus 로고    scopus 로고
    • Induction of bystander T cell proliferation by viruses and type I interferon in vivo
    • Tough D.F., et al. Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science 1996, 272:1947-1950.
    • (1996) Science , vol.272 , pp. 1947-1950
    • Tough, D.F.1
  • 101
    • 2542481852 scopus 로고    scopus 로고
    • Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo
    • Reed J.R., et al. Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo. J. Exp. Med. 2004, 199:1433-1443.
    • (2004) J. Exp. Med. , vol.199 , pp. 1433-1443
    • Reed, J.R.1
  • 102
    • 38849134878 scopus 로고    scopus 로고
    • Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics
    • Sedaghat A.R., et al. Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon-mediated disruption of T-cell dynamics. J. Virol. 2008, 82:1870-1883.
    • (2008) J. Virol. , vol.82 , pp. 1870-1883
    • Sedaghat, A.R.1
  • 103
    • 84876299371 scopus 로고    scopus 로고
    • Blockade of chronic type I interferon signaling to control persistent LCMV infection
    • Wilson E.B., et al. Blockade of chronic type I interferon signaling to control persistent LCMV infection. Science 2013, 340:202-207.
    • (2013) Science , vol.340 , pp. 202-207
    • Wilson, E.B.1
  • 104
    • 84876311772 scopus 로고    scopus 로고
    • Persistent LCMV infection is controlled by blockade of type I interferon signaling
    • Teijaro J.R., et al. Persistent LCMV infection is controlled by blockade of type I interferon signaling. Science 2013, 340:207-211.
    • (2013) Science , vol.340 , pp. 207-211
    • Teijaro, J.R.1
  • 105
    • 84879300349 scopus 로고    scopus 로고
    • The immunological synapse: the gateway to the HIV reservoir
    • Kulpa D.A., et al. The immunological synapse: the gateway to the HIV reservoir. Immunol. Rev. 2013, 254:305-325.
    • (2013) Immunol. Rev. , vol.254 , pp. 305-325
    • Kulpa, D.A.1
  • 106
    • 84867521316 scopus 로고    scopus 로고
    • Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome
    • Handley S.A., et al. Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome. Cell 2012, 151:253-266.
    • (2012) Cell , vol.151 , pp. 253-266
    • Handley, S.A.1
  • 107
    • 84883860231 scopus 로고    scopus 로고
    • SIV-induced instability of the chimpanzee gut microbiome
    • Moeller A.H., et al. SIV-induced instability of the chimpanzee gut microbiome. Cell Host Microbe 2013, 14:340-345.
    • (2013) Cell Host Microbe , vol.14 , pp. 340-345
    • Moeller, A.H.1
  • 108
    • 84883821864 scopus 로고    scopus 로고
    • Blocking TLR7- and TLR9-mediated IFN-alpha production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection
    • Kader M., et al. Blocking TLR7- and TLR9-mediated IFN-alpha production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection. PLoS Pathog. 2013, 9:e1003530.
    • (2013) PLoS Pathog. , vol.9
    • Kader, M.1
  • 109
    • 61449115882 scopus 로고    scopus 로고
    • Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection
    • Favre D., et al. Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. PLoS Pathog. 2009, 5:e1000295.
    • (2009) PLoS Pathog. , vol.5
    • Favre, D.1
  • 110
    • 33750364462 scopus 로고    scopus 로고
    • Do regulatory T-cells play a role in AIDS pathogenesis?
    • Boasso A., et al. Do regulatory T-cells play a role in AIDS pathogenesis?. AIDS Rev. 2006, 8:141-147.
    • (2006) AIDS Rev. , vol.8 , pp. 141-147
    • Boasso, A.1
  • 111
    • 43049101640 scopus 로고    scopus 로고
    • The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
    • Guo B., et al. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest. 2008, 118:1680-1690.
    • (2008) J. Clin. Invest. , vol.118 , pp. 1680-1690
    • Guo, B.1
  • 112
    • 19344377474 scopus 로고    scopus 로고
    • GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
    • Munn D.H., et al. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity 2005, 22:633-642.
    • (2005) Immunity , vol.22 , pp. 633-642
    • Munn, D.H.1
  • 113
    • 77952977625 scopus 로고    scopus 로고
    • Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease
    • Favre D., et al. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Sci. Transl. Med. 2010, 2:32ra36.
    • (2010) Sci. Transl. Med. , vol.2
    • Favre, D.1
  • 114
    • 58149380860 scopus 로고    scopus 로고
    • Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression
    • Malleret B., et al. Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression. Blood 2008, 112:4598-4608.
    • (2008) Blood , vol.112 , pp. 4598-4608
    • Malleret, B.1
  • 115
    • 55849140547 scopus 로고    scopus 로고
    • HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism
    • Manches O., et al. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism. J. Clin. Invest. 2008, 118:3431-3439.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3431-3439
    • Manches, O.1
  • 116
    • 84865546531 scopus 로고    scopus 로고
    • Activation of the noncanonical NF-kappaB pathway by HIV controls a dendritic cell immunoregulatory phenotype
    • Manches O., et al. Activation of the noncanonical NF-kappaB pathway by HIV controls a dendritic cell immunoregulatory phenotype. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:14122-14127.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 14122-14127
    • Manches, O.1
  • 117
    • 70149101645 scopus 로고    scopus 로고
    • IDO activates regulatory T cells and blocks their conversion into Th17-like T cells
    • Baban B., et al. IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J. Immunol. 2009, 183:2475-2483.
    • (2009) J. Immunol. , vol.183 , pp. 2475-2483
    • Baban, B.1
  • 118
    • 67650351923 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes
    • Sharma M.D., et al. Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes. Blood 2009, 113:6102-6111.
    • (2009) Blood , vol.113 , pp. 6102-6111
    • Sharma, M.D.1
  • 119
    • 84255215466 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo
    • Takagi H., et al. Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo. Immunity 2011, 35:958-971.
    • (2011) Immunity , vol.35 , pp. 958-971
    • Takagi, H.1
  • 120
    • 79953738488 scopus 로고    scopus 로고
    • HIV-associated immune activation: from bench to bedside
    • d'Ettorre G., et al. HIV-associated immune activation: from bench to bedside. AIDS Res. Hum. Retroviruses 2011, 27:355-364.
    • (2011) AIDS Res. Hum. Retroviruses , vol.27 , pp. 355-364
    • d'Ettorre, G.1
  • 121
    • 33745960966 scopus 로고    scopus 로고
    • Use of etanercept in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients
    • Ting P.T., Koo J.Y. Use of etanercept in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients. Int. J. Dermatol. 2006, 45:689-692.
    • (2006) Int. J. Dermatol. , vol.45 , pp. 689-692
    • Ting, P.T.1    Koo, J.Y.2
  • 122
    • 84872037286 scopus 로고    scopus 로고
    • A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication
    • Garcia F., et al. A dendritic cell-based vaccine elicits T cell responses associated with control of HIV-1 replication. Sci. Transl. Med. 2013, 5:166ra162.
    • (2013) Sci. Transl. Med. , vol.5
    • Garcia, F.1
  • 123
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Barber D.L., et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006, 439:682-687.
    • (2006) Nature , vol.439 , pp. 682-687
    • Barber, D.L.1
  • 124
    • 84860584561 scopus 로고    scopus 로고
    • PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques
    • Dyavar Shetty R., et al. PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques. J. Clin. Invest. 2012, 122:1712-1716.
    • (2012) J. Clin. Invest. , vol.122 , pp. 1712-1716
    • Dyavar Shetty, R.1
  • 125
    • 70350343544 scopus 로고    scopus 로고
    • Induction of intestinal Th17 cells by segmented filamentous bacteria
    • Ivanov I.I., et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009, 139:485-498.
    • (2009) Cell , vol.139 , pp. 485-498
    • Ivanov, I.I.1


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