Plasmacytoid Dendritic Cells Are Crucial for the Initiation of Inflammation and T Cell Immunity In Vivo

Immunity

Volumn 35, Issue 6, 2011, Pages 958-971

  Takagi, Hideaki ^a   Fukaya, Tomohiro ^a   Eizumi, Kawori ^a   Sato, Yumiko ^a   Sato, Kaori ^a   Shibazaki, Azusa ^a   Otsuka, Haruna ^a   Hijikata, Atsushi ^a   Watanabe, Takashi ^a   Ohara, Osamu ^a   Kaisho, Tsuneyasu ^b   Malissen, Bernard ^c   Sato, Katsuaki ^a,d  

^a RIKEN Center for Integrative Medical Sciences   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; TOLL LIKE RECEPTOR;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; HOMEOSTASIS; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; VIRUS INFECTION;

ABLATION TECHNIQUES; ANIMALS; ANTIGENS; BACTERIAL INFECTIONS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; HERPES SIMPLEX; HOMEOSTASIS; IMMUNITY, CELLULAR; INFLAMMATION; LECTINS; MICE; MICE, INBRED C57BL; PHENOTYPE; RECEPTORS, CELL SURFACE; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TOLL-LIKE RECEPTORS;

EID: 84255215466     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2011.10.014     Document Type: Article

References (37)

1. + T cell expansion with variable dependence on type I IFN. J. Exp. Med. 2004, 199:775-784.
2. Asselin-Paturel C., Boonstra A., Dalod M., Durand I., Yessaad N., Dezutter-Dambuyant C., Vicari A., O'Garra A., Biron C., Brière F., Trinchieri G. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2001, 2:1144-1150.
3. Asselin-Paturel C., Brizard G., Pin J.J., Brière F., Trinchieri G. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol. 2003, 171:6466-6477.
4. Blasius A.L., Colonna M. Sampling and signaling in plasmacytoid dendritic cells: the potential roles of Siglec-H. Trends Immunol. 2006, 27:255-260.
5. Darrasse-Jèze G., Deroubaix S., Mouquet H., Victora G.D., Eisenreich T., Yao K.H., Masilamani R.F., Dustin M.L., Rudensky A., Liu K., Nussenzweig M.C. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J. Exp. Med. 2009, 206:1853-1862.
6. de Heer H.J., Hammad H., Soullié T., Hijdra D., Vos N., Willart M.A., Hoogsteden H.C., Lambrecht B.N. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 2004, 200:89-98.
7. Dudziak D., Kamphorst A.O., Heidkamp G.F., Buchholz V.R., Trumpfheller C., Yamazaki S., Cheong C., Liu K., Lee H.W., Park C.G., et al. Differential antigen processing by dendritic cell subsets in vivo. Science 2007, 315:107-111.
8. Efron P.A., Martins A., Minnich D., Tinsley K., Ungaro R., Bahjat F.R., Hotchkiss R., Clare-Salzler M., Moldawer L.L. Characterization of the systemic loss of dendritic cells in murine lymph nodes during polymicrobial sepsis. J. Immunol. 2004, 173:3035-3043.
9. Fujita S., Seino K., Sato K., Sato Y., Eizumi K., Yamashita N., Taniguchi M., Sato K. Regulatory dendritic cells act as regulators of acute lethal systemic inflammatory response. Blood 2006, 107:3656-3664.
10. + regulatory T cells in the establishment of oral tolerance. Blood 2010, 116:2266-2276.
11. Gilliet M., Cao W., Liu Y.J. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat. Rev. Immunol. 2008, 8:594-606.
12. Goubier A., Dubois B., Gheit H., Joubert G., Villard-Truc F., Asselin-Paturel C., Trinchieri G., Kaiserlian D. Plasmacytoid dendritic cells mediate oral tolerance. Immunity 2008, 29:464-475.
13. + dendritic cells in cytotoxic T cell immunity. Science 2008, 322:1097-1100.
14. +) T cell tolerance. Nat. Immunol. 2010, 11:512-519.
15. Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., Taniguchi T. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature 2005, 434:772-777.
16. Hoshino K., Sugiyama T., Matsumoto M., Tanaka T., Saito M., Hemmi H., Ohara O., Akira S., Kaisho T. IkappaB kinase-α is critical for interferon-α production induced by Toll-like receptors 7 and 9. Nature 2006, 440:949-953.
17. Irla M., Küpfer N., Suter T., Lissilaa R., Benkhoucha M., Skupsky J., Lalive P.H., Fontana A., Reith W., Hugues S. MHC class II-restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell-mediated autoimmunity. J. Exp. Med. 2010, 207:1891-1905.
18. + T cells by exogenous cell-associated antigens. Immunity 2002, 17:211-220.
19. Kaisho T., Tanaka T. Turning NF-kappaB and IRFs on and off in DC. Trends Immunol. 2008, 29:329-336.
20. Kissenpfennig A., Henri S., Dubois B., Laplace-Builhé C., Perrin P., Romani N., Tripp C.H., Douillard P., Leserman L., Kaiserlian D., et al. Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 2005, 22:643-654.
21. Kretschmer K., Apostolou I., Hawiger D., Khazaie K., Nussenzweig M.C., von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat. Immunol. 2005, 6:1219-1227.
22. Kuwajima S., Sato T., Ishida K., Tada H., Tezuka H., Ohteki T. Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation. Nat. Immunol. 2006, 7:740-746.
23. Mouriès J., Moron G., Schlecht G., Escriou N., Dadaglio G., Leclerc C. Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. Blood 2008, 112:3713-3722.
24. + dendritic cells are required for efficient entry of Listeria monocytogenes into the spleen. Immunity 2006, 25:619-630.
25. Ochando J.C., Homma C., Yang Y., Hidalgo A., Garin A., Tacke F., Angeli V., Li Y., Boros P., Ding Y., et al. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat. Immunol. 2006, 7:652-662.
26. Ohnmacht C., Pullner A., King S.B., Drexler I., Meier S., Brocker T., Voehringer D. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J. Exp. Med. 2009, 206:549-559.
27. Proietto A.I., van Dommelen S., Zhou P., Rizzitelli A., D'Amico A., Steptoe R.J., Naik S.H., Lahoud M.H., Liu Y., Zheng P., et al. Dendritic cells in the thymus contribute to T-regulatory cell induction. Proc. Natl. Acad. Sci. USA 2008, 105:19869-19874.
28. Salio M., Palmowski M.J., Atzberger A., Hermans I.F., Cerundolo V. CpG-matured murine plasmacytoid dendritic cells are capable of in vivo priming of functional CD8 T cell responses to endogenous but not exogenous antigens. J. Exp. Med. 2004, 199:567-579.
29. Shen H., Iwasaki A. A crucial role for plasmacytoid dendritic cells in antiviral protection by CpG ODN-based vaginal microbicide. J. Clin. Invest. 2006, 116:2237-2243.
30. Shinohara M.L., Kim J.H., Garcia V.A., Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008, 29:68-78.
31. Swiecki M., Colonna M. Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance. Immunol. Rev. 2010, 234:142-162.
32. + T cell accrual. Immunity 2010, 33:955-966.
33. Villadangos J.A., Young L. Antigen-presentation properties of plasmacytoid dendritic cells. Immunity 2008, 29:352-361.
34. + regulatory T cells. J. Immunol. 2008, 180:1565-1575.
35. Yoneyama H., Matsuno K., Toda E., Nishiwaki T., Matsuo N., Nakano A., Narumi S., Lu B., Gerard C., Ishikawa S., Matsushima K. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J. Exp. Med. 2005, 202:425-435.
36. Zammit D.J., Cauley L.S., Pham Q.M., Lefrançois L. Dendritic cells maximize the memory CD8 T cell response to infection. Immunity 2005, 22:561-570.
37. Zhang J., Raper A., Sugita N., Hingorani R., Salio M., Palmowski M.J., Cerundolo V., Crocker P.R. Characterization of Siglec-H as a novel endocytic receptor expressed on murine plasmacytoid dendritic cell precursors. Blood 2006, 107:3600-3608.