Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions

Journal of Clinical Investigation

Volumn 115, Issue 11, 2005, Pages 3265-3275

  Beignon, Anne Sophie ^a,d   McKenna, Kelli ^a   Skoberne, Mojca ^a   Manches, Olivier ^b   DaSilva, Ida ^a   Kavanagh, Daniel G ^b   Larsson, Marie ^a,e   Gorelick, Robert J ^c   Lifson, Jeffrey D ^c   Bhardwaj, Nina ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c SAIC FREDERICK INC   (United States)

^d INSTITUT PASTEUR   (France)

^e University of Health Science   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; GENOMIC RNA; GLYCOPROTEIN GP 160; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENDOCYTOSIS; ENDOSOME; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETIC COMPLEMENTATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IN VITRO STUDY; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN RNA BINDING; VIRUS ENVELOPE; VIRUS LOAD;

ANTIGENS, CD4; CELLS, CULTURED; DENDRITIC CELLS; ENDOCYTOSIS; HIV ENVELOPE PROTEIN GP160; HIV INFECTIONS; HIV-1; HUMANS; RNA, VIRAL; TOLL-LIKE RECEPTORS;

EID: 27644513772     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI26032     Document Type: Article

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