GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase

Immunity

Volumn 22, Issue 5, 2005, Pages 633-642

  Munn, David H ^a   Sharma, Madhav D ^a   Baban, Babak ^a   Harding, Heather P ^b   Zhang, Yuhong ^b   Ron, David ^b   Mellor, Andrew L ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GCN2 KINASE; INDOLEAMINE 2,3 DIOXYGENASE; PHOSPHOTRANSFERASE; TRANSFER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DISRUPTION; CELL PROLIFERATION; CELLULAR IMMUNITY; CLONAL ANERGY; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; T LYMPHOCYTE; WILD TYPE;

ADOPTIVE TRANSFER; ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL PROLIFERATION; CLONAL ANERGY; DENDRITIC CELLS; ENZYME ACTIVATION; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TRYPTOPHAN; TRYPTOPHAN OXYGENASE;

EID: 19344377474     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2005.03.013     Document Type: Article

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