Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

Nature

Volumn 474, Issue 7353, 2011, Pages 658-661

  Hrecka, Kasia ^a,b   Hao, Caili ^a   Gierszewska, Magda ^b   Swanson, Selene K ^c   Kesik Brodacka, Malgorzata ^a,f   Srivastava, Smita ^b,e   Florens, Laurence ^c   Washburn, Michael P ^c,d   Skowronski, Jacek ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^e New York School of Medicine   (United States)

^f INDUSTRIAL CHEMISTRY RESEARCH INSTITUTE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; COMPLEMENTARY DNA; MONOKINE; PROTEIN; PROTEIN SAMHD1; PROTEIN VPX; RECOMBINANT PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ADAPTATION; HOST-PATHOGEN INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; INFECTIVITY; INHIBITION; MUTATION; PATHOGEN; PROTEIN; VIRUS;

AICARDI GOUTIERES SYNDROME; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS 2; INNATE IMMUNITY; MACROPHAGE; MOLECULAR SENSOR; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS INHIBITION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS; VIRION; VIRUS MUTATION;

CARRIER PROTEINS; CELLS, CULTURED; HEK293 CELLS; HIV INFECTIONS; HIV-1; HUMANS; MACROPHAGES; MONOMERIC GTP-BINDING PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; UBIQUITIN-PROTEIN LIGASES; VIRAL REGULATORY AND ACCESSORY PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; LENTIVIRUS; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 79959858243     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10195     Document Type: Article

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