MHC-I-restricted presentation of HIV-1 virion antigens without viral replication

Nature Medicine

Volumn 7, Issue 3, 2001, Pages 344-349

  Buseyne, Florence ^a   Gall, Sylvie Le ^a   Boccaccio, Claire ^b   Abastado, Jean Pierre ^b   Lifson, Jeffrey D ^c   Arthur, Larry O ^c   Rivière, Yves ^a   Heard, Jean Michel ^a   Schwartz, Olivier ^a  

^a INSTITUT PASTEUR   (France)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS ANTIGEN; VIRUS PROTEIN; VIRUS VACCINE;

ANTIGEN PRESENTATION; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; T LYMPHOCYTE ACTIVATION; VIRION; VIRUS ENVELOPE; VIRUS INFECTION; VIRUS REPLICATION;

CELL LINE; CROSS REACTIONS; EPITOPES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV ANTIGENS; HIV-1; HUMANS; VIRION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0035106473     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/85493     Document Type: Article

References (45)

1. A new foreign policy: MHC class I molecules monitor the outside world
2. MHC class I-restricted CTL responses to exogenous antigens
3. 8+ T cell responses to infectious agents, tumors, transplants, and vaccines
4. Mechanisms of antigen uptake for presentation
5. Capture and processing of exogenous antigens for presentation on MHC molecules
6. A phagosome to cytosol pathway for exogenous antigens presented on MHC class I molecules
7. Cross-presentation of glycoprotein 96-associated antigens on major histocompatibility complex class I molecules requires receptor-mediated endocytosis
8. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways
9. Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization
10. Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells
11. Recycling MHC class I molecules and endosomal peptide loading
12. Dendritic cells and the control of immunity
13. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
14. Cytotoxic T-cell immunity to virus-infected non-hematopoietic cells requires presentation of exogenous antigen
15. Cells process exogenous proteins for recognition by cytotoxic T lymphocytes
16. Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation
17. Dendritic cells and the replication of HIV-1
18. Bone marrow-derived dendritic cells, infection with human immunodeficiency virus, and immunopathology
19. Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors
20. Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors
21. Virus interactions with dendritic cells
22. Virus replication begins in dendritic cells during the transmission of HIV-1 from mature dendritic cells to T cells
23. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
24. Fusion of monocytes and macrophages with HIV-1 correlates with biochemical properties of CXCR4 and CCR5
25. Pseudotyping HIV-1 by the glycoprotein of VSV targets HIV-1 entry to an endocytic pathway and suppresses both the requirement for Nef and the sensitivity to cyclosporin A
26. Efficient lysis of Human Immunodeficiency Virus type 1-infected cells by cytotoxic T lymphocytes
27. In vivo gene delivery and stable transduction of non dividing cells by a lentiviral vector
28. Inactivation of human immunodeficiency virus type 1 infectivity with preservation of conformational and functional integrity of virion surface proteins
29. Chemical inactivation of retroviral infectivity by targeting nucleocapsid protein zinc fingers: A candidate SIV vaccine
30. Target cell-specific determinants of membrane fusion within the Human Immunodeficiency virus type 1 gp120 third variable region and gp41 amino terminus
31. A fusion-defective mutant of the Vesicular Stomatitis Virus glycoprotein
32. + cells
33. High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR
34. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS
35. Antiviral activity of the proteasome on incoming HIV-1
36. Endocytosis of MHC-I molecules is induced by HIV-1 Nef
37. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes
38. Env-specific cytotoxic T lymphocytes responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids
39. HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women
40. Role of cellular immunity in protection against HIV infection
41. T lymphocyte responses in HIV-1 infection: Implications for vaccine development
42. Monocyte-derived dendritic cells: Development of a cellular processor for clinical applications
43. Cross-clade-specific cytotoxic T lymphocytes in HIV-1-infected children
44. Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by Human Immunodeficiency Virus type 1
45. Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells