-
1
-
-
84877152391
-
Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity
-
M.E. Ackerman, M. Crispin, X. Yu, K. Baruah, A.W. Boesch, D.J. Harvey, A.S. Dugast, E.L. Heizen, A. Ercan, and I. Choi Natural variation in Fc glycosylation of HIV-specific antibodies impacts antiviral activity J. Clin. Invest. 123 2013 2183 2192
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 2183-2192
-
-
Ackerman, M.E.1
Crispin, M.2
Yu, X.3
Baruah, K.4
Boesch, A.W.5
Harvey, D.J.6
Dugast, A.S.7
Heizen, E.L.8
Ercan, A.9
Choi, I.10
-
2
-
-
84877316930
-
Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for FcγR2a and FcγR2b
-
M.E. Ackerman, A.S. Dugast, E.G. McAndrew, S. Tsoukas, A.F. Licht, D.J. Irvine, and G. Alter Enhanced Phagocytic Activity of HIV-Specific Antibodies Correlates with Natural Production of Immunoglobulins with Skewed Affinity for FcγR2a and FcγR2b J. Virol. 87 2013 5468 5476
-
(2013)
J. Virol.
, vol.87
, pp. 5468-5476
-
-
Ackerman, M.E.1
Dugast, A.S.2
McAndrew, E.G.3
Tsoukas, S.4
Licht, A.F.5
Irvine, D.J.6
Alter, G.7
-
3
-
-
0021225388
-
Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence
-
R. Ahmed, A. Salmi, L.D. Butler, J.M. Chiller, and M.B. Oldstone Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence J. Exp. Med. 160 1984 521 540
-
(1984)
J. Exp. Med.
, vol.160
, pp. 521-540
-
-
Ahmed, R.1
Salmi, A.2
Butler, L.D.3
Chiller, J.M.4
Oldstone, M.B.5
-
4
-
-
77953216462
-
IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection
-
G. Alter, D. Kavanagh, S. Rihn, R. Luteijn, D. Brooks, M. Oldstone, J. van Lunzen, and M. Altfeld IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection J. Clin. Invest. 120 2010 1905 1913
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1905-1913
-
-
Alter, G.1
Kavanagh, D.2
Rihn, S.3
Luteijn, R.4
Brooks, D.5
Oldstone, M.6
Van Lunzen, J.7
Altfeld, M.8
-
5
-
-
38549149823
-
Immune activation and inflammation in HIV-1 infection: Causes and consequences
-
V. Appay, and D. Sauce Immune activation and inflammation in HIV-1 infection: causes and consequences J. Pathol. 214 2008 231 241
-
(2008)
J. Pathol.
, vol.214
, pp. 231-241
-
-
Appay, V.1
Sauce, D.2
-
6
-
-
33746218615
-
Cytotoxic CD4 T cells in viral hepatitis
-
N. Aslan, C. Yurdaydin, J. Wiegand, T. Greten, A. Ciner, M.F. Meyer, H. Heiken, B. Kuhlmann, T. Kaiser, and H. Bozkaya Cytotoxic CD4 T cells in viral hepatitis J. Viral Hepat. 13 2006 505 514
-
(2006)
J. Viral Hepat.
, vol.13
, pp. 505-514
-
-
Aslan, N.1
Yurdaydin, C.2
Wiegand, J.3
Greten, T.4
Ciner, A.5
Meyer, M.F.6
Heiken, H.7
Kuhlmann, B.8
Kaiser, T.9
Bozkaya, H.10
-
7
-
-
84855485734
-
Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection
-
R.D. Aubert, A.O. Kamphorst, S. Sarkar, V. Vezys, S.J. Ha, D.L. Barber, L. Ye, A.H. Sharpe, G.J. Freeman, and R. Ahmed Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection Proc. Natl. Acad. Sci. USA 108 2011 21182 21187
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 21182-21187
-
-
Aubert, R.D.1
Kamphorst, A.O.2
Sarkar, S.3
Vezys, V.4
Ha, S.J.5
Barber, D.L.6
Ye, L.7
Sharpe, A.H.8
Freeman, G.J.9
Ahmed, R.10
-
8
-
-
84871797372
-
Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration
-
L. Azzoni, A.S. Foulkes, E. Papasavvas, A.M. Mexas, K.M. Lynn, K. Mounzer, P. Tebas, J.M. Jacobson, I. Frank, and M.P. Busch Pegylated Interferon alfa-2a monotherapy results in suppression of HIV type 1 replication and decreased cell-associated HIV DNA integration J. Infect. Dis. 207 2013 213 222
-
(2013)
J. Infect. Dis.
, vol.207
, pp. 213-222
-
-
Azzoni, L.1
Foulkes, A.S.2
Papasavvas, E.3
Mexas, A.M.4
Lynn, K.M.5
Mounzer, K.6
Tebas, P.7
Jacobson, J.M.8
Frank, I.9
Busch, M.P.10
-
9
-
-
34250787647
-
Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections
-
M.F. Bachmann, P. Wolint, S. Walton, K. Schwarz, and A. Oxenius Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections Eur. J. Immunol. 37 2007 1502 1512
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 1502-1512
-
-
Bachmann, M.F.1
Wolint, P.2
Walton, S.3
Schwarz, K.4
Oxenius, A.5
-
10
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
D.L. Barber, E.J. Wherry, D. Masopust, B. Zhu, J.P. Allison, A.H. Sharpe, G.J. Freeman, and R. Ahmed Restoring function in exhausted CD8 T cells during chronic viral infection Nature 439 2006 682 687
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
11
-
-
34249005003
-
Herpesvirus latency confers symbiotic protection from bacterial infection
-
E.S. Barton, D.W. White, J.S. Cathelyn, K.A. Brett-McClellan, M. Engle, M.S. Diamond, V.L. Miller, and H.W. Virgin 4th Herpesvirus latency confers symbiotic protection from bacterial infection Nature 447 2007 326 329
-
(2007)
Nature
, vol.447
, pp. 326-329
-
-
Barton, E.S.1
White, D.W.2
Cathelyn, J.S.3
Brett-Mcclellan, K.A.4
Engle, M.5
Diamond, M.S.6
Miller, V.L.7
Virgin IV, H.W.8
-
12
-
-
0028298652
-
Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice
-
M. Battegay, D. Moskophidis, A. Rahemtulla, H. Hengartner, T.W. Mak, and R.M. Zinkernagel Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice J. Virol. 68 1994 4700 4704
-
(1994)
J. Virol.
, vol.68
, pp. 4700-4704
-
-
Battegay, M.1
Moskophidis, D.2
Rahemtulla, A.3
Hengartner, H.4
Mak, T.W.5
Zinkernagel, R.M.6
-
13
-
-
33645796485
-
Specific remodeling of splenic architecture by cytomegalovirus
-
C.A. Benedict, C. De Trez, K. Schneider, S. Ha, G. Patterson, and C.F. Ware Specific remodeling of splenic architecture by cytomegalovirus PLoS Pathog. 2 2006 e16
-
(2006)
PLoS Pathog.
, vol.2
, pp. 16
-
-
Benedict, C.A.1
De Trez, C.2
Schneider, K.3
Ha, S.4
Patterson, G.5
Ware, C.F.6
-
14
-
-
0034688296
-
Defining parameters for successful immunocytotherapy of persistent viral infection
-
D.P. Berger, D. Homann, and M.B. Oldstone Defining parameters for successful immunocytotherapy of persistent viral infection Virology 266 2000 257 263
-
(2000)
Virology
, vol.266
, pp. 257-263
-
-
Berger, D.P.1
Homann, D.2
Oldstone, M.B.3
-
15
-
-
0033587636
-
Lymphotoxin-beta-deficient mice show defective antiviral immunity
-
D.P. Berger, D. Naniche, M.T. Crowley, P.A. Koni, R.A. Flavell, and M.B. Oldstone Lymphotoxin-beta-deficient mice show defective antiviral immunity Virology 260 1999 136 147
-
(1999)
Virology
, vol.260
, pp. 136-147
-
-
Berger, D.P.1
Naniche, D.2
Crowley, M.T.3
Koni, P.A.4
Flavell, R.A.5
Oldstone, M.B.6
-
16
-
-
78650726071
-
Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression
-
A. Bergthaler, L. Flatz, A.N. Hegazy, S. Johnson, E. Horvath, M. Löhning, and D.D. Pinschewer Viral replicative capacity is the primary determinant of lymphocytic choriomeningitis virus persistence and immunosuppression Proc. Natl. Acad. Sci. USA 107 2010 21641 21646
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 21641-21646
-
-
Bergthaler, A.1
Flatz, L.2
Hegazy, A.N.3
Johnson, S.4
Horvath, E.5
Löhning, M.6
Pinschewer, D.D.7
-
17
-
-
54449088740
-
Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade
-
S.D. Blackburn, H. Shin, G.J. Freeman, and E.J. Wherry Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade Proc. Natl. Acad. Sci. USA 105 2008 15016 15021
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15016-15021
-
-
Blackburn, S.D.1
Shin, H.2
Freeman, G.J.3
Wherry, E.J.4
-
18
-
-
57849168934
-
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
-
S.D. Blackburn, H. Shin, W.N. Haining, T. Zou, C.J. Workman, A. Polley, M.R. Betts, G.J. Freeman, D.A. Vignali, and E.J. Wherry Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection Nat. Immunol. 10 2009 29 37
-
(2009)
Nat. Immunol.
, vol.10
, pp. 29-37
-
-
Blackburn, S.D.1
Shin, H.2
Haining, W.N.3
Zou, T.4
Workman, C.J.5
Polley, A.6
Betts, M.R.7
Freeman, G.J.8
Vignali, D.A.9
Wherry, E.J.10
-
19
-
-
84866928409
-
Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection
-
A.L. Blasius, P. Krebs, B.M. Sullivan, M.B. Oldstone, and D.L. Popkin Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection PLoS Pathog. 8 2012 e1002915
-
(2012)
PLoS Pathog.
, vol.8
, pp. 1002915
-
-
Blasius, A.L.1
Krebs, P.2
Sullivan, B.M.3
Oldstone, M.B.4
Popkin, D.L.5
-
20
-
-
80051786980
-
Generalized immune activation and innate immune responses in simian immunodeficiency virus infection
-
S.E. Bosinger, D.L. Sodora, and G. Silvestri Generalized immune activation and innate immune responses in simian immunodeficiency virus infection Curr Opin HIV AIDS 6 2011 411 418
-
(2011)
Curr Opin HIV AIDS
, vol.6
, pp. 411-418
-
-
Bosinger, S.E.1
Sodora, D.L.2
Silvestri, G.3
-
21
-
-
67651087322
-
IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells
-
M.A. Brockman, D.S. Kwon, D.P. Tighe, D.F. Pavlik, P.C. Rosato, J. Sela, F. Porichis, S. Le Gall, M.T. Waring, and K. Moss IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells Blood 114 2009 346 356
-
(2009)
Blood
, vol.114
, pp. 346-356
-
-
Brockman, M.A.1
Kwon, D.S.2
Tighe, D.P.3
Pavlik, D.F.4
Rosato, P.C.5
Sela, J.6
Porichis, F.7
Le Gall, S.8
Waring, M.T.9
Moss, K.10
-
22
-
-
58149484842
-
IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection
-
D.G. Brooks, S.J. Ha, H. Elsaesser, A.H. Sharpe, G.J. Freeman, and M.B. Oldstone IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection Proc. Natl. Acad. Sci. USA 105 2008 20428 20433
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20428-20433
-
-
Brooks, D.G.1
Ha, S.J.2
Elsaesser, H.3
Sharpe, A.H.4
Freeman, G.J.5
Oldstone, M.B.6
-
23
-
-
41149130734
-
IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection
-
D.G. Brooks, A.M. Lee, H. Elsaesser, D.B. McGavern, and M.B. Oldstone IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection J. Exp. Med. 205 2008 533 541
-
(2008)
J. Exp. Med.
, vol.205
, pp. 533-541
-
-
Brooks, D.G.1
Lee, A.M.2
Elsaesser, H.3
McGavern, D.B.4
Oldstone, M.B.5
-
24
-
-
33745205112
-
Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection
-
D.G. Brooks, D.B. McGavern, and M.B. Oldstone Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection J. Clin. Invest. 116 2006 1675 1685
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1675-1685
-
-
Brooks, D.G.1
McGavern, D.B.2
Oldstone, M.B.3
-
25
-
-
23244463393
-
Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection
-
D.G. Brooks, L. Teyton, M.B. Oldstone, and D.B. McGavern Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection J. Virol. 79 2005 10514 10527
-
(2005)
J. Virol.
, vol.79
, pp. 10514-10527
-
-
Brooks, D.G.1
Teyton, L.2
Oldstone, M.B.3
McGavern, D.B.4
-
26
-
-
33750499311
-
Interleukin-10 determines viral clearance or persistence in vivo
-
D.G. Brooks, M.J. Trifilo, K.H. Edelmann, L. Teyton, D.B. McGavern, and M.B. Oldstone Interleukin-10 determines viral clearance or persistence in vivo Nat. Med. 12 2006 1301 1309
-
(2006)
Nat. Med.
, vol.12
, pp. 1301-1309
-
-
Brooks, D.G.1
Trifilo, M.J.2
Edelmann, K.H.3
Teyton, L.4
McGavern, D.B.5
Oldstone, M.B.6
-
27
-
-
84867630116
-
A Blueprint for HIV Vaccine Discovery
-
D.R. Burton, R. Ahmed, D.H. Barouch, S.T. Butera, S. Crotty, A. Godzik, D.E. Kaufmann, M.J. McElrath, M.C. Nussenzweig, and B. Pulendran A Blueprint for HIV Vaccine Discovery Cell Host Microbe 12 2012 396 407
-
(2012)
Cell Host Microbe
, vol.12
, pp. 396-407
-
-
Burton, D.R.1
Ahmed, R.2
Barouch, D.H.3
Butera, S.T.4
Crotty, S.5
Godzik, A.6
Kaufmann, D.E.7
McElrath, M.J.8
Nussenzweig, M.C.9
Pulendran, B.10
-
28
-
-
33646174117
-
Cooperation between CD4+ and CD8+ T cells: When, where, and how
-
F. Castellino, and R.N. Germain Cooperation between CD4+ and CD8+ T cells: when, where, and how Annu. Rev. Immunol. 24 2006 519 540
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 519-540
-
-
Castellino, F.1
Germain, R.N.2
-
29
-
-
33646174117
-
Cooperation between CD4+ and CD8+ T cells: When, where, and how
-
F. Castellino, and R.N. Germain Cooperation between CD4+ and CD8+ T cells: when, where, and how Annu. Rev. Immunol. 24 2006 519 540
-
(2006)
Annu. Rev. Immunol.
, vol.24
, pp. 519-540
-
-
Castellino, F.1
Germain, R.N.2
-
30
-
-
84857426963
-
Plasmacytoid dendritic cells control T-cell response to chronic viral infection
-
L. Cervantes-Barragan, K.L. Lewis, S. Firner, V. Thiel, S. Hugues, W. Reith, B. Ludewig, and B. Reizis Plasmacytoid dendritic cells control T-cell response to chronic viral infection Proc. Natl. Acad. Sci. USA 109 2012 3012 3017
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 3012-3017
-
-
Cervantes-Barragan, L.1
Lewis, K.L.2
Firner, S.3
Thiel, V.4
Hugues, S.5
Reith, W.6
Ludewig, B.7
Reizis, B.8
-
31
-
-
77957582392
-
Innate immune activation in primary HIV-1 infection
-
J.J. Chang, and M. Altfeld Innate immune activation in primary HIV-1 infection J. Infect. Dis. 202 Suppl 2 2010 S297 S301
-
(2010)
J. Infect. Dis.
, vol.202
, Issue.SUPPL. 2
-
-
Chang, J.J.1
Altfeld, M.2
-
32
-
-
78649516786
-
HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function
-
M.F. Chevalier, B. Jülg, A. Pyo, M. Flanders, S. Ranasinghe, D.Z. Soghoian, D.S. Kwon, J. Rychert, J. Lian, and M.I. Muller HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function J. Virol. 85 2011 733 741
-
(2011)
J. Virol.
, vol.85
, pp. 733-741
-
-
Chevalier, M.F.1
Jülg, B.2
Pyo, A.3
Flanders, M.4
Ranasinghe, S.5
Soghoian, D.Z.6
Kwon, D.S.7
Rychert, J.8
Lian, J.9
Muller, M.I.10
-
33
-
-
0028032846
-
Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis
-
M. Clerici, A. Sarin, R.L. Coffman, T.A. Wynn, S.P. Blatt, C.W. Hendrix, S.F. Wolf, G.M. Shearer, and P.A. Henkart Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis Proc. Natl. Acad. Sci. USA 91 1994 11811 11815
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11811-11815
-
-
Clerici, M.1
Sarin, A.2
Coffman, R.L.3
Wynn, T.A.4
Blatt, S.P.5
Hendrix, C.W.6
Wolf, S.F.7
Shearer, G.M.8
Henkart, P.A.9
-
34
-
-
79960937640
-
A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection
-
A. Crawford, J.M. Angelosanto, K.L. Nadwodny, S.D. Blackburn, and E.J. Wherry A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection PLoS Pathog. 7 2011 e1002098
-
(2011)
PLoS Pathog.
, vol.7
, pp. 1002098
-
-
Crawford, A.1
Angelosanto, J.M.2
Nadwodny, K.L.3
Blackburn, S.D.4
Wherry, E.J.5
-
35
-
-
79952675131
-
Follicular helper CD4 T cells (TFH)
-
S. Crotty Follicular helper CD4 T cells (TFH) Annu. Rev. Immunol. 29 2011 621 663
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 621-663
-
-
Crotty, S.1
-
36
-
-
84878454838
-
Inadequate T follicular cell help impairs B cell immunity during HIV infection
-
R.A. Cubas, J.C. Mudd, A.L. Savoye, M. Perreau, J. van Grevenynghe, T. Metcalf, E. Connick, A. Meditz, G.J. Freeman, and G. Abesada-Terk Jr. Inadequate T follicular cell help impairs B cell immunity during HIV infection Nat. Med. 19 2013 494 499
-
(2013)
Nat. Med.
, vol.19
, pp. 494-499
-
-
Cubas, R.A.1
Mudd, J.C.2
Savoye, A.L.3
Perreau, M.4
Van Grevenynghe, J.5
Metcalf, T.6
Connick, E.7
Meditz, A.8
Freeman, G.J.9
Abesada-Terk Jr., G.10
-
37
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
C.L. Day, D.E. Kaufmann, P. Kiepiela, J.A. Brown, E.S. Moodley, S. Reddy, E.W. Mackey, J.D. Miller, A.J. Leslie, and C. DePierres PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression Nature 443 2006 350 354
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
Depierres, C.10
-
38
-
-
0142155578
-
Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers
-
C.L. Day, N.P. Seth, M. Lucas, H. Appel, L. Gauthier, G.M. Lauer, G.K. Robbins, Z.M. Szczepiorkowski, D.R. Casson, and R.T. Chung Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers J. Clin. Invest. 112 2003 831 842
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 831-842
-
-
Day, C.L.1
Seth, N.P.2
Lucas, M.3
Appel, H.4
Gauthier, L.5
Lauer, G.M.6
Robbins, G.K.7
Szczepiorkowski, Z.M.8
Casson, D.R.9
Chung, R.T.10
-
39
-
-
84870922385
-
Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory
-
T.A. Doering, A. Crawford, J.M. Angelosanto, M.A. Paley, C.G. Ziegler, and E.J. Wherry Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory Immunity 37 2012 1130 1144
-
(2012)
Immunity
, vol.37
, pp. 1130-1144
-
-
Doering, T.A.1
Crawford, A.2
Angelosanto, J.M.3
Paley, M.A.4
Ziegler, C.G.5
Wherry, E.J.6
-
40
-
-
33750530611
-
Resolution of a chronic viral infection after interleukin-10 receptor blockade
-
M. Ejrnaes, C.M. Filippi, M.M. Martinic, E.M. Ling, L.M. Togher, S. Crotty, and M.G. von Herrath Resolution of a chronic viral infection after interleukin-10 receptor blockade J. Exp. Med. 203 2006 2461 2472
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2461-2472
-
-
Ejrnaes, M.1
Filippi, C.M.2
Martinic, M.M.3
Ling, E.M.4
Togher, L.M.5
Crotty, S.6
Von Herrath, M.G.7
-
41
-
-
67649217469
-
IL-21 is required to control chronic viral infection
-
H. Elsaesser, K. Sauer, and D.G. Brooks IL-21 is required to control chronic viral infection Science 324 2009 1569 1572
-
(2009)
Science
, vol.324
, pp. 1569-1572
-
-
Elsaesser, H.1
Sauer, K.2
Brooks, D.G.3
-
42
-
-
0028839280
-
T helper type 1/T helper type 2 cytokines and T cell death: Preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons
-
J. Estaquier, T. Idziorek, W. Zou, D. Emilie, C.M. Farber, J.M. Bourez, and J.C. Ameisen T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons J. Exp. Med. 182 1995 1759 1767
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1759-1767
-
-
Estaquier, J.1
Idziorek, T.2
Zou, W.3
Emilie, D.4
Farber, C.M.5
Bourez, J.M.6
Ameisen, J.C.7
-
43
-
-
77953535851
-
Opposing positive and negative regulation of T cell activity during viral persistence
-
L.M. Fahey, and D.G. Brooks Opposing positive and negative regulation of T cell activity during viral persistence Curr. Opin. Immunol. 22 2010 348 354
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 348-354
-
-
Fahey, L.M.1
Brooks, D.G.2
-
44
-
-
77953535851
-
Opposing positive and negative regulation of T cell activity during viral persistence
-
L.M. Fahey, and D.G. Brooks Opposing positive and negative regulation of T cell activity during viral persistence Curr. Opin. Immunol. 22 2010 348 354
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 348-354
-
-
Fahey, L.M.1
Brooks, D.G.2
-
45
-
-
79956104027
-
Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells
-
L.M. Fahey, E.B. Wilson, H. Elsaesser, C.D. Fistonich, D.B. McGavern, and D.G. Brooks Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells J. Exp. Med. 208 2011 987 999
-
(2011)
J. Exp. Med.
, vol.208
, pp. 987-999
-
-
Fahey, L.M.1
Wilson, E.B.2
Elsaesser, H.3
Fistonich, C.D.4
McGavern, D.B.5
Brooks, D.G.6
-
46
-
-
0030603841
-
Changing the natural history of HIV disease
-
M.B. Feinberg Changing the natural history of HIV disease Lancet 348 1996 239 246
-
(1996)
Lancet
, vol.348
, pp. 239-246
-
-
Feinberg, M.B.1
-
47
-
-
75149117314
-
Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B
-
693e1-693e4
-
P. Fisicaro, C. Valdatta, M. Massari, E. Loggi, E. Biasini, L. Sacchelli, M.C. Cavallo, E.M. Silini, P. Andreone, and G. Missale Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B Gastroenterology 138 2010 682 693 693e1-693e4
-
(2010)
Gastroenterology
, vol.138
, pp. 682-693
-
-
Fisicaro, P.1
Valdatta, C.2
Massari, M.3
Loggi, E.4
Biasini, E.5
Sacchelli, L.6
Cavallo, M.C.7
Silini, E.M.8
Andreone, P.9
Missale, G.10
-
48
-
-
77950571116
-
Plasmacytoid dendritic cells in HIV infection: Striking a delicate balance
-
P. Fitzgerald-Bocarsly, and E.S. Jacobs Plasmacytoid dendritic cells in HIV infection: striking a delicate balance J. Leukoc. Biol. 87 2010 609 620
-
(2010)
J. Leukoc. Biol.
, vol.87
, pp. 609-620
-
-
Fitzgerald-Bocarsly, P.1
Jacobs, E.S.2
-
49
-
-
77957159060
-
Concomitant type i IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion
-
T. Frenz, Z. Waibler, J. Hofmann, M. Hamdorf, M. Lantermann, B. Reizis, M.G. Tovey, P. Aichele, G. Sutter, and U. Kalinke Concomitant type I IFN receptor-triggering of T cells and of DC is required to promote maximal modified vaccinia virus Ankara-induced T-cell expansion Eur. J. Immunol. 40 2010 2769 2777
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 2769-2777
-
-
Frenz, T.1
Waibler, Z.2
Hofmann, J.3
Hamdorf, M.4
Lantermann, M.5
Reizis, B.6
Tovey, M.G.7
Aichele, P.8
Sutter, G.9
Kalinke, U.10
-
50
-
-
67649234772
-
IL-21R on T cells is critical for sustained functionality and control of chronic viral infection
-
A. Fröhlich, J. Kisielow, I. Schmitz, S. Freigang, A.T. Shamshiev, J. Weber, B.J. Marsland, A. Oxenius, and M. Kopf IL-21R on T cells is critical for sustained functionality and control of chronic viral infection Science 324 2009 1576 1580
-
(2009)
Science
, vol.324
, pp. 1576-1580
-
-
Fröhlich, A.1
Kisielow, J.2
Schmitz, I.3
Freigang, S.4
Shamshiev, A.T.5
Weber, J.6
Marsland, B.J.7
Oxenius, A.8
Kopf, M.9
-
51
-
-
0032832514
-
Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C
-
J.T. Gerlach, H.M. Diepolder, M.C. Jung, N.H. Gruener, W.W. Schraut, R. Zachoval, R. Hoffmann, C.A. Schirren, T. Santantonio, and G.R. Pape Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C Gastroenterology 117 1999 933 941
-
(1999)
Gastroenterology
, vol.117
, pp. 933-941
-
-
Gerlach, J.T.1
Diepolder, H.M.2
Jung, M.C.3
Gruener, N.H.4
Schraut, W.W.5
Zachoval, R.6
Hoffmann, R.7
Schirren, C.A.8
Santantonio, T.9
Pape, G.R.10
-
52
-
-
48749085127
-
Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases
-
M. Gilliet, W. Cao, and Y.J. Liu Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases Nat. Rev. Immunol. 8 2008 594 606
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 594-606
-
-
Gilliet, M.1
Cao, W.2
Liu, Y.J.3
-
53
-
-
0142178211
-
HCV persistence and immune evasion in the absence of memory T cell help
-
A. Grakoui, N.H. Shoukry, D.J. Woollard, J.H. Han, H.L. Hanson, J. Ghrayeb, K.K. Murthy, C.M. Rice, and C.M. Walker HCV persistence and immune evasion in the absence of memory T cell help Science 302 2003 659 662
-
(2003)
Science
, vol.302
, pp. 659-662
-
-
Grakoui, A.1
Shoukry, N.H.2
Woollard, D.J.3
Han, J.H.4
Hanson, H.L.5
Ghrayeb, J.6
Murthy, K.K.7
Rice, C.M.8
Walker, C.M.9
-
55
-
-
79957618772
-
Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine
-
S.G. Hansen, J.C. Ford, M.S. Lewis, A.B. Ventura, C.M. Hughes, L. Coyne-Johnson, N. Whizin, K. Oswald, R. Shoemaker, and T. Swanson Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine Nature 473 2011 523 527
-
(2011)
Nature
, vol.473
, pp. 523-527
-
-
Hansen, S.G.1
Ford, J.C.2
Lewis, M.S.3
Ventura, A.B.4
Hughes, C.M.5
Coyne-Johnson, L.6
Whizin, N.7
Oswald, K.8
Shoemaker, R.9
Swanson, T.10
-
56
-
-
84874280676
-
Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers
-
G.A. Hardy, S. Sieg, B. Rodriguez, D. Anthony, R. Asaad, W. Jiang, J. Mudd, T. Schacker, N.T. Funderburg, and H.A. Pilch-Cooper Interferon-α is the primary plasma type-I IFN in HIV-1 infection and correlates with immune activation and disease markers PLoS ONE 8 2013 e56527
-
(2013)
PLoS ONE
, vol.8
, pp. 56527
-
-
Hardy, G.A.1
Sieg, S.2
Rodriguez, B.3
Anthony, D.4
Asaad, R.5
Jiang, W.6
Mudd, J.7
Schacker, T.8
Funderburg, N.T.9
Pilch-Cooper, H.A.10
-
57
-
-
81055157812
-
Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection
-
J.A. Harker, G.M. Lewis, L. Mack, and E.I. Zuniga Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection Science 334 2011 825 829
-
(2011)
Science
, vol.334
, pp. 825-829
-
-
Harker, J.A.1
Lewis, G.M.2
Mack, L.3
Zuniga, E.I.4
-
58
-
-
33644837684
-
Cutting Edge: The direct action of type i IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection
-
C. Havenar-Daughton, G.A. Kolumam, and K. Murali-Krishna Cutting Edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection J. Immunol. 176 2006 3315 3319
-
(2006)
J. Immunol.
, vol.176
, pp. 3315-3319
-
-
Havenar-Daughton, C.1
Kolumam, G.A.2
Murali-Krishna, K.3
-
59
-
-
79953815120
-
Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression
-
A.R. Hersperger, J.N. Martin, L.Y. Shin, P.M. Sheth, C.M. Kovacs, G.L. Cosma, G. Makedonas, F. Pereyra, B.D. Walker, and R. Kaul Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression Blood 117 2011 3799 3808
-
(2011)
Blood
, vol.117
, pp. 3799-3808
-
-
Hersperger, A.R.1
Martin, J.N.2
Shin, L.Y.3
Sheth, P.M.4
Kovacs, C.M.5
Cosma, G.L.6
Makedonas, G.7
Pereyra, F.8
Walker, B.D.9
Kaul, R.10
-
60
-
-
81555226044
-
The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion
-
K.A. Hofmeyer, H. Jeon, and X. Zang The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion J. Biomed. Biotechnol. 2011 2011 451694
-
(2011)
J. Biomed. Biotechnol.
, vol.2011
, pp. 451694
-
-
Hofmeyer, K.A.1
Jeon, H.2
Zang, X.3
-
61
-
-
0037080190
-
Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III
-
T.M. Holling, N. van der Stoep, E. Quinten, and P.J. van den Elsen Activated human T cells accomplish MHC class II expression through T cell-specific occupation of class II transactivator promoter III J. Immunol. 168 2002 763 770
-
(2002)
J. Immunol.
, vol.168
, pp. 763-770
-
-
Holling, T.M.1
Van Der Stoep, N.2
Quinten, E.3
Van Den Elsen, P.J.4
-
62
-
-
0037384180
-
Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections
-
L. Hunziker, M. Recher, A.J. Macpherson, A. Ciurea, S. Freigang, H. Hengartner, and R.M. Zinkernagel Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections Nat. Immunol. 4 2003 343 349
-
(2003)
Nat. Immunol.
, vol.4
, pp. 343-349
-
-
Hunziker, L.1
Recher, M.2
Macpherson, A.J.3
Ciurea, A.4
Freigang, S.5
Hengartner, H.6
Zinkernagel, R.M.7
-
63
-
-
84855414428
-
Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells
-
S.S. Iyer, J.H. Chatraw, W.G. Tan, E.J. Wherry, T.C. Becker, R. Ahmed, and Z.F. Kapasi Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells J. Immunol. 188 2012 77 84
-
(2012)
J. Immunol.
, vol.188
, pp. 77-84
-
-
Iyer, S.S.1
Chatraw, J.H.2
Tan, W.G.3
Wherry, E.J.4
Becker, T.C.5
Ahmed, R.6
Kapasi, Z.F.7
-
64
-
-
11844264031
-
Cutting edge: MHC class II-restricted killing in vivo during viral infection
-
E.R. Jellison, S.K. Kim, and R.M. Welsh Cutting edge: MHC class II-restricted killing in vivo during viral infection J. Immunol. 174 2005 614 618
-
(2005)
J. Immunol.
, vol.174
, pp. 614-618
-
-
Jellison, E.R.1
Kim, S.K.2
Welsh, R.M.3
-
65
-
-
77957059176
-
Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
-
H.T. Jin, A.C. Anderson, W.G. Tan, E.E. West, S.J. Ha, K. Araki, G.J. Freeman, V.K. Kuchroo, and R. Ahmed Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection Proc. Natl. Acad. Sci. USA 107 2010 14733 14738
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14733-14738
-
-
Jin, H.T.1
Anderson, A.C.2
Tan, W.G.3
West, E.E.4
Ha, S.J.5
Araki, K.6
Freeman, G.J.7
Kuchroo, V.K.8
Ahmed, R.9
-
66
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
R.B. Jones, L.C. Ndhlovu, J.D. Barbour, P.M. Sheth, A.R. Jha, B.R. Long, J.C. Wong, M. Satkunarajah, M. Schweneker, and J.M. Chapman Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection J. Exp. Med. 205 2008 2763 2779
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
Sheth, P.M.4
Jha, A.R.5
Long, B.R.6
Wong, J.C.7
Satkunarajah, M.8
Schweneker, M.9
Chapman, J.M.10
-
67
-
-
52949090785
-
Form follows function: Lymphoid tissue microarchitecture in antimicrobial immune defence
-
T. Junt, E. Scandella, and B. Ludewig Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence Nat. Rev. Immunol. 8 2008 764 775
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 764-775
-
-
Junt, T.1
Scandella, E.2
Ludewig, B.3
-
68
-
-
79959375167
-
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection
-
C. Kao, K.J. Oestreich, M.A. Paley, A. Crawford, J.M. Angelosanto, M.A. Ali, A.M. Intlekofer, J.M. Boss, S.L. Reiner, A.S. Weinmann, and E.J. Wherry Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection Nat. Immunol. 12 2011 663 671
-
(2011)
Nat. Immunol.
, vol.12
, pp. 663-671
-
-
Kao, C.1
Oestreich, K.J.2
Paley, M.A.3
Crawford, A.4
Angelosanto, J.M.5
Ali, M.A.6
Intlekofer, A.M.7
Boss, J.M.8
Reiner, S.L.9
Weinmann, A.S.10
Wherry, E.J.11
-
69
-
-
43049175169
-
Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis
-
D.E. Kaplan, F. Ikeda, Y. Li, N. Nakamoto, S. Ganesan, M.E. Valiga, F.A. Nunes, K. Rajender Reddy, and K.M. Chang Peripheral virus-specific T-cell interleukin-10 responses develop early in acute hepatitis C infection and become dominant in chronic hepatitis J. Hepatol. 48 2008 903 913
-
(2008)
J. Hepatol.
, vol.48
, pp. 903-913
-
-
Kaplan, D.E.1
Ikeda, F.2
Li, Y.3
Nakamoto, N.4
Ganesan, S.5
Valiga, M.E.6
Nunes, F.A.7
Rajender Reddy, K.8
Chang, K.M.9
-
70
-
-
84875759341
-
Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization
-
F. Klein, R. Diskin, J.F. Scheid, C. Gaebler, H. Mouquet, I.S. Georgiev, M. Pancera, T. Zhou, R.B. Incesu, and B.Z. Fu Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization Cell 153 2013 126 138
-
(2013)
Cell
, vol.153
, pp. 126-138
-
-
Klein, F.1
Diskin, R.2
Scheid, J.F.3
Gaebler, C.4
Mouquet, H.5
Georgiev, I.S.6
Pancera, M.7
Zhou, T.8
Incesu, R.B.9
Fu, B.Z.10
-
71
-
-
84875520974
-
A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells
-
K. Ladell, M. Hashimoto, M.C. Iglesias, P.G. Wilmann, J.E. McLaren, S. Gras, T. Chikata, N. Kuse, S. Fastenackels, and E. Gostick A molecular basis for the control of preimmune escape variants by HIV-specific CD8+ T cells Immunity 38 2013 425 436
-
(2013)
Immunity
, vol.38
, pp. 425-436
-
-
Ladell, K.1
Hashimoto, M.2
Iglesias, M.C.3
Wilmann, P.G.4
McLaren, J.E.5
Gras, S.6
Chikata, T.7
Kuse, N.8
Fastenackels, S.9
Gostick, E.10
-
72
-
-
0029899102
-
In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: Effects of interleukin (IL)-12 and anti-IL-10
-
A.L. Landay, M. Clerici, F. Hashemi, H. Kessler, J.A. Berzofsky, and G.M. Shearer In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10 J. Infect. Dis. 173 1996 1085 1091
-
(1996)
J. Infect. Dis.
, vol.173
, pp. 1085-1091
-
-
Landay, A.L.1
Clerici, M.2
Hashemi, F.3
Kessler, H.4
Berzofsky, J.A.5
Shearer, G.M.6
-
73
-
-
34347348127
-
Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification
-
H. Lauterbach, P. Truong, and D.B. McGavern Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification Virol. J. 4 2007 53
-
(2007)
Virol. J.
, vol.4
, pp. 53
-
-
Lauterbach, H.1
Truong, P.2
McGavern, D.B.3
-
74
-
-
38049083122
-
Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
-
M. Law, T. Maruyama, J. Lewis, E. Giang, A.W. Tarr, Z. Stamataki, P. Gastaminza, F.V. Chisari, I.M. Jones, and R.I. Fox Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge Nat. Med. 14 2008 25 27
-
(2008)
Nat. Med.
, vol.14
, pp. 25-27
-
-
Law, M.1
Maruyama, T.2
Lewis, J.3
Giang, E.4
Tarr, A.W.5
Stamataki, Z.6
Gastaminza, P.7
Chisari, F.V.8
Jones, I.M.9
Fox, R.I.10
-
75
-
-
0142092614
-
Cross-priming of CD8+ T cells stimulated by virus-induced type i interferon
-
A. Le Bon, N. Etchart, C. Rossmann, M. Ashton, S. Hou, D. Gewert, P. Borrow, and D.F. Tough Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon Nat. Immunol. 4 2003 1009 1015
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1009-1015
-
-
Le Bon, A.1
Etchart, N.2
Rossmann, C.3
Ashton, M.4
Hou, S.5
Gewert, D.6
Borrow, P.7
Tough, D.F.8
-
76
-
-
59649116097
-
IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment
-
A. Leone, L.J. Picker, and D.L. Sodora IL-2, IL-7 and IL-15 as immuno-modulators during SIV/HIV vaccination and treatment Curr. HIV Res. 7 2009 83 90
-
(2009)
Curr. HIV Res.
, vol.7
, pp. 83-90
-
-
Leone, A.1
Picker, L.J.2
Sodora, D.L.3
-
77
-
-
4644249757
-
Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells
-
M. Lichterfeld, D.E. Kaufmann, X.G. Yu, S.K. Mui, M.M. Addo, M.N. Johnston, D. Cohen, G.K. Robbins, E. Pae, and G. Alter Loss of HIV-1-specific CD8+ T cell proliferation after acute HIV-1 infection and restoration by vaccine-induced HIV-1-specific CD4+ T cells J. Exp. Med. 200 2004 701 712
-
(2004)
J. Exp. Med.
, vol.200
, pp. 701-712
-
-
Lichterfeld, M.1
Kaufmann, D.E.2
Yu, X.G.3
Mui, S.K.4
Addo, M.M.5
Johnston, M.N.6
Cohen, D.7
Robbins, G.K.8
Pae, E.9
Alter, G.10
-
78
-
-
84865997747
-
Expansion of HIV-specific T follicular helper cells in chronic HIV infection
-
M. Lindqvist, J. van Lunzen, D.Z. Soghoian, B.D. Kuhl, S. Ranasinghe, G. Kranias, M.D. Flanders, S. Cutler, N. Yudanin, and M.I. Muller Expansion of HIV-specific T follicular helper cells in chronic HIV infection J. Clin. Invest. 122 2012 3271 3280
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3271-3280
-
-
Lindqvist, M.1
Van Lunzen, J.2
Soghoian, D.Z.3
Kuhl, B.D.4
Ranasinghe, S.5
Kranias, G.6
Flanders, M.D.7
Cutler, S.8
Yudanin, N.9
Muller, M.I.10
-
79
-
-
84862280795
-
Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infection
-
M. Macal, G.M. Lewis, S. Kunz, R. Flavell, J.A. Harker, and E.I. Zúñiga Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infection Cell Host Microbe 11 2012 617 630
-
(2012)
Cell Host Microbe
, vol.11
, pp. 617-630
-
-
Macal, M.1
Lewis, G.M.2
Kunz, S.3
Flavell, R.4
Harker, J.A.5
Zúñiga, E.I.6
-
80
-
-
84855533370
-
Cytotoxic CD4 T cells in antiviral immunity
-
N.B. Marshall, and S.L. Swain Cytotoxic CD4 T cells in antiviral immunity J. Biomed. Biotechnol. 2011 2011 954602
-
(2011)
J. Biomed. Biotechnol.
, vol.2011
, pp. 954602
-
-
Marshall, N.B.1
Swain, S.L.2
-
81
-
-
0027971622
-
CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection
-
M. Matloubian, R.J. Concepcion, and R. Ahmed CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection J. Virol. 68 1994 8056 8063
-
(1994)
J. Virol.
, vol.68
, pp. 8056-8063
-
-
Matloubian, M.1
Concepcion, R.J.2
Ahmed, R.3
-
82
-
-
84879077369
-
Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques
-
D. Mendoza, S.A. Migueles, J.E. Rood, B. Peterson, S. Johnson, N. Doria-Rose, D. Schneider, E. Rakasz, M.T. Trivett, and C.M. Trubey Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques PLoS Pathog. 9 2013 e1003195
-
(2013)
PLoS Pathog.
, vol.9
, pp. 1003195
-
-
Mendoza, D.1
Migueles, S.A.2
Rood, J.E.3
Peterson, B.4
Johnson, S.5
Doria-Rose, N.6
Schneider, D.7
Rakasz, E.8
Trivett, M.T.9
Trubey, C.M.10
-
84
-
-
63149142646
-
B cells in HIV infection and disease
-
S. Moir, and A.S. Fauci B cells in HIV infection and disease Nat. Rev. Immunol. 9 2009 235 245
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 235-245
-
-
Moir, S.1
Fauci, A.S.2
-
85
-
-
70249085585
-
Stromal cell contributions to the homeostasis and functionality of the immune system
-
S.N. Mueller, and R.N. Germain Stromal cell contributions to the homeostasis and functionality of the immune system Nat. Rev. Immunol. 9 2009 618 629
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 618-629
-
-
Mueller, S.N.1
Germain, R.N.2
-
86
-
-
34547782880
-
Regulation of homeostatic chemokine expression and cell trafficking during immune responses
-
S.N. Mueller, K.A. Hosiawa-Meagher, B.T. Konieczny, B.M. Sullivan, M.F. Bachmann, R.M. Locksley, R. Ahmed, and M. Matloubian Regulation of homeostatic chemokine expression and cell trafficking during immune responses Science 317 2007 670 674
-
(2007)
Science
, vol.317
, pp. 670-674
-
-
Mueller, S.N.1
Hosiawa-Meagher, K.A.2
Konieczny, B.T.3
Sullivan, B.M.4
Bachmann, M.F.5
Locksley, R.M.6
Ahmed, R.7
Matloubian, M.8
-
87
-
-
34848852256
-
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection
-
S.N. Mueller, M. Matloubian, D.M. Clemens, A.H. Sharpe, G.J. Freeman, S. Gangappa, C.P. Larsen, and R. Ahmed Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection Proc. Natl. Acad. Sci. USA 104 2007 15430 15435
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 15430-15435
-
-
Mueller, S.N.1
Matloubian, M.2
Clemens, D.M.3
Sharpe, A.H.4
Freeman, G.J.5
Gangappa, S.6
Larsen, C.P.7
Ahmed, R.8
-
88
-
-
77954966127
-
PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice
-
S.N. Mueller, V.K. Vanguri, S.J. Ha, E.E. West, M.E. Keir, J.N. Glickman, A.H. Sharpe, and R. Ahmed PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice J. Clin. Invest. 120 2010 2508 2515
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2508-2515
-
-
Mueller, S.N.1
Vanguri, V.K.2
Ha, S.J.3
West, E.E.4
Keir, M.E.5
Glickman, J.N.6
Sharpe, A.H.7
Ahmed, R.8
-
89
-
-
44649188658
-
Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization
-
1937 e1921-1922
-
N. Nakamoto, D.E. Kaplan, J. Coleclough, Y. Li, M.E. Valiga, M. Kaminski, A. Shaked, K. Olthoff, E. Gostick, and D.A. Price Functional restoration of HCV-specific CD8 T cells by PD-1 blockade is defined by PD-1 expression and compartmentalization Gastroenterology 134 2008 1927 1937 1937 e1921-1922
-
(2008)
Gastroenterology
, vol.134
, pp. 1927-1937
-
-
Nakamoto, N.1
Kaplan, D.E.2
Coleclough, J.3
Li, Y.4
Valiga, M.E.5
Kaminski, M.6
Shaked, A.7
Olthoff, K.8
Gostick, E.9
Price, D.A.10
-
90
-
-
79955386270
-
Immunotherapeutic effects of IL-7 during a chronic viral infection in mice
-
S.G. Nanjappa, E.H. Kim, and M. Suresh Immunotherapeutic effects of IL-7 during a chronic viral infection in mice Blood 117 2011 5123 5132
-
(2011)
Blood
, vol.117
, pp. 5123-5132
-
-
Nanjappa, S.G.1
Kim, E.H.2
Suresh, M.3
-
91
-
-
0029157107
-
Increased mRNA expression of IL-6, IL-10, TNF-alpha, and perforin in blood mononuclear cells in human HIV infection
-
V. Navikas, J. Link, C. Persson, T. Olsson, B. Höjeberg, A. Ljungdahl, H. Link, and B. Wahren Increased mRNA expression of IL-6, IL-10, TNF-alpha, and perforin in blood mononuclear cells in human HIV infection J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 9 1995 484 489
-
(1995)
J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.
, vol.9
, pp. 484-489
-
-
Navikas, V.1
Link, J.2
Persson, C.3
Olsson, T.4
Höjeberg, B.5
Ljungdahl, A.6
Link, H.7
Wahren, B.8
-
92
-
-
84861215802
-
Immortalized clones of fibroblastic reticular cells activate virus-specific T cells during virus infection
-
C.T. Ng, B.P. Nayak, C. Schmedt, and M.B. Oldstone Immortalized clones of fibroblastic reticular cells activate virus-specific T cells during virus infection Proc. Natl. Acad. Sci. USA 109 2012 7823 7828
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 7823-7828
-
-
Ng, C.T.1
Nayak, B.P.2
Schmedt, C.3
Oldstone, M.B.4
-
93
-
-
84865546544
-
Infected CD8α- dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection
-
C.T. Ng, and M.B. Oldstone Infected CD8α- dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection Proc. Natl. Acad. Sci. USA 109 2012 14116 14121
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 14116-14121
-
-
Ng, C.T.1
Oldstone, M.B.2
-
94
-
-
3543104811
-
Beyond help: Direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells
-
P.J. Norris, H.F. Moffett, O.O. Yang, D.E. Kaufmann, M.J. Clark, M.M. Addo, and E.S. Rosenberg Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells J. Virol. 78 2004 8844 8851
-
(2004)
J. Virol.
, vol.78
, pp. 8844-8851
-
-
Norris, P.J.1
Moffett, H.F.2
Yang, O.O.3
Kaufmann, D.E.4
Clark, M.J.5
Addo, M.M.6
Rosenberg, E.S.7
-
95
-
-
29144489019
-
Viral persistence: Parameters, mechanisms and future predictions
-
M.B. Oldstone Viral persistence: parameters, mechanisms and future predictions Virology 344 2006 111 118
-
(2006)
Virology
, vol.344
, pp. 111-118
-
-
Oldstone, M.B.1
-
96
-
-
0023922256
-
Virus-lymphocyte interactions. III. Biologic parameters of a virus variant that fails to generate CTL and establishes persistent infection in immunocompetent hosts
-
M.B. Oldstone, M. Salvato, A. Tishon, and H. Lewicki Virus-lymphocyte interactions. III. Biologic parameters of a virus variant that fails to generate CTL and establishes persistent infection in immunocompetent hosts Virology 164 1988 507 516
-
(1988)
Virology
, vol.164
, pp. 507-516
-
-
Oldstone, M.B.1
Salvato, M.2
Tishon, A.3
Lewicki, H.4
-
97
-
-
0034886599
-
Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells
-
R. Ou, S. Zhou, L. Huang, and D. Moskophidis Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells J. Virol. 75 2001 8407 8423
-
(2001)
J. Virol.
, vol.75
, pp. 8407-8423
-
-
Ou, R.1
Zhou, S.2
Huang, L.3
Moskophidis, D.4
-
98
-
-
79953048089
-
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
-
W. Ouyang, S. Rutz, N.K. Crellin, P.A. Valdez, and S.G. Hymowitz Regulation and functions of the IL-10 family of cytokines in inflammation and disease Annu. Rev. Immunol. 29 2011 71 109
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 71-109
-
-
Ouyang, W.1
Rutz, S.2
Crellin, N.K.3
Valdez, P.A.4
Hymowitz, S.G.5
-
99
-
-
84870230232
-
Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection
-
M.A. Paley, D.C. Kroy, P.M. Odorizzi, J.B. Johnnidis, D.V. Dolfi, B.E. Barnett, E.K. Bikoff, E.J. Robertson, G.M. Lauer, S.L. Reiner, and E.J. Wherry Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection Science 338 2012 1220 1225
-
(2012)
Science
, vol.338
, pp. 1220-1225
-
-
Paley, M.A.1
Kroy, D.C.2
Odorizzi, P.M.3
Johnnidis, J.B.4
Dolfi, D.V.5
Barnett, B.E.6
Bikoff, E.K.7
Robertson, E.J.8
Lauer, G.M.9
Reiner, S.L.10
Wherry, E.J.11
-
100
-
-
84871844273
-
In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice
-
B.E. Palmer, C.P. Neff, J. Lecureux, A. Ehler, M. Dsouza, L. Remling-Mulder, A.J. Korman, A.P. Fontenot, and R. Akkina In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice J. Immunol. 190 2013 211 219
-
(2013)
J. Immunol.
, vol.190
, pp. 211-219
-
-
Palmer, B.E.1
Neff, C.P.2
Lecureux, J.3
Ehler, A.4
Dsouza, M.5
Remling-Mulder, L.6
Korman, A.J.7
Fontenot, A.P.8
Akkina, R.9
-
101
-
-
0242410712
-
Control of effector CD8+ T cell function by the transcription factor Eomesodermin
-
E.L. Pearce, A.C. Mullen, G.A. Martins, C.M. Krawczyk, A.S. Hutchins, V.P. Zediak, M. Banica, C.B. DiCioccio, D.A. Gross, and C.A. Mao Control of effector CD8+ T cell function by the transcription factor Eomesodermin Science 302 2003 1041 1043
-
(2003)
Science
, vol.302
, pp. 1041-1043
-
-
Pearce, E.L.1
Mullen, A.C.2
Martins, G.A.3
Krawczyk, C.M.4
Hutchins, A.S.5
Zediak, V.P.6
Banica, M.7
Dicioccio, C.B.8
Gross, D.A.9
Mao, C.A.10
-
102
-
-
78651225310
-
Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection
-
D. Peppa, L. Micco, A. Javaid, P.T. Kennedy, A. Schurich, C. Dunn, C. Pallant, G. Ellis, P. Khanna, and G. Dusheiko Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection PLoS Pathog. 6 2010 e1001227
-
(2010)
PLoS Pathog.
, vol.6
, pp. 1001227
-
-
Peppa, D.1
Micco, L.2
Javaid, A.3
Kennedy, P.T.4
Schurich, A.5
Dunn, C.6
Pallant, C.7
Ellis, G.8
Khanna, P.9
Dusheiko, G.10
-
103
-
-
33749338938
-
PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
-
C. Petrovas, J.P. Casazza, J.M. Brenchley, D.A. Price, E. Gostick, W.C. Adams, M.L. Precopio, T. Schacker, M. Roederer, D.C. Douek, and R.A. Koup PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection J. Exp. Med. 203 2006 2281 2292
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2281-2292
-
-
Petrovas, C.1
Casazza, J.P.2
Brenchley, J.M.3
Price, D.A.4
Gostick, E.5
Adams, W.C.6
Precopio, M.L.7
Schacker, T.8
Roederer, M.9
Douek, D.C.10
Koup, R.A.11
-
104
-
-
84865395104
-
CD4 T follicular helper cell dynamics during SIV infection
-
C. Petrovas, T. Yamamoto, M.Y. Gerner, K.L. Boswell, K. Wloka, E.C. Smith, D.R. Ambrozak, N.G. Sandler, K.J. Timmer, and X. Sun CD4 T follicular helper cell dynamics during SIV infection J. Clin. Invest. 122 2012 3281 3294
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3281-3294
-
-
Petrovas, C.1
Yamamoto, T.2
Gerner, M.Y.3
Boswell, K.L.4
Wloka, K.5
Smith, E.C.6
Ambrozak, D.R.7
Sandler, N.G.8
Timmer, K.J.9
Sun, X.10
-
105
-
-
79952660523
-
Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner
-
D.L. Popkin, J.R. Teijaro, B.M. Sullivan, S. Urata, S. Rutschmann, J.C. de la Torre, S. Kunz, B. Beutler, and M. Oldstone Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner Cell Host Microbe 9 2011 212 222
-
(2011)
Cell Host Microbe
, vol.9
, pp. 212-222
-
-
Popkin, D.L.1
Teijaro, J.R.2
Sullivan, B.M.3
Urata, S.4
Rutschmann, S.5
De La Torre, J.C.6
Kunz, S.7
Beutler, B.8
Oldstone, M.9
-
106
-
-
2942516628
-
Modulating vaccine responses with dendritic cells and Toll-like receptors
-
B. Pulendran Modulating vaccine responses with dendritic cells and Toll-like receptors Immunol. Rev. 199 2004 227 250
-
(2004)
Immunol. Rev.
, vol.199
, pp. 227-250
-
-
Pulendran, B.1
-
107
-
-
4644219803
-
Deliberate removal of T cell help improves virus-neutralizing antibody production
-
M. Recher, K.S. Lang, L. Hunziker, S. Freigang, B. Eschli, N.L. Harris, A. Navarini, B.M. Senn, K. Fink, and M. Lötscher Deliberate removal of T cell help improves virus-neutralizing antibody production Nat. Immunol. 5 2004 934 942
-
(2004)
Nat. Immunol.
, vol.5
, pp. 934-942
-
-
Recher, M.1
Lang, K.S.2
Hunziker, L.3
Freigang, S.4
Eschli, B.5
Harris, N.L.6
Navarini, A.7
Senn, B.M.8
Fink, K.9
Lötscher, M.10
-
108
-
-
77949361177
-
On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection
-
K. Richter, P. Agnellini, and A. Oxenius On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection Int. Immunol. 22 2010 13 23
-
(2010)
Int. Immunol.
, vol.22
, pp. 13-23
-
-
Richter, K.1
Agnellini, P.2
Oxenius, A.3
-
109
-
-
84855611213
-
Blocking type i interferon production: A new therapeutic option to reduce the HIV-1-induced immune activation
-
M. Ries, K. Pritschet, and B. Schmidt Blocking type I interferon production: a new therapeutic option to reduce the HIV-1-induced immune activation Clin. Dev. Immunol. 2012 2012 534929
-
(2012)
Clin. Dev. Immunol.
, vol.2012
, pp. 534929
-
-
Ries, M.1
Pritschet, K.2
Schmidt, B.3
-
110
-
-
27244444359
-
Blocking of interleukin-10 receptor - A novel approach to stimulate T-helper cell type 1 responses to hepatitis C virus
-
E.I. Rigopoulou, W.G. Abbott, P. Haigh, and N.V. Naoumov Blocking of interleukin-10 receptor - a novel approach to stimulate T-helper cell type 1 responses to hepatitis C virus Clin. Immunol. 117 2005 57 64
-
(2005)
Clin. Immunol.
, vol.117
, pp. 57-64
-
-
Rigopoulou, E.I.1
Abbott, W.G.2
Haigh, P.3
Naoumov, N.V.4
-
111
-
-
0030665257
-
Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia
-
E.S. Rosenberg, J.M. Billingsley, A.M. Caliendo, S.L. Boswell, P.E. Sax, S.A. Kalams, and B.D. Walker Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia Science 278 1997 1447 1450
-
(1997)
Science
, vol.278
, pp. 1447-1450
-
-
Rosenberg, E.S.1
Billingsley, J.M.2
Caliendo, A.M.3
Boswell, S.L.4
Sax, P.E.5
Kalams, S.A.6
Walker, B.D.7
-
112
-
-
84873446224
-
Monitoring cellular immune markers in HIV infection: From activation to exhaustion
-
D. Sauce, C. Elbim, and V. Appay Monitoring cellular immune markers in HIV infection: from activation to exhaustion Curr Opin HIV AIDS 8 2013 125 131
-
(2013)
Curr Opin HIV AIDS
, vol.8
, pp. 125-131
-
-
Sauce, D.1
Elbim, C.2
Appay, V.3
-
113
-
-
84856846467
-
Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence
-
J. Schulze Zur Wiesch, D. Ciuffreda, L. Lewis-Ximenez, V. Kasprowicz, B.E. Nolan, H. Streeck, J. Aneja, L.L. Reyor, T.M. Allen, and A.W. Lohse Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence J. Exp. Med. 209 2012 61 75
-
(2012)
J. Exp. Med.
, vol.209
, pp. 61-75
-
-
Schulze Zur Wiesch, J.1
Ciuffreda, D.2
Lewis-Ximenez, L.3
Kasprowicz, V.4
Nolan, B.E.5
Streeck, H.6
Aneja, J.7
Reyor, L.L.8
Allen, T.M.9
Lohse, A.W.10
-
114
-
-
0034613731
-
Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells
-
N. Sevilla, S. Kunz, A. Holz, H. Lewicki, D. Homann, H. Yamada, K.P. Campbell, J.C. de La Torre, and M.B. Oldstone Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells J. Exp. Med. 192 2000 1249 1260
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1249-1260
-
-
Sevilla, N.1
Kunz, S.2
Holz, A.3
Lewicki, H.4
Homann, D.5
Yamada, H.6
Campbell, K.P.7
De La Torre, J.C.8
Oldstone, M.B.9
-
115
-
-
85047692244
-
Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion
-
N. Sevilla, D.B. McGavern, C. Teng, S. Kunz, and M.B. Oldstone Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion J. Clin. Invest. 113 2004 737 745
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 737-745
-
-
Sevilla, N.1
McGavern, D.B.2
Teng, C.3
Kunz, S.4
Oldstone, M.B.5
-
116
-
-
34247884612
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
-
A.H. Sharpe, E.J. Wherry, R. Ahmed, and G.J. Freeman The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection Nat. Immunol. 8 2007 239 245
-
(2007)
Nat. Immunol.
, vol.8
, pp. 239-245
-
-
Sharpe, A.H.1
Wherry, E.J.2
Ahmed, R.3
Freeman, G.J.4
-
117
-
-
68649096424
-
A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection
-
H. Shin, S.D. Blackburn, A.M. Intlekofer, C. Kao, J.M. Angelosanto, S.L. Reiner, and E.J. Wherry A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection Immunity 31 2009 309 320
-
(2009)
Immunity
, vol.31
, pp. 309-320
-
-
Shin, H.1
Blackburn, S.D.2
Intlekofer, A.M.3
Kao, C.4
Angelosanto, J.M.5
Reiner, S.L.6
Wherry, E.J.7
-
118
-
-
84874280021
-
Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes
-
S. Siegert, and S.A. Luther Positive and negative regulation of T cell responses by fibroblastic reticular cells within paracortical regions of lymph nodes Front. Immunol. 3 2012 285
-
(2012)
Front. Immunol.
, vol.3
, pp. 285
-
-
Siegert, S.1
Luther, S.A.2
-
119
-
-
84857751302
-
HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome
-
D.Z. Soghoian, H. Jessen, M. Flanders, K. Sierra-Davidson, S. Cutler, T. Pertel, S. Ranasinghe, M. Lindqvist, I. Davis, and K. Lane HIV-specific cytolytic CD4 T cell responses during acute HIV infection predict disease outcome Sci. Transl. Med. 4 2012 123ra125
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Soghoian, D.Z.1
Jessen, H.2
Flanders, M.3
Sierra-Davidson, K.4
Cutler, S.5
Pertel, T.6
Ranasinghe, S.7
Lindqvist, M.8
Davis, I.9
Lane, K.10
-
121
-
-
79952582607
-
Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence
-
B.M. Sullivan, S.F. Emonet, M.J. Welch, A.M. Lee, K.P. Campbell, J.C. de la Torre, and M.B. Oldstone Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence Proc. Natl. Acad. Sci. USA 108 2011 2969 2974
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2969-2974
-
-
Sullivan, B.M.1
Emonet, S.F.2
Welch, M.J.3
Lee, A.M.4
Campbell, K.P.5
De La Torre, J.C.6
Oldstone, M.B.7
-
122
-
-
84876311772
-
Persistent LCMV infection is controlled by blockade of type i interferon signaling
-
J.R. Teijaro, C. Ng, A.M. Lee, B.M. Sullivan, K.C. Sheehan, M. Welch, R.D. Schreiber, J.C. de la Torre, and M.B. Oldstone Persistent LCMV infection is controlled by blockade of type I interferon signaling Science 340 2013 207 211
-
(2013)
Science
, vol.340
, pp. 207-211
-
-
Teijaro, J.R.1
Ng, C.2
Lee, A.M.3
Sullivan, B.M.4
Sheehan, K.C.5
Welch, M.6
Schreiber, R.D.7
De La Torre, J.C.8
Oldstone, M.B.9
-
123
-
-
0035914925
-
Determinants of viral clearance and persistence during acute hepatitis C virus infection
-
R. Thimme, D. Oldach, K.M. Chang, C. Steiger, S.C. Ray, and F.V. Chisari Determinants of viral clearance and persistence during acute hepatitis C virus infection J. Exp. Med. 194 2001 1395 1406
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1395-1406
-
-
Thimme, R.1
Oldach, D.2
Chang, K.M.3
Steiger, C.4
Ray, S.C.5
Chisari, F.V.6
-
124
-
-
0027170125
-
Virus-induced immunosuppression. 1. Age at infection relates to a selective or generalized defect
-
A. Tishon, P. Borrow, C. Evans, and M.B. Oldstone Virus-induced immunosuppression. 1. Age at infection relates to a selective or generalized defect Virology 195 1993 397 405
-
(1993)
Virology
, vol.195
, pp. 397-405
-
-
Tishon, A.1
Borrow, P.2
Evans, C.3
Oldstone, M.B.4
-
125
-
-
0028844073
-
An essential role for type 1 interferon-gamma in terminating persistent viral infection
-
A. Tishon, H. Lewicki, G. Rall, M. Von Herrath, and M.B. Oldstone An essential role for type 1 interferon-gamma in terminating persistent viral infection Virology 212 1995 244 250
-
(1995)
Virology
, vol.212
, pp. 244-250
-
-
Tishon, A.1
Lewicki, H.2
Rall, G.3
Von Herrath, M.4
Oldstone, M.B.5
-
126
-
-
67649991445
-
Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population
-
E.A. Torheim, L.C. Ndhlovu, F.O. Pettersen, T.L. Larsen, A.R. Jha, K.M. Torgersen, D. Kvale, D.F. Nixon, K. Taskén, and E.M. Aandahl Interleukin-10-secreting T cells define a suppressive subset within the HIV-1-specific T-cell population Eur. J. Immunol. 39 2009 1280 1287
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 1280-1287
-
-
Torheim, E.A.1
Ndhlovu, L.C.2
Pettersen, F.O.3
Larsen, T.L.4
Jha, A.R.5
Torgersen, K.M.6
Kvale, D.7
Nixon, D.F.8
Taskén, K.9
Aandahl, E.M.10
-
127
-
-
84879122534
-
Early Gag immunodominance of the HIV-specific T-cell response during acute/early infection is associated with higher CD8+ T-cell antiviral activity, and correlates with the preservation of the CD4+ T-cell compartment
-
10.1128/JVI.00865-13 Published online April 24, 2013
-
G. Turk, Y. Ghiglione, J. Falivene, M.E. Socias, N. Laufer, R.S. Coloccini, A.M. Rodriguez, M.J. Ruiz, M.A. Pando, and L.D. Giavedoni Early Gag immunodominance of the HIV-specific T-cell response during acute/early infection is associated with higher CD8+ T-cell antiviral activity, and correlates with the preservation of the CD4+ T-cell compartment J. Virol. 2013 10.1128/JVI.00865-13 Published online April 24, 2013
-
(2013)
J. Virol.
-
-
Turk, G.1
Ghiglione, Y.2
Falivene, J.3
Socias, M.E.4
Laufer, N.5
Coloccini, R.S.6
Rodriguez, A.M.7
Ruiz, M.J.8
Pando, M.A.9
Giavedoni, L.D.10
-
128
-
-
33745876557
-
Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses
-
S. Urbani, B. Amadei, P. Fisicaro, D. Tola, A. Orlandini, L. Sacchelli, C. Mori, G. Missale, and C. Ferrari Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses Hepatology 44 2006 126 139
-
(2006)
Hepatology
, vol.44
, pp. 126-139
-
-
Urbani, S.1
Amadei, B.2
Fisicaro, P.3
Tola, D.4
Orlandini, A.5
Sacchelli, L.6
Mori, C.7
Missale, G.8
Ferrari, C.9
-
129
-
-
39849088117
-
Restoration of HCV-specific T cell functions by PD-1/PD-L1 blockade in HCV infection: Effect of viremia levels and antiviral treatment
-
S. Urbani, B. Amadei, D. Tola, G. Pedrazzi, L. Sacchelli, M.C. Cavallo, A. Orlandini, G. Missale, and C. Ferrari Restoration of HCV-specific T cell functions by PD-1/PD-L1 blockade in HCV infection: effect of viremia levels and antiviral treatment J. Hepatol. 48 2008 548 558
-
(2008)
J. Hepatol.
, vol.48
, pp. 548-558
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
Pedrazzi, G.4
Sacchelli, L.5
Cavallo, M.C.6
Orlandini, A.7
Missale, G.8
Ferrari, C.9
-
130
-
-
84871118297
-
CD8+ T cell-derived IFN-γ prevents infection by a second heterologous virus
-
L. Valentine, R. Potts, and M. Premenko-Lanier CD8+ T cell-derived IFN-γ prevents infection by a second heterologous virus J. Immunol. 189 2012 5841 5848
-
(2012)
J. Immunol.
, vol.189
, pp. 5841-5848
-
-
Valentine, L.1
Potts, R.2
Premenko-Lanier, M.3
-
131
-
-
33749342911
-
Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection
-
V. Vezys, D. Masopust, C.C. Kemball, D.L. Barber, L.A. O'Mara, C.P. Larsen, T.C. Pearson, R. Ahmed, and A.E. Lukacher Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection J. Exp. Med. 203 2006 2263 2269
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2263-2269
-
-
Vezys, V.1
Masopust, D.2
Kemball, C.C.3
Barber, D.L.4
O'Mara, L.A.5
Larsen, C.P.6
Pearson, T.C.7
Ahmed, R.8
Lukacher, A.E.9
-
132
-
-
84869050052
-
HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term
-
B. Vingert, D. Benati, O. Lambotte, P. de Truchis, L. Slama, P. Jeannin, M. Galperin, S. Perez-Patrigeon, F. Boufassa, and W.W. Kwok HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term J. Virol. 86 2012 10661 10674
-
(2012)
J. Virol.
, vol.86
, pp. 10661-10674
-
-
Vingert, B.1
Benati, D.2
Lambotte, O.3
De Truchis, P.4
Slama, L.5
Jeannin, P.6
Galperin, M.7
Perez-Patrigeon, S.8
Boufassa, F.9
Kwok, W.W.10
-
133
-
-
84862294199
-
Timing and magnitude of type i interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection
-
Y. Wang, M. Swiecki, M. Cella, G. Alber, R.D. Schreiber, S. Gilfillan, and M. Colonna Timing and magnitude of type I interferon responses by distinct sensors impact CD8 T cell exhaustion and chronic viral infection Cell Host Microbe 11 2012 631 642
-
(2012)
Cell Host Microbe
, vol.11
, pp. 631-642
-
-
Wang, Y.1
Swiecki, M.2
Cella, M.3
Alber, G.4
Schreiber, R.D.5
Gilfillan, S.6
Colonna, M.7
-
135
-
-
79956077563
-
T cell exhaustion
-
E.J. Wherry T cell exhaustion Nat. Immunol. 12 2011 492 499
-
(2011)
Nat. Immunol.
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
136
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
E.J. Wherry, S.J. Ha, S.M. Kaech, W.N. Haining, S. Sarkar, V. Kalia, S. Subramaniam, J.N. Blattman, D.L. Barber, and R. Ahmed Molecular signature of CD8+ T cell exhaustion during chronic viral infection Immunity 27 2007 670 684
-
(2007)
Immunity
, vol.27
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.J.2
Kaech, S.M.3
Haining, W.N.4
Sarkar, S.5
Kalia, V.6
Subramaniam, S.7
Blattman, J.N.8
Barber, D.L.9
Ahmed, R.10
-
137
-
-
78549270386
-
Translating insights from persistent LCMV infection into anti-HIV immunity
-
E.B. Wilson, and D.G. Brooks Translating insights from persistent LCMV infection into anti-HIV immunity Immunol. Res. 48 2010 3 13
-
(2010)
Immunol. Res.
, vol.48
, pp. 3-13
-
-
Wilson, E.B.1
Brooks, D.G.2
-
138
-
-
79960929116
-
The role of IL-10 in regulating immunity to persistent viral infections
-
E.B. Wilson, and D.G. Brooks The role of IL-10 in regulating immunity to persistent viral infections Curr. Top. Microbiol. Immunol. 350 2011 39 65
-
(2011)
Curr. Top. Microbiol. Immunol.
, vol.350
, pp. 39-65
-
-
Wilson, E.B.1
Brooks, D.G.2
-
139
-
-
84861144540
-
Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection
-
E.B. Wilson, Y. Kidani, H. Elsaesser, J. Barnard, L. Raff, C.L. Karp, S. Bensinger, and D.G. Brooks Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection Cell Host Microbe 11 2012 481 491
-
(2012)
Cell Host Microbe
, vol.11
, pp. 481-491
-
-
Wilson, E.B.1
Kidani, Y.2
Elsaesser, H.3
Barnard, J.4
Raff, L.5
Karp, C.L.6
Bensinger, S.7
Brooks, D.G.8
-
140
-
-
84876299371
-
Blockade of chronic type i interferon signaling to control persistent LCMV infection
-
E.B. Wilson, D.H. Yamada, H. Elsaesser, J. Herskovitz, J. Deng, G. Cheng, B.J. Aronow, C.L. Karp, and D.G. Brooks Blockade of chronic type I interferon signaling to control persistent LCMV infection Science 340 2013 202 207
-
(2013)
Science
, vol.340
, pp. 202-207
-
-
Wilson, E.B.1
Yamada, D.H.2
Elsaesser, H.3
Herskovitz, J.4
Deng, J.5
Cheng, G.6
Aronow, B.J.7
Karp, C.L.8
Brooks, D.G.9
-
141
-
-
33750378183
-
Dendritic-cell interactions with HIV: Infection and viral dissemination
-
L. Wu, and V.N. KewalRamani Dendritic-cell interactions with HIV: infection and viral dissemination Nat. Rev. Immunol. 6 2006 859 868
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 859-868
-
-
Wu, L.1
Kewalramani, V.N.2
-
142
-
-
78649881447
-
Interleukin-21: A multifunctional regulator of immunity to infections
-
J.S. Yi, M.A. Cox, and A.J. Zajac Interleukin-21: a multifunctional regulator of immunity to infections Microbes Infect. 12 2010 1111 1119
-
(2010)
Microbes Infect.
, vol.12
, pp. 1111-1119
-
-
Yi, J.S.1
Cox, M.A.2
Zajac, A.J.3
-
143
-
-
77949357362
-
T-cell exhaustion: Characteristics, causes and conversion
-
J.S. Yi, M.A. Cox, and A.J. Zajac T-cell exhaustion: characteristics, causes and conversion Immunology 129 2010 474 481
-
(2010)
Immunology
, vol.129
, pp. 474-481
-
-
Yi, J.S.1
Cox, M.A.2
Zajac, A.J.3
-
144
-
-
67649203681
-
A vital role for interleukin-21 in the control of a chronic viral infection
-
J.S. Yi, M. Du, and A.J. Zajac A vital role for interleukin-21 in the control of a chronic viral infection Science 324 2009 1572 1576
-
(2009)
Science
, vol.324
, pp. 1572-1576
-
-
Yi, J.S.1
Du, M.2
Zajac, A.J.3
-
145
-
-
84857059757
-
Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells
-
B. Youngblood, E.J. Wherry, and R. Ahmed Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells Curr Opin HIV AIDS 7 2012 50 57
-
(2012)
Curr Opin HIV AIDS
, vol.7
, pp. 50-57
-
-
Youngblood, B.1
Wherry, E.J.2
Ahmed, R.3
-
146
-
-
77956198865
-
HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control
-
F.Y. Yue, C. Lo, A. Sakhdari, E.Y. Lee, C.M. Kovacs, E. Benko, J. Liu, H. Song, R.B. Jones, and P. Sheth HIV-specific IL-21 producing CD4+ T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control J. Immunol. 185 2010 498 506
-
(2010)
J. Immunol.
, vol.185
, pp. 498-506
-
-
Yue, F.Y.1
Lo, C.2
Sakhdari, A.3
Lee, E.Y.4
Kovacs, C.M.5
Benko, E.6
Liu, J.7
Song, H.8
Jones, R.B.9
Sheth, P.10
-
147
-
-
12144291649
-
Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection
-
J.J. Zaunders, W.B. Dyer, B. Wang, M.L. Munier, M. Miranda-Saksena, R. Newton, J. Moore, C.R. Mackay, D.A. Cooper, N.K. Saksena, and A.D. Kelleher Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection Blood 103 2004 2238 2247
-
(2004)
Blood
, vol.103
, pp. 2238-2247
-
-
Zaunders, J.J.1
Dyer, W.B.2
Wang, B.3
Munier, M.L.4
Miranda-Saksena, M.5
Newton, R.6
Moore, J.7
Mackay, C.R.8
Cooper, D.A.9
Saksena, N.K.10
Kelleher, A.D.11
-
148
-
-
84861702017
-
Lymphoid tissue structure and HIV-1 infection: Life or death for T cells
-
M. Zeng, A.T. Haase, and T.W. Schacker Lymphoid tissue structure and HIV-1 infection: life or death for T cells Trends Immunol. 33 2012 306 314
-
(2012)
Trends Immunol.
, vol.33
, pp. 306-314
-
-
Zeng, M.1
Haase, A.T.2
Schacker, T.W.3
-
149
-
-
84865780223
-
Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution
-
M. Zeng, M. Paiardini, J.C. Engram, G.J. Beilman, J.G. Chipman, T.W. Schacker, G. Silvestri, and A.T. Haase Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution Blood 120 2012 1856 1867
-
(2012)
Blood
, vol.120
, pp. 1856-1867
-
-
Zeng, M.1
Paiardini, M.2
Engram, J.C.3
Beilman, G.J.4
Chipman, J.G.5
Schacker, T.W.6
Silvestri, G.7
Haase, A.T.8
|