Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo

Journal of Experimental Medicine

Volumn 208, Issue 12, 2011, Pages 2367-2374

  Swiecki, Melissa ^a   Wang, Yaming ^a   Vermi, Williamd ^b   Gilfillan, Susan ^a   Schreiber, Robert D ^a   Colonna, Marco ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL COUNT; CELL FUNCTION; CONTROLLED STUDY; HEPATITIS B; HEPATITIS C; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOUSE; NONHUMAN; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; APOPTOSIS; DENDRITIC CELLS; FEEDBACK, PHYSIOLOGICAL; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; VIRUS DISEASES;

EID: 84862908654     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20110654     Document Type: Article

References (30)

1. Altfeld, M., L. Fadda, D. Frleta, and N. Bhardwaj. 2011. DCs and NK cells: critical effectors in the immune response to HIV-1. Nat. Rev. Immunol. 11:176-186. http://dx.doi.org/10.1038/nri2935
2. Asselin-Paturel, C., A. Boonstra, M. Dalod, I. Durand, N. Yessaad, C. Dezutter-Dambuyant, A. Vicari, A. O'Garra, C. Biron, F. Brière, and G. Trinchieri. 2001. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2:1144-1150. http://dx.doi.org/10.1038/ni736
3. Asselin-Paturel, C., G. Brizard, K. Chemin, A. Boonstra, A. O'Garra, A. Vicari, and G. Trinchieri. 2005. Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J. Exp. Med. 201:1157-1167. http://dx.doi.org/10.1084/jem.20041930
4. Boasso, A., and G.M. Shearer. 2008. Chronic innate immune activation as a cause of HIV-1 immunopathogenesis. Clin. Immunol. 126:235-242. http://dx.doi.org/10.1016/j.clim.2007.08.015
5. Bouillet, P., D. Metcalf, D.C. Huang, D.M. Tarlinton, T.W. Kay, F. Köntgen, J.M. Adams, and A. Strasser. 1999. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science. 286:1735-1738. http://dx.doi.org/10.1126/science.286.5445.1735
6. Brown, K.N., V. Wijewardana, X. Liu, and S.M. Barratt-Boyes. 2009. Rapid influx and death of plasmacytoid dendritic cells in lymph nodes mediate depletion in acute simian immunodeficiency virus infection. PLoS Pathog. 5:e1000413. http://dx.doi.org/10.1371/journal.ppat.1000413
7. Chen, M., and J. Wang. 2010. Programmed cell death of dendritic cells in immune regulation. Immunol. Rev. 236:11-27. http://dx.doi.org/10.1111/j.1600-065X.2010.00916.x
8. Duan, X.Z., M. Wang, H.W. Li, H. Zhuang, D. Xu, and F.S. Wang. 2004. Decreased frequency and function of circulating plasmocytoid dendritic cells (pDC) in hepatitis B virus infected humans. J. Clin. Immunol. 24:637-646. http://dx.doi.org/10.1007/s10875-004-6249-y
9. Finke, J.S., M. Shodell, K. Shah, F.P. Siegal, and R.M. Steinman. 2004. Dendritic cell numbers in the blood of HIV-1 infected patients before and after changes in antiretroviral therapy. J. Clin. Immunol. 24:647-652. http://dx.doi.org/10.1007/s10875-004-6250-5
10. Fonteneau, J.F., M. Larsson, A.S. Beignon, K. McKenna, I. Dasilva, A. Amara, Y.J. Liu, J.D. Lifson, D.R. Littman, and N. Bhardwaj. 2004. Human immunodeficiency virus type 1 activates plasmacytoid dendritic cells and concomitantly induces the bystander maturation of myeloid dendritic cells. J. Virol. 78:5223-5232. http://dx.doi.org/10.1128/ JVI.78.10.5223-5232.2004
11. Fuertes Marraco, S.A., C.L. Scott, P. Bouillet, A. Ives, S. Masina, D. Vremec, E.S. Jansen, L.A. O'Reilly, P. Schneider, N. Fasel, et al. 2011. Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo. PLoS ONE. 6:e20189. http://dx.doi.org/10.1371/journal.pone.0020189
12. García-Sastre, A., and C.A. Biron. 2006. Type 1 interferons and the virushost relationship: a lesson in détente. Science. 312:879-882. http://dx.doi.org/10.1126/science.1125676
13. Gilliet, M., W. Cao, and Y.J. Liu. 2008. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases. Nat. Rev. Immunol. 8:594-606. http://dx.doi.org/10.1038/nri2358
14. Goutagny, N., C. Vieux, E. Decullier, B. Ligeoix, A. Epstein, C. Trepo, P. Couzigou, G. Inchauspe, and C. Bain. 2004. Quantification and functional analysis of plasmacytoid dendritic cells in patients with chronic hepatitis C virus infection. J. Infect. Dis. 189:1646-1655. http://dx.doi.org/10.1086/383248
15. Kadowaki, N., S. Antonenko, J.Y. Lau, and Y.J. Liu. 2000. Natural interferon α/β-producing cells link innate and adaptive immunity. J. Exp. Med. 192:219-226. http://dx.doi.org/10.1084/jem.192.2.219
16. Kanto, T., M. Inoue, H. Miyatake, A. Sato, M. Sakakibara, T. Yakushijin, C. Oki, I. Itose, N. Hiramatsu, T. Takehara, et al. 2004. Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection. J. Infect. Dis. 190:1919-1926. http://dx.doi.org/10.1086/425425
17. Kaufmann, T., L. Tai, P.G. Ekert, D.C. Huang, F. Norris, R.K. Lindemann, R.W. Johnstone, V.M. Dixit, and A. Strasser. 2007. The BH3- only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest. Cell. 129:423-433. http://dx.doi.org/10.1016/j.cell.2007.03.017
18. Krug, A., G.D. Luker, W. Barchet, D.A. Leib, S. Akira, and M. Colonna. 2004. Herpes simplex virus type 1 activates murine natural interferonproducing cells through toll-like receptor 9. Blood. 103:1433-1437. http://dx.doi.org/10.1182/blood-2003-08-2674
19. Lee, L.N., S. Burke, M. Montoya, and P. Borrow. 2009. Multiple mechanisms contribute to impairment of type 1 interferon production during chronic lymphocytic choriomeningitis virus infection of mice. J. Immunol. 182:7178-7189. http://dx.doi.org/10.4049/jimmunol.0802526
20. 4+ Th1 immunity with poly IC as adjuvant. J. Exp. Med. 206:1589-1602. http://dx.doi.org/10.1084/jem.20090247
21. Malleret, B., B. Manéglier, I. Karlsson, P. Lebon, M. Nascimbeni, L. Perié, P. Brochard, B. Delache, J. Calvo, T. Andrieu, et al. 2008. Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression. Blood. 112:4598-4608. http://dx.doi.org/10.1182/blood-2008-06-162651
22. Mattei, F., L. Bracci, D.F. Tough, F. Belardelli, and G. Schiavoni. 2009. Type I IFN regulate DC turnover in vivo. Eur. J. Immunol. 39:1807-1818. http://dx.doi.org/10.1002/eji.200939233
23. Nopora, A., and T. Brocker. 2002. Bcl-2 controls dendritic cell longevity in vivo. J. Immunol. 169:3006-3014.
24. Swiecki, M., S. Gilfillan, W. Vermi, Y. Wang, and M. Colonna. 2010. Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual. Immunity. 33:955-966. http://dx.doi.org/10.1016/j.immuni.2010.11.020
25. Trinchieri, G. 2010. Type I interferon: friend or foe? J. Exp. Med. 207:2053-2063. http://dx.doi.org/10.1084/jem.20101664
26. Villadangos, J.A., and L. Young. 2008. Antigen-presentation properties of plasmacytoid dendritic cells. Immunity. 29:352-361. http://dx.doi.org/10.1016/j.immuni.2008.09.002
27. Watarai, H., E. Sekine, S. Inoue, R. Nakagawa, T. Kaisho, and M. Taniguchi. 2008. PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon. Proc. Natl. Acad. Sci. USA. 105:2993-2998. http://dx.doi.org/10.1073/pnas.0710351105
28. Yen, J.H., and D. Ganea. 2009. Interferon beta induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation. Blood. 114:1344-1354. http://dx.doi.org/10.1182/blood-2008-12-196592
29. Youle, R.J., and A. Strasser. 2008. The BCL-2 protein family: opposing activities that mediate cell death. Nat. Rev. Mol. Cell Biol. 9:47-59. http://dx.doi.org/10.1038/nrm2308
30. Zuniga, E.I., L.Y. Liou, L. Mack, M. Mendoza, and M.B. Oldstone. 2008. Persistent virus infection inhibits type I interferon production by plasmacytoid dendritic cells to facilitate opportunistic infections. Cell Host Microbe. 4:374-386. http://dx.doi.org/10.1016/j.chom.2008.08.016