Gαq signalling: The new and the old

Cellular Signalling

Volumn 26, Issue 5, 2014, Pages 833-848

  Sánchez Fernández, Guzmán ^a,b   Cabezudo, Sofía ^a,b   García Hoz, Carlota ^a,b   Benincá, Cristiane ^c   Aragay, Anna M ^d   Mayor, Federico ^a,b   Ribas, Catalina ^a,b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas   (Spain)

^c CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^d INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

Author keywords

G protein; G protein coupled receptors; Gq; Interactome; Signalling pathways

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE 5; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C BETA; PROTEIN KINASE B; PROTEIN KINASE C ZETA; PROTEIN P63; REGULATOR PROTEIN; RGS PROTEIN; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL M8;

CALCIUM SIGNALING; CELL MEMBRANE; CRYSTAL STRUCTURE; CYTOLOGY; CYTOSKELETON; DEVELOPMENTAL BIOLOGY; DISEASE COURSE; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; HEART DISEASE; HUMAN; NONHUMAN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; TRANSCRIPTION INITIATION;

G PROTEIN; G-PROTEIN COUPLED RECEPTORS; GQ; INTERACTOME; SIGNALLING PATHWAYS;

CELLULAR MICROENVIRONMENT; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MAP KINASE KINASE 5; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOLIPASE C BETA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84893635948     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.01.010     Document Type: Review

References (231)

1. Pierce K.L., Premont R.T., Lefkowitz R.J. Nat. Rev. Mol. Cell Biol. 2002, 3:639-650.
2. Hepler J.R., Gilman A.G. Trends Biochem. Sci. 1992, 17:383-387.
3. Standfuss J., Edwards P.C., D'Antona A., Fransen M., Xie G., Oprian D.D., et al. Nature 2011, 471:656-660.
4. Rasmussen S.G.F., DeVree B.T., Zou Y., Kruse A.C., Chung K.Y., Kobilka T.S., et al. Nature 2011, 477:549-555.
5. Wilden U. Biochemistry 1995, 34:1446-1454.
6. Ribas C., Penela P., Murga C., Salcedo A., García-Hoz C., Jurado-Pueyo M., et al. Biochim. Biophys. Acta 2007, 1768:913-922.
7. DeWire S.M., Ahn S., Lefkowitz R.J., Shenoy S.K. Annu. Rev. Physiol. 2007, 69:483-510.
8. Milligan G., Kostenis E. Br. J. Pharmacol. 2006, 147:S46-S55. (Suppl.).
9. Simon M., Strathmann M., Gautam N. Science 1991, 252:802-808. (80-.).
10. Oka Y., Saraiva L.R., Kwan Y.Y., Korsching S.I. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:1484-1489.
11. Hubbard K.B., Hepler J.R. Cell. Signal. 2006, 18:135-150.
12. Rhee S. Annu. Rev. Biochem. 2001, 70:281-312.
13. Golebiewska U., Scarlata S. Biophys. J. 2008, 95:2575-2582.
14. Lutz S., Shankaranarayanan A., Coco C., Ridilla M., Nance M.R., Vettel C., et al. Science 2007, 318:1923-1927.
15. Lutz S., Freichel-Blomquist A., Yang Y., Rümenapp U., Jakobs K.H., Schmidt M., et al. J. Biol. Chem. 2005, 280:11134-11139.
16. Vaqué J.P., Dorsam R.T., Feng X., Iglesias-Bartolome R., Forsthoefel D.J., Chen Q., et al. Mol. Cell 2013, 49:94-108.
17. García-Hoz C., Sánchez-Fernández G., Díaz-Meco M.T., Moscat J., Mayor F., Ribas C. J. Biol. Chem. 2010, 285:13480-13489.
18. García-Hoz C., Sánchez-Fernández G., García-Escudero R., Fernández-Velasco M., Palacios-García J., Ruiz-Meana M., et al. J. Biol. Chem. 2012, 287:7792-7802.
19. Oldham W.M., Hamm H.E. Nat. Rev. Mol. Cell Biol. 2008, 9:60-71.
20. Mizuno N., Itoh H. Neurosignals 2009, 17:42-54.
21. Echeverria V., Hinrichs M.V., Torrejon M., Ropero S., Martinez J., Toro M.J., et al. J. Cell. Biochem. 2000, 76:368-375.
22. Oldham W.M., Hamm H.E. Q. Rev. Biophys. 2006, 39:117-166.
23. Linder M.E., Middleton P., Hepler J.R., Taussig R., Gilman a G., Mumby S.M. Proc. Natl. Acad. Sci. U. S. A. 1993, 90:3675-3679.
24. Stanislaus D., Janovick J.A., Brothers S., Conn P.M. Mol. Endocrinol. 1997, 11:738-746.
25. Wedegaertner P.B., Chu D.H., Wilson P.T., Levis M.J., Bourne H.R. J. Biol. Chem. 1993, 268:25001-25008.
26. Wise A., Carr I.C., Groarke D.A., Milligan G. FEBS Lett. 1997, 419:141-146.
27. Crouthamel M., Thiyagarajan M.M., Evanko D.S., Wedegaertner P.B. Cell. Signal. 2008, 20:1900-1910.
28. Crouthamel M., Abankwa D., Zhang L. Mol. Pharmacol. 2010, 78:767-777.
29. Sprang S.R., Chen Z., Du X. Adv. Protein Chem. 2007, 74:1-65.
30. Carman C.V., Parent J.L., Day P.W., Pronin a N., Sternweis P.M., Wedegaertner P.B., et al. J. Biol. Chem. 1999, 274:34483-34492.
31. Waldo G.L., Ricks T.K., Hicks S.N., Cheever M.L., Kawano T., Tsuboi K., et al. Science 2010, 330:974-980.
32. Tesmer V.M., Kawano T., Shankaranarayanan A., Kozasa T., Tesmer J.J.G. Science 2005, 310:1686-1690.
33. Ross E.M. Sci. Signal. 2011, 4:e5.
34. Shankaranarayanan A., Thal D.M., Tesmer V.M., Roman D.L., Neubig R.R., Kozasa T., et al. J. Biol. Chem. 2008, 283:34923-34934.
35. Lyon A.M., Tesmer V.M., Dhamsania V.D., Thal D.M., Gutierrez J., Chowdhury S., et al. Nat. Struct. Mol. Biol. 2011, 18:999-1005.
36. Shankaranarayanan A., Boguth C.A., Lutz S., Vettel C., Uhlemann F., Aittaleb M., et al. Cell. Signal. 2010, 22:1114-1123.
37. Rossman K.L., Der C.J., Sondek J. Nat. Rev. Mol. Cell Biol. 2005, 6:167-180.
38. Welch H.C.E., Coadwell W.J., Ellson C.D., Ferguson G.J., Andrews S.R., Erdjument-Bromage H., et al. Cell 2002, 108:809-821.
39. Tesmer J.J., Berman D.M., Gilman a G., Sprang S.R. Cell 1997, 89:251-261.
40. Fan G., Ballou L.M., Lin R.Z. J. Biol. Chem. 2003, 278:52432-52436.
41. Drin G., Scarlata S. Cell. Signal. 2007, 19:1383-1392.
42. Harden T.K., Waldo G.L., Hicks S.N., Sondek J. Chem. Rev. 2011, 111:6120-6129.
43. Adjobo-Hermans M.J.W., Goedhart J., van Weeren L., Nijmeijer S., Manders E.M.M., Offermanns S., et al. BMC Biol. 2011, 9:32.
44. Liu S., Carrillo J.J., Pediani J.D., Milligan G. J. Biol. Chem. 2002, 277:25707-25714.
45. Umemori H., Inoue T., Kume S., Sekiyama N., Nagao M., Itoh H., et al. Science 1997, 276:1878-1881.
46. Kolch W., Heidecker G., Kochs G., Hummel R., Vahidi H., Mischak H., et al. Nature 1993, 364:249-252.
47. Faure M., Voyno-Yasenetskaya T.A., Bourne H.R. J. Biol. Chem. 1994, 269:7851-7854.
48. Dikic I., Tokiwa G., Lev S., Courtneidge S.A., Schlessinger J. Nature 1996, 383:547-550.
49. Minamino T., Yujiri T., Terada N., Taffet G.E., Michael L.H., Johnson G.L., et al. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:3866-3871.
50. Goldsmith Z.G., Dhanasekaran D.N. Oncogene 2007, 26:3122-3142.
51. Etienne-Manneville S., Hall A. Nature 2002, 420:629-635.
52. Ridley A.J. Trends Cell Biol. 2006, 16:522-529.
53. Bos J.L., Rehmann H., Wittinghofer A. Cell 2007, 129:865-877.
54. Vogt S., Grosse R., Schultz G., Offermanns S. J. Biol. Chem. 2003, 278:28743-28749.
55. Booden M., Siderovski D., C.JD Mol. Cell. Biol. 2002, 22:4053-4061.
56. Chikumi H., Vázquez-Prado J., Servitja J.-M., Miyazaki H., Gutkind J.S. J. Biol. Chem. 2002, 277:27130-27134.
57. Fukuhara S., Marinissen M.J., Chiariello M., Gutkind J.S. J. Biol. Chem. 2000, 275:21730-21736.
58. Pfreimer M., Vatter P., Langer T., Wieland T., Gierschik P., Moepps B. Cell. Signal. 2012, 24:652-663.
59. Rojas R.J., Yohe M.E., Gershburg S., Kawano T., Kozasa T., Sondek J. J. Biol. Chem. 2007, 282:29201-29210.
60. Williams S.L., Lutz S., Charlie N.K., Vettel C., Ailion M., Coco C., et al. Genes Dev. 2007, 21:2731-2746.
61. Sagi S.A., Seasholtz T.M., Kobiashvili M., Wilson B.A., Toksoz D., Brown J.H. J. Biol. Chem. 2001, 276:15445-15452.
62. Lutz S., Freichel-Blomquist A., Rümenapp U., Schmidt M., Jakobs K.H., Wieland T. Naunyn. Schmiedebergs. Arch. Pharmacol. 2004, 369:540-546.
63. Goedhart J., van Unen J., Adjobo-Hermans M.J.W., Gadella T.W.J. Sci. Rep. 2013, 3:2284.
64. Swenson-Fields K.I., Sandquist J.C., Rossol-Allison J., Blat I.C., Wennerberg K., Burridge K., et al. Mol. Cell 2008, 32:43-56.
65. Tang X., Jin R., Qu G., Wang X., Li Z., Yuan Z., et al. Cancer Res. 2013, 73:6206-6218.
66. Ballou L.M., Cross M.E., Huang S., McReynolds E.M., Zhang B.X., Lin R.Z. J. Biol. Chem. 2000, 275:4803-4809.
67. Ballou L.M., Lin H.-Y., Fan G., Jiang Y.-P., Lin R.Z. J. Biol. Chem. 2003, 278:23472-23479.
68. Ballou L.M., Chattopadhyay M., Li Y., Scarlata S., Lin R.Z. Biochem. J. 2006, 394:557-562.
69. Xie P., Browning D.D., Hay N., Mackman N., Ye R.D. J. Biol. Chem. 2000, 275:24907-24914.
70. Imamura T., Vollenweider P., Egawa K., Clodi M., Ishibashi K., Nakashima N., et al. Mol. Cell. Biol. 1999, 19:6765-6774.
71. Dhanasekaran N., Tsim S.T., Dermott J.M., Onesime D. Oncogene 1998, 17:1383-1394.
72. Klasen K., Hollatz D., Zielke S., Gisselmann G., Hatt H., Wetzel C.H. Pflugers Arch. 2012, 463:779-797.
73. Zhang X., Mak S., Li L., Parra A., Denlinger B., Belmonte C., et al. Nat. Cell Biol. 2012, 14:851-858.
74. Li L., Zhang X. Channels (Austin) 2013, 7:1-4.
75. Hartmann J., Blum R., Kovalchuk Y., Adelsberger H., Kuner R., Durand G.M., et al. J. Neurosci. 2004, 24:5119-5130.
76. Offermanns S., Zhao L.P., Gohla A., Sarosi I., Simon M.I., Wilkie T.M. EMBO J. 1998, 17:4304-4312.
77. Offermanns S., Toombs C.F., Hu Y.H., Simon M.I. Nature 1997, 389:183-186.
78. Krause M., Offermanns S., Stocker M., Pedarzani P. J. Neurosci. 2002, 22:666-673.
79. Zywietz a, Gohla a, Schmelz M., Schultz G., Offermanns S. J. Biol. Chem. 2001, 276:3840-3845.
80. Orth J.H.C., Lang S., Aktories K. J. Biol. Chem. 2004, 279:34150-34155.
81. Orth J.H.C., Lang S., Preuss I., Milligan G., Aktories K. Cell. Signal. 2007, 19:2174-2182.
82. Orth J.H.C., Preuss I., Fester I., Schlosser A., Wilson B.A., Aktories K. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:7179-7184.
83. Orth J.H.C., Fester I., Siegert P., Weise M., Lanner U., Kamitani S., et al. FASEB J. 2013, 27:832-842.
84. Turjanski A.G., Vaqué J.P., Gutkind J.S. Oncogene 2007, 26:3240-3253.
85. Widmann C., Gibson S., Jarpe M.B., Johnson G.L. Physiol. Rev. 1999, 79:143-180.
86. Berts a, Zhong H., Minneman K.P. Mol. Pharmacol. 1999, 55:296-303.
87. Coso O.A., Chiariello M., Kalinec G., Kyriakis J.M., Woodgett J., Gutkind J.S. J. Biol. Chem. 1995, 270:5620-5624.
88. Heasley L., Storey B. Mol. Cell. Biol. 1996, 16:648.
89. Seo B., Choy E.W., Maudsley S., Miller W.E., Wilson B.A., Luttrell L.M. J. Biol. Chem. 2000, 275:2239-2245.
90. Peavy R.D., Chang M.S., Sanders-Bush E., Conn P.J. J. Neurosci. 2001, 21:9619-9628.
91. Venkatakrishnan G., Exton J.H. J. Biol. Chem. 1996, 271:5066-5072.
92. Foley J.F. Sci. Signal. 2010, 3.
93. Luttrell L.M., Roudabush F.L., Choy E.W., Miller W.E., Field M.E., Pierce K.L., et al. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:2449-2454.
94. McDonald P.H., Chow C.W., Miller W.E., Laporte S.A., Field M.E., Lin F.T., et al. Science 2000, 290:1574-1577.
95. Song X., Coffa S., Fu H., Gurevich V.V. J. Biol. Chem. 2009, 284:685-695.
96. Sánchez-Fernández G., Cabezudo S., García-Hoz C., Tobin A.B., Mayor F., Ribas C. PLoS One 2014, 8:e84174.
97. Bence K., Ma W., Kozasa T., Huang X.Y. Nature 1997, 389:296-299.
98. Ma Y.C., Huang X.Y. Proc. Natl. Acad. Sci. 1998, 95:12197.
99. Lindvall J.M., Blomberg K.E.M., Väliaho J., Vargas L., Heinonen J.E., Berglöf A., et al. Immunol. Rev. 2005, 203:200-215.
100. Mohamed A.J., Yu L., Bäckesjö C.-M., Vargas L., Faryal R., Aints A., et al. Immunol. Rev. 2009, 228:58-73.
101. Watson N., Linder M.E., Druey K.M., Kehrl J.H., Blumer K.J. Nature 1996, 383:172-175.
102. Bansal G., Druey K.M., Xie Z. Pharmacol. Ther. 2007, 116:473-495.
103. Xu X., Zeng W., Popov S., Berman D.M., Davignon I., Yu K., et al. J. Biol. Chem. 1999, 274:3549-3556.
104. Penela P., Murga C., Ribas C., Tutor A.S., Peregrín S., Mayor F. Cardiovasc. Res. 2006, 69:46-56.
105. Day P.W., Carman C.V., Sterne-Marr R., Benovic J.L., Wedegaertner P.B. Biochemistry 2003, 42:9176-9184.
106. Sallese M., Mariggiò S., D'Urbano E., Iacovelli L., De Blasi a Mol. Pharmacol. 2000, 57:826-831.
107. Ferguson S.S.G. Trends Pharmacol. Sci. 2007, 28:173-179.
108. Usui I., Imamura T., Satoh H., Huang J., Babendure J.L., Hupfeld C.J., et al. EMBO J. 2004, 23:2821-2829.
109. Garcia-Guerra L., Nieto-Vazquez I., Vila-Bedmar R., Jurado-Pueyo M., Zalba G., Díez J., et al. Diabetes 2010, 59:2407-2417.
110. Mariggiò S., García-Hoz C., Sarnago S., De Blasi A., Mayor F., Ribas C. Cell. Signal. 2006, 18:2004-2012.
111. Carman C.V., Lisanti M.P., Benovic J.L. J. Biol. Chem. 1999, 274:8858-8864.
112. Sengupta P., Philip F., Scarlata S. J. Cell Sci. 2008, 121:1363-1372.
113. Malhotra R., D'Souza K.M., Staron M.L., Birukov K.G., Bodi I., Akhter S.a J. Biol. Chem. 2010, 285:13748-13760.
114. Cartier A., Parent A., Labrecque P., Laroche G., Parent J.-L. J. Cell Sci. 2011, 124:3292-3304.
115. Little K.D., Hemler M.E., Stipp C.S. Dynamic Regulation of a GPCR-Tetraspanin-G Protein Complex on Intact Cells: Central Role of CD81 in Facilitating GPR56-Galphaq/11 Association 2004, 15:2375-2387.
116. Rochdi M.D., Watier V., La Madeleine C., Nakata H., Kozasa T., Parent J.-L. J. Biol. Chem. 2002, 277:40751-40759.
117. Rochdi M.D., Parent J.-L. J. Biol. Chem. 2003, 278:17827-17837.
118. Blumer J.B., Cismowski M.J., Sato M., Lanier S.M. Trends Pharmacol. Sci. 2005, 26:470-476.
119. Miller K.G., Emerson M.D., McManus J.R., Rand J.B. Neuron 2000, 27:289-299.
120. Tall G.G., Krumins A.M., Gilman A.G. J. Biol. Chem. 2003, 278:8356-8362.
121. Chan P., Thomas C.J., Sprang S.R., Tall G.G. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:3794-3799.
122. Tall G.G. J. Recept. Signal Transduct. Res. 2013, 33:139-143.
123. Nishimura A., Okamoto M., Sugawara Y., Mizuno N., Yamauchi J., Itoh H. Genes Cells 2006, 11:487-498.
124. Wang L., Guo D., Xing B., Zhang J.J., Shu H.-B., Guo L., et al. J. Biol. Chem. 2011, 286:31055-31061.
125. Gabay M., Pinter M.E., Wright F.A., Chan P., Murphy A.J., Valenzuela D.M., et al. Sci. Signal. 2011, 4:ra79.
126. Chishiki K., Kamakura S., Yuzawa S., Hayase J., Sumimoto H. Biochem. Biophys. Res. Commun. 2013, 435:414-419.
127. Hinrichs M.V., Torrejón M., Montecino M., Olate J. J. Cell. Biochem. 2012, 113:2797-2805.
128. Irannejad R., Tomshine J.C., Tomshine J.R., Chevalier M., Mahoney J.P., Steyaert J., et al. Nature 2013, 495:534-538.
129. Schappi J.M., Krbanjevic A., Rasenick M.M. Biochim. Biophys. Acta 2013, 1838:674-681.
130. Wang N., Yan K., Rasenick M.M. J. Biol. Chem. 1990, 265:1239-1242.
131. Dave R.H., Saengsawang W., Yu J.-Z., Donati R., Rasenick M.M. Neurosignals 2009, 17:100-108.
132. Sarma T., Voyno-Yasenetskaya T., Hope T.J., Rasenick M.M. FASEB J. 2003, 17:848-859.
133. Yu J.-Z., Rasenick M.M. Mol. Pharmacol. 2002, 61:352-359.
134. Ciruela F., McIlhinney R.A. J. Neurochem. 2001, 76:750-757.
135. Popova J.S., Rasenick M.M. J. Biol. Chem. 2003, 278:34299-34308.
136. Ibarrondo J., Joubert D., Dufour M.N., Cohen-Solal A., Homburger V., Jard S., et al. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:8413-8417.
137. Simons K., Toomre D. Nat. Rev. Mol. Cell Biol. 2000, 1:31-39.
138. Head B.P., Patel H.H., Insel P.A. Biochim. Biophys. Acta 2013, 1838:532-545.
139. Oh P., Schnitzer J.E. Mol. Biol. Cell 2001, 12:685-698.
140. Qiu Y., Wang Y., Law P., Chen H., Loh H.H. Mol. Pharmacol. 2011, 210-218.
141. Bhatnagar A., Sheffler D.J., Kroeze W.K., Compton-Toth B., Roth B.L. J. Biol. Chem. 2004, 279:34614-34623.
142. Takahashi-Iwanaga H., Iwanaga T. J. Comp. Neurol. 2012, 520:2053-2066.
143. Bhattacharya S., Mahavadi S., Al-Shboul O., Rajagopal S., Grider J.R., Murthy K.S. Am. J. Physiol. Cell Physiol. 2013, 305:C334-C347.
144. Guo Y., Golebiewska U., Scarlata S. Biophys. J. 2011, 100:1599-1607.
145. Calizo R.C., Scarlata S. Biochemistry 2012, 51:9513-9523.
146. Pesanová Z., Novotný J., Cerný J., Milligan G., Svoboda P. FEBS Lett. 1999, 464:35-40.
147. Solis G.P., Hülsbusch N., Radon Y., Katanaev V.L., Plattner H., Stuermer C.A.O. Mol. Biol. Cell 2013, 24:2689-2702.
148. Sugawara Y., Nishii H., Takahashi T., Yamauchi J., Mizuno N., Tago K., et al. Cell. Signal. 2007, 19:1301-1308.
149. Ando K., Obara Y., Sugama J., Kotani A., Koike N., Ohkubo S., et al. J. Pharmacol. Exp. Ther. 2010, 334:809-819.
150. Yajima T., Inoue R., Yajima M., Tsuruta T., Karaki S., Hira T., et al. Acta Physiol. (Oxf.) 2011, 203:381-389.
151. Piskunov a, Rochette-Egly C. Oncogene 2011, 1-13.
152. Hewavitharana T., Wedegaertner P.B. Cell. Signal. 2011, 24:25-34.
153. Kuyznierewicz I., Thomson M. Cell Biol. Int. 2002, 26:99-108.
154. Lyssand J.S., Bajjalieh S.M. FEBS Lett. 2007, 581:5765-5768.
155. Andreeva A.V., Kutuzov M.A., Voyno-Yasenetskaya T.A. FASEB J. 2008, 22:2821-2831.
156. Ratnaparkhi A. J. Cell Sci. 2013, 126:5369-5376.
157. Zhang J., Liu W., Liu J., Xiao W., Liu L., Jiang C., et al. Nat. Commun. 2010, 1:101.
158. Benincá C., Planagumà J., de Freitas Shuck A., Acín-Perez R., Muñoz J., Mateus de Almeida M., et al. A new non-canonical pathway of Gq protein regulating mitochondrial dynamics and bioenergetics 2014, (in this volume).
159. Wettschureck N., Offermanns S. Physiol. Rev. 2005, 1159-1204.
160. Keys J.R., Greene E.A., Koch W.J., Eckhart A.D. Hypertension 2002, 40:660-666.
161. Caulfield M.P. Pharmacol. Ther. 1993, 58:319-379.
162. Johnson G.J., Leis L.A., Dunlop P.C. Biochem. J. 1996, 318(Pt 3):1023-1031.
163. Liu Y., Gan L., Shi G. Am. J. Immunol. 2012, 8:154-165.
164. Imamura T., Vollenweider P. Mol. Cell. Biol. 1999, 19:6765.
165. Hua Li J., Jain S., McMillin S.M., Cui Y., Gautam D., Sakamoto W., et al. Endocrinology 2013, 154:3539-3551.
166. Miyata M., Finch E.A., Khiroug L., Hashimoto K., Hayasaka S., Oda S.I., et al. Neuron 2000, 28:233-244.
167. Kan Z., Jaiswal B.S., Stinson J., Janakiraman V., Bhatt D., Stern H.M., et al. Nature 2010, 466:869-873.
168. Van Raamsdonk C.D., Griewank K., Crosby M.B., Garrido M.C., Vemula S., Wiesner T., et al. N. Engl. J. Med. 2010, 363:2191-2199.
169. Van Raamsdonk C., Bezrookove V., Green G. Nature 2008, 457.
170. O'Hayre M., Vázquez-Prado J., Kufareva I., Stawiski E.W., Handel T.M., Seshagiri S., et al. Nat. Rev. Cancer 2013, 13:412-424.
171. Ishizuka T., Goshima H., Ozawa A., Watanabe Y. Eur. J. Pharmacol. 2013, 714:202-209.
172. Mannstadt M., Harris M., Bravenboer B., Chitturi S., Dreijerink K.M.A., Lambright D.G., et al. N. Engl. J. Med. 2013, 368:2532-2534.
173. Nesbit M.A., Hannan F.M., Howles S.A., Babinsky V.N., Head R.A., Cranston T., et al. N. Engl. J. Med. 2013, 368:2476-2486.
174. Spiegel A.M. N. Engl. J. Med. 2013, 368:2515-2516.
175. Nebigil C.G., Choi D.S., Dierich A., Hickel P., Le Meur M., Messaddeq N., et al. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:9508-9513.
176. Giannessi D., Del Ry S., Vitale R.L. Pharmacol. Res. 2001, 43:111-126.
177. Yanagisawa H., Yanagisawa M., Kapur R.P., Richardson J.A., Williams S.C., Clouthier D.E., et al. Development 1998, 125:825-836.
178. Rapacciuolo A., Esposito G., Prasad S.V., Rockman H.A. Acta Physiol. Scand. 2001, 173:51-57.
179. Frey N., Olson E.N. Annu. Rev. Physiol. 2003, 65:45-79.
180. Hein L., Stevens M.E., Barsh G.S., Pratt R.E., Kobilka B.K., Dzau V.J. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:6391-6396.
181. Ikeda Y., Aihara K.-I., Sato T., Akaike M., Yoshizumi M., Suzaki Y., et al. J. Biol. Chem. 2005, 280:29661-29666.
182. Hunyady L., Catt K.J. Mol. Endocrinol. 2006, 20:953-970.
183. Liu Y.H., Yang X.P., Sharov V.G., Nass O., Sabbah H.N., Peterson E., et al. J. Clin. Invest. 1997, 99:1926-1935.
184. Liggett S. J. Clin. Invest. 2006, 116:1-3.
185. Wettschureck N., Rütten H., Zywietz A., Gehring D., Wilkie T.M., Chen J., et al. Nat. Med. 2001, 7:1236-1240.
186. Hunter J.J., Chien K.R. N. Engl. J. Med. 1999, 341:1276-1283.
187. Fan G., Jiang Y.-P., Lu Z., Martin D.W., Kelly D.J., Zuckerman J.M., et al. J. Biol. Chem. 2005, 280:40337-40346.
188. Adams J.W., Pagel a.L., Means C.K., Oksenberg D., Armstrong R.C., Brown J.H. Circ. Res. 2000, 87:1180-1187.
189. Dai D.-F., Johnson S.C., Villarin J.J., Chin M.T., Nieves-Cintrón M., Chen T., et al. Circ. Res. 2011, 108:837-846.
190. Adams J.W., Sakata Y., Davis M.G., Sah V.P., Wang Y., Liggett S.B., et al. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:10140-10145.
191. Harris I.S., Treskov I., Rowley M.W., Heximer S., Kaltenbronn K., Finck B.N., et al. Diabetes 2004, 53:3082-3090.
192. Filtz T.M., Grubb D.R., McLeod-Dryden T.J., Luo J., Woodcock E.a FASEB J. 2009, 23:3564-3570.
193. Grubb D.R., Luo J., Yu Y.L., Woodcock E.a FASEB J. 2012, 26:596-603.
194. Rohini A., Agrawal N., Koyani C.N., Singh R. Pharmacol. Res. 2010, 61:269-280.
195. Mishra S., Ling H., Grimm M., Zhang T., Bers D.M., Brown J.H. J. Cardiovasc. Pharmacol. 2010, 56:598-603.
196. Kehat I., Molkentin J.D. Circulation 2010, 122:2727-2735.
197. Dorn G., Force T. J. Clin. Invest. 2005, 115:527-537.
198. Braz J.C., Gregory K., Pathak A., Zhao W., Sahin B., Klevitsky R., et al. Nat. Med. 2004, 10:248-254.
199. Hahn H.S., Marreez Y., Odley A., Sterbling A., Yussman M.G., Hilty K.C., et al. Circ. Res. 2003, 93:1111-1119.
200. Bowman J.C., Steinberg S.F., Jiang T., Geenen D.L., Fishman G.I., Buttrick P.M. J. Clin. Invest. 1997, 100:2189-2195.
201. Wu G., Toyokawa T., Hahn H., Dorn G.W. J. Biol. Chem. 2000, 275:29927-29930.
202. Mochly-Rosen D., Wu G., Hahn H., Osinska H., Liron T., Lorenz J.N., et al. Circ. Res. 2000, 86:1173-1179.
203. Wang Y., Huang S., Sah V.P., Ross J., Brown J.H., Han J., et al. J. Biol. Chem. 1998, 273:2161-2168.
204. Wang Y., Su B., Sah V.P., Brown J.H., Han J., Chien K.R. J. Biol. Chem. 1998, 273:5423-5426.
205. Lorenz K., Schmitt J.P., Schmitteckert E.M., Lohse M.J. Nat. Med. 2009, 15:75-83.
206. Kehat I., Davis J., Tiburcy M., Accornero F., Saba-El-Leil M.K., Maillet M., et al. Circ. Res. 2011, 108:176-183.
207. Spruill L.S., McDermott P.J. FASEB J. 2006, 20:2133-2135.
208. Markou T., Cieslak D., Gaitanaki C., Lazou A. Mol. Cell. Biochem. 2009, 322:103-112.
209. Mende U., Semsarian C., Martins D.C., Kagen A., Duffy C., Schoen F.J., et al. J. Mol. Cell. Cardiol. 2001, 33:1477-1491.
210. Hayashi M., Lee J.-D. J. Mol. Med. (Berl.) 2004, 82:800-808.
211. Hayashi M. J. Clin. Invest. 2004, 113.
212. Nicol R.L., Frey N., Pearson G., Cobb M., Richardson J., Olson E.N. EMBO J. 2001, 20:2757-2767.
213. Xu J., Gong N.L., Bodi I., Aronow B.J., Backx P.H., Molkentin J.D. J. Biol. Chem. 2006, 281:9152-9162.
214. Kacimi R., Gerdes A.M. Hypertension 2003, 41:968-977.
215. Takeishi Y., Huang Q., Abe J., Glassman M., Che W., Lee J.D., et al. J. Mol. Cell. Cardiol. 2001, 33:1637-1648.
216. Kimura T.E., Jin J., Zi M., Prehar S., Liu W., Oceandy D., et al. Circ. Res. 2010, 106:961-970.
217. Decock J.B., Gillespie-Brown J., Parker P.J., Sugden P.H., Fuller S.J. FEBS Lett. 1994, 356:275-278.
218. Wu S.C., Solaro R.J. J. Biol. Chem. 2007, 282:30691-30698.
219. Borges L., Bigarella C.L., Baratti M.O., Crosara-Alberto D.P., Joazeiro P.P., Franchini K.G., et al. Biochem. Biophys. Res. Commun. 2008, 374:641-646.
220. Oh J.G., Jeong D., Cha H., Kim J.M., Lifirsu E., Kim J., et al. J. Mol. Cell. Cardiol. 2012, 53:53-63.
221. Shizukuda Y., Buttrick P.M. Am. J. Physiol. Heart Circ. Physiol. 2002, 282:H320-H327.
222. Phillipson A., Peterman E.E., Taormina P., Harvey M., Brue R.J., Atkinson N., et al. Am. J. Physiol. Heart Circ. Physiol. 2005, 289:H898-H907.
223. Rogers J.H., Tamirisa P., Kovacs A., Weinheimer C., Courtois M., Blumer K.J., et al. J. Clin. Invest. 1999, 104:567-576.
224. Yang J.M., Cho C.H., Kong K.A., Jang I.S., Kim H.W., Juhnn Y.S. Exp. Mol. Med. 1999, 31:179-184.
225. Tsang S., Woo A., Zhu W. Front. Biosci. 2010, 2:547-557.
226. Park-Windhol C., Zhang P., Zhu M., Su J., Chaves L., Maldonado A.E., et al. PLoS One 2012, 7:e40048.
227. Penela P., Murga C., Ribas C., Lafarga V., Mayor F. Br. J. Pharmacol. 2010, 160:821-832.
228. Maruyama Y. Circ. Res. 2002, 91:961-969.
229. Koch W.J., Lefkowitz R.J., Milano C.A., Akhter S.A., Rockman H.A. Adv. Pharmacol. 1998, 42:502-506.
230. Sorkin A., von Zastrow M. Nat. Rev. Mol. Cell Biol. 2009, 10:609-622.
231. Tsuboi K., Kawano T., Kozasa T. 3rd RGS Protein Colloq 2008.