메뉴 건너뛰기




Volumn 104, Issue 5, 1999, Pages 567-576

RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload

Author keywords

[No Author keywords available]

Indexed keywords

DOBUTAMINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 0032702983     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI6713     Document Type: Article
Times cited : (175)

References (46)
  • 1
    • 0030969371 scopus 로고    scopus 로고
    • The cellular and molecular response of cardiac myocytes to mechanical stress
    • Sadoshima, J., and Izumo, S. 1997. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu. Rev. Physiol. 59:551-571.
    • (1997) Annu. Rev. Physiol. , vol.59 , pp. 551-571
    • Sadoshima, J.1    Izumo, S.2
  • 2
    • 0028133410 scopus 로고
    • Mitogen-activated prorein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy
    • Thorburn, J., Frost, J.A., and Thorburn, A. 1994. Mitogen-activated prorein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy. J. Cell Biol. 126:1565-1572.
    • (1994) J. Cell Biol. , vol.126 , pp. 1565-1572
    • Thorburn, J.1    Frost, J.A.2    Thorburn, A.3
  • 3
    • 0025741345 scopus 로고
    • Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during α-adrenergic stimulation of neonatal rat ventricular cells
    • Knowlton, K.U., et al. 1991. Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during α-adrenergic stimulation of neonatal rat ventricular cells. J. Biol. Chem. 266:7759-7768.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7759-7768
    • Knowlton, K.U.1
  • 4
    • 0023713203 scopus 로고
    • Proto-oncogene induction and reprogramming of cardiac gene expression produced by pressure overload
    • Izumo, S., Nadal-Ginard, B., and Mahdavi, V. 1988. Proto-oncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc. Natl. Acad. Sci. USA. 85:339-343.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 339-343
    • Izumo, S.1    Nadal-Ginard, B.2    Mahdavi, V.3
  • 5
    • 0023938352 scopus 로고
    • α1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells: Effects on myosin light chain-2 gene expression
    • Lee, H., et al. 1988. α1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells: effects on myosin light chain-2 gene expression. J. Biol. Chem. 263:7352-7358.
    • (1988) J. Biol. Chem. , vol.263 , pp. 7352-7358
    • Lee, H.1
  • 6
    • 0025280867 scopus 로고
    • Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study
    • Levy, D., Garrison, R.J., Savage, D.D., Kannel, W.B., and Castelli, W.P. 1990. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N. Engl. J. Med. 322:1561-1566.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 1561-1566
    • Levy, D.1    Garrison, R.J.2    Savage, D.D.3    Kannel, W.B.4    Castelli, W.P.5
  • 7
    • 0026779779 scopus 로고
    • Hypertension, left ventricular hypertrophy, ventricular ectopy, and sudden death
    • Messerli, F.H., and Soria, F. 1992. Hypertension, left ventricular hypertrophy, ventricular ectopy, and sudden death. Am. J. Med. 93:21S-26S.
    • (1992) Am. J. Med. , vol.93
    • Messerli, F.H.1    Soria, F.2
  • 9
    • 0029869152 scopus 로고    scopus 로고
    • The athlete's heart: Is big beautiful?
    • Shepard, R.J. 1996. The athlete's heart: is big beautiful? Br. J. Sports. Med. 30:5-10.
    • (1996) Br. J. Sports. Med. , vol.30 , pp. 5-10
    • Shepard, R.J.1
  • 10
    • 0020411183 scopus 로고
    • Myocyte hypertrophy in neonatal rat cultures and its regulation by serum and by catecholamines
    • Simpson, P., McGrath, A., and Savion, S. 1982. Myocyte hypertrophy in neonatal rat cultures and its regulation by serum and by catecholamines. Circ. Res. 51:787-801.
    • (1982) Circ. Res. , vol.51 , pp. 787-801
    • Simpson, P.1    McGrath, A.2    Savion, S.3
  • 11
    • 0025221348 scopus 로고
    • Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes
    • Shubeita, H.E., et al. 1990. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. J. Biol. Chem. 265:20555-20562.
    • (1990) J. Biol. Chem. , vol.265 , pp. 20555-20562
    • Shubeita, H.E.1
  • 12
    • 0027182438 scopus 로고
    • Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts
    • Sadoshima, J., and Izumo, S. 1993. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Circ. Res. 73:413-423.
    • (1993) Circ. Res. , vol.73 , pp. 413-423
    • Sadoshima, J.1    Izumo, S.2
  • 13
    • 0027133262 scopus 로고
    • Functional coupling between endothelin receptors and multiple G-proteins in rat heart myocytes
    • Sokolovsky, M. 1993. Functional coupling between endothelin receptors and multiple G-proteins in rat heart myocytes. Receptors Channels. 1:295-304.
    • (1993) Receptors Channels , vol.1 , pp. 295-304
    • Sokolovsky, M.1
  • 14
    • 0028998174 scopus 로고
    • Identification of a domain in the angiotensin II type 1 receptor determining Gq coupling by the use of receptor chimeras
    • Wang, C., Jayadev, S., and Escobedo, J.A. 1995. Identification of a domain in the angiotensin II type 1 receptor determining Gq coupling by the use of receptor chimeras. J. Biol. Chem. 270:16677-16682.
    • (1995) J. Biol. Chem. , vol.270 , pp. 16677-16682
    • Wang, C.1    Jayadev, S.2    Escobedo, J.A.3
  • 15
    • 0022337599 scopus 로고
    • Acquisition by innervated cardiac myocytes of a pertussis toxin-specific regulatory protein linked to the alpha 1-receptor
    • Steinberg, S.F., Drugge, E.D., Bilezekian, J.P., and Robinson, R.B. 1985. Acquisition by innervated cardiac myocytes of a pertussis toxin-specific regulatory protein linked to the alpha 1-receptor. Science. 230:186-188.
    • (1985) Science , vol.230 , pp. 186-188
    • Steinberg, S.F.1    Drugge, E.D.2    Bilezekian, J.P.3    Robinson, R.B.4
  • 16
    • 0029013717 scopus 로고
    • Protein kinase cascade activated by mechanical stress in cardiocytes: Possible involvement of angiotensin II
    • Komuro, I., et al. 1995. Protein kinase cascade activated by mechanical stress in cardiocytes: possible involvement of angiotensin II. Eur. Heart J. 16(Suppl. C):8-11.
    • (1995) Eur. Heart J. , vol.16 , Issue.SUPPL. C , pp. 8-11
    • Komuro, I.1
  • 17
    • 0023062991 scopus 로고
    • G proteins: Transducers of receptor-generated signals
    • Gilman, A.G. 1987. G proteins: transducers of receptor-generated signals. Annu. Rev. Biochem. 56:615-649.
    • (1987) Annu. Rev. Biochem. , vol.56 , pp. 615-649
    • Gilman, A.G.1
  • 19
    • 0028860268 scopus 로고
    • Heterotrimeric G proteins: Organizers of transmembrane signals
    • Neer, E.J. 1995. Heterotrimeric G proteins: organizers of transmembrane signals. Cell. 80:249-257.
    • (1995) Cell , vol.80 , pp. 249-257
    • Neer, E.J.1
  • 20
    • 0030610854 scopus 로고    scopus 로고
    • Transgenic Gαq overexpression induces cardiac contractile failure in mice
    • D'Angelo, D.D., et al. 1997. Transgenic Gαq overexpression induces cardiac contractile failure in mice. Proc. Natl. Acad. Sci. USA. 94:8121-8126.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8121-8126
    • D'Angelo, D.D.1
  • 21
    • 0032506233 scopus 로고    scopus 로고
    • Transient cardiac expression of constitutively active Gαq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways
    • Mende, U., et al. 1998. Transient cardiac expression of constitutively active Gαq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Proc. Natl. Acad. Sci. USA. 95:13893-13898.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 13893-13898
    • Mende, U.1
  • 22
    • 0032562289 scopus 로고    scopus 로고
    • Targeting the receptor-Gq interface to inhibit in vivo pressure overload hypertrophy
    • Akhter, S.A., et al. 1998. Targeting the receptor-Gq interface to inhibit in vivo pressure overload hypertrophy. Science. 280:574-577.
    • (1998) Science , vol.280 , pp. 574-577
    • Akhter, S.A.1
  • 24
    • 0030029727 scopus 로고    scopus 로고
    • Inhibition of a G protein-mediated MAP kinase activation by a new mammalian gene family
    • Druey, K.M., Blumer, K.J., Kang, V.H., and Kehrl, J.H. 1996. Inhibition of a G protein-mediated MAP kinase activation by a new mammalian gene family. Nature. 379:742-746.
    • (1996) Nature , vol.379 , pp. 742-746
    • Druey, K.M.1    Blumer, K.J.2    Kang, V.H.3    Kehrl, J.H.4
  • 25
    • 0030032001 scopus 로고    scopus 로고
    • EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins
    • Koelle, M.R., and Horvitz, H.R. 1996. EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins. Cell. 84:115-125.
    • (1996) Cell , vol.84 , pp. 115-125
    • Koelle, M.R.1    Horvitz, H.R.2
  • 26
    • 0030576518 scopus 로고    scopus 로고
    • GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein α subunits
    • Berman, D.M., Wilkie, T.M., and Gilman, A.G. 1996. GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein α subunits. Cell. 86:445-452.
    • (1996) Cell , vol.86 , pp. 445-452
    • Berman, D.M.1    Wilkie, T.M.2    Gilman, A.G.3
  • 27
    • 0029808079 scopus 로고    scopus 로고
    • RGS family members: GTPase activating proteins for α subunits of heterotrimeric G proteins
    • Watson, N., Linder, M.E, Druey, K.M., Kehrl, J.H., and Blumer, K.J. 1996. RGS family members: GTPase activating proteins for α subunits of heterotrimeric G proteins. Nature. 382:172-175.
    • (1996) Nature , vol.382 , pp. 172-175
    • Watson, N.1    Linder, M.E.2    Druey, K.M.3    Kehrl, J.H.4    Blumer, K.J.5
  • 28
    • 0030610240 scopus 로고    scopus 로고
    • Attenuation of Gi- and Gq-mediared signaling by expression of RGS4 or GAIP in mammalian cells
    • Huang, C., Hepler, J.R., Gilman, A.G., and Mumby, S.M. 1997. Attenuation of Gi- and Gq-mediared signaling by expression of RGS4 or GAIP in mammalian cells. Proc. Natl. Acad. Sci. USA. 94:6159-6163.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6159-6163
    • Huang, C.1    Hepler, J.R.2    Gilman, A.G.3    Mumby, S.M.4
  • 29
    • 0031567582 scopus 로고    scopus 로고
    • Interaction of human retinal RGS with G-protein alpha-subunits
    • Natochin, M., Lipkin, V.M., and Artemyev, N.O. 1997. Interaction of human retinal RGS with G-protein alpha-subunits. FEBS Lett. 411:179-182.
    • (1997) FEBS Lett. , vol.411 , pp. 179-182
    • Natochin, M.1    Lipkin, V.M.2    Artemyev, N.O.3
  • 30
    • 0032004938 scopus 로고    scopus 로고
    • RGS3 and RGS4 are G protein inhibitors in the heart
    • Zhang, S., et al. 1998. RGS3 and RGS4 are G protein inhibitors in the heart. J. Mol. Cell. Cardiol. 30:269-276.
    • (1998) J. Mol. Cell. Cardiol. , vol.30 , pp. 269-276
    • Zhang, S.1
  • 31
    • 0031737333 scopus 로고    scopus 로고
    • Cardiac myocytes express mRNA for ten RGS proteins: Changes in RGS mRNA expression in ventricular myocytes and cultured atria
    • Kardestuncer, T., Wu, H., Lim, A.L., and Neer, E.J. 1998. Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expression in ventricular myocytes and cultured atria. FEBS Lett. 43:285-288.
    • (1998) FEBS Lett. , vol.43 , pp. 285-288
    • Kardestuncer, T.1    Wu, H.2    Lim, A.L.3    Neer, E.J.4
  • 32
    • 0032917612 scopus 로고    scopus 로고
    • RGS4 inhibits G protein signaling in cardiomyocytes
    • Tamirisa, P., Blumer, K.J., and Muslin, A.J. 1999. RGS4 inhibits G protein signaling in cardiomyocytes. Circulation. 99:441-447.
    • (1999) Circulation , vol.99 , pp. 441-447
    • Tamirisa, P.1    Blumer, K.J.2    Muslin, A.J.3
  • 33
    • 0026342911 scopus 로고
    • Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice
    • Subramaniam, A., et al. 1991. Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. J. Biol. Chem. 1266:24613-24620.
    • (1991) J. Biol. Chem. , vol.1266 , pp. 24613-24620
    • Subramaniam, A.1
  • 34
    • 0029939625 scopus 로고    scopus 로고
    • Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: Role for nuclear receptors in cardiac and brown adipose expression
    • Disch, D.L., et al. 1996. Transcriptional control of a nuclear gene encoding a mitochondrial fatty acid oxidation enzyme in transgenic mice: role for nuclear receptors in cardiac and brown adipose expression. Mol. Cell Biol. 16:4043-4051.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 4043-4051
    • Disch, D.L.1
  • 35
    • 0025873338 scopus 로고
    • Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy
    • Rockman, H.A., et al. 1991. Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy. Proc. Natl. Acad. Sci. USA. 88:8277-8281.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8277-8281
    • Rockman, H.A.1
  • 36
    • 0028067513 scopus 로고
    • Myosin heavy chain regulation and myocyte contractile depression after left ventricular hypertrophy in aortic-banded mice
    • Dorn, G.W., II, Robbins, J., Ball, N., and Walsh, R.A. 1994. Myosin heavy chain regulation and myocyte contractile depression after left ventricular hypertrophy in aortic-banded mice. Am. J. Physiol. 267:H400-H405.
    • (1994) Am. J. Physiol. , vol.267
    • Dorn G.W. II1    Robbins, J.2    Ball, N.3    Walsh, R.A.4
  • 37
    • 0032554670 scopus 로고    scopus 로고
    • Decompensation of pressure-overload hypertrophy in Gαq-overexpressing mice
    • Sakata, Y., Hoit, B.D., Liggett, S.B., Walsh, R.A., and Dorn, G.W., II. 1998. Decompensation of pressure-overload hypertrophy in Gαq-overexpressing mice. Circulation. 97:1488-1495.
    • (1998) Circulation , vol.97 , pp. 1488-1495
    • Sakata, Y.1    Hoit, B.D.2    Liggett, S.B.3    Walsh, R.A.4    Dorn G.W. II5
  • 38
    • 0029788179 scopus 로고    scopus 로고
    • Transthoracic echocardiography in models of cardiac disease in the mouse
    • Tanaka, N., et al. 1996. Transthoracic echocardiography in models of cardiac disease in the mouse. Circulation. 94:1109-1117.
    • (1996) Circulation , vol.94 , pp. 1109-1117
    • Tanaka, N.1
  • 39
    • 0032499733 scopus 로고    scopus 로고
    • Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
    • Rockman, H.A., et al. 1998. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc. Natl. Acad. Sci. USA 95:7000-7005.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7000-7005
    • Rockman, H.A.1
  • 40
    • 0030933063 scopus 로고    scopus 로고
    • MLP-deficient mice exhibit a disruption of cytoarchitectural organization, dilated cardiomyopathy, and heart failure
    • Arber, S., et al. 1997. MLP-deficient mice exhibit a disruption of cytoarchitectural organization, dilated cardiomyopathy, and heart failure. Cell. 88:393-403.
    • (1997) Cell , vol.88 , pp. 393-403
    • Arber, S.1
  • 41
    • 0029800177 scopus 로고    scopus 로고
    • Fatty acid oxidation enzyme gene expression is downregulated in the failing heart
    • Sack, M.N., et al. 1996. Fatty acid oxidation enzyme gene expression is downregulated in the failing heart. Circulation. 94:2837-2842.
    • (1996) Circulation , vol.94 , pp. 2837-2842
    • Sack, M.N.1
  • 42
    • 0024235209 scopus 로고
    • Positive inotropic effects in isolated ventricular myocardium from non-failing and terminally failing human hearts
    • Nabauer, M., et al. 1988. Positive inotropic effects in isolated ventricular myocardium from non-failing and terminally failing human hearts. Eur. J. Clin. Invest. 18:600-606.
    • (1988) Eur. J. Clin. Invest. , vol.18 , pp. 600-606
    • Nabauer, M.1
  • 43
    • 0025929351 scopus 로고
    • Functional consequences of cardiac hypertrophy and dilatation
    • Jacob, R., Brandle, M., Dierberger, B., and Rupp, H. 1991. Functional consequences of cardiac hypertrophy and dilatation. Basic Res. Cardiol. 86(Suppl. 1):113-130.
    • (1991) Basic Res. Cardiol. , vol.86 , Issue.SUPPL. 1 , pp. 113-130
    • Jacob, R.1    Brandle, M.2    Dierberger, B.3    Rupp, H.4
  • 44
    • 0025793981 scopus 로고
    • Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq
    • Smrcka, A.V., Hepler, J.R., Brown, K.O., and Sternweis, P.C. 1991. Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. Science. 251:804-807.
    • (1991) Science , vol.251 , pp. 804-807
    • Smrcka, A.V.1    Hepler, J.R.2    Brown, K.O.3    Sternweis, P.C.4
  • 45
    • 0025860413 scopus 로고
    • Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins
    • Taylor, S.J., Chae, H.Z., Rhee, S.G., and Exton, J.H. 1991. Activation of the beta 1 isozyme of phospholipase C by alpha subunits of the Gq class of G proteins. Nature. 350:516-518.
    • (1991) Nature , vol.350 , pp. 516-518
    • Taylor, S.J.1    Chae, H.Z.2    Rhee, S.G.3    Exton, J.H.4
  • 46
    • 0033574574 scopus 로고    scopus 로고
    • Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress
    • Hirota, H., et al. 1999. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell. 97:189-198.
    • (1999) Cell , vol.97 , pp. 189-198
    • Hirota, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.