An autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activation

Nature Structural and Molecular Biology

Volumn 18, Issue 9, 2011, Pages 999-1005

  Lyon, Angeline M ^a   Tesmer, Valerie M ^a   Dhamsania, Vishan D ^a   Thal, David M ^a   Gutierrez, Joanne ^b   Chowdhury, Shoaib ^b   Suddala, Krishna C ^a   Northup, John K ^b   Tesmer, John J G ^a,c  

^a UNIVERSITY OF MICHIGAN   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHOLIPASE C BETA;

ALLOSTERISM; ARTICLE; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME STRUCTURE; PRIORITY JOURNAL;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; LOLIGO; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASE C BETA; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEPIA;

CEPHALOPODA; INVERTEBRATA;

EID: 80052463082     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2095     Document Type: Article

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