A Genome-wide RNAi Screen Reveals a Trio-Regulated Rho GTPase Circuitry Transducing Mitogenic Signals Initiated by G Protein-Coupled Receptors

Molecular Cell

Volumn 49, Issue 1, 2013, Pages 94-108

  Vaqué, Jose P ^a   Dorsam, Robert T ^b   Feng, Xiaodong ^a,c   Iglesias Bartolome, Ramiro ^a   Forsthoefel, David J ^d   Chen, Qianming ^c   Debant, Anne ^e   Seeger, Mark A ^d   Ksander, Bruce R ^f   Teramoto, Hidemi ^g   Gutkind, J Silvio ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c SICHUAN UNIVERSITY   (China)

^d OHIO STATE UNIVERSITY   (United States)

^e CNRS   (France)

^f SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^g Kojin Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE C BETA; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SYNTHETIC BIOLOGY;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CLOZAPINE; DROSOPHILA; DROSOPHILA PROTEINS; ENZYME ACTIVATION; FEMALE; GENE KNOCKDOWN TECHNIQUES; GTP-BINDING PROTEIN ALPHA SUBUNITS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASES; MITOGENS; MITOSIS; NEOPLASM TRANSPLANTATION; NEOPLASMS; NIH 3T3 CELLS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, G-PROTEIN-COUPLED; RHO GTP-BINDING PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 84872266242     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2012.10.018     Document Type: Article

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