The lipid raft proteins flotillins/reggies interact with Gαq and are involved in Gq-mediated p38 mitogen-activated protein kinase activation through tyrosine kinase

Cellular Signalling

Volumn 19, Issue 6, 2007, Pages 1301-1308

  Sugawara, Yo ^a   Nishii, Hiroko ^a   Takahashi, Tomoko ^a   Yamauchi, Junji ^a   Mizuno, Norikazu ^a   Tago, Kenji ^a   Itoh, Hiroshi ^a  

^a Graduate School of Biological Sciences   (Japan)

Author keywords

Flotillin reggie; Gq; Lipid rafts; p38 MAPK; Src tyrosine kinase

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; FLOTILLIN 1; FLOTILLIN 2; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; METHYL BETA CYCLODEXTRIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA; URIDINE TRIPHOSPHATE;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; LIPID RAFT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

BETA-CYCLODEXTRINS; CELL LINE; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HELA CELLS; HUMANS; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; RECEPTORS, PURINERGIC P2; SRC-FAMILY KINASES; TWO-HYBRID SYSTEM TECHNIQUES; URIDINE TRIPHOSPHATE;

EID: 34147166070     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2007.01.012     Document Type: Article

References (40)

1. Gilman A.G. Annu. Rev. Biochem. 56 (1987) 615
2. Neves S.R., Ram P.T., and Iyengar R. Science 296 (2002) 1636
3. Hubbard K.B., and Hepler J.R. Cell. Signal. 18 (2006) 135
4. Brown D.A., and London E. J. Biol. Chem. 275 (2000) 17221
5. Simons K., and Toomre D. Nat. Rev. Mol. Cell Biol. 1 (2000) 31
6. Pike L.J. J. Lipid Res. 44 (2003) 655
7. Ostrom R.S., and Insel P.A. Br. J. Pharmacol. 143 (2004) 235
8. Jio X., Zhang N., Xu X., Oppenheim J.J., and Jin T. Mol. Cell. Biol. 25 (2005) 5752
9. Schulte T., Paschke K.A., Laessing U., Lottspeich F., and Stuermer C.A. Development 124 (1997) 577
10. Bickel P.E., Scherer P.E., Schnitzer J.E., Oh P., Lisanti M.P., and Lodish H.F. J. Biol. Chem. 272 (1997) 13793
11. Tavernarakis N., Driscoll M., and Kyrpides N.C. Trends Biochem. Sci. 24 (1999) 425
12. Galbiati F., Volonte D., Goltz J.S., Steele Z., Sen J., Jurcsak J., Stein D., Stevens L., and Lisanti M.P. Gene 210 (1998) 229
13. von Philipsborn A.C., Ferrer-Vaquer A., Rivera-Milla E., Stuermer C.A., and Malaga-Trillo E. J. Comp. Neurol. 428 (2005) 257
14. Volonté D., Galbiati F., Li S., Nishiyama K., Okamoto T., and Lisanti M.P. J. Biol. Chem. 274 (1999) 12702
15. Iida S., Kohro T., Kodama T., Nagata S., and Fukunaga R. J. Leukoc. Biol. 78 (2005) 481
16. Kokubo H., Lemere C.A., and Yamaguchi H. Neurosci. Lett. 290 (2000) 93
17. Hazarika P., McCarty M.F., Prieto V.G., George S., Babu D., Koul D., Bar-Eli M., and Duvic M. Cancer Res. 64 (2004) 7361
18. Kozasa T. Methods Mol. Biol. 237 (2004) 21
19. Carman C.V., Parent J.L., Day P.W., Pronin A.N., Sternweis P.M., Wedegaertner P.B., Gilman A.G., Benovic J.L., and Kozasa T. J. Biol. Chem. 274 (1999) 34483
20. Tall G.G., Krumins A.M., and Gilman A.G. J. Biol. Chem. 278 (2003) 8356
21. Nishimura A., Okamoto M., Sugawara Y., Mizuno N., Yamauchi J., and Itoh H. Genes Cells 11 (2006) 487
22. Gutkind J.S. J. Biol. Chem. 273 (1998) 1839
23. Takasaki J., Saito T., Taniguchi M., Kawasaki T., Moritani Y., Hayashi K., and Kobori M. J. Biol. Chem. 279 (2004) 47438
24. Nagao M., Yamauchi J., Kaziro Y., and Itoh H. J. Biol. Chem. 273 (1998) 22892
25. Hoehne M., de Couet H.G., Stuermer C.A., and Fischbach K.F. Mol. Cell. Neurosci. 30 (2005) 326
26. Siderovski D.P., and Willard F.S. Int. J. Biol. Sci. 1 (2005) 51
27. Rajendran L., Masilamani M., Solomon S., Tikkanen R., Stuermer C.A., Plattner H., and Illges H. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 8241
28. Langhorst M.F., Reuter A., Luxenhofer G., Boneberg E.M., Legler D.F., Plattner H., and Stuermer C.A. FASEB J. 20 (2006) 711
29. Kato N., Nakanishi M., and Hirashima N. J. Immunol. 177 (2006) 147
30. Baumann C.A., Ribon V., Kanzaki M., Thurmond D.C., Mora S., Shigematsu S., Bickel P.E., Pessin J.E., and Saltiel A.R. Nature 407 (2000) 202
31. Zhang Y., Neo S.Y., Han J., Yaw L.P., and Lin S.C. J. Biol. Chem. 274 (1999) 2851
32. Hiol A., Davey P.C., Osterhout J.L., Waheed A.A., Fischer E.R., Chen C.K., Milligan G., Druey K.M., and Jones T.L. J. Biol. Chem. 278 (2003) 19301
33. Luttrell D.K., and Luttrell L.M. Oncogene 23 (2004) 7969
34. Rodríguez-Fernández J.L., and Rozengurt E. J. Biol. Chem. 271 (1996) 27895
35. Liu J., Deyoung S.M., Zhang M., Dold L.H., and Saltiel A.R. J. Biol. Chem. 280 (2005) 16125
36. Stuermer C.A., Lang D.M., Kirsch F., Wiechers M., Deininger S.O., and Plattner H. Mol. Biol. Cell 12 (2001) 3031
37. Santamaría A., Castellanos E., Gomez V., Benedit P., Renau-Piqueras J., Morote J., Reventos J., Thomson T.M., and Paciucci R. Mol. Cell. Biol. 25 (2005) 1900
38. Ono K., and Han J. Cell. Signal. 12 (2000) 1
39. Cavalli V., Vilbois F., Corti M., Marcote M.J., Tamura K., Karin M., Arkinstall S., and Gruenberg J. Mol. Cell 7 (2001) 421
40. Macé G., Miaczynska M., Zerial M., and Nebreda A.R. EMBO J. 24 (2005) 3235