LARG links histamine-H1-receptor-activated G q to Rho-GTPase-dependent signaling pathways

Cellular Signalling

Volumn 24, Issue 3, 2012, Pages 652-663

  Pfreimer, Mariana ^a   Vatter, Petra ^a   Langer, Torben ^a   Wieland, Thomas ^b   Gierschik, Peter ^a   Moepps, Barbara ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Heterotrimeric G protein G q; Histamine H1 receptor; Leukemia associated Rho guanine nucleotide exchange factor (LARG); Phospholipase C; Rho; Serum response factor

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HISTAMINE H1 RECEPTOR; LEUKEMIA ASSOCIATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; PLECKSTRIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL STRAIN COS7; CONTROLLED STUDY; ENZYME ACTIVATION; HELA CELL; INTRACELLULAR SIGNALING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MOLECULAR SEQUENCE DATA; PDZ DOMAINS; PHOSPHOLIPASE C BETA; RECEPTORS, HISTAMINE H1; RHO GTP-BINDING PROTEINS; SERUM RESPONSE FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84855586361     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.10.014     Document Type: Article

References (83)

1. Heasman S.J., Ridley A.J. Nat. Rev. Mol. Cell Biol. 2008, 9:690-701.
2. Hall A. Cancer Metastasis Rev. 2009, 28:5-14.
3. Rossman K.L., Sondek J. Trends Biochem. Sci. 2005, 30:163-165.
4. Meller N., Merlot S., Guda C. J. Cell Sci. 2005, 118:4937-4946.
5. Aittaleb M., Boguth C.A., Tesmer J.J. Mol. Pharmacol. 2010, 77:111-125.
6. Sternweis P.C., Carter A.M., Chen Z., Danesh S.M., Hsiung Y.F., Singer W.D. Adv. Protein Chem. 2007, 74:189-228.
7. Kourlas P.J., Strout M.P., Becknell B., Veronese M.L., Croce C.M., Theil K.S., Krahe R., Ruutu T., Knuutila S., Bloomfield C.D., Caligiuri M.A. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:2145-2150.
8. Hart M.J., Jiang X., Kozasa T., Roscoe W., Singer W.D., Gilman A.G., Sternweis P.C., Bollag G. Science 1998, 280:2112-2114.
9. Wells C.D., Liu M.Y., Jackson M., Gutowski S., Sternweis P.M., Rothstein J.D., Kozasa T., Sternweis P.C. J. Biol. Chem. 2002, 277:1174-1181.
10. Suzuki N., Nakamura S., Mano H., Kozasa T. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:733-738.
11. Suzuki N., Tsumoto K., Hajicek N., Daigo K., Tokita R., Minami S., Kodama T., Hamakubo T., Kozasa T. J. Biol. Chem. 2009, 284:5000-5009.
12. Booden M.A., Siderovski D.P., Der C.J. Mol. Cell. Biol. 2002, 22:4053-4061.
13. Fukuhara S., Chikumi H., Gutkind J.S. FEBS Lett. 2000, 485:183-188.
14. Chikumi H., Vázquez-Prado J., Servitja J.M., Miyazaki H., Gutkind J.S. J. Biol. Chem. 2002, 277:27130-27134.
15. Kozasa T., Jiang X., Hart M.J., Sternweis P.M., Singer W.D., Gilman A.G., Bollag G., Sternweis P.C. Science 1998, 280:2109-2111.
16. Moepps B., Tulone C., Kern C., Minisini R., Michels G., Vatter P., Wieland T., Gierschik P. Cell. Signal. 2008, 20:1528-1537.
17. Heximer S.P., Watson N., Linder M.E., Blumer K.J., Hepler J.R. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:14389-14393.
18. Illenberger D., Walliser C., Nurnberg B., Diaz Lorente M., Gierschik P. J. Biol. Chem. 2003, 278:3006-3014.
19. Hill C.S., Wynne J., Treisman R. Cell 1995, 81:1159-1170.
20. García-Mata R., Wennerberg K., Arthur W.T., Noren N.K., Ellerbroek S.M., Burridge K. Methods Enzymol. 2006, 406:425-437.
21. Meyer S.L. Data Analysis for Scientists and Engineers 1975, 39-48. Peer Management Consultants, Ltd, Evanston.
22. Greco W., Unkelbach H.-D., Pöch G., Sühnel J., Kundi M., Bödeker W. Arch. Complex Environ. Stud. 1992, 4:65-69.
23. Lutz S., Shankaranarayanan A., Coco C., Ridilla M., Nance M.R., Vettel C., Baltus D., Evelyn C.R., Neubig R.R., Wieland T., Tesmer J.J. Science 2007, 318:1923-1927.
24. Yamada T., Ohoka Y., Kogo M., Inagaki S. J. Biol. Chem. 2005, 280:19358-19363.
25. Choi J.W., Herr D.R., Noguchi K., Yung Y.C., Lee C.-W., Mutoh T., Lin M.-E., Teo S.T., Park K.E., Mosley A.N., Chun J. Annu. Rev. Pharmacol. Toxicol. 2010, 50:157-186.
26. Suh P.G., Hwang J.I., Ryu S.H., Donowitz M., Kim J.H. Biochem. Biophys. Res. Commun. 2001, 288:1-7.
27. Kim J.K., Lim S., Kim J., Kim S., Kim J.H., Ryu S.H., Suh P.G. Adv. Enzyme Regul. 2011, 51:138-151.
28. Katoh H., Aoki J., Yamaguchi Y., Kitano Y., Ichikawa A., Negishi M. J. Biol. Chem. 1998, 273:28700-28707.
29. Sagi S.A., Seasholtz T.M., Kobiashvili M., Wilson B.A., Toksoz D., Brown J.H. J. Biol. Chem. 2001, 276:15445-15452.
30. Lin K., Wang D., Sadee W. J. Biol. Chem. 2002, 43:40789-40798.
31. Hao S., Kurosaki T., August A. EMBO J. 2003, 22:4166-4177.
32. Keller P.J., Gable C.M., Wing M.R., Cox A.D. Cancer Res. 2005, 65:9883-9890.
33. Zheng M., Cierpicki T., Momotani K., Artamonov M.V., Derewenda U., Bushweller J.H., Somlyo A.V., Derewenda Z.S. BMC Struct. Biol. 2009, 9:36.
34. Chen Z., Guo L., Sprang S.R., Sternweis P.C. Protein Sci. 2011, 20:107-117.
35. Tilly B.C., Tertoolen L.G., Lambrechts A.C., Remorie R., de Laat S.W., Moolenaar W.H. Biochem. J. 1990, 266:235-243.
36. O'Brien M., Flynn D., Mullins B., Morrison J.J., Smith T.J. Reprod. Biol. Endocrinol. 2008, 6:1.
37. Dubash A.D., Wennerberg K., García-Mata R., Menold M.M., Arthur W.T., Burridge K. J. Cell Sci. 2007, 120:3989-3998.
38. Guilluy C., Brégeon J., Toumaniantz G., Rolli-Derkinderen M., Retailleau K., Loufrani L., Henrion D., Scalbert E., Bril A., Torres R.M., Offermanns S., Pacaud P., Loirand G. Nat. Med. 2010, 16:183-190.
39. Hill S.J., Chazot P., Fukui H., Ganellin C.R., Haas H.L., Hills R., Levi R., Schunack W., Schwartz J.-C., Shankley N.P., Timmerman H., Young J.M. Histamine receptors http://www.iuphar-db.org/DATABASE/FamilyMenuForward?familyId=33.
40. Vogt S., Grosse R., Schultz G., Offermanns S. J. Biol. Chem. 2003, 278:28743-28749.
41. Kristelly R., Gao G., Tesmer J.J. J. Biol. Chem. 2004, 279:47352-47362.
42. Jaiswal M., Gremer L., Dvorsky R., Haeusler L.C., Cirstea I.C., Uhlenbrock K., Ahmadian M.R. J. Biol. Chem. 2011, 286:18202-18212.
43. Berman D.M., Kozasa T., Gilman A.G. J. Biol. Chem. 1996, 271:27209-27212.
44. Lambert N.A., Johnston C.A., Cappell S.D., Kuravi S., Kimple A.J., Willard F.S., Siderovski D.P. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:7066-7071.
45. Kimple A.J., Bosch D.E., Giguère P.M., Siderovski D.P. Pharmacol. Rev. 2011, 63:728-749.
46. Lee H.J., Zheng J.J. Cell Commun. Signal. 2010, 8:8.
47. Aurandt J., Vikis H.G., Gutkind J.S., Ahn N., Guan K.L. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:12085-12090.
48. Swiercz J.M., Kuner R., Behrens J., Offermanns S. Neuron 2002, 35:51-63.
49. Taya S., Inagaki N., Sengiku H., Makino H., Iwamatsu A., Urakawa I., Nagao K., Kataoka S., Kaibuchi K. J. Cell. Biol. 2001, 155:809-820.
50. Bourguignon L.Y., Gilad E., Brightman A., Diedrich F., Singleton P. J. Biol. Chem. 2006, 281:14026-14040.
51. Okuhira K., Fitzgerald M.L., Tamehiro N., Ohoka N., Suzuki K., Sawada J., Naito M., Nishimaki-Mogami T. J. Biol. Chem. 2010, 285:16369-16377.
52. Liu J., Zhang J., Yang Y., Huang H., Shen W., Hu Q., Wang X., Wu J., Shi Y. Protein Sci. 2008, 17:1003-1014.
53. Wang S.J., Wong G., de Heer A.M., Xia W., Bourguignon L.Y. Laryngoscope 2009, 119:1518-1530.
54. Smietana K., Kasztura M., Paduch M., Derewenda U., Derewenda Z.S., Otlewski J. Acta Biochim. Pol. 2008, 55:269-280.
55. Grabocka E., Wedegaertner P.B. Mol. Pharmacol. 2007, 72:993-1002.
56. Aghazadeh B., Lowry W.E., Huang X.Y., Rosen M.K. Cell 2000, 102:625-633.
57. Yohe M.E., Rossman K.L., Gardner O.S., Karnoub A.E., Snyder J.T., Gershburg S., Graves L.M., Der C.J., Sondek J. J. Biol. Chem. 2007, 282:13813-13823.
58. Wells C.D., Gutowski S., Bollag G., Sternweis P.C. J. Biol. Chem. 2001, 276:28897-28905.
59. Fukuhara S., Murga C., Zohar M., Igishi T., Gutkind J.S. J. Biol. Chem. 1999, 274:5868-5879.
60. Waldo G.L., Ricks T.K., Hicks S.N., Cheever M.L., Kawano T., Tsuboi K., Wang X., Montell C., Kozasa T., Sondek J., Harden T.K. Science 2010, 330:974-980.
61. Van Raamsdonk C.D., Bezrookove V., Green G., Bauer J., Gaugler L., O'Brien J.M., Simpson E.M., Barsh G.S., Bastian B.C. Nature 2009, 457:599-602.
62. Küsters-Vandevelde H.V., van Engen-van Grunsven I.A., Küsters B., van Dijk M.R., Groenen P.J., Wesseling P., Blokx W.A. Acta Neuropathol. 2010, 120:755-764.
63. Lamba S., Felicioni L., Buttitta F., Bleeker F.E., Malatesta S., Corbo V., Scarpa A., Rodolfo M., Knowles M., Frattini M., Marchetti A., Bardelli A. PLoS One 2009, 4:e6833.
64. Pópulo H., Vinagre J., Lopes J.M., Soares P. Br. J. Ophthalmol. 2011, 95:715-719.
65. Sisley K., Doherty R., Cross N.A. Br. J. Ophthalmol. 2011, 95:620-623.
66. Gene Expression Atlas accessed on 24.8.2011. http://www.ebi.ac.uk/gxa/gene?gid=Q9NZN5.
67. Kitzing T.M., Sahadevan A.S., Brandt D.T., Knieling H., Hannemann S., Fackler O.T., Grosshans J., Grosse R. Genes Dev. 2007, 21:1478-1483.
68. Clark E.A., Golub T.R., Lander E.S., Hynes R.O. Nature 2000, 406:532-535.
69. Ruth M.C., Xu Y., Maxwell I.H., Ahn N.G., Norris D.A., Shellman Y.G. J. Invest. Dermatol. 2006, 126:862-868.
70. Sanz-Moreno V., Gadea G., Ahn J., Paterson H., Marra P., Pinner S., Sahai E., Marshall C.J. Cell 2008, 135:510-523.
71. Bravo-Cordero J.J., Oser M., Chen X., Eddy R., Hodgson L., Condeelis J. Curr. Biol. 2011, 21:635-644.
72. Bartolomé R.A., Wright N., Molina-Ortiz I., Sánchez-Luque F.J., Teixidó J. Cancer Res. 2008, 68:8221-8230.
73. Tilly B.C., Tertoolen L.G., Remorie R., Ladoux A., Verlaan I., de Laat S.W., Moolenaar W.H. J Cell Biol. 1990, 110:1211-1215.
74. Jangi S.M., Díaz-Pérez J.L., Ochoa-Lizarralde B., Martín-Ruiz I., Asumendi A., Pérez-Yarza G., Gardeazabal J., Díaz-Ramón J.L., Boyano M.D. Carcinogenesis 2006, 27:1787-1796.
75. Haak-Frendscho M., Darvas Z., Hegyesi H., Kárpáti S., Hoffman R.L., László V., Bencsáth M., Szalai C., Fürész J., Timár J., Bata-Csörgõ Z., Szabad G., Pivarcsi A., Pállinger E., Kemény L., Horváth A., Dobozy A., Falus A. J. Invest. Dermatol. 2000, 115:345-352.
76. Darvas Z., Sakurai E., Schwelberger H.G., Hegyesi H., Rivera E., Othsu H., Watanabe T., Pállinger E., Falus A. Melanoma Res. 2003, 13:239-246.
77. Pollock P.M., Cohen-Solal K., Sood R., Namkoong J., Martino J.J., Koganti A., Zhu H., Robbins C., Makalowska I., Shin S.S., Marin Y., Roberts K.G., Yudt L.M., Chen A., Cheng J., Incao A., Pinkett H.W., Graham C.L., Dunn K., Crespo-Carbone S.M., Mackason K.R., Ryan K.B., Sinsimer D., Goydos J., Reuhl K.R., Eckhaus M., Meltzer P.S., Pavan W.J., Trent J.M., Chen S. Nat. Genet. 2003, 34:108-112.
78. Marín Y.E., Namkoong J., Cohen-Solal K., Shin S.S., Martino J.J., Oka M., Chen S. Cell. Signal. 2006, 18:1279-1286.
79. Bittner M., Meltzer P., Chen Y., Jiang Y., Seftor E., Hendrix M., Radmacher M., Simon R., Yakhini Z., Ben-Dor A., Sampas N., Dougherty E., Wang E., Marincola F., Gooden C., Lueders J., Glatfelter A., Pollock P., Carpten J., Gillanders E., Leja D., Dietrich K., Beaudry C., Berens M., Alberts D., Sondak V. Nature 2000, 406:536-540.
80. Dissanayake S.K., Wade M., Johnson C.E., O'Connell M.P., Leotlela P.D., French A.D., Shah K.V., Hewitt K.J., Rosenthal D.T., Indig F.E., Jiang Y., Nickoloff B.J., Taub D.D., Trent J.M., Moon R.T., Bittner M., Weeraratna A.T. J. Biol. Chem. 2007, 282:17259-17271.
81. Shin M.K., Levorse J.M., Ingram R.S., Tilghman S.M. Nature 1999, 402:496-501.
82. Longenecker K.L., Lewis M.E., Chikumi H., Gutkind J.S., Derewenda Z.S. Structure 2001, 9:559-569.
83. Cole C., Barber J.D., Barton G.J. Nucleic Acids Res. 2008, 36:W197-W201.