Signaling efficiency of Gaq through its effectors p63RhoGEF and GEFT depends on their subcellular location

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Goedhart, Joachim ^a   Van Unen, Jakobus ^a   Adjobo Hermans, Merel J W ^a,b   Gadella, Theodorus W J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; GEFT PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; P63RHOGEF PROTEIN, HUMAN; PHOSPHOLIPASE C BETA; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; BIOLOGICAL MODEL; CALCIUM SIGNALING; CELL MEMBRANE; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOPLASM; GENE EXPRESSION; GENE ONTOLOGY; GENE VECTOR; GENETICS; HELA CELL; HUMAN; INTRACELLULAR SPACE; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; HELA CELL LINE;

AMINO ACID SEQUENCE; CALCIUM SIGNALING; CELL MEMBRANE; CYSTEINE; CYTOPLASM; GENE EXPRESSION; GENE ONTOLOGY; GENETIC VECTORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; INTRACELLULAR SPACE; KINETICS; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE C BETA; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN TRANSPORT; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; SIGNAL TRANSDUCTION;

EID: 84891632925     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep02284     Document Type: Article

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