N-terminal polybasic motifs are required for plasma membrane localization of Gαs and Gαq

Cellular Signalling

Volumn 20, Issue 10, 2008, Pages 1900-1910

  Crouthamel, Marykate ^a   Thiyagarajan, Manimekalai M ^a   Evanko, Daniel S ^a   Wedegaertner, Philip B ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Heterotrimeric G protein; Membrane targeting; Palmitoylation; Subcellular localization

Indexed keywords

CYCLIC AMP; GLUTAMIC ACID; GLUTAMINE; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT Q; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT S; INOSITOL PHOSPHATE; MEMBRANE LIPID; MUTANT PROTEIN;

ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; CELL MEMBRANE; EMBRYO; FRACTIONATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; MOLECULAR INTERACTION; MUTATION; MYRISTYLATION; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEFECT; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE; CELL MEMBRANE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HUMANS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; MYRISTIC ACID; PROTEIN CONFORMATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 49549123353     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2008.06.019     Document Type: Article

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