Assembly of high order Gαq-effector complexes with RGS proteins

Journal of Biological Chemistry

Volumn 283, Issue 50, 2008, Pages 34923-34934

  Shankaranarayanan, Aruna ^a,b   Thal, David M ^a   Tesmer, Valerie M ^a   Roman, David L ^c,e   Neubig, Richard R ^c   Kozasa, Tohru ^d   Tesmer, John J G ^a,c,f  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^e UNIVERSITY OF IOWA   (United States)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BINDING SITES; CHEMICAL ACTIVATION; FLOW CYTOMETRY; GALLIUM ALLOYS; SIGNAL TRANSDUCTION; TRANSCRIPTION;

ACTIVATING PROTEINS; ALLOSTERIC MODULATORS; BONA FIDE; COUPLED RECEPTORS; CRYSTALLOGRAPHIC STUDIES; G PROTEINS; GAP ACTIVITIES; GENE TRANSCRIPTIONS; HIGH ORDERS; LESSER EXTENTS; MAGNITUDE RESPONSES; PHYSIOLOGICAL PROCESSES; PROTEIN INTERACTIONS; PROTEIN SIGNALING; SIGNAL TRANSDUCTION PATHWAYS; SMOOTH MUSCLES; TERNARY COMPLEXES; TRANSMEMBRANE SIGNALING;

PROTEINS;

G PROTEIN COUPLED RECEPTOR KINASE 2; RGS PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; BINDING, COMPETITIVE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; G-PROTEIN-COUPLED RECEPTOR KINASE 2; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; KINETICS; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RGS PROTEINS;

EID: 58049192385     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805860200     Document Type: Article

References (77)

1. Gilman, A. G. (1987) Annu. Rev. Biochem. 56, 615-649
2. Neves, S. R., Ram, P. T., and Iyengar, R. (2002) Science 296, 1636-1639
3. Berstein, G., Blank, J. L., Jhon, D. Y., Exton, J. H., Rhee, S. G., and Ross, E. M. (1992) Cell 70, 411-418
4. Kozasa, T., Jiang, X., Hart, M. J., Sternweis, P. M., Singer, W. D., Gilman, A. G., Bollag, G., and Sternweis, P. C. (1998) Science 280, 2109-2111
5. Berman, D. M., Wilkie, T. M., and Gilman, A. G. (1996) Cell 86, 445-452
6. Watson, N., Linder, M. E., Druey, K. M., Kehrl, J. H., and Blumer, K. J. (1996) Nature 383, 172-175
7. Zhong, H., Wade, S. M., Woolf, P. J., Linderman, J. J., Traynor, J. R., and Neubig, R. R. (2003) J. Biol. Chem. 278, 7278-7284
8. Mukhopadhyay, S., and Ross, E. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9539-9544
9. Tesmer, J. J. G., Berman, D. M., Gilman, A. G., and Sprang, S. R. (1997) Cell 89, 251-261
10. Tesmer, J., Sunahara, R., Gilman, A., and Sprang, S. (1997) Science 278, 1907-1916
11. Sunahara, R. K., Tesmer, J. J. G., Gilman, A. G., and Sprang, S. R. (1997) Science 278, 1943-1947
12. Sprang, S. R., Chen, Z., and Du, X. (2007) Adv. Protein Chem. 74, 1-65
13. Arshavsky, V., and Bownds, M. D. (1992) Nature 357, 416-417
14. He, W., Cowan, C. W., and Wensel, T. G. (1998) Neuron 20, 95-102
15. McEntaffer, R. L., Natochin, M., and Artemyev, N. O. (1999) Biochemistry 38, 4931-4937
16. Skiba, N. P., Yang, C. S., Huang, T., Bae, H., and Hamm, H. E. (1999) J. Biol. Chem. 274, 8770-8778
17. Slep, K. C., Kercher, M. A., He, W., Cowan, C. W., Wensel, T. G., and Sigler, P. B. (2001) Nature 409, 1071-1077
18. Nekrasova, E., Berman, D., Rustandi, R., Hamm, H., Gilman, A., and Arshavsky, V. (1997) Biochemistry 36, 7638-7643
19. Natochin, M., Granovsky, A. E., and Artemyev, N. O. (1997) J. Biol. Chem. 272, 17444-17449
20. Wieland, T., Chen, C. K., and Simon, M. I. (1997) J. Biol. Chem. 272, 8853-8856
21. Offermanns, S., and Simon, M. I. (1998) Oncogene 17, 1375-1381
22. Hubbard, K. B., and Hepler, J. R. (2006) Cell. Signal. 18, 135-150
23. Dorn, G. W., Jr., and Force, T. (2005) J. Clin. Investig. 115, 527-537
24. Harris, D. M., Cohn, H. I., Pesant, S., Zhou, R. H., and Eckhart, A. D. (2007) Am. J. Physiol. Heart Circ. Physiol. 293, 3072-3079
25. Rhee, S. G. (2001) Annu. Rev. Biochem. 70, 281-312
26. Lutz, S., Freichel-Blomquist, A., Yang, Y., Rumenapp, U., Jakobs, K. H., Schmidt, M., and Wieland, T. (2005) J. Biol. Chem. 280, 11134-11139
27. Lutz, S., Shankaranarayanan, A., Coco, C., Ridilla, M., Nance, M. R., Vettel, C., Baltus, D., Evelyn, C. R., Neubig, R. R., Wieland, T., and Tesmer, J. J. (2007) Science 318, 1923-1927
28. Williams, S. L., Lutz, S., Charlie, N. K., Vettel, C., Ailion, M., Coco, C., Tesmer, J. J., Jorgensen, E. M., Wieland, T., and Miller, K. G. (2007) Genes Dev. 21, 2731-2746
29. Rojas, R. J., Yohe, M. E., Gershburg, S., Kawano, T., Kozasa, T., and Sondek, J. (2007) J. Biol. Chem. 282, 29201-29210
30. Theilade, J., Haunso, S., and Sheikh, S. P. (2001) Curr. Drug Targets Immune Endocr. Metabol. Dis. 1, 139-151
31. Pitcher, J. A., Freedman, N. J., and Lefkowitz, R. J. (1998) Annu. Rev. Biochem. 67, 653-692
32. Willets, J. M., Nahorski, S. R., and Challiss, R. A. (2005) J. Biol. Chem. 280, 18950-18958
33. Willets, J. M., Nash, M. S., Challiss, R. A., and Nahorski, S. R. (2004) J. Neurosci. 24, 4157-4162
34. Iwata, K., Luo, J., Penn, R. B., and Benovic, J. L. (2005) J. Biol. Chem. 280, 2197-2204
35. Sterne-Marr, R., Tesmer, J. J., Day, P. W., Stracquatanio, R. P., Cilente, J. A., O'Connor, K. E., Pronin, A. N., Benovic, J. L., and Wedegaertner, P. B. (2003) J. Biol. Chem. 278, 6050-6058
36. Tesmer, V. M., Kawano, T., Shankaranarayanan, A., Kozasa, T., and Tesmer, J. J. (2005) Science 310, 1686-1690
37. Usui, I., Imamura, T., Babendure, J. L., Satoh, H., Lu, J. C., Hupfeld, C. J., and Olefsky, J. M. (2005) Mol. Endocrinol. 19, 2760-2768
38. Peregrin, S., Jurado-Pueyo, M., Campos, P. M., Sanz-Moreno, V., Ruiz-Gomez, A., Crespo, P., Mayor, F., Jr., and Murga, C. (2006) Curr. Biol. 16, 2042-2047
39. Cant, S. H., and Pitcher, J. A. (2005) Mol. Biol. Cell 16, 3088-3099
40. Ross, E. M., and Wilkie, T. M. (2000) Annu. Rev. Biochem. 69, 795-827
41. Bansal, G., Druey, K. M., and Xie, Z. (2007) Pharmacol. Ther. 116, 473-495
42. Xu, X., Zeng, W., Popov, S., Berman, D. M., Davignon, I., Yu, K., Yowe, D., Offermanns, S., Muallem, S., and Wilkie, T. M. (1999) J. Biol. Chem. 274, 3549-3556
43. Heximer, S. P., Watson, N., Linder, M. E., Blumer, K. J., and Hepler, J. R. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 14389-14393
44. Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., Gilman, A. G., and Worley, P. F. (1998) J. Neurosci. 18, 7178-7188
45. Heximer, S. P., Srinivasa, S. P., Bernstein, L. S., Bernard, J. L., Linder, M. E., Hepler, J. R., and Blumer, K. J. (1999) J. Biol. Chem. 274, 34253-34259
46. Scheschonka, A., Dessauer, C. W., Sinnarajah, S., Chidiac, P., Shi, C. S., and Kehrl, J. H. (2000) Mol. Pharmacol. 58, 719-728
47. Hao, J., Michalek, C., Zhang, W., Zhu, M., Xu, X., and Mende, U. (2006) J. Mol. Cell. Cardiol. 41, 51-61
48. Karakoula, A., Tovey, S. C., Brighton, P. J., and Willars, G. B. (2008) Eur. J. Pharmacol. 587, 16-24
49. Hepler, J. R., Berman, D. M., Gilman, A. G., and Kozasa, T. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 428-432
50. Anger, T., Zhang, W., and Mende, U. (2004) J. Biol. Chem. 279, 3906-3915
51. Kristelly, R., Earnest, B. T., Krishnamoorthy, L., and Tesmer, J. J. (2003) Acta Crystallogr. D Biol. Crystallogr. 59, 1859-1862
52. Heximer, S. P. (2004) Methods Enzymol. 390, 65-82
53. Lodowski, D. T., Barnhill, J. F., Pitcher, J. A., Capel, W. D., Lefkowitz, R. J., and Tesmer, J. J. (2003) Acta Crystallogr. D Biol. Crystallogr. 59, 936-939
54. Ehlert, F. J. (1988) Mol. Pharmacol. 33, 187-194
55. Chidiac, P., and Ross, E. M. (1999) J. Biol. Chem. 274, 19639-19643
56. Soundararajan, M., Willard, F. S., Kimple, A. J., Turnbull, A. P., Ball, L. J., Schoch, G. A., Gileadi, C., Fedorov, O. Y., Dowler, E. F., Higman, V. A., Hutsell, S. Q., Sundstrom, M., Doyle, D. A., and Siderovski, D. P. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 6457-6462
57. Roman, D. L., Talbot, J. N., Roof, R. A., Sunahara, R. K., Traynor, J. R., and Neubig, R. R. (2007) Mol. Pharmacol. 71, 169-175
58. Gu, S., He, J., Ho, W. T., Ramineni, S., Thal, D. M., Natesh, R., Tesmer, J. J., Hepler, J. R., and Heximer, S. P. (2007) J. Biol. Chem. 282, 33064-33075
59. Kreutz, B., Yao, D. M., Nance, M., Tanabe, S., Tesmer, J. J. G., and Kozasa, T. (2006) Biochemistry 45, 167-174
60. Natochin, M., McEntaffer, R. L., and Artemyev, N. O. (1998) J. Biol. Chem. 273, 6731-6735
61. Posner, B. A., Mukhopadhyay, S., Tesmer, J. J., Gilman, A. G., and Ross, E. M. (1999) Biochemistry 38, 7773-7779
62. Zeng, W., Xu, X., Popov, S., Mukhopadhyay, S., Chidiac, P., Swistok, J., Danho, W., Yagaloff, K. A., Fisher, S. L., Ross, E. M., Muallem, S., and Wilkie, T. M. (1998) J. Biol. Chem. 273, 34687-34690
63. Chen, C., Seow, K. T., Guo, K., Yaw, L. P., and Lin, S. C. (1999) J. Biol. Chem. 274, 19799-19806
64. Bernstein, L. S., Grillo, A. A., Loranger, S. S., and Linder, M. E. (2000) J. Biol. Chem. 275, 18520-18526
65. Bernstein, L. S., Ramineni, S., Hague, C., Cladman, W., Chidiac, P., Levey, A. I., and Hepler, J. R. (2004) J. Biol. Chem. 279, 21248-21256
66. Salim, S., Sinnarajah, S., Kehrl, J. H., and Dessauer, C. W. (2003) J. Biol. Chem. 278, 15842-15849
67. Schoeber, J. P., Topala, C. N., Wang, X., Diepens, R. J., Lambers, T. T., Hoenderop, J. G., and Bindels, R. J. (2006) J. Biol. Chem. 281, 29669-29674
68. Christopoulos, A., and Kenakin, T. (2002) Pharmacol. Rev. 54, 323-374
69. Conklin, B. R., Chabre, O., Wong, Y. H., Federman, A. D., and Bourne, H. R. (1992) J. Biol. Chem. 267, 31-34
70. Carman, C. V., Parent, J. L., Day, P. W., Pronin, A. N., Sternweis, P. M., Wedegaertner, P. B., Gilman, A. G., Benovic, J. L., and Kozasa, T. (1999) J. Biol. Chem. 274, 34483-34492
71. Arshavsky, V. Y., and Pugh, E. N., Jr. (1998) Neuron 20, 11-14
72. Arshavsky, V. Y., Lamb, T. D., and Pugh, E. N., Jr. (2002) Annu. Rev. Physiol. 64, 153-187
73. Cook, B., Bar-Yaacov, M., Cohen Ben-Ami, H., Goldstein, R. E., Paroush, Z., Selinger, Z., and Minke, B. (2000) Nat. Cell Biol. 2, 296-301
74. Ranganathan, R., Harris, G. L., Stevens, C. F., and Zuker, C. S. (1991) Nature 354, 230-232
75. Day, P. W., Carman, C. V., Sterne-Marr, R., Benovic, J. L., and Wedegaertner, P. B. (2003) Biochemistry 42, 9176-9184
76. Koch, W. J., Hawes, B. E., Inglese, J., Luttrell, L. M., and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 6193-6197
77. Koch, W. J., Rockman, H. A., Samama, P., Hamilton, R. A., Bond, R. A., Milano, C. A., and Lefkowitz, R. J. (1995) Science 268, 1350-1353