-
1
-
-
84861003638
-
Truth and consequences of sphingosine-1-phosphate lyase
-
Aguilar A., Saba J.D. Truth and consequences of sphingosine-1-phosphate lyase. Adv Biol Regul 2012, 52:17-30.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 17-30
-
-
Aguilar, A.1
Saba, J.D.2
-
2
-
-
80052243612
-
The possible involvement of glycogen synthase kinase-3 (GSK-3) in diabetes, cancer and central nervous system diseases
-
Amar S., Belmaker R.H., Agam G. The possible involvement of glycogen synthase kinase-3 (GSK-3) in diabetes, cancer and central nervous system diseases. Curr Pharm Des. 2011, 17:2264-2277.
-
(2011)
Curr Pharm Des.
, vol.17
, pp. 2264-2277
-
-
Amar, S.1
Belmaker, R.H.2
Agam, G.3
-
3
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas J.N., Moon R.T. WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 2013, 13:11-26.
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
4
-
-
12144266241
-
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition
-
Bachelder R.E., Yoon S.O., Franci C., de Herreros A.G., Mercurio A.M. Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition. JCell Biol 2005, 168:29-33.
-
(2005)
JCell Biol
, vol.168
, pp. 29-33
-
-
Bachelder, R.E.1
Yoon, S.O.2
Franci, C.3
de Herreros, A.G.4
Mercurio, A.M.5
-
5
-
-
84863229445
-
The intersection of genetic and chemical genomic screens identifies GSK-3alpha as a target in human acute myeloid leukemia
-
Banerji V., Frumm S.M., Ross K.N., Li L.S., Schinzel A.C., Hahn C.K., et al. The intersection of genetic and chemical genomic screens identifies GSK-3alpha as a target in human acute myeloid leukemia. JClin Invest 2012, 122:935-947.
-
(2012)
JClin Invest
, vol.122
, pp. 935-947
-
-
Banerji, V.1
Frumm, S.M.2
Ross, K.N.3
Li, L.S.4
Schinzel, A.C.5
Hahn, C.K.6
-
6
-
-
84865660375
-
Thoughts on Sec14-like nanoreactors and phosphoinositide signaling
-
Bankaitis V.A., Ile K.E., Nile A.H., Ren J., Ghosh R., Schaaf G. Thoughts on Sec14-like nanoreactors and phosphoinositide signaling. Adv Biol Regul 2012, 52:115-121.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 115-121
-
-
Bankaitis, V.A.1
Ile, K.E.2
Nile, A.H.3
Ren, J.4
Ghosh, R.5
Schaaf, G.6
-
7
-
-
84864571029
-
The pancreatic beta cell as a paradigm for advances in inositide research
-
Barker C.J., Berggren P.O. The pancreatic beta cell as a paradigm for advances in inositide research. Adv Biol Regul 2012, 52:361-368.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 361-368
-
-
Barker, C.J.1
Berggren, P.O.2
-
8
-
-
0028308702
-
Cyclin D1 protein expression and function in human breast cancer
-
Bartkova J., Lukas J., Müller H., Lützhøft D., Strauss M., Bartek J. Cyclin D1 protein expression and function in human breast cancer. Int J Cancer 1994, 57:353-361.
-
(1994)
Int J Cancer
, vol.57
, pp. 353-361
-
-
Bartkova, J.1
Lukas, J.2
Müller, H.3
Lützhøft, D.4
Strauss, M.5
Bartek, J.6
-
9
-
-
0035665719
-
The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation
-
Bax B., Carter P.S., Lewis C., Guy A.R., Bridges A., Tanner R., et al. The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation. Structure 2001, 9:1143-1152.
-
(2001)
Structure
, vol.9
, pp. 1143-1152
-
-
Bax, B.1
Carter, P.S.2
Lewis, C.3
Guy, A.R.4
Bridges, A.5
Tanner, R.6
-
10
-
-
39049122786
-
T-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism
-
Belkhiri A., Dar A.A., Zaika A., Kelley M., El-Rifai W. t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism. Cancer Res 2008, 68:395-403.
-
(2008)
Cancer Res
, vol.68
, pp. 395-403
-
-
Belkhiri, A.1
Dar, A.A.2
Zaika, A.3
Kelley, M.4
El-Rifai, W.5
-
11
-
-
0034680902
-
Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain
-
Bennecib M., Gong C.X., Grundke-Iqbal I., Iqbal K. Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain. FEBS Lett 2000, 485:87-93.
-
(2000)
FEBS Lett
, vol.485
, pp. 87-93
-
-
Bennecib, M.1
Gong, C.X.2
Grundke-Iqbal, I.3
Iqbal, K.4
-
12
-
-
79960044951
-
MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L
-
Bernt K.M., Zhu N., Sinha A.U., Vempati S., Faber J., Krivtsov A.V., et al. MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L. Cancer Cell 2011, 20:66-78.
-
(2011)
Cancer Cell
, vol.20
, pp. 66-78
-
-
Bernt, K.M.1
Zhu, N.2
Sinha, A.U.3
Vempati, S.4
Faber, J.5
Krivtsov, A.V.6
-
13
-
-
0035813212
-
Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta
-
Bijur G.N., Jope R.S. Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta. JBiol Chem 2001, 276:37436-37442.
-
(2001)
JBiol Chem
, vol.276
, pp. 37436-37442
-
-
Bijur, G.N.1
Jope, R.S.2
-
14
-
-
77953262873
-
Glycogen synthase kinase-3 and leukemia: restoring the balance
-
Birch N.W., Zeleznik-Le N.J. Glycogen synthase kinase-3 and leukemia: restoring the balance. Cancer Cell 2010, 17:529-531.
-
(2010)
Cancer Cell
, vol.17
, pp. 529-531
-
-
Birch, N.W.1
Zeleznik-Le, N.J.2
-
15
-
-
84874010025
-
Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies
-
Boultwood J., Yip B.H., Vuppusetty C., Pellagatti A., Wainscoat J.S. Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies. Adv Biol Regul 2013, 53:8-17.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 8-17
-
-
Boultwood, J.1
Yip, B.H.2
Vuppusetty, C.3
Pellagatti, A.4
Wainscoat, J.S.5
-
16
-
-
84864554955
-
PI3K keeps the balance between metabolism and cancer
-
Braccini L., Ciraolo E., Martini M., Pirali T., Germena G., Rolfo K., et al. PI3K keeps the balance between metabolism and cancer. Adv Biol Regul 2012, 52:389-405.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 389-405
-
-
Braccini, L.1
Ciraolo, E.2
Martini, M.3
Pirali, T.4
Germena, G.5
Rolfo, K.6
-
17
-
-
84874009500
-
Receptor tyrosine kinase signaling mechanisms: devolving TrkA responses with phosphoproteomics
-
Bradshaw R.A., Chalkley R.J., Biarc J., Burlingame A.L. Receptor tyrosine kinase signaling mechanisms: devolving TrkA responses with phosphoproteomics. Adv Biol Regul 2013, 53:87-96.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 87-96
-
-
Bradshaw, R.A.1
Chalkley, R.J.2
Biarc, J.3
Burlingame, A.L.4
-
18
-
-
84874006435
-
Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS)
-
Burke J.E., Williams R.L. Dynamic steps in receptor tyrosine kinase mediated activation of class IA phosphoinositide 3-kinases (PI3K) captured by H/D exchange (HDX-MS). Adv Biol Regul 2013, 53:97-110.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 97-110
-
-
Burke, J.E.1
Williams, R.L.2
-
19
-
-
34547589477
-
Modulation of PPAR activity via phosphorylation
-
Burns K.A., Vanden Heuvel J.P. Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta 2007, 1771:952-960.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 952-960
-
-
Burns, K.A.1
Vanden Heuvel, J.P.2
-
20
-
-
84865641259
-
Role of the C-terminal regulatory domain in the allosteric inhibition of PKB/Akt
-
Calleja V., Laguerre M., Larijani B. Role of the C-terminal regulatory domain in the allosteric inhibition of PKB/Akt. Adv Biol Regul 2012, 52:46-57.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 46-57
-
-
Calleja, V.1
Laguerre, M.2
Larijani, B.3
-
21
-
-
77955571571
-
Tuning mTORC1 activity for balanced self-renewal and differentiation
-
Carnevalli L.S., Trumpp A. Tuning mTORC1 activity for balanced self-renewal and differentiation. Dev Cell 2010, 19:187-188.
-
(2010)
Dev Cell
, vol.19
, pp. 187-188
-
-
Carnevalli, L.S.1
Trumpp, A.2
-
22
-
-
84865645434
-
Essential role of PIKE GTPases in neuronal protection against excitotoxic insults
-
Chan C.B., Chen Y., Liu X., Papale L., Escayg A., Mei L., et al. Essential role of PIKE GTPases in neuronal protection against excitotoxic insults. Adv Biol Regul 2012, 52:66-76.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 66-76
-
-
Chan, C.B.1
Chen, Y.2
Liu, X.3
Papale, L.4
Escayg, A.5
Mei, L.6
-
23
-
-
84874010286
-
Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment
-
Chappell W.H., Abrams S.L., Stadelman K.M., LaHair M.M., Franklin R.A., Cocco L., et al. Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment. Adv Biol Regul 2013, 53:146-155.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 146-155
-
-
Chappell, W.H.1
Abrams, S.L.2
Stadelman, K.M.3
LaHair, M.M.4
Franklin, R.A.5
Cocco, L.6
-
24
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen C., Liu Y., Liu R., Ikenoue T., Guan K.L., Liu Y., et al. TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. JExp Med 2008, 205:2397-2408.
-
(2008)
JExp Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Liu, Y.6
-
25
-
-
34848865728
-
Protein arginine-methyltransferase-dependent oncogenesis
-
Cheung N., Chan L.C., Thompson A., Cleary M.L., So C.W. Protein arginine-methyltransferase-dependent oncogenesis. Nat Cell Biol 2007, 9:1208-1215.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1208-1215
-
-
Cheung, N.1
Chan, L.C.2
Thompson, A.3
Cleary, M.L.4
So, C.W.5
-
26
-
-
33947678206
-
Thermogenic and metabolic antiobesity drugs: rationale and opportunities
-
Clapham J.C., Arch J.R. Thermogenic and metabolic antiobesity drugs: rationale and opportunities. Diabetes Obes Metab 2007, 9:259-275.
-
(2007)
Diabetes Obes Metab
, vol.9
, pp. 259-275
-
-
Clapham, J.C.1
Arch, J.R.2
-
27
-
-
84865655009
-
The activity, evolution and association of phosphatidylinositol 5-phosphate 4-kinases
-
Clarke J.H., Irvine R.F. The activity, evolution and association of phosphatidylinositol 5-phosphate 4-kinases. Adv Biol Regul 2012, 52:40-45.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 40-45
-
-
Clarke, J.H.1
Irvine, R.F.2
-
28
-
-
84861986053
-
Wnt/β-catenin signaling and disease
-
Clevers H., Nusse R. Wnt/β-catenin signaling and disease. Cell 2012, 149:1192-1205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
29
-
-
1642494586
-
Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event
-
Cole A., Frame S., Cohen P. Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event. Biochem J 2004, 377:249-255.
-
(2004)
Biochem J
, vol.377
, pp. 249-255
-
-
Cole, A.1
Frame, S.2
Cohen, P.3
-
30
-
-
0036730163
-
The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism
-
Collins E.C., Rabbitts T.H. The promiscuous MLL gene links chromosomal translocations to cellular differentiation and tumour tropism. Trends Mol Med 2002, 8:436-442.
-
(2002)
Trends Mol Med
, vol.8
, pp. 436-442
-
-
Collins, E.C.1
Rabbitts, T.H.2
-
31
-
-
2642550555
-
Essential role of Plzf in maintenance of spermatogonial stem cells
-
Costoya J.A., Hobbs R.M., Barna M., Cattoretti G., Manova K., Sukhwani M., et al. Essential role of Plzf in maintenance of spermatogonial stem cells. Nat Genet 2004, 36:653-659.
-
(2004)
Nat Genet
, vol.36
, pp. 653-659
-
-
Costoya, J.A.1
Hobbs, R.M.2
Barna, M.3
Cattoretti, G.4
Manova, K.5
Sukhwani, M.6
-
32
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross D.A., Alessi D.R., Cohen P., Andjelkovich M., Hemmings B.A. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995, 378:785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
33
-
-
51849147986
-
GSK-3beta inhibition: at the crossroad between Akt and mTOR constitutive activation to enhance cyclin D1 protein stability in mantle cell lymphoma
-
Dal Col J., Dolcetti R. GSK-3beta inhibition: at the crossroad between Akt and mTOR constitutive activation to enhance cyclin D1 protein stability in mantle cell lymphoma. Cell Cycle 2008, 7:2813-2816.
-
(2008)
Cell Cycle
, vol.7
, pp. 2813-2816
-
-
Dal Col, J.1
Dolcetti, R.2
-
34
-
-
28644444440
-
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
-
Davidson G., Wu W., Shen J., Bilic J., Fenger U., Stannek P., et al. Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 2005, 438:867-872.
-
(2005)
Nature
, vol.438
, pp. 867-872
-
-
Davidson, G.1
Wu, W.2
Shen, J.3
Bilic, J.4
Fenger, U.5
Stannek, P.6
-
35
-
-
84857975015
-
Metformin: multi-faceted protection against cancer
-
Del Barco S., Vazquez-Martin A., Cufi S., Oliveras-Ferraros C., Bosch-Barrera J., Joven J., et al. Metformin: multi-faceted protection against cancer. Oncotarget 2011, 2:896-917.
-
(2011)
Oncotarget
, vol.2
, pp. 896-917
-
-
Del Barco, S.1
Vazquez-Martin, A.2
Cufi, S.3
Oliveras-Ferraros, C.4
Bosch-Barrera, J.5
Joven, J.6
-
36
-
-
84872470005
-
Treatment of Alzheimer's disease with the GSK-3 inhibitor tideglusib: a pilot study
-
del Ser T., Steinwachs K.C., Gertz H.J., Andrés M.V., Gómez-Carrillo B., Medina M., et al. Treatment of Alzheimer's disease with the GSK-3 inhibitor tideglusib: a pilot study. Alzheimers Dis 2013, 33:205-215.
-
(2013)
Alzheimers Dis
, vol.33
, pp. 205-215
-
-
del Ser, T.1
Steinwachs, K.C.2
Gertz, H.J.3
Andrés, M.V.4
Gómez-Carrillo, B.5
Medina, M.6
-
37
-
-
0028960821
-
Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer
-
Dickson C., Fantl V., Gillett C., Brookes S., Bartek J., Smith R., et al. Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer. Cancer Lett 1995, 90:43-50.
-
(1995)
Cancer Lett
, vol.90
, pp. 43-50
-
-
Dickson, C.1
Fantl, V.2
Gillett, C.3
Brookes, S.4
Bartek, J.5
Smith, R.6
-
38
-
-
0032533225
-
Glycogen synthase kinase- 3beta regulates cyclin D1 proteolysis and subcellular localization
-
Diehl J.A., Cheng M., Roussel M.F., Sherr C.J. Glycogen synthase kinase- 3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998, 12:3499-3511.
-
(1998)
Genes Dev
, vol.12
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
39
-
-
34347350211
-
Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization
-
Ding Q., He X., Hsu J.M., Xia W., Chen C.T., Li L.Y., et al. Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization. Mol Cell Biol 2007, 27:4006-4017.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4006-4017
-
-
Ding, Q.1
He, X.2
Hsu, J.M.3
Xia, W.4
Chen, C.T.5
Li, L.Y.6
-
40
-
-
0037383322
-
GSK-3: tricks of the trade for a multi-tasking kinase
-
Doble B.W., Woodgett J.R. GSK-3: tricks of the trade for a multi-tasking kinase. JCell Sci 2003, 116:1175-1186.
-
(2003)
JCell Sci
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
41
-
-
34249311572
-
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines
-
Doble B.W., Patel S., Wood G.A., Kockeritz L.K., Woodgett J.R. Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev Cell 2007, 12:957-971.
-
(2007)
Dev Cell
, vol.12
, pp. 957-971
-
-
Doble, B.W.1
Patel, S.2
Wood, G.A.3
Kockeritz, L.K.4
Woodgett, J.R.5
-
42
-
-
16444380336
-
Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity
-
Dong J., Peng J., Zhang H., Mondesire W.H., Jian W., Mills G.B., et al. Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity. Cancer Res 2005, 65:1961-1972.
-
(2005)
Cancer Res
, vol.65
, pp. 1961-1972
-
-
Dong, J.1
Peng, J.2
Zhang, H.3
Mondesire, W.H.4
Jian, W.5
Mills, G.B.6
-
43
-
-
69749125286
-
PLZF is a regulator of homeostatic and cytokine-induced myeloid development
-
Doulatov S., Notta F., Rice K.L., Howell L., Zelent A., Licht J.D., et al. PLZF is a regulator of homeostatic and cytokine-induced myeloid development. Genes Dev 2009, 23:2076-2087.
-
(2009)
Genes Dev
, vol.23
, pp. 2076-2087
-
-
Doulatov, S.1
Notta, F.2
Rice, K.L.3
Howell, L.4
Zelent, A.5
Licht, J.D.6
-
44
-
-
84874002628
-
SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts
-
Elong Edimo W., Vanderwinden J.M., Erneux C. SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts. Adv Biol Regul 2013, 53:28-37.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 28-37
-
-
Elong Edimo, W.1
Vanderwinden, J.M.2
Erneux, C.3
-
45
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi N., Rylatt D.B., Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 1980, 107:519-527.
-
(1980)
Eur J Biochem
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
46
-
-
0041856097
-
Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways
-
Espinosa L., Inglés-Esteve J., Aguilera C., Bigas A. Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways. JBiol Chem 2003, 278:32227-32235.
-
(2003)
JBiol Chem
, vol.278
, pp. 32227-32235
-
-
Espinosa, L.1
Inglés-Esteve, J.2
Aguilera, C.3
Bigas, A.4
-
47
-
-
21344463325
-
Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis
-
Farago M., Dominguez I., Landesman-Bollag E., Xu X., Rosner A., Cardiff R.D., et al. Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis. Cancer Res 2005, 65:5792-5801.
-
(2005)
Cancer Res
, vol.65
, pp. 5792-5801
-
-
Farago, M.1
Dominguez, I.2
Landesman-Bollag, E.3
Xu, X.4
Rosner, A.5
Cardiff, R.D.6
-
48
-
-
0037013313
-
Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin
-
Ferkey D.M., Kimelman D. Glycogen synthase kinase-3 beta mutagenesis identifies a common binding domain for GBP and Axin. JBiol Chem 2002, 277:16147-16152.
-
(2002)
JBiol Chem
, vol.277
, pp. 16147-16152
-
-
Ferkey, D.M.1
Kimelman, D.2
-
49
-
-
84865653877
-
Revisiting nuclear phospholipase C signalling in MDS
-
Follo M.Y., Faenza I., Fiume R., Ramazzotti G., McCubrey J.A., Martelli A.M., et al. Revisiting nuclear phospholipase C signalling in MDS. Adv Biol Regul 2012, 52:2-6.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 2-6
-
-
Follo, M.Y.1
Faenza, I.2
Fiume, R.3
Ramazzotti, G.4
McCubrey, J.A.5
Martelli, A.M.6
-
50
-
-
84874007797
-
Nuclear phospholipase C beta1 signaling, epigenetics and treatments in MDS
-
Follo M.Y., Marmiroli S., Faenza I., Fiume R., Ramazzotti G., Martelli A.M., et al. Nuclear phospholipase C beta1 signaling, epigenetics and treatments in MDS. Adv Biol Regul 2013, 53:2-7.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 2-7
-
-
Follo, M.Y.1
Marmiroli, S.2
Faenza, I.3
Fiume, R.4
Ramazzotti, G.5
Martelli, A.M.6
-
51
-
-
0037172661
-
Glycogen synthase kinase-3beta modulates notch signaling and stability
-
Foltz D.R., Santiago M.C., Berechid B.E., Nye J.S. Glycogen synthase kinase-3beta modulates notch signaling and stability. Curr Biol 2002, 12:1006-1011.
-
(2002)
Curr Biol
, vol.12
, pp. 1006-1011
-
-
Foltz, D.R.1
Santiago, M.C.2
Berechid, B.E.3
Nye, J.S.4
-
52
-
-
0037113982
-
The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP
-
Franca-Koh J., Yeo M., Fraser E., Young N., Dale T.C. The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP. JBiol Chem 2002, 277:43844-43848.
-
(2002)
JBiol Chem
, vol.277
, pp. 43844-43848
-
-
Franca-Koh, J.1
Yeo, M.2
Fraser, E.3
Young, N.4
Dale, T.C.5
-
53
-
-
80051652238
-
Overexpression of glycogen synthase kinase-3 in ovarian carcinoma cells with acquired paclitaxel resistance
-
Fu Y., Hu D., Qiu J., Xie X., Ye F., Lu W.G. Overexpression of glycogen synthase kinase-3 in ovarian carcinoma cells with acquired paclitaxel resistance. Internl J Gyn Cancer 2011, 21:439-444.
-
(2011)
Internl J Gyn Cancer
, vol.21
, pp. 439-444
-
-
Fu, Y.1
Hu, D.2
Qiu, J.3
Xie, X.4
Ye, F.5
Lu, W.G.6
-
54
-
-
58049196780
-
MTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization
-
Gan B., Sahin E., Jiang S., Sanchez-Aguilera A., Scott K.L., Chin L., et al. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proc Natl Acad Sci USA 2008, 105:19384-19389.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19384-19389
-
-
Gan, B.1
Sahin, E.2
Jiang, S.3
Sanchez-Aguilera, A.4
Scott, K.L.5
Chin, L.6
-
55
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
Gan B., Hu J., Jiang S., Liu Y., Sahin E., Zhuang L., et al. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 2010, 468:701-704.
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
Hu, J.2
Jiang, S.3
Liu, Y.4
Sahin, E.5
Zhuang, L.6
-
56
-
-
84860520259
-
GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease
-
Gao C., Holscher C., Liu Y., Li L. GSK3: a key target for the development of novel treatments for type 2 diabetes mellitus and Alzheimer disease. Rev Neurosciences 2012, 23:1-11.
-
(2012)
Rev Neurosciences
, vol.23
, pp. 1-11
-
-
Gao, C.1
Holscher, C.2
Liu, Y.3
Li, L.4
-
57
-
-
33947228487
-
RTP801 is a novel retinoic acid-responsive gene associated with myeloid differentiation
-
Gery S., Park D.J., Vuong P.T., Virk R.K., Muller C.I., Hofmann W.K., et al. RTP801 is a novel retinoic acid-responsive gene associated with myeloid differentiation. Exp Hematol 2007, 35:572-578.
-
(2007)
Exp Hematol
, vol.35
, pp. 572-578
-
-
Gery, S.1
Park, D.J.2
Vuong, P.T.3
Virk, R.K.4
Muller, C.I.5
Hofmann, W.K.6
-
58
-
-
79954520404
-
The mechanism of contribution of integrin linked kinase (ILK) to epithelial mesenchymal transition
-
Gil D., Ciolczyk-Wierzbicka D., Dulinska-Litewka J., Zwawa K., McCubrey J.A., Laidler P. The mechanism of contribution of integrin linked kinase (ILK) to epithelial mesenchymal transition. Adv Enzym Regul 2011, 51:195-207.
-
(2011)
Adv Enzym Regul
, vol.51
, pp. 195-207
-
-
Gil, D.1
Ciolczyk-Wierzbicka, D.2
Dulinska-Litewka, J.3
Zwawa, K.4
McCubrey, J.A.5
Laidler, P.6
-
59
-
-
0028331092
-
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
-
Gillett C., Fantl V., Smith R., Fisher C., Bartek J., Dickson C., et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994, 54:1812-1817.
-
(1994)
Cancer Res
, vol.54
, pp. 1812-1817
-
-
Gillett, C.1
Fantl, V.2
Smith, R.3
Fisher, C.4
Bartek, J.5
Dickson, C.6
-
60
-
-
84856757946
-
AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications
-
Grimaldi C., Chiarini F., Tabellini G., Ricci F., Tazzari P.L., Battistelli M., et al. AMP-dependent kinase/mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications. Leukemia 2012, 26:91-100.
-
(2012)
Leukemia
, vol.26
, pp. 91-100
-
-
Grimaldi, C.1
Chiarini, F.2
Tabellini, G.3
Ricci, F.4
Tazzari, P.L.5
Battistelli, M.6
-
61
-
-
84862005911
-
GSK3 is a regulator of RAR-mediated differentiation
-
Gupta K., Gulen F., Sun L., Aguilera R., Chakrabarti A., Kiselar J., et al. GSK3 is a regulator of RAR-mediated differentiation. Leukemia 2012, 26:1277-1285.
-
(2012)
Leukemia
, vol.26
, pp. 1277-1285
-
-
Gupta, K.1
Gulen, F.2
Sun, L.3
Aguilera, R.4
Chakrabarti, A.5
Kiselar, J.6
-
62
-
-
84862995649
-
Mechanism of activation of AMPK and upregulation of OGG1 by rapamycin in cancer cells
-
Habib S.L. Mechanism of activation of AMPK and upregulation of OGG1 by rapamycin in cancer cells. Oncotarget 2011, 2:958-959.
-
(2011)
Oncotarget
, vol.2
, pp. 958-959
-
-
Habib, S.L.1
-
63
-
-
84862888714
-
Glycogen synthase kinase 3-beta phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization
-
Han X., Ju J.H., Shin I. Glycogen synthase kinase 3-beta phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization. Biochem Biophys Res Commun 2012, 423:282-288.
-
(2012)
Biochem Biophys Res Commun
, vol.423
, pp. 282-288
-
-
Han, X.1
Ju, J.H.2
Shin, I.3
-
65
-
-
84874002204
-
Structure-function relationships of autotaxin, a secreted lysophospholipase D
-
Hausmann J., Perrakis A., Moolenaar W.H. Structure-function relationships of autotaxin, a secreted lysophospholipase D. Adv Biol Regul 2013, 53:112-117.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 112-117
-
-
Hausmann, J.1
Perrakis, A.2
Moolenaar, W.H.3
-
66
-
-
0033638004
-
Two critical hits for promyelocytic leukemia
-
He L.Z., Bhaumik M., Tribioli C., Rego E.M., Ivins S., Zelent A., et al. Two critical hits for promyelocytic leukemia. Mol Cell 2000, 6:1131-1141.
-
(2000)
Mol Cell
, vol.6
, pp. 1131-1141
-
-
He, L.Z.1
Bhaumik, M.2
Tribioli, C.3
Rego, E.M.4
Ivins, S.5
Zelent, A.6
-
67
-
-
84860149268
-
Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle
-
Hnia K., Kretz C., Amoasii L., Bohm J., Liu X., Messaddeq N., et al. Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle. Adv Biol Regul 2012, 52:98-107.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 98-107
-
-
Hnia, K.1
Kretz, C.2
Amoasii, L.3
Bohm, J.4
Liu, X.5
Messaddeq, N.6
-
68
-
-
77955329636
-
Plzf regulates germline progenitor self-renewal by opposing mTORC1
-
Hobbs R.M., Seandel M., Falciatori I., Rafii S., Pandolfi P.P. Plzf regulates germline progenitor self-renewal by opposing mTORC1. Cell 2010, 142:468-479.
-
(2010)
Cell
, vol.142
, pp. 468-479
-
-
Hobbs, R.M.1
Seandel, M.2
Falciatori, I.3
Rafii, S.4
Pandolfi, P.P.5
-
69
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich K.P., Luo J., Rubie E.A., Tsao M.S., Jin O., Woodgett J.R. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 2000, 406:86-90.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
70
-
-
72849126360
-
Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice
-
Huang J., Zhang Y., Bersenev A., O'Brien W.T., Tong W., Emerson S.G., et al. Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice. JClin Invest 2009, 119:3519-3529.
-
(2009)
JClin Invest
, vol.119
, pp. 3519-3529
-
-
Huang, J.1
Zhang, Y.2
Bersenev, A.3
O'Brien, W.T.4
Tong, W.5
Emerson, S.G.6
-
71
-
-
84870866912
-
Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways
-
Huang J., Nguyen-McCarty M., Hexner E.O., Danet-Desnoyers G., Klein P.S. Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways. Nat Med 2012, 18:1778-1785.
-
(2012)
Nat Med
, vol.18
, pp. 1778-1785
-
-
Huang, J.1
Nguyen-McCarty, M.2
Hexner, E.O.3
Danet-Desnoyers, G.4
Klein, P.S.5
-
72
-
-
0027475421
-
Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation
-
Hughes K., Nikolakaki E., Plyte S.E., Totty N.F., Woodgett J.R. Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation. EMBO J 1993, 12:803-808.
-
(1993)
EMBO J
, vol.12
, pp. 803-808
-
-
Hughes, K.1
Nikolakaki, E.2
Plyte, S.E.3
Totty, N.F.4
Woodgett, J.R.5
-
73
-
-
84878559365
-
On the regulation of protein phosphatase 2A and its role in controlling entry into and exit from mitosis
-
Hunt T. On the regulation of protein phosphatase 2A and its role in controlling entry into and exit from mitosis. Adv Biol Regul 2013, 2013(53):173-178.
-
(2013)
Adv Biol Regul
, vol.2013
, Issue.53
, pp. 173-178
-
-
Hunt, T.1
-
74
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
-
Ikeda S., Kishida S., Yamamoto H., Murai H., Koyama S., Kikuchi A. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J 1998, 17:1371-1384.
-
(1998)
EMBO J
, vol.17
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
75
-
-
33748153690
-
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
-
Inoki K., Ouyang H., Zhu T., Lindvall C., Wang Y., Zhang X., et al. TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 2006, 126:955-968.
-
(2006)
Cell
, vol.126
, pp. 955-968
-
-
Inoki, K.1
Ouyang, H.2
Zhu, T.3
Lindvall, C.4
Wang, Y.5
Zhang, X.6
-
76
-
-
84862908818
-
AMPK and mTOR in cellular energy homeostasis and drug targets
-
Inoki K., Kim J., Guan K.L. AMPK and mTOR in cellular energy homeostasis and drug targets. Annu Rev Pharmacol Toxicol 2012, 52:381-400.
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 381-400
-
-
Inoki, K.1
Kim, J.2
Guan, K.L.3
-
77
-
-
84868632060
-
APML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
-
Ito K., Carracedo A., Weiss D., Arai F., Ala U., Avigan D.E., et al. APML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med 2012, 18:1350-1358.
-
(2012)
Nat Med
, vol.18
, pp. 1350-1358
-
-
Ito, K.1
Carracedo, A.2
Weiss, D.3
Arai, F.4
Ala, U.5
Avigan, D.E.6
-
78
-
-
84874001481
-
Phospholipase C-1 involved in brain disorders
-
Jang H.J., Yang Y.R., Kim J.K., Choi J.H., Seo Y.K., Lee Y.H., et al. Phospholipase C-1 involved in brain disorders. Adv Biol Regul 2013, 53:51-62.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 51-62
-
-
Jang, H.J.1
Yang, Y.R.2
Kim, J.K.3
Choi, J.H.4
Seo, Y.K.5
Lee, Y.H.6
-
79
-
-
38049105637
-
Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin
-
Jeannet G., Scheller M., Scarpellino L., Duboux S., Gardiol N., Back J., et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood 2008, 111:142-149.
-
(2008)
Blood
, vol.111
, pp. 142-149
-
-
Jeannet, G.1
Scheller, M.2
Scarpellino, L.3
Duboux, S.4
Gardiol, N.5
Back, J.6
-
80
-
-
84878612879
-
Deconstructing mTOR complexes in regulation of Glioblastoma Multiforme and its stem cells
-
Jhanwar-Uniyal M., Jeevan D., Neil J., Shannon C., Albert L., Murali R. Deconstructing mTOR complexes in regulation of Glioblastoma Multiforme and its stem cells. Adv Biol Regul 2013, 53:202-210.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 202-210
-
-
Jhanwar-Uniyal, M.1
Jeevan, D.2
Neil, J.3
Shannon, C.4
Albert, L.5
Murali, R.6
-
81
-
-
58549108259
-
Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction
-
Jin Y.H., Kim H., Ki H., Yang I., Yang N., Lee K.Y., et al. Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction. Biochim Biophys Acta 2009, 1793:290-299.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 290-299
-
-
Jin, Y.H.1
Kim, H.2
Ki, H.3
Yang, I.4
Yang, N.5
Lee, K.Y.6
-
82
-
-
62849118806
-
Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta
-
Jin Y.H., Kim H., Oh M., Ki H., Kim K. Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta. Mol Cells 2009, 27:15-19.
-
(2009)
Mol Cells
, vol.27
, pp. 15-19
-
-
Jin, Y.H.1
Kim, H.2
Oh, M.3
Ki, H.4
Kim, K.5
-
83
-
-
72449146342
-
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice
-
Kaidanovich-Beilin O., Lipina T.V., Takao K., van Eede M., Hattori S., Laliberté C., et al. Abnormalities in brain structure and behavior in GSK-3alpha mutant mice. Mol Brain 2009, 2:35.
-
(2009)
Mol Brain
, vol.2
, pp. 35
-
-
Kaidanovich-Beilin, O.1
Lipina, T.V.2
Takao, K.3
van Eede, M.4
Hattori, S.5
Laliberté, C.6
-
84
-
-
84865637570
-
Regulation and functions of the lipid kinase PIP5K g661 at synapses
-
Kanaho Y., Unoki T. Regulation and functions of the lipid kinase PIP5K g661 at synapses. Adv Biol Regul 2012, 52:59-65.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 59-65
-
-
Kanaho, Y.1
Unoki, T.2
-
85
-
-
68249104457
-
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase
-
Katiyar S., Liu E., Knutzen C.A., Lang E.S., Lombardo C.R., Sankar S., et al. REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase. EMBO Rep 2009, 10:866-872.
-
(2009)
EMBO Rep
, vol.10
, pp. 866-872
-
-
Katiyar, S.1
Liu, E.2
Knutzen, C.A.3
Lang, E.S.4
Lombardo, C.R.5
Sankar, S.6
-
86
-
-
84863314567
-
GSK-3 inhibition invitro and invivo enhances antitumor effect of sorafenib in renal cell carcinoma (RCC)
-
Kawazoe H., Bilim V.N., Ugolkov A.V., Yuuki K., Naito S., Nagaoka A., et al. GSK-3 inhibition invitro and invivo enhances antitumor effect of sorafenib in renal cell carcinoma (RCC). Biochem Biophys Res Commun 2012, 423:490-495.
-
(2012)
Biochem Biophys Res Commun
, vol.423
, pp. 490-495
-
-
Kawazoe, H.1
Bilim, V.N.2
Ugolkov, A.V.3
Yuuki, K.4
Naito, S.5
Nagaoka, A.6
-
87
-
-
84878608998
-
PtdIns5P and Pin1 in oxidative stress signaling
-
Keune W.J., Jones D.R., Divecha N. PtdIns5P and Pin1 in oxidative stress signaling. Adv Biol Regul 2013, 53:179-189.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 179-189
-
-
Keune, W.J.1
Jones, D.R.2
Divecha, N.3
-
88
-
-
84865661360
-
Loss of Akt1 evokes epithelial-mesenchymal transition by autocrine regulation of transforming growth factor-1
-
Kim E.K., Yun S.J., Ha J.M., Kim Y.W., Jin I.H., Woo D.H., et al. Loss of Akt1 evokes epithelial-mesenchymal transition by autocrine regulation of transforming growth factor-1. Adv Biol Regul 2012, 52:88-96.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 88-96
-
-
Kim, E.K.1
Yun, S.J.2
Ha, J.M.3
Kim, Y.W.4
Jin, I.H.5
Woo, D.H.6
-
89
-
-
68249125941
-
Sufu recruits GSK3beta for efficient processing of Gli3
-
Kise Y., Morinaka A., Teglund S., Miki H. Sufu recruits GSK3beta for efficient processing of Gli3. Biochem Biophys Res Commun 2009, 387:569-574.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, pp. 569-574
-
-
Kise, Y.1
Morinaka, A.2
Teglund, S.3
Miki, H.4
-
90
-
-
0033194243
-
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
Kogerman P., Grimm T., Kogerman L., Krause D., Undén A.B., Sandstedt B., et al. Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat Cell Biol 1999, 1:312-319.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
Grimm, T.2
Kogerman, L.3
Krause, D.4
Undén, A.B.5
Sandstedt, B.6
-
91
-
-
33746498580
-
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
Krivtsov A.V., Twomey D., Feng Z., Stubbs M.C., Wang Y., Faber J., et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 2006, 442:818-822.
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
Stubbs, M.C.4
Wang, Y.5
Faber, J.6
-
92
-
-
0032126633
-
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
-
Kroon E., Krosl J., Thorsteinsdottir U., Baban S., Buchberg A.M., Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 1998, 17:3714-3725.
-
(1998)
EMBO J
, vol.17
, pp. 3714-3725
-
-
Kroon, E.1
Krosl, J.2
Thorsteinsdottir, U.3
Baban, S.4
Buchberg, A.M.5
Sauvageau, G.6
-
93
-
-
84863863498
-
Distinct inactivation of PI3K signalling by PTEN and 5-phosphatases
-
Leslie N.R., Dixon M.J., Schenning M., Gray A., Batty I.H. Distinct inactivation of PI3K signalling by PTEN and 5-phosphatases. Adv Biol Regul 2012, 52:205-213.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 205-213
-
-
Leslie, N.R.1
Dixon, M.J.2
Schenning, M.3
Gray, A.4
Batty, I.H.5
-
94
-
-
0032955426
-
Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase
-
Lesort M., Jope R.S., Johnson G.V. Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase. JNeurochem 1999, 72:576-584.
-
(1999)
JNeurochem
, vol.72
, pp. 576-584
-
-
Lesort, M.1
Jope, R.S.2
Johnson, G.V.3
-
95
-
-
0034636153
-
Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression
-
Lin S.Y., Xia W., Wang J.C., Kwong K.Y., Spohn B., Wen Y., et al. Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci USA 2000, 97:4262-4266.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4262-4266
-
-
Lin, S.Y.1
Xia, W.2
Wang, J.C.3
Kwong, K.Y.4
Spohn, B.5
Wen, Y.6
-
96
-
-
7744227096
-
Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis
-
Linseman D.A., Butts B.D., Precht T.A., Phelps R.A., Le S.S., Laessig T.A., et al. Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis. JNeuroscience 2004, 24:9993-10002.
-
(2004)
JNeuroscience
, vol.24
, pp. 9993-10002
-
-
Linseman, D.A.1
Butts, B.D.2
Precht, T.A.3
Phelps, R.A.4
Le, S.S.5
Laessig, T.A.6
-
97
-
-
34250615440
-
NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders
-
Luna-Medina R., Cortes-Canteli M., Sanchez-Galiano S., Morales-Garcia J.A., Martinez A., Santos A., et al. NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders. JNeurosci 2007, 27:5766-5776.
-
(2007)
JNeurosci
, vol.27
, pp. 5766-5776
-
-
Luna-Medina, R.1
Cortes-Canteli, M.2
Sanchez-Galiano, S.3
Morales-Garcia, J.A.4
Martinez, A.5
Santos, A.6
-
98
-
-
57349143530
-
Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy
-
Luo J. Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. Cancer Lett 2009, 273:194-200.
-
(2009)
Cancer Lett
, vol.273
, pp. 194-200
-
-
Luo, J.1
-
99
-
-
34548017628
-
The role of glycogen synthase kinase 3beta in the transformation of epidermal cells
-
Ma C., Wang J., Gao Y., Gao T.W., Chen G., Bower K.A., et al. The role of glycogen synthase kinase 3beta in the transformation of epidermal cells. Cancer Res 2007, 67:7756-7764.
-
(2007)
Cancer Res
, vol.67
, pp. 7756-7764
-
-
Ma, C.1
Wang, J.2
Gao, Y.3
Gao, T.W.4
Chen, G.5
Bower, K.A.6
-
100
-
-
34548841091
-
Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism
-
MacAulay K., Doble B.W., Patel S., Hansotia T., Sinclair E.M., Drucker D.J., et al. Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metab 2007, 6:329-337.
-
(2007)
Cell Metab
, vol.6
, pp. 329-337
-
-
MacAulay, K.1
Doble, B.W.2
Patel, S.3
Hansotia, T.4
Sinclair, E.M.5
Drucker, D.J.6
-
101
-
-
34547490078
-
PTEN is destabilized by phosphorylation on Thr366
-
Maccario H., Perera N.M., Davidson L., Downes C.P., Leslie N.R. PTEN is destabilized by phosphorylation on Thr366. Biochem J 2007, 405:439-444.
-
(2007)
Biochem J
, vol.405
, pp. 439-444
-
-
Maccario, H.1
Perera, N.M.2
Davidson, L.3
Downes, C.P.4
Leslie, N.R.5
-
102
-
-
67650230896
-
Wnt/beta-catenin signaling: components, mechanisms, and diseases
-
MacDonald B.T., Tamai K., He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 2009, 17:9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
103
-
-
62549160065
-
Dysregulated gene expression networks in human acute myelogenous leukemia stem cells
-
Majeti R., Becker M.W., Tian Q., Lee T.L., Yan X., Liu R., et al. Dysregulated gene expression networks in human acute myelogenous leukemia stem cells. Proc Natl Acad Sci USA 2009, 106:3396-3401.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 3396-3401
-
-
Majeti, R.1
Becker, M.W.2
Tian, Q.3
Lee, T.L.4
Yan, X.5
Liu, R.6
-
104
-
-
34249061491
-
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
-
Major M.B., Camp N.D., Berndt J.D., Yi X., Goldenberg S.J., Hubbert C., et al. Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling. Science 2007, 316:1043-1046.
-
(2007)
Science
, vol.316
, pp. 1043-1046
-
-
Major, M.B.1
Camp, N.D.2
Berndt, J.D.3
Yi, X.4
Goldenberg, S.J.5
Hubbert, C.6
-
105
-
-
84857986934
-
Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms
-
Marchand B., Tremblay I., Cagnol S., Boucher M.J. Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms. Carcinogenesis 2012, 33:529-537.
-
(2012)
Carcinogenesis
, vol.33
, pp. 529-537
-
-
Marchand, B.1
Tremblay, I.2
Cagnol, S.3
Boucher, M.J.4
-
106
-
-
84862558416
-
Targeting the liver Kinase B1/AMP-dependent kinase pathway as a therapeutic strategy for hematological malignancies
-
Martelli A.M., Chiarini F., Evangelisti C., Ognibene A., Bressanin D., Billi A.M., et al. Targeting the liver Kinase B1/AMP-dependent kinase pathway as a therapeutic strategy for hematological malignancies. Expert Opin Therap Targets 2012, 6:729-742.
-
(2012)
Expert Opin Therap Targets
, vol.6
, pp. 729-742
-
-
Martelli, A.M.1
Chiarini, F.2
Evangelisti, C.3
Ognibene, A.4
Bressanin, D.5
Billi, A.M.6
-
107
-
-
84865634004
-
PI3K/AKT/mTORC1 and MEK/ERK signaling in T-cell acute lymphoblastic leukemia: new options for targeted therapy
-
Martelli A.M., Tabellini G., Ricci F., Evangelisti C., Chiarini F., Bortul R., et al. PI3K/AKT/mTORC1 and MEK/ERK signaling in T-cell acute lymphoblastic leukemia: new options for targeted therapy. Adv Biol Regul 2012, 52:214-227.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 214-227
-
-
Martelli, A.M.1
Tabellini, G.2
Ricci, F.3
Evangelisti, C.4
Chiarini, F.5
Bortul, R.6
-
108
-
-
79954544680
-
Targeting the cancer initiating cells: the Achilles' heel of cancer
-
McCubrey J.A., Chappell W.H., Abrams S.L., Franklin R.A., Long J.M., Sattler J.A., et al. Targeting the cancer initiating cells: the Achilles' heel of cancer. Adv Enzym Regul 2011, 51:152-162.
-
(2011)
Adv Enzym Regul
, vol.51
, pp. 152-162
-
-
McCubrey, J.A.1
Chappell, W.H.2
Abrams, S.L.3
Franklin, R.A.4
Long, J.M.5
Sattler, J.A.6
-
109
-
-
84868628069
-
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response
-
McCubrey J.A., Steelman L.S., Chappell W.H., Abrams S.L., Montalto G., Cervello M., et al. Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response. Oncotarget 2012, 3:954-987.
-
(2012)
Oncotarget
, vol.3
, pp. 954-987
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
Abrams, S.L.4
Montalto, G.5
Cervello, M.6
-
110
-
-
84871491627
-
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance
-
McCubrey J.A., Steelman L.S., Chappell W.H., Abrams S.L., Franklin R.A., Montalto G., et al. Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance. Oncotarget 2012, 3:1068-1111.
-
(2012)
Oncotarget
, vol.3
, pp. 1068-1111
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
Abrams, S.L.4
Franklin, R.A.5
Montalto, G.6
-
111
-
-
84865622421
-
Novel approaches to target cancer initiating cells-Eliminating the root of the cancer
-
McCubrey J.A., Abrams S.L., Umezawa K., Cocco L., Martelli A.M., Franklin R.A., et al. Novel approaches to target cancer initiating cells-Eliminating the root of the cancer. Adv Biol Regul 2012, 52:249-264.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 249-264
-
-
McCubrey, J.A.1
Abrams, S.L.2
Umezawa, K.3
Cocco, L.4
Martelli, A.M.5
Franklin, R.A.6
-
112
-
-
84891841884
-
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
-
Jun 19
-
McCubrey J.A., Steelman L.S., Bertrand F.E., Davis N.M., Abrams S.L., Montalto G., et al. Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention. Leukemia 2013 Jun 19, 10.1038/leu.2013.184.
-
(2013)
Leukemia
-
-
McCubrey, J.A.1
Steelman, L.S.2
Bertrand, F.E.3
Davis, N.M.4
Abrams, S.L.5
Montalto, G.6
-
113
-
-
77953312514
-
Glycogen synthase kinase 3 beta: can it be a target for oral cancer?
-
Mishra R. Glycogen synthase kinase 3 beta: can it be a target for oral cancer?. Mo Cancer 2010, 9:144.
-
(2010)
Mo Cancer
, vol.9
, pp. 144
-
-
Mishra, R.1
-
114
-
-
48449094498
-
AMPK and PPARdelta agonists are exercise mimetics
-
Narkar V.A., Downes M., Yu R.T., Embler E., Wang Y.X., Banayo E., et al. AMPK and PPARdelta agonists are exercise mimetics. Cell 2008, 134:405-415.
-
(2008)
Cell
, vol.134
, pp. 405-415
-
-
Narkar, V.A.1
Downes, M.2
Yu, R.T.3
Embler, E.4
Wang, Y.X.5
Banayo, E.6
-
115
-
-
16844374033
-
Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells
-
Ougolkov A.V., Fernandez-Zapico M.E., Savoy D.N., Urrutia R.A., Billadeau D.D. Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Res 2005, 65:2076-2081.
-
(2005)
Cancer Res
, vol.65
, pp. 2076-2081
-
-
Ougolkov, A.V.1
Fernandez-Zapico, M.E.2
Savoy, D.N.3
Urrutia, R.A.4
Billadeau, D.D.5
-
116
-
-
54549120290
-
Glycogen synthase kinase-3 and cancer: good cop, bad cop?
-
Patel S., Woodgett J.R. Glycogen synthase kinase-3 and cancer: good cop, bad cop?. Cancer Cell 2008, 14:351-353.
-
(2008)
Cancer Cell
, vol.14
, pp. 351-353
-
-
Patel, S.1
Woodgett, J.R.2
-
117
-
-
84874013459
-
Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) controls survival, proliferation and cytokine production in mouse peripheral T cells
-
Pouillon V., Marechal Y., Frippiat C., Erneux C., Schurmans S. Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) controls survival, proliferation and cytokine production in mouse peripheral T cells. Adv Biol Regul 2013, 53:39-50.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 39-50
-
-
Pouillon, V.1
Marechal, Y.2
Frippiat, C.3
Erneux, C.4
Schurmans, S.5
-
118
-
-
84865657973
-
Phospholipase C signaling and calcium influx
-
Putney J.W., Tomita T. Phospholipase C signaling and calcium influx. Adv Biol Regul 2012, 52:152-164.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 152-164
-
-
Putney, J.W.1
Tomita, T.2
-
119
-
-
84865654249
-
Targeting sphingosine kinase 1 in cancer
-
Pyne N.J., Tonelli F., Lim K.G., Long J., Edwards J., Pyne S. Targeting sphingosine kinase 1 in cancer. Adv Biol Regul 2012, 52:31-38.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 31-38
-
-
Pyne, N.J.1
Tonelli, F.2
Lim, K.G.3
Long, J.4
Edwards, J.5
Pyne, S.6
-
120
-
-
84865654433
-
Phosphoinositides signalling in cancer: focus on PI3K and PLC
-
Raimondi C., Falasca M. Phosphoinositides signalling in cancer: focus on PI3K and PLC. Adv Biol Regul 2012, 52:166-182.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 166-182
-
-
Raimondi, C.1
Falasca, M.2
-
121
-
-
84878596429
-
IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia
-
Ribeiro D., Melao A., Barata J.T. IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia. Adv Biol Regul 2013, 53:211-222.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 211-222
-
-
Ribeiro, D.1
Melao, A.2
Barata, J.T.3
-
122
-
-
34147167683
-
Hox deregulation in acute myeloid leukemia
-
Rice K.L., Licht J.D. Hox deregulation in acute myeloid leukemia. Clin Invest 2007, 117:865-868.
-
(2007)
Clin Invest
, vol.117
, pp. 865-868
-
-
Rice, K.L.1
Licht, J.D.2
-
123
-
-
39149086121
-
Stems cells and the pathways to aging and cancer
-
Rossi D.J., Jamieson C.H., Weissman I.L. Stems cells and the pathways to aging and cancer. Cell 2008, 132:681-696.
-
(2008)
Cell
, vol.132
, pp. 681-696
-
-
Rossi, D.J.1
Jamieson, C.H.2
Weissman, I.L.3
-
124
-
-
0037155824
-
Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation
-
Rossig L., Badorff C., Holzmann Y., Zeiher A.M., Dimmeler S. Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation. JBiol Chem 2002, 277:9684-9689.
-
(2002)
JBiol Chem
, vol.277
, pp. 9684-9689
-
-
Rossig, L.1
Badorff, C.2
Holzmann, Y.3
Zeiher, A.M.4
Dimmeler, S.5
-
125
-
-
0029664368
-
Polakis. Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
-
Rubinfeld B., Albert I., Porfiri E., Fiol C., Munemitsu S. Polakis. Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 1996, 272:1023-1026.
-
(1996)
Science
, vol.272
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
-
126
-
-
84865643742
-
INPP4A/INPP4B and P-Rex proteins: related but different?
-
Rynkiewicz N.K., Liu H.J., Balamatsias D., Mitchell C.A. INPP4A/INPP4B and P-Rex proteins: related but different?. Adv Biol Regul 2012, 52:265-279.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 265-279
-
-
Rynkiewicz, N.K.1
Liu, H.J.2
Balamatsias, D.3
Mitchell, C.A.4
-
127
-
-
84874005557
-
Characterization of the role of Fhit in suppression of DNA damage
-
Saldivar J.C., Bene J., Hosseini S.A., Miuma S., Horton S., Heerema N.A., et al. Characterization of the role of Fhit in suppression of DNA damage. Adv Biol Regul 2013, 53:77-85.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 77-85
-
-
Saldivar, J.C.1
Bene, J.2
Hosseini, S.A.3
Miuma, S.4
Horton, S.5
Heerema, N.A.6
-
128
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N., Meijer L., Skaltsounis L., Greengard P., Brivanlou A.H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med 2004, 10:55-63.
-
(2004)
Nat Med
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
129
-
-
33745374264
-
GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction
-
Sayas C.L., Ariaens A., Ponsioen B., Moolenaar W.H. GSK-3 is activated by the tyrosine kinase Pyk2 during LPA1-mediated neurite retraction. Mol Biol Cell 2006, 17:1834-1844.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 1834-1844
-
-
Sayas, C.L.1
Ariaens, A.2
Ponsioen, B.3
Moolenaar, W.H.4
-
130
-
-
23044444841
-
Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation
-
Shakoori A., Ougolkov A., Yu Z.W., Zhang B., Modarressi M.H., Billadeau D.D., et al. Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 2005, 334:1365-1373.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1365-1373
-
-
Shakoori, A.1
Ougolkov, A.2
Yu, Z.W.3
Zhang, B.4
Modarressi, M.H.5
Billadeau, D.D.6
-
131
-
-
84874011550
-
Structural insight into inositol pyrophosphate turnover
-
Shears S.B., Weaver J.D., Wang H. Structural insight into inositol pyrophosphate turnover. Adv Biol Regul 2013, 53:19-27.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 19-27
-
-
Shears, S.B.1
Weaver, J.D.2
Wang, H.3
-
132
-
-
84874005088
-
Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling
-
Shiizaki S., Naguro I., Ichijo H. Activation mechanisms of ASK1 in response to various stresses and its significance in intracellular signaling. Adv Biol Regul 2013, 53:135-144.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 135-144
-
-
Shiizaki, S.1
Naguro, I.2
Ichijo, H.3
-
133
-
-
80053369101
-
Acquired radioresistance of cancer and the AKT/GSK3beta/cyclin D1 overexpression cycle
-
Shimura T. Acquired radioresistance of cancer and the AKT/GSK3beta/cyclin D1 overexpression cycle. JRadiation Res 2011, 52:539-544.
-
(2011)
JRadiation Res
, vol.52
, pp. 539-544
-
-
Shimura, T.1
-
134
-
-
82755187773
-
Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation
-
Shin S., Wolgamott L., Yu Y., Blenis J., Yoon S.O. Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation. Proc Natl Acad Sci USA 2011, 108:1204-1213.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 1204-1213
-
-
Shin, S.1
Wolgamott, L.2
Yu, Y.3
Blenis, J.4
Yoon, S.O.5
-
135
-
-
84858718675
-
Glycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1)
-
Shin S., Wolgamott L., Yoon S.O. Glycogen synthase kinase (GSK)-3 and mammalian target of rapamycin complex 1 (mTORC1) cooperate to regulate protein S6 kinase 1 (S6K1). Cell Cycle 2012, 11:1053-1054.
-
(2012)
Cell Cycle
, vol.11
, pp. 1053-1054
-
-
Shin, S.1
Wolgamott, L.2
Yoon, S.O.3
-
136
-
-
84865616444
-
Regulation of diacylglycerol kinase by phosphorylation
-
Shirai Y., Ikeda M., Saito N. Regulation of diacylglycerol kinase by phosphorylation. Adv Biol Regul 2012, 52:239-247.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 239-247
-
-
Shirai, Y.1
Ikeda, M.2
Saito, N.3
-
137
-
-
0042872887
-
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice
-
So C.W., Karsunky H., Passegué E., Cozzio A., Weissman I.L., Cleary M.L. MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell 2003, 3:161-171.
-
(2003)
Cancer Cell
, vol.3
, pp. 161-171
-
-
So, C.W.1
Karsunky, H.2
Passegué, E.3
Cozzio, A.4
Weissman, I.L.5
Cleary, M.L.6
-
138
-
-
43549095900
-
Down-regulation of Notch-dependent transcription by Akt invitro
-
Song J., Park S., Kim M., Shin I. Down-regulation of Notch-dependent transcription by Akt invitro. FEBS Lett 2008, 582:1693-1699.
-
(2008)
FEBS Lett
, vol.582
, pp. 1693-1699
-
-
Song, J.1
Park, S.2
Kim, M.3
Shin, I.4
-
139
-
-
0027960448
-
Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
-
Stambolic V., Woodgett J.R. Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochem J 1994, 303:701-704.
-
(1994)
Biochem J
, vol.303
, pp. 701-704
-
-
Stambolic, V.1
Woodgett, J.R.2
-
140
-
-
0021239388
-
Failure of lithium to limit neutropenia significantly during induction therapy of acute myelogenous leukemia. A Southeastern Cancer Study Group study
-
Stein R.S., Vogler W.R., Lefante J. Failure of lithium to limit neutropenia significantly during induction therapy of acute myelogenous leukemia. A Southeastern Cancer Study Group study. Am J Clin Oncol 1984, 7:365-369.
-
(1984)
Am J Clin Oncol
, vol.7
, pp. 365-369
-
-
Stein, R.S.1
Vogler, W.R.2
Lefante, J.3
-
141
-
-
79959233776
-
What are the bona fide GSK3 substrates?
-
Article ID 505607
-
Sutherland C. What are the bona fide GSK3 substrates?. Int J Alzheimer's Dis 2011, 23. Article ID 505607.
-
(2011)
Int J Alzheimer's Dis
, pp. 23
-
-
Sutherland, C.1
-
142
-
-
0027515127
-
Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling
-
Sutherland C., Leighton I.A., Cohen P. Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling. Biochem J 1993, 296:15-19.
-
(1993)
Biochem J
, vol.296
, pp. 15-19
-
-
Sutherland, C.1
Leighton, I.A.2
Cohen, P.3
-
143
-
-
33845721880
-
GSK3beta positively regulates Hedgehog signaling through Sufu in mammalian cells
-
Takenaka K., Kise Y., Miki H. GSK3beta positively regulates Hedgehog signaling through Sufu in mammalian cells. Biochem Biophys Res Commun 2007, 353:501-508.
-
(2007)
Biochem Biophys Res Commun
, vol.353
, pp. 501-508
-
-
Takenaka, K.1
Kise, Y.2
Miki, H.3
-
144
-
-
25444519182
-
Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells
-
Tan J., Zhuang L., Leong H.S., Iyer N.G., Liu E.T., Yu Q. Pharmacologic modulation of glycogen synthase kinase-3beta promotes p53-dependent apoptosis through a direct Bax-mediated mitochondrial pathway in colorectal cancer cells. Cancer Res 2005, 65:9012-9020.
-
(2005)
Cancer Res
, vol.65
, pp. 9012-9020
-
-
Tan, J.1
Zhuang, L.2
Leong, H.S.3
Iyer, N.G.4
Liu, E.T.5
Yu, Q.6
-
145
-
-
43249106330
-
Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation
-
Thornton T.M., Pedraza-Alva G., Deng B., Wood C.D., Aronshtam A., Clements J.L., et al. Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation. Science 2008, 320:667-670.
-
(2008)
Science
, vol.320
, pp. 667-670
-
-
Thornton, T.M.1
Pedraza-Alva, G.2
Deng, B.3
Wood, C.D.4
Aronshtam, A.5
Clements, J.L.6
-
146
-
-
84865652356
-
Achieving specificity in Akt signaling in cancer
-
Toker A. Achieving specificity in Akt signaling in cancer. Adv Biol Regul 2012, 52:78-87.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 78-87
-
-
Toker, A.1
-
147
-
-
84874008868
-
Diacylglycerol kinase: regulation and stability
-
Tu-Sekine B., Goldschmidt H., Petro E., Raben D.M. Diacylglycerol kinase: regulation and stability. Adv Biol Regul 2013, 53:118-126.
-
(2013)
Adv Biol Regul
, vol.53
, pp. 118-126
-
-
Tu-Sekine, B.1
Goldschmidt, H.2
Petro, E.3
Raben, D.M.4
-
148
-
-
80052899298
-
AGSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells
-
Tullai J.W., Graham J.R., Cooper G.M. AGSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells. Cell Cycle 2011, 10:3072-3077.
-
(2011)
Cell Cycle
, vol.10
, pp. 3072-3077
-
-
Tullai, J.W.1
Graham, J.R.2
Cooper, G.M.3
-
149
-
-
83255186748
-
Feedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage response
-
Vadysirisack D.D., Baenke F., Ory B., Lei K., Ellisen L.W. Feedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage response. Mol Cell Biol 2011, 31:4356-4365.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 4356-4365
-
-
Vadysirisack, D.D.1
Baenke, F.2
Ory, B.3
Lei, K.4
Ellisen, L.W.5
-
150
-
-
84858608957
-
AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications
-
Vakana E., Platanias L.C. AMPK in BCR-ABL expressing leukemias. Regulatory effects and therapeutic implications. Oncotarget 2011, 2:1322-1328.
-
(2011)
Oncotarget
, vol.2
, pp. 1322-1328
-
-
Vakana, E.1
Platanias, L.C.2
-
151
-
-
84865656107
-
Regulation of autophagy by Forkhead box (FOX) O transcription factors
-
van der Vos K.E., Gomez-Puerto C., Coffer P.J. Regulation of autophagy by Forkhead box (FOX) O transcription factors. Adv Biol Regul 2012, 52:122-136.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 122-136
-
-
van der Vos, K.E.1
Gomez-Puerto, C.2
Coffer, P.J.3
-
152
-
-
0037124057
-
Wnt signaling controls the phosphorylation status of beta-catenin
-
van Noort M., Meeldijk J., van der Zee R., Destree O., Clevers H. Wnt signaling controls the phosphorylation status of beta-catenin. JBiol Chem 2002, 277:17901-17905.
-
(2002)
JBiol Chem
, vol.277
, pp. 17901-17905
-
-
van Noort, M.1
Meeldijk, J.2
van der Zee, R.3
Destree, O.4
Clevers, H.5
-
153
-
-
33845806853
-
Adiponectin modulates the glycogen synthase kinase-3beta/betacatenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice
-
Wang Y., Lam J.B., Lam K.S., Liu J., Lam M.C., Hoo R.L., et al. Adiponectin modulates the glycogen synthase kinase-3beta/betacatenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice. Cancer Res 2006, 66:11462-11470.
-
(2006)
Cancer Res
, vol.66
, pp. 11462-11470
-
-
Wang, Y.1
Lam, J.B.2
Lam, K.S.3
Liu, J.4
Lam, M.C.5
Hoo, R.L.6
-
154
-
-
55249120170
-
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
-
Wang Z., Smith K.S., Murphy M., Piloto O., Somervaille T.C., Cleary M.L. Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy. Nature 2008, 455:1205-1209.
-
(2008)
Nature
, vol.455
, pp. 1205-1209
-
-
Wang, Z.1
Smith, K.S.2
Murphy, M.3
Piloto, O.4
Somervaille, T.C.5
Cleary, M.L.6
-
155
-
-
77953233857
-
GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis
-
Wang Z., Iwasaki M., Ficara F., Lin C., Matheny C., Wong S.H., et al. GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis. Cancer Cell 2010, 17:597-608.
-
(2010)
Cancer Cell
, vol.17
, pp. 597-608
-
-
Wang, Z.1
Iwasaki, M.2
Ficara, F.3
Lin, C.4
Matheny, C.5
Wong, S.H.6
-
156
-
-
79955548609
-
Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response
-
Wang H., Brown J., Gu Z., Garcia C.A., Liang R., Alard P., et al. Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response. JImmunol 2011, 186:5217-5226.
-
(2011)
JImmunol
, vol.186
, pp. 5217-5226
-
-
Wang, H.1
Brown, J.2
Gu, Z.3
Garcia, C.A.4
Liang, R.5
Alard, P.6
-
157
-
-
0141591688
-
Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation
-
Welcker M., Singer J., Loeb K.R., Grim J., Bloecher A., Gurien-West M., et al. Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation. Mol Cell 2003, 12:381-392.
-
(2003)
Mol Cell
, vol.12
, pp. 381-392
-
-
Welcker, M.1
Singer, J.2
Loeb, K.R.3
Grim, J.4
Bloecher, A.5
Gurien-West, M.6
-
158
-
-
56549128268
-
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
-
Wilson A., Laurenti E., Oser G., van der Wath R.C., Blanco-Bose W., Jaworski M., et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 2008, 135:1118-1129.
-
(2008)
Cell
, vol.135
, pp. 1118-1129
-
-
Wilson, A.1
Laurenti, E.2
Oser, G.3
van der Wath, R.C.4
Blanco-Bose, W.5
Jaworski, M.6
-
159
-
-
0025286104
-
Molecular cloning and expression of glycogen synthase kinase-3/factor A
-
Woodgett J.R. Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J 1990, 9:2431-2438.
-
(1990)
EMBO J
, vol.9
, pp. 2431-2438
-
-
Woodgett, J.R.1
-
160
-
-
77649129121
-
GSK3: a multifaceted kinase in Wnt signaling
-
Wu D., Pan W. GSK3: a multifaceted kinase in Wnt signaling. Trends Biochem Sci 2010, 35:161-168.
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 161-168
-
-
Wu, D.1
Pan, W.2
-
161
-
-
84865649744
-
Diverse cellular and physiological roles of phospholipase C-1
-
Yang Y.R., Choi J.H., Chang J.S., Kwon H.M., Jang H.J., Ryu S.H., et al. Diverse cellular and physiological roles of phospholipase C-1. Adv Biol Regul 2012, 52:138-151.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 138-151
-
-
Yang, Y.R.1
Choi, J.H.2
Chang, J.S.3
Kwon, H.M.4
Jang, H.J.5
Ryu, S.H.6
-
162
-
-
78650003931
-
Beta-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells
-
Yeung J., Esposito M.T., Gandillet A., Zeisig B.B., Griessinger E., Bonnet D., et al. beta-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells. Cancer Cell 2010, 18:606-618.
-
(2010)
Cancer Cell
, vol.18
, pp. 606-618
-
-
Yeung, J.1
Esposito, M.T.2
Gandillet, A.3
Zeisig, B.B.4
Griessinger, E.5
Bonnet, D.6
-
163
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz O.H., Valdez R., Theisen B.K., Guo W., Ferguson D.O., Wu H., et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 2006, 441:475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
-
164
-
-
84864567160
-
Epigenetic mechanisms in leukemia
-
Zaidi S.K., Trombly D.J., Dowdy C.R., Lian J.B., Stein J.L., van Wijnen A.J., et al. Epigenetic mechanisms in leukemia. Adv Biol Regul 2012, 52:369-376.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 369-376
-
-
Zaidi, S.K.1
Trombly, D.J.2
Dowdy, C.R.3
Lian, J.B.4
Stein, J.L.5
van Wijnen, A.J.6
-
165
-
-
28644439005
-
Adual-kinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng X., Tamai K., Doble B., Li S., Huang H., Habas R., et al. Adual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 2005, 438:873-877.
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
Li, S.4
Huang, H.5
Habas, R.6
-
166
-
-
38949194936
-
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
Zeng X., Huang H., Tamai K., Zhang X., Harada Y., Yokota C., et al. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 2008, 135:367-375.
-
(2008)
Development
, vol.135
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
Zhang, X.4
Harada, Y.5
Yokota, C.6
-
167
-
-
34250179471
-
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1
-
Zhao Y., Altman B.J., Coloff J.L., Herman C.E., Jacobs S.R., Wieman H.L., et al. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol 2007, 27:4328-4339.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4328-4339
-
-
Zhao, Y.1
Altman, B.J.2
Coloff, J.L.3
Herman, C.E.4
Jacobs, S.R.5
Wieman, H.L.6
-
168
-
-
80052866636
-
GSK3beta inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb
-
Zhou F., Zhang L., van Laar T., van Dam H., Ten Dijke P. GSK3beta inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb. Mol Biol Cell 2011, 22:3533-3540.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3533-3540
-
-
Zhou, F.1
Zhang, L.2
van Laar, T.3
van Dam, H.4
Ten Dijke, P.5
-
169
-
-
84855991351
-
ShRNA silencing glycogen synthase kinase-3 beta inhibits tumor growth and angiogenesis in pancreatic cancer
-
Zhou W., Wang L., Gou S.M., Wang T.L., Zhang M., Liu T., et al. shRNA silencing glycogen synthase kinase-3 beta inhibits tumor growth and angiogenesis in pancreatic cancer. Cancer Lett 2012, 316:178-186.
-
(2012)
Cancer Lett
, vol.316
, pp. 178-186
-
-
Zhou, W.1
Wang, L.2
Gou, S.M.3
Wang, T.L.4
Zhang, M.5
Liu, T.6
-
170
-
-
84861857167
-
The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death
-
Zou J., Majerus P.W., Wilson D.B., Schrade A., Chang S.C., Wilson M.P. The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death. Adv Biol Regul 2012, 52:282-289.
-
(2012)
Adv Biol Regul
, vol.52
, pp. 282-289
-
-
Zou, J.1
Majerus, P.W.2
Wilson, D.B.3
Schrade, A.4
Chang, S.C.5
Wilson, M.P.6
|