The structure of phosphorylated GSK-3β complexed with a peptide, FRATtide, that inhibits β-catenin phosphorylation

Structure

Volumn 9, Issue 12, 2001, Pages 1143-1152

  Bax, Benjamin ^a   Carter, Paul S ^a   Lewis, Ceri ^a   Guy, Angela R ^a   Bridges, Angela ^a   Tanner, Robert ^a   Pettman, Gary ^a   Mannix, Chris ^a   Culbert, Ainsley A ^a   Brown, Murray J B ^a   Smith, David G ^a   Reith, Alastair D ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Axin; FRAT; GSK 3; Kinase phosphorylation; Kinase structure; Protein protein interactions

Indexed keywords

AXIN; BETA CATENIN; CYCLIN DEPENDENT KINASE 2; GLYCOGEN SYNTHASE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PEPTIDE; PHOSPHOSERINE; PHOSPHOTYROSINE; SERINE; TYROSINE; VALINE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; INSECT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BETA CATENIN; BINDING SITES; BINDING, COMPETITIVE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CDC2-CDC28 KINASES; CELL LINE; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASES; CYTOSKELETAL PROTEINS; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; INSECTS; KINETICS; LIGANDS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SUBSTRATE SPECIFICITY; TRANS-ACTIVATORS;

ANIMALIA; INSECTA;

EID: 0035665719     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00679-7     Document Type: Article

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