-
1
-
-
31644442906
-
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
-
Huangfu D., and Anderson K.V. Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates. Development 133 (2006) 3-14
-
(2006)
Development
, vol.133
, pp. 3-14
-
-
Huangfu, D.1
Anderson, K.V.2
-
2
-
-
0035577854
-
Hedgehog signaling in animal development: paradigms and principles
-
Ingham P.W., and McMahon A.P. Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15 (2001) 3059-3087
-
(2001)
Genes Dev.
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
3
-
-
10744230965
-
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
-
Machold R., Hayashi S., Rutlin M., Muzumdar M.D., Nery S., Corbin J.G., Gritli-Linde A., Dellovade T., Porter J.A., Rubin L.L., Dudek H., McMahon A.P., and Fishell G. Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39 (2003) 937-950
-
(2003)
Neuron
, vol.39
, pp. 937-950
-
-
Machold, R.1
Hayashi, S.2
Rutlin, M.3
Muzumdar, M.D.4
Nery, S.5
Corbin, J.G.6
Gritli-Linde, A.7
Dellovade, T.8
Porter, J.A.9
Rubin, L.L.10
Dudek, H.11
McMahon, A.P.12
Fishell, G.13
-
4
-
-
0002452569
-
Developmental roles and clinical significance of hedgehog signaling
-
McMahon A.P., Ingham P.W., and Tabin C.J. Developmental roles and clinical significance of hedgehog signaling. Curr. Top. Dev. Biol. 53 (2003) 1-114
-
(2003)
Curr. Top. Dev. Biol.
, vol.53
, pp. 1-114
-
-
McMahon, A.P.1
Ingham, P.W.2
Tabin, C.J.3
-
5
-
-
4344586961
-
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer
-
Kubo M., Nakamura M., Tasaki A., Yamanaka N., Nakashima H., Nomura M., Kuroki S., and Katano M. Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res. 64 (2004) 6071-6074
-
(2004)
Cancer Res.
, vol.64
, pp. 6071-6074
-
-
Kubo, M.1
Nakamura, M.2
Tasaki, A.3
Yamanaka, N.4
Nakashima, H.5
Nomura, M.6
Kuroki, S.7
Katano, M.8
-
6
-
-
0345059765
-
Hedgehog signalling in cancer formation and maintenance
-
Pasca di Magliano M., and Hebrok M. Hedgehog signalling in cancer formation and maintenance. Nat. Rev. Cancer 3 (2003) 903-911
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 903-911
-
-
Pasca di Magliano, M.1
Hebrok, M.2
-
7
-
-
17144371524
-
Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer
-
Sanchez P., Clement V., Ruiz I., and Altaba A. Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer. Cancer Res. 15 (2005) 2990-2992
-
(2005)
Cancer Res.
, vol.15
, pp. 2990-2992
-
-
Sanchez, P.1
Clement, V.2
Ruiz, I.3
Altaba, A.4
-
8
-
-
13644261744
-
Activation of the hedgehog pathway in advanced prostate cancer
-
Sheng T., Li C., Zhang X., Chi S., He N., Chen K., McCormick F., Gatalica Z., and Xie J. Activation of the hedgehog pathway in advanced prostate cancer. Mol. Cancer 3 (2004) 29
-
(2004)
Mol. Cancer
, vol.3
, pp. 29
-
-
Sheng, T.1
Li, C.2
Zhang, X.3
Chi, S.4
He, N.5
Chen, K.6
McCormick, F.7
Gatalica, Z.8
Xie, J.9
-
9
-
-
0033533714
-
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1
-
Ding Q., Fukami S., Meng X., Nishizaki Y., Zhang X., Sasaki H., Dlugosz A., Nakafuku M., and Hui C. Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr. Biol. 9 (1999) 1119-11122
-
(1999)
Curr. Biol.
, vol.9
, pp. 1119-11122
-
-
Ding, Q.1
Fukami, S.2
Meng, X.3
Nishizaki, Y.4
Zhang, X.5
Sasaki, H.6
Dlugosz, A.7
Nakafuku, M.8
Hui, C.9
-
10
-
-
0033194243
-
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
Kogerman P., Grimm T., Kogerman L., Krause D., Unden A.B., Sandstedt B., Toftgard R., and Zaphiropoulos P.G. Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat. Cell Biol. 1 (1999) 312-319
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
Grimm, T.2
Kogerman, L.3
Krause, D.4
Unden, A.B.5
Sandstedt, B.6
Toftgard, R.7
Zaphiropoulos, P.G.8
-
11
-
-
4544353067
-
Suppressor of fused regulates Gli activity through a dual binding mechanism
-
Merchant M., Vajdos F.F., Ultsch M., Maun H.R., Wendt U., Cannon J., Desmarais W., Lazarus R.A., de Vos A.M., and de Sauvage F.J. Suppressor of fused regulates Gli activity through a dual binding mechanism. Mol. Cell. Biol. 24 (2004) 8627-8641
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8627-8641
-
-
Merchant, M.1
Vajdos, F.F.2
Ultsch, M.3
Maun, H.R.4
Wendt, U.5
Cannon, J.6
Desmarais, W.7
Lazarus, R.A.8
de Vos, A.M.9
de Sauvage, F.J.10
-
12
-
-
0033491071
-
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
-
Stone D.M., Murone M., Luoh S., Ye W., Armanin M.P., Gurney A., Phillips H., Brush J., Goddard A., de Sauvage F.J., and Rosenthal A. Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J. Cell Sci. 112 (1999) 4437-4448
-
(1999)
J. Cell Sci.
, vol.112
, pp. 4437-4448
-
-
Stone, D.M.1
Murone, M.2
Luoh, S.3
Ye, W.4
Armanin, M.P.5
Gurney, A.6
Phillips, H.7
Brush, J.8
Goddard, A.9
de Sauvage, F.J.10
Rosenthal, A.11
-
13
-
-
0037117611
-
Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex
-
Cheng S.Y., and Bishop J.M. Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex. Proc. Natl. Acad. Sci. USA 16 (2002) 5442-5447
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.16
, pp. 5442-5447
-
-
Cheng, S.Y.1
Bishop, J.M.2
-
15
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S., and Cohen P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359 (2001) 1-16
-
(2001)
Biochem. J.
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
16
-
-
0037041470
-
Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus
-
Jia J., Amanai K., Wang G., Tang J., Wang B., and Jiang J. Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus. Nature 416 (2002) 548-552
-
(2002)
Nature
, vol.416
, pp. 548-552
-
-
Jia, J.1
Amanai, K.2
Wang, G.3
Tang, J.4
Wang, B.5
Jiang, J.6
-
17
-
-
33745858643
-
GLi2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase
-
Bhatia N., Thiyagarajan S., Elcheva I., Saleem M., Dlugosz A., Mukhtar H., and Spiegelman V.S. GLi2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase. J. Biol. Chem. 281 (2006) 19320-19326
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 19320-19326
-
-
Bhatia, N.1
Thiyagarajan, S.2
Elcheva, I.3
Saleem, M.4
Dlugosz, A.5
Mukhtar, H.6
Spiegelman, V.S.7
-
18
-
-
33646270662
-
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
-
Pan Y., Bai C.B., Joyner A.L., and Wang B. Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol. Cell. Biol. 26 (2006) 3365-3377
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3365-3377
-
-
Pan, Y.1
Bai, C.B.2
Joyner, A.L.3
Wang, B.4
-
19
-
-
33646869503
-
Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFβTrCP
-
Tempe D., Casas M., Karaz S., Blanchet-Tournier M.F., and Concordet J.P. Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFβTrCP. Mol. Cell. Biol. 26 (2006) 4316-4326
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 4316-4326
-
-
Tempe, D.1
Casas, M.2
Karaz, S.3
Blanchet-Tournier, M.F.4
Concordet, J.P.5
-
20
-
-
30444437000
-
Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing
-
Wang B., and Li Y. Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing. Proc. Natl. Acad. Sci. USA 103 (2006) 33-38
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 33-38
-
-
Wang, B.1
Li, Y.2
-
21
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang B., Fallon J.F., and Beachy P.A. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100 (2000) 423-434
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
22
-
-
0031577463
-
Induction of osteogenic differentiation by hedgehog proteins
-
Nakamura T., Aikawa T., Iwamoto-Enomoto M., Iwamoto M., Higuchi Y., Pacifici M., Kinto N., Yamaguchi A., Noji S., Kurisu K., and Matsuya T. Induction of osteogenic differentiation by hedgehog proteins. Biochem. Biophys. Res. Commun. 237 (1997) 465-469
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 465-469
-
-
Nakamura, T.1
Aikawa, T.2
Iwamoto-Enomoto, M.3
Iwamoto, M.4
Higuchi, Y.5
Pacifici, M.6
Kinto, N.7
Yamaguchi, A.8
Noji, S.9
Kurisu, K.10
Matsuya, T.11
-
23
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N., Meijer L., Skaltsounis L., Greengard P., and Brivanlou A.H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 10 (2004) 55-63
-
(2004)
Nat. Med.
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
24
-
-
30044444251
-
Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation
-
Trowbridge J., Xenocostas A., Moon R.T., and Bhatia M. Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation. Nat. Med. 12 (2006) 89-98
-
(2006)
Nat. Med.
, vol.12
, pp. 89-98
-
-
Trowbridge, J.1
Xenocostas, A.2
Moon, R.T.3
Bhatia, M.4
|