Wilms tumor suppressor WTX negatively regulates WNT/β-catenin signaling

Science

Volumn 316, Issue 5827, 2007, Pages 1043-1046

  Major, Michael B ^a   Camp, Nathan D ^a   Berndt, Jason D ^a   Yi, Xianhua ^a   Goldenberg, Seth J ^a   Hubbert, Charlotte ^a   Biechele, Travis L ^a   Gingras, Anne Claude ^b   Zheng, Ning ^a   MacCoss, Michael J ^a   Angers, Stephane ^a,c   Moon, Randall T ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; SULFUR 35; WNT PROTEIN;

CANCER; FISH; MUTATION; PROTEIN; TUMOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL STRAIN HEK293; COLON POLYPOSIS; COLORECTAL CANCER; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; ISOTOPE LABELING; MASS SPECTROMETRY; MELANOMA; NEPHROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING; XENOPUS; ZEBRA FISH;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL LINE; CELL LINE, TUMOR; CELL NUCLEUS; CYTOPLASM; GENES, WILMS TUMOR; HUMANS; KIDNEY NEOPLASMS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEOMICS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; WILMS TUMOR; WNT PROTEINS; ZEBRAFISH;

DANIO RERIO;

EID: 34249061491     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science/1141515     Document Type: Article

References (12)

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12. Purified β-catenin was a kind gift from W. Xu, University of Washington, Seattle. C.H. is supported by a post-doctoral F32 NIH National Research Service Award training grant.