-
1
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya, T., Morrison, S. J., Clarke, M. F. & Weissman, I. L. Stem cells, cancer, and cancer stem cells. Nature 414, 105-111 (2001).
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
Weissman, I.L.4
-
2
-
-
6044229354
-
Concepts of human leukemic development
-
Warner, J. K., Wang, J. C., Hope, K. J., Jin, L. & Dick, J. E. Concepts of human leukemic development. Oncogene 23, 7164-7177 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 7164-7177
-
-
Warner, J.K.1
Wang, J.C.2
Hope, K.J.3
Jin, L.4
Dick, J.E.5
-
3
-
-
5444256238
-
Self-renewal and solid tumor stem cells
-
Al-Hajj, M. & Clarke, M. F. Self-renewal and solid tumor stem cells. Oncogene 23, 7274-7282 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 7274-7282
-
-
Al-Hajj, M.1
Clarke, M.F.2
-
4
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet, D. & Dick, J. E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nature Med. 3, 730-737 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
5
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot, T. et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367, 645-648 (1994).
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
-
6
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh, S. K. et al. Identification of human brain tumour initiating cells. Nature 432, 396-401 (2004).
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
-
7
-
-
3943088431
-
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
-
Jamieson, C. H. et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N. Engl. J. Med. 351, 657-667 (2004).
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 657-667
-
-
Jamieson, C.H.1
-
8
-
-
19944385935
-
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
-
Huntly, B. J. et al. MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell 6, 587-596 (2004).
-
(2004)
Cancer Cell
, vol.6
, pp. 587-596
-
-
Huntly, B.J.1
-
9
-
-
0346100567
-
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
-
Cozzio, A. et al. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev. 17, 3029-3035 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 3029-3035
-
-
Cozzio, A.1
-
10
-
-
0042872887
-
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice
-
So, C. W. et al. MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell 3, 161-171 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 161-171
-
-
So, C.W.1
-
11
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi, K., Traver, D., Miyamoto, T. & Weissman, I. L. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404, 193-197 (2000).
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
12
-
-
0030791974
-
Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
-
Lavau, C., Szilvassy, S. J., Slany, R. & Cleary, M. L. Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. EMBO J. 16, 4226-4237 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 4226-4237
-
-
Lavau, C.1
Szilvassy, S.J.2
Slany, R.3
Cleary, M.L.4
-
13
-
-
15844394270
-
An MLL-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: A method to create fusion oncogenes
-
Corral, J. et al. An MLL-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes. Cell 85, 853-861 (1996).
-
(1996)
Cell
, vol.85
, pp. 853-861
-
-
Corral, J.1
-
14
-
-
13444311619
-
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease
-
Wang, J. et al. Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease. EMBO J. 24, 368-381 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 368-381
-
-
Wang, J.1
-
15
-
-
27144493049
-
Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis
-
Drynan, L. F. et al. Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis. EMBO J. 24, 3136-3146 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 3136-3146
-
-
Drynan, L.F.1
-
16
-
-
0037131389
-
"Stemness": Transcriptional profiling of embryonic and adult stem cells
-
Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R. C. & Melton, D. A. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 298, 597-600 (2002).
-
(2002)
Science
, vol.298
, pp. 597-600
-
-
Ramalho-Santos, M.1
Yoon, S.2
Matsuzaki, Y.3
Mulligan, R.C.4
Melton, D.A.5
-
17
-
-
9144236224
-
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization
-
Zeisig, B. B. et al. Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization. Mol. Cell. Biol. 24, 617-628 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 617-628
-
-
Zeisig, B.B.1
-
18
-
-
1442356858
-
Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia
-
Kumar, A. R. et al. Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia. Blood 103, 1823-1828 (2004).
-
(2004)
Blood
, vol.103
, pp. 1823-1828
-
-
Kumar, A.R.1
-
19
-
-
0041370095
-
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
-
Ayton, P. M. & Cleary, M. L. Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev. 17, 2298-2307 (2003).
-
(2003)
Genes Dev.
, vol.17
, pp. 2298-2307
-
-
Ayton, P.M.1
Cleary, M.L.2
-
20
-
-
18544375333
-
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
-
Armstrong, S. A. et al. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nature Genet. 30, 41-47 (2002).
-
(2002)
Nature Genet.
, vol.30
, pp. 41-47
-
-
Armstrong, S.A.1
-
21
-
-
1842579481
-
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9
-
So, C. W., Karsunky, H., Wong, P., Weissman, I. L. & Cleary, M. L. Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9. Blood 103, 3192-3199 (2004).
-
(2004)
Blood
, vol.103
, pp. 3192-3199
-
-
So, C.W.1
Karsunky, H.2
Wong, P.3
Weissman, I.L.4
Cleary, M.L.5
-
22
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
Kiel, M. J., Yilmaz, O. H., Iwashita, T., Terhorst, C. & Morrison, S. J. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121, 1109-1121 (2005).
-
(2005)
Cell
, vol.121
, pp. 1109-1121
-
-
Kiel, M.J.1
Yilmaz, O.H.2
Iwashita, T.3
Terhorst, C.4
Morrison, S.J.5
-
23
-
-
9444283773
-
Gene expression profiling of pediatric acute myelogenous leukemia
-
Ross, M. E. et al. Gene expression profiling of pediatric acute myelogenous leukemia. Blood 104, 3679-3687 (2004).
-
(2004)
Blood
, vol.104
, pp. 3679-3687
-
-
Ross, M.E.1
-
24
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-15550 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
25
-
-
1642562179
-
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation
-
Kolligs, F. T. et al. ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation. Cancer Cell 1, 145-155 (2002).
-
(2002)
Cancer Cell
, vol.1
, pp. 145-155
-
-
Kolligs, F.T.1
-
26
-
-
18744366334
-
Hox regulation of normal and leukemic hematopoietic stem cells
-
Abramovich, C. & Humphries, R. K. Hox regulation of normal and leukemic hematopoietic stem cells. Curr. Opin. Hematol. 12, 210-216 (2005).
-
(2005)
Curr. Opin. Hematol.
, vol.12
, pp. 210-216
-
-
Abramovich, C.1
Humphries, R.K.2
-
27
-
-
26844462131
-
MLL associates specifically with a subset of transcriptionally active target genes
-
Milne, T. A. et al. MLL associates specifically with a subset of transcriptionally active target genes. Proc. Natl Acad. Sci. USA 102, 14765-14770 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14765-14770
-
-
Milne, T.A.1
-
28
-
-
20844443663
-
Global and Hox-specific roles for the MLL1 methyltransferase
-
Guenther, M. G. et al. Global and Hox-specific roles for the MLL1 methyltransferase. Proc. Natl Acad. Sci. USA 102, 8603-8608 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8603-8608
-
-
Guenther, M.G.1
-
29
-
-
27144554190
-
Cooperating cancer-gene identification through oncogenic-retrovirus- induced insertional mutagenesis
-
Du, Y., Spence, S. E., Jenkins, N. A. & Copeland, N. G. Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis. Blood 106, 2498-2505 (2005).
-
(2005)
Blood
, vol.106
, pp. 2498-2505
-
-
Du, Y.1
Spence, S.E.2
Jenkins, N.A.3
Copeland, N.G.4
-
30
-
-
9244257908
-
An Mll-dependent Hox programme drives hematopoietic progenitor expansion
-
Ernst, P., Mabon, M., Davidson, A. J., Zon, L. I. & Korsmeyer, S. J. An Mll-dependent Hox programme drives hematopoietic progenitor expansion. Curr. Biol. 14, 2063-2069 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 2063-2069
-
-
Ernst, P.1
Mabon, M.2
Davidson, A.J.3
Zon, L.I.4
Korsmeyer, S.J.5
|