Deregulated GSK3β activity in colorectal cancer: Its association with tumor cell survival and proliferation

Biochemical and Biophysical Research Communications

Volumn 334, Issue 4, 2005, Pages 1365-1373

  Shakoori, Abbas ^a   Ougolkov, Andrei ^a,c   Zhi, Wei Yu ^a   Zhang, Bin ^a   Modarressi, Mohammad H ^b   Billadeau, Daniel D ^c   Mai, Masayoshi ^a   Takahashi, Yutaka ^a   Minamoto, Toshinari ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MAYO GRADUATE SCHOOL   (United States)

Author keywords

catenin; Apoptosis; Cell survival; Colorectal cancer; Glycogen synthase kinase 3 ; NF B; Phosphorylation; Proliferation; Therapeutic target; Wnt signaling

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; AR A 014418; ARA 014418; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3BETA; ONCOPROTEIN; UNCLASSIFIED DRUG; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER PATIENT; CELL PROLIFERATION; CELL SURVIVAL; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR CELL; CLINICAL TRIAL; COLORECTAL TUMOR; DOWN REGULATION; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; TUMOR CELL LINE;

ADULT; AGED; AGED, 80 AND OVER; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; DOWN-REGULATION; ENZYME ACTIVATION; FEMALE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MALE; MIDDLE AGED;

EID: 23044444841     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.07.041     Document Type: Article

References (27)

1. J.R. Jass, V.L.J. Whitehall, J. Young, and B.A. Leggett Emerging concepts in colorectal neoplasia Gastroenterology 123 2003 862 876
2. P. Polakis The oncogenic activation of beta-catenin Curr. Opin. Genet. Dev. 9 1999 15 21
3. A.V. Ougolkov, K. Yamashita, M. Mai, and T. Minamoto Oncogenic β-catenin and MMP-7 (matrilysin) cosegregate in late-stage clinical colon cancer Gastroenterology 122 2002 60 71
4. A.S. Manoukian, and J.R. Woodgett Role of glycogen synthase kinase-3 in cancer: regulation by Wnts and other signaling pathways Adv. Cancer Res. 84 2002 203 229
5. B.W. Doble, and J.R. Woodgett GSK-3: tricks of the trade for a multi-tasking kinase J. Cell Sci. 116 2003 1175 1186
6. R.S. Jope, and G.V.W. Johnson The glamour and gloom of glycogen synthase kinase-3 Trends Biochem. Sci. 29 2004 95 102
7. X. Liao, L. Zhang, J.B. Thrasher, J. Du, and B. Li Glycogen synthase kinase-3β suppression eliminates tumor necrosis factor-related apoptosis-inducing resistance in prostate cancer Mol. Cancer Ther. 2 2003 1215 1222
8. M. Mazor, Y. Kawano, H. Zhu, J. Waxman, and R.M. Kypta Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth Oncogene 23 2004 7882 7892
9. K.P. Hoeflich, J. Luo, E.A. Rubie, M.S. Tsao, O. Jin, and J.R. Woodgett Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation Nature 406 2000 86 90
10. R.F. Schwabe, and D.A. Brenner Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes Am. J. Physiol. Gastrointest. Liver Physiol. 283 2002 G204 G211
11. A. Ougolkov, B. Zhang, K. Yamashita, V. Bilim, M. Mai, S.Y. Fuchs, and T. Minamoto Associations among β-TrCP, an E3 ubiquitin ligase receptor, β-catenin and NF-κB in colorectal cancer J. Natl. Cancer Inst. 96 2004 1161 1170
12. J. Gayet, X.P. Zhou, A. Duval, S. Rolland, J.-M. Hoang, P. Cottu, and R. Hamelin Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines Oncogene 20 2001 5025 5032
13. L.K. Sobin C. Wittekind UICC International Union Against Cancer. TNM Classification of Malignant Tumours fifth ed. 1997 Wiley New York 66 69
14. V. Adler, M.R. Pincus, T. Minamoto, S.Y. Fuchs, M.J. Bluth, P.W. Brandt-Rauf, F. Friedman, J.M. Chen, X.W. Wang, C.C. Harris, and Z. Ronai Conformation-dependent phosphorylation of p53 Proc. Natl. Acad. Sci. USA 94 1997 1686 1691
15. A. Shakoori, G. Fujii, S. Yoshimura, M. Kitamura, K. Nakayama, T. Ito, H. Ohno, and N. Nakamura Identification of a five-pass protein family localizing in the Golgi apparatus and the ER Biochem. Biophys. Res. Commun. 312 2003 850 857
16. P. Cohen, and M. Goedert GSK3 inhibitors: development and therapeutic potential Nat. Rev. Drug. Discov. 3 2004 479 487
17. L. Meijer, M.P. Flajolet, and P. Greengard Pharmacological inhibitors of glycogen synthase kinase 3 Trends Pharm. Sci. 25 2004 471 480
18. R.A. Gatenby, and E.T. Gawlinski The glycolytic phenotype in carcinogenesis and tumor invasion: insights through mathematical models Cancer Res. 63 2003 3847 3854
19. M. Sharma, W.W. Chuang, and Z. Sun Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3β inhibition and nuclear β-catenin accumulation J. Biol. Chem. 277 2002 30935 30941
20. D.A. Cross, D.R. Alessi, P. Cohen, M. Andjelkovich, and B.A. Hemmings Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B Nature 378 1995 785 789
21. A.A. Adjei Blocking oncogenic ras signaling for cancer therapy J. Natl. Cancer Inst. 93 2001 1062 1074
22. L. Wang, H.-K. Lin, Y.-C. Hu, S. Xie, L. Yang, and C. Chang Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen kinase 3β in prostate cells J. Biol. Chem. 279 2004 32444 32452
23. F.B. Hu, J.E. Manson, S. Liu, D. Hunter, G.A. Colditz, K.B. Michels, F.E. Speizer, and E. Giovannucci Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in woman J. Natl. Cancer Inst. 91 1999 542 547
24. D. Komninou, A. Ayonote, J.P. Richie Jr., and B. Rigas Insulin resistance and its contribution to colon carcinogenesis Exp. Biol. Med. (Maywood) 228 2003 396 405
25. R.V. Bhat, and S.L. Budd GSK3β signalling: casting a wide net in Alzheimer's disease Neurosignals 11 2002 251 261
26. Y. Cohen, A. Chetrit, Y. Cohen, P. Sirota, and B. Modan Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment Med. Oncol. 15 1998 32 36
27. S. Dihlmann, S. Klein, and M.v.K. Doeberitz Reduction of β-catenin/T-cell transcription factor signaling by aspirin and indomethacin is caused by an increased stabilization of phosphorylated β-catenin Mol. Cancer Ther. 2 2003 509 516