Hyperphosphorylation of tau by GSK-3β in Alzheimer's disease: The interaction of Aβ and sphingolipid mediators as a therapeutic target

Translational Neuroscience

Volumn 4, Issue 4, 2013, Pages 466-476

  Jembrek, Maja Jazvinšćak ^a,b   Babić, Mirjana ^c   Pivac, Nela ^a   Hof, Patrick R ^d   Šimić, Goran ^c  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b Croatian Academy of Medical Sciences Zagreb   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Amyloid ; Glycogen synthase kinase 3 ; Sphingolipids; Tau hyperphosphorylation

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CERAMIDE; GLYCOGEN SYNTHASE KINASE 3BETA; SPHINGOMYELIN PHOSPHODIESTERASE; TAU PROTEIN;

ALZHEIMER DISEASE; CATABOLISM; CELLULAR DISTRIBUTION; COMPLEX FORMATION; HUMAN; LIPOGENESIS; LOSS OF FUNCTION MUTATION; MOLECULAR STABILITY; NERVE CELL NECROSIS; NERVE FIBER GROWTH; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW;

EID: 84893001977     PISSN: 20813856     EISSN: 20816936     Source Type: Journal    
DOI: 10.2478/s13380-013-0144-z     Document Type: Review

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