Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling

FASEB Journal

Volumn 23, Issue 3, 2009, Pages 751-763

  Mukhopadhyay, Archana ^a,b   Saddoughi, Sahar A ^a,b   Song, Pengfei ^a,b   Sultan, Iyad ^a,b,d   Ponnusamy, Suriyan ^a,b   Senkal, Can E ^a,b   Snook, Christopher F ^a   Arnold, Hugh K ^c   Sears, Rosalie C ^c   Hannun, Yusuf A ^a,b   Ogretmen, Besim ^a,b  

^a Department of Molecular Biology ^*  (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d KING HUSSEIN CANCER CENTER   (Jordan)

Author keywords

Bioactive lipids; C Myc degradation

Indexed keywords

BINDING PROTEIN; CERAMIDE; INHIBITOR 2 OF PROTEIN PHOSPHATASE 2A; MUTANT PROTEIN; MYC PROTEIN; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TUMOR XENOGRAFT; WILD TYPE;

AMINO ACID SEQUENCE; CELL LINE, TUMOR; CERAMIDES; CHROMOSOMAL PROTEINS, NON-HISTONE; DOWN-REGULATION; GENE EXPRESSION REGULATION; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN PHOSPHATASE 2; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; TRANSCRIPTION FACTORS;

CENTROPOMIDAE;

EID: 61549109860     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-120550     Document Type: Article

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