Neutral sphingomyelinase activation precedes NADPH oxidase-dependent damage in neurons exposed to the proinflammatory cytokine tumor necrosis factor-α

Journal of Neuroscience Research

Volumn 90, Issue 1, 2012, Pages 229-242

  Barth, Brian M ^a,b   Gustafson, Sally J ^b   Kuhn, Thomas B ^b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ALASKA FAIRBANKS   (United States)

Author keywords

Ceramide; NADPH oxidase; Neuroinflammation; Sphingomyelinase; Sphingosine kinase

Indexed keywords

CERAMIDE; MAGNESIUM; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BRAIN CELL; CARBONYLATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; GROWTH CONE; HUMAN; HUMAN CELL; HYDROLYSIS; NERVE CELL; NERVE FIBER GROWTH; NERVE INJURY; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SPINAL GANGLION;

ANIMALS; APOPTOSIS; CELL MEMBRANE; CERAMIDES; CEREBRAL CORTEX; CHICK EMBRYO; DRUG INTERACTIONS; ENZYME INHIBITORS; GROWTH CONES; HUMANS; MAGNESIUM; NADPH OXIDASE; NEURITES; NEUROBLASTOMA; NEURONS; PALMITATES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 81255159138     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22748     Document Type: Article

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