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Volumn 29, Issue 3, 2012, Pages 537-547

Increased ceramide in brains with alzheimer's and other neurodegenerative diseases

Author keywords

Alzheimer's disease; ceramide; neurodegeneration; sphingolipid biosynthesis; sphingolipid regulation

Indexed keywords

CERAMIDE; FATTY ACID; SPHINGOLIPID;

EID: 84859409865     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2011-111202     Document Type: Article
Times cited : (199)

References (23)
  • 1
    • 34247204182 scopus 로고    scopus 로고
    • Dementia syndromes: Evaluation and treatment
    • DOI 10.1586/14737175.7.4.407
    • Scott KR, Barrett AM (2007) Dementia syndromes: Evaluation and treatment. Expert Rev Neurother 7, 407-422. (Pubitemid 46623362)
    • (2007) Expert Review of Neurotherapeutics , vol.7 , Issue.4 , pp. 407-422
    • Scott, K.R.1    Barrett, A.M.2
  • 2
    • 58849160520 scopus 로고    scopus 로고
    • Ceramide and neurode-generation: Susceptibility of neurons and oligodendrocytes to cell damage and death
    • Jana A, Hogan EL, Pahan K (2009) Ceramide and neurode-generation: Susceptibility of neurons and oligodendrocytes to cell damage and death. J Neurol Sci 278, 5-15.
    • (2009) J Neurol Sci , vol.278 , pp. 5-15
    • Jana, A.1    Hogan, E.L.2    Pahan, K.3
  • 4
    • 0037203342 scopus 로고    scopus 로고
    • Ceramideinapop-tosis: An overview and current perspectives
    • Pettus BJ, Chalfant CE, Hannun YA (2002) Ceramideinapop-tosis: An overview and current perspectives. Biochim Biophys Acta 1585, 114-125.
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 114-125
    • Pettus, B.J.1    Chalfant, C.E.2    Hannun, Y.A.3
  • 6
    • 43849088670 scopus 로고    scopus 로고
    • C18 ceramide analysis in mammalian cells employing reversed-phase high-performance liquid chro-matography tandem mass spectrometry
    • Haynes TA, Duerksen-Hughes PJ, Filippova M, Filippov V, Zhang K (2008) C18 ceramide analysis in mammalian cells employing reversed-phase high-performance liquid chro-matography tandem mass spectrometry. Anal Biochem 378, 80-86.
    • (2008) Anal Biochem , vol.378 , pp. 80-86
    • Haynes, T.A.1    Duerksen-Hughes, P.J.2    Filippova, M.3    Filippov, V.4    Zhang, K.5
  • 7
    • 77951091722 scopus 로고    scopus 로고
    • Quantification of ceramide species in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry
    • Kasumov T, Huang H, Chung YM, Zhang R, McCullough AJ, Kirwan JP (2010) Quantification of ceramide species in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry. Anal Biochem 401, 154-161.
    • (2010) Anal Biochem , vol.401 , pp. 154-161
    • Kasumov, T.1    Huang, H.2    Chung, Y.M.3    Zhang, R.4    McCullough, A.J.5    Kirwan, J.P.6
  • 8
    • 79959716331 scopus 로고    scopus 로고
    • Quantification of ceramide levels in mammalian cells by high performance liquid chro-matography coupled to tandem mass spectrometry with multiple-reaction-monitoring mode (HPLC-MS/MS-MRM)
    • Zhang K, Haynes T-AS, Filippova M, Filippov V, Duerksen-Hughes PJ (2011) Quantification of ceramide levels in mammalian cells by high performance liquid chro-matography coupled to tandem mass spectrometry with multiple-reaction- monitoring mode (HPLC-MS/MS-MRM). Analytical Methods 3, 1193-1197.
    • (2011) Analytical Methods , vol.3 , pp. 1193-1197
    • Zhang, K.1    T-As, H.2    Filippova, M.3    Filippov, V.4    Duerksen-Hughes, P.J.5
  • 9
    • 74149083982 scopus 로고    scopus 로고
    • Deregulation of sphingolipid metabolism in Alzheimer's disease
    • He X, Huang Y, Li B, Gong CX, Schuchman EH (2010) Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol Aging 31, 398-408.
    • (2010) Neurobiol Aging , vol.31 , pp. 398-408
    • He, X.1    Huang, Y.2    Li, B.3    Gong, C.X.4    Schuchman, E.H.5
  • 11
    • 41949140023 scopus 로고    scopus 로고
    • Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
    • Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH Jr, Futerman AH (2008) Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 283, 5677-5684.
    • (2008) J Biol Chem , vol.283 , pp. 5677-5684
    • Laviad, E.L.1    Albee, L.2    Pankova-Kholmyansky, I.3    Epstein, S.4    Park, H.5    Merrill Jr., A.H.6    Futerman, A.H.7
  • 12
    • 9644277091 scopus 로고    scopus 로고
    • Sphingolipid metabolites in neural signalling and function
    • DOI 10.1016/j.brainresrev.2004.07.014, PII S0165017304001122
    • Colombaioni L, Garcia-Gil M (2004) Sphingolipid metabolites in neural signalling and function. Brain Res Brain Res Rev 46, 328-355. (Pubitemid 39574333)
    • (2004) Brain Research Reviews , vol.46 , Issue.3 , pp. 328-355
    • Colombaioni, L.1    Garcia-Gil, M.2
  • 15
    • 33947577504 scopus 로고    scopus 로고
    • Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: A shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease?
    • DOI 10.1007/s11064-007-9297-x
    • Katsel P, Li C, Haroutunian V (2007) Gene expression alterations in the sphingolipid metabolism pathways during progression of dementia and Alzheimer's disease: A shift toward ceramide accumulation at the earliest recognizable stages of Alzheimer's disease? Neurochem Res 32, 845-856. (Pubitemid 46481322)
    • (2007) Neurochemical Research , vol.32 , Issue.4-5 , pp. 845-856
    • Katsel, P.1    Li, C.2    Haroutunian, V.3
  • 17
    • 38349051098 scopus 로고    scopus 로고
    • Glucosylce-ramide synthase decrease in frontal cortex of Alzheimer brain correlates with abnormal increase in endogenous ceramides: Consequences to morphology and viability on enzyme suppression in cultured primary neurons
    • Marks N, Berg MJ, Saito M, Saito M (2008) Glucosylce-ramide synthase decrease in frontal cortex of Alzheimer brain correlates with abnormal increase in endogenous ceramides: Consequences to morphology and viability on enzyme suppression in cultured primary neurons. Brain Res 1191, 136-147.
    • (2008) Brain Res , vol.1191 , pp. 136-147
    • Marks, N.1    Berg, M.J.2    Saito, M.3    Saito, M.4
  • 19
    • 62749184862 scopus 로고    scopus 로고
    • Roles and regulation of secretory and lysosomal acid sphingomyelinase
    • Jenkins RW, Canals D, Hannun YA (2009) Roles and regulation of secretory and lysosomal acid sphingomyelinase. Cell Signal 21, 836-846.
    • (2009) Cell Signal , vol.21 , pp. 836-846
    • Jenkins, R.W.1    Canals, D.2    Hannun, Y.A.3
  • 21
    • 78649802553 scopus 로고    scopus 로고
    • Mammalian neutral sphingomyelinases: Regulation and roles in cell signaling responses
    • Wu BX, Clarke CJ, Hannun YA (2010) Mammalian neutral sphingomyelinases: Regulation and roles in cell signaling responses. Neuromolecular Med 12, 320-330.
    • (2010) Neuromolecular Med , vol.12 , pp. 320-330
    • Wu, B.X.1    Clarke, C.J.2    Hannun, Y.A.3
  • 22
    • 0035937488 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced ischemic tolerance is associated with increased levels of ceramide in brain and in plasma
    • DOI 10.1016/S0006-8993(01)02028-5, PII S0006899301020285
    • Zimmermann C, Ginis I, Furuya K, Klimanis D, Ruetzler C, Spatz M, Hallenbeck JM (2001) Lipopolysaccharide-induced ischemic tolerance is associated with increased levels of ceramide in brain and in plasma. Brain Res 895, 59-65. (Pubitemid 32231138)
    • (2001) Brain Research , vol.895 , Issue.1-2 , pp. 59-65
    • Zimmermann, C.1    Ginis, I.2    Furuya, K.3    Klimanis, D.4    Ruetzler, C.5    Spatz, M.6    Hallenbeck, J.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.