-
1
-
-
64349095390
-
An operational definition of epigenetics
-
Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes Dev. 23(7), 781-783 (2009
-
(2009)
Genes Dev
, vol.23
, Issue.7
, pp. 781-783
-
-
Berger, S.L.1
Kouzarides, T.2
Shiekhattar, R.3
Shilatifard, A.4
-
2
-
-
34249337761
-
Perceptions of epigenetics
-
Bird A. Perceptions of epigenetics. Nature 447(7143), 396-398 (2007
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 396-398
-
-
Bird, A.1
-
3
-
-
79958152841
-
Histone H4K20me3 and HP1alpha are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells
-
Wongtawan T, Taylor JE, Lawson KA, Wilmut I, Pennings S. Histone H4K20me3 and HP1alpha are late heterochromatin markers in development, but present in undifferentiated embryonic stem cells. J. Cell. Sci. 124(Pt 11), 1878-1890 (2011
-
(2011)
J. Cell. Sci
, vol.124
, Issue.PART 11
, pp. 1878-1890
-
-
Wongtawan, T.1
Taylor, J.E.2
Lawson, K.A.3
Wilmut, I.4
Pennings, S.5
-
4
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
Reik W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447(7143), 425-432 (2007
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 425-432
-
-
Reik, W.1
-
5
-
-
77954345408
-
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
-
Hajkova P, Jeffries SJ, Lee C, Miller N, Jackson SP, Surani MA. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 329(5987), 78-82 (2010
-
(2010)
Science
, vol.329
, Issue.5987
, pp. 78-82
-
-
Hajkova, P.1
Jeffries, S.J.2
Lee, C.3
Miller, N.4
Jackson, S.P.5
Surani, M.A.6
-
6
-
-
84881086323
-
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
-
Timp W, Feinberg AP. Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host. Nat. Rev. Cancer 13(7), 497-510 (2013
-
(2013)
Nat. Rev. Cancer
, vol.13
, Issue.7
, pp. 497-510
-
-
Timp, W.1
Feinberg, A.P.2
-
7
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
Hansen KD, Timp W, Bravo HC et al. Increased methylation variation in epigenetic domains across cancer types. Nat. Genet. 43(8), 768-775 (2011
-
(2011)
Nat. Genet
, vol.43
, Issue.8
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
-
8
-
-
84878441665
-
Genomic insights into cancer-Associated aberrant CpG island hypermethylation
-
Sproul D, Meehan RR. Genomic insights into cancer-Associated aberrant CpG island hypermethylation. Brief Funct. Genomics 12(3), 174-190 (2013
-
(2013)
Brief Funct. Genomics
, vol.12
, Issue.3
, pp. 174-190
-
-
Sproul, D.1
Meehan, R.R.2
-
9
-
-
84866844032
-
Tissue of origin determines cancer-Associated CpG island promoter hypermethylation patterns
-
Sproul D, Kitchen RR, Nestor CE et al. Tissue of origin determines cancer-Associated CpG island promoter hypermethylation patterns. Genome Biol. 13(10), R84 (2012
-
(2012)
Genome Biol
, vol.13
, Issue.10
-
-
Sproul, D.1
Kitchen, R.R.2
Nestor, C.E.3
-
10
-
-
84875333893
-
Redistribution of H3K27me3 upon DNA hypomethylation results in derepression of Polycomb target genes
-
(Epub ahead of print
-
Reddington JP, Perricone SM, Nestor CE et al. Redistribution of H3K27me3 upon DNA hypomethylation results in derepression of Polycomb target genes. Genome Biol. 14(3), R25 (2013) (Epub ahead of print
-
(2013)
Genome Biol
, vol.14
, Issue.3
-
-
Reddington, J.P.1
Perricone, S.M.2
Nestor, C.E.3
-
11
-
-
84861912630
-
Programming of DNA methylation patterns
-
Cedar H, Bergman Y. Programming of DNA methylation patterns. Annu. Rev. Biochem. 81, 97-117 (2012
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 97-117
-
-
Cedar, H.1
Bergman, Y.2
-
12
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99(3), 247-257 (1999
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
13
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69(6), 915-926 (1992
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
14
-
-
60849118096
-
A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development
-
Ashe A, Morgan DK, Whitelaw NC et al. A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development. Genome Biol. 9(12), R182 (2008
-
(2008)
Genome Biol
, vol.9
, Issue.12
-
-
Ashe, A.1
Morgan, D.K.2
Whitelaw, N.C.3
-
15
-
-
84875167169
-
Non-canonical functions of the DNA methylome in gene regulation
-
Reddington JP, Pennings S, Meehan RR. Non-canonical functions of the DNA methylome in gene regulation. Biochem. J. 451(1), 13-23 (2013
-
(2013)
Biochem. J.
, vol.451
, Issue.1
, pp. 13-23
-
-
Reddington, J.P.1
Pennings, S.2
Meehan, R.R.3
-
16
-
-
43049108039
-
Xdnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function
-
Dunican DS, Ruzov A, Hackett JA, Meehan RR. xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. Development 135(7), 1295-1302 (2008
-
(2008)
Development
, vol.135
, Issue.7
, pp. 1295-1302
-
-
Dunican, D.S.1
Ruzov, A.2
Hackett, J.A.3
Meehan, R.R.4
-
17
-
-
73449113904
-
Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
-
Hervouet E, Vallette FM, Cartron PF. Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 4(7), 487-499 (2009
-
(2009)
Epigenetics
, vol.4
, Issue.7
, pp. 487-499
-
-
Hervouet, E.1
Vallette, F.M.2
Cartron, P.F.3
-
18
-
-
0016692220
-
X inactivation, differentiation, and DNA methylation
-
Riggs AD. X inactivation, differentiation, and DNA methylation. Cytogenet. Cell Genet. 14(1), 9-25 (1975
-
(1975)
Cytogenet. Cell Genet
, vol.14
, Issue.1
, pp. 9-25
-
-
Riggs, A.D.1
-
19
-
-
0023701018
-
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells The carboxyl-Terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
-
Bestor T, Laudano A, Mattaliano R, Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-Terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J. Mol. Biol. 203(4), 971-983 (1988
-
(1988)
J. Mol. Biol
, vol.203
, Issue.4
, pp. 971-983
-
-
Bestor, T.1
Laudano, A.2
Mattaliano, R.3
Ingram, V.4
-
20
-
-
45449114804
-
The colorful history of active DNA demethylation
-
Ooi SK, Bestor TH. The colorful history of active DNA demethylation. Cell 133(7), 1145-1148 (2008
-
(2008)
Cell
, vol.133
, Issue.7
, pp. 1145-1148
-
-
Ooi, S.K.1
Bestor, T.H.2
-
21
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324(5929), 930-935 (2009
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
-
22
-
-
84877930005
-
DNA methylation and methylcytosine oxidation in cell fate decisions
-
Koh KP, Rao A. DNA methylation and methylcytosine oxidation in cell fate decisions. Curr. Opin. Cell. Biol. 25(2), 152-161 (2013
-
(2013)
Curr. Opin. Cell. Biol
, vol.25
, Issue.2
, pp. 152-161
-
-
Koh, K.P.1
Rao, A.2
-
23
-
-
84879235514
-
5-Hydroxymethylcytosine: Generation, fate, and genomic distribution
-
Shen L, Zhang Y. 5-Hydroxymethylcytosine: Generation, fate, and genomic distribution. Curr. Opin. Cell. Biol. 25(3), 289-296 (2013
-
(2013)
Curr. Opin. Cell. Biol
, vol.25
, Issue.3
, pp. 289-296
-
-
Shen, L.1
Zhang, Y.2
-
24
-
-
34250317798
-
A new pyrimidine base from bacteriophage nucleic acids
-
Wyatt GR, Cohen SS. A new pyrimidine base from bacteriophage nucleic acids. Nature 170(4338), 1072-1073 (1952
-
(1952)
Nature
, vol.170
, Issue.4338
, pp. 1072-1073
-
-
Wyatt, G.R.1
Cohen, S.S.2
-
25
-
-
0015298215
-
The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid
-
Penn NW, Suwalski R, O'Riley C, Bojanowski K, Yura R. The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid. Biochem. J. 126(4), 781-790 (1972
-
(1972)
Biochem. J.
, vol.126
, Issue.4
, pp. 781-790
-
-
Penn, N.W.1
Suwalski, R.2
O'Riley, C.3
Bojanowski, K.4
Yura, R.5
-
26
-
-
0017111827
-
5-Methylcytosine content in the vertebrate deoxyribonucleic acids: Species specificity
-
Kothari RM, Shankar V. 5-methylcytosine content in the vertebrate deoxyribonucleic acids: Species specificity. J. Mol. Evol. 7(4), 325-329 (1976
-
(1976)
J. Mol. Evol
, vol.7
, Issue.4
, pp. 325-329
-
-
Kothari, R.M.1
Shankar, V.2
-
27
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324(5929), 929-930 (2009
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
28
-
-
77749277177
-
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing
-
Huang Y, Pastor WA, Shen Y, Tahiliani M, Liu DR, Rao A. The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. PLoS ONE 5(1), e8888 (2010
-
(2010)
PLoS ONE
, vol.5
, Issue.1
-
-
Huang, Y.1
Pastor, W.A.2
Shen, Y.3
Tahiliani, M.4
Liu, D.R.5
Rao, A.6
-
29
-
-
77954061853
-
Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA
-
Nestor C, Ruzov A, Meehan R, Dunican D. Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA. Biotechniques 48(4), 317-319 (2010
-
(2010)
Biotechniques
, vol.48
, Issue.4
, pp. 317-319
-
-
Nestor, C.1
Ruzov, A.2
Meehan, R.3
Dunican, D.4
-
30
-
-
79959987448
-
5-Hydroxymethylcytosine, the sixth base of the genome
-
Munzel M, Globisch D, Carell T. 5-hydroxymethylcytosine, the sixth base of the genome. Angew. Chem. Int. Ed. Engl. 50(29), 6460-6468 (2011
-
(2011)
Angew. Chem. Int. Ed. Engl
, vol.50
, Issue.29
, pp. 6460-6468
-
-
Munzel, M.1
Globisch, D.2
Carell, T.3
-
31
-
-
34547528183
-
DNA methylation: Bisulphite modification and analysis
-
Clark SJ, Statham A, Stirzaker C, Molloy PL, Frommer M. DNA methylation: Bisulphite modification and analysis. Nat. Protoc. 1(5), 2353-2364 (2006
-
(2006)
Nat. Protoc
, vol.1
, Issue.5
, pp. 2353-2364
-
-
Clark, S.J.1
Statham, A.2
Stirzaker, C.3
Molloy, P.L.4
Frommer, M.5
-
32
-
-
0028096611
-
High sensitivity mapping of methylated cytosines
-
Clark SJ, Harrison J, Paul CL, Frommer M. High sensitivity mapping of methylated cytosines. Nucleic Acids Res. 22(15), 2990-2997 (1994
-
(1994)
Nucleic Acids Res
, vol.22
, Issue.15
, pp. 2990-2997
-
-
Clark, S.J.1
Harrison, J.2
Paul, C.L.3
Frommer, M.4
-
33
-
-
0034654669
-
MethyLight: A high-Throughput assay to measure DNA methylation
-
Eads CA, Danenberg KD, Kawakami K et al. MethyLight: A high-Throughput assay to measure DNA methylation. Nucleic Acids Res. 28(8), e32 (2000
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.8
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
-
34
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor WA, Pape UJ, Huang Y et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473(7347), 394-397 (2011
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
-
35
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M, Davies JJ, Wittig D et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat. Genet. 37(8), 853-862 (2005
-
(2005)
Nat. Genet
, vol.37
, Issue.8
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
-
36
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet. 39(4), 457-466 (2007
-
(2007)
Nat. Genet
, vol.39
, Issue.4
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
37
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz G, Branco MR, Seisenberger S et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473(7347), 398-402 (2011
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
-
38
-
-
84869075314
-
The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine
-
Huang Y, Pastor WA, Zepeda-Martinez JA, Rao A. The anti-CMS technique for genome-wide mapping of 5-hydroxymethylcytosine. Nat. Protoc. 7(10), 1897-1908 (2012
-
(2012)
Nat. Protoc
, vol.7
, Issue.10
, pp. 1897-1908
-
-
Huang, Y.1
Pastor, W.A.2
Zepeda-Martinez, J.A.3
Rao, A.4
-
39
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
Song CX, Szulwach KE, Fu Y et al. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat. Biotechnol. 29(1), 68-72 (2011
-
(2011)
Nat. Biotechnol
, vol.29
, Issue.1
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
-
40
-
-
79960127277
-
Tissue-specific distribution and dynamic changes of 5- hydroxymethylcytosine in mammalian genomes
-
Kinney SM, Chin HG, Vaisvila R et al. Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes. J. Biol. Chem. 286(28), 24685-24693 (2011
-
(2011)
J. Biol. Chem
, vol.286
, Issue.28
, pp. 24685-24693
-
-
Kinney, S.M.1
Chin, H.G.2
Vaisvila, R.3
-
41
-
-
84857891830
-
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
-
Nestor CE, Ottaviano R, Reddington J et al. Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Res. 22(3), 467-477 (2012
-
(2012)
Genome Res
, vol.22
, Issue.3
, pp. 467-477
-
-
Nestor, C.E.1
Ottaviano, R.2
Reddington, J.3
-
42
-
-
84861221693
-
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
-
Booth MJ, Branco MR, Ficz G et al. Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science 336(6083), 934-937 (2012
-
(2012)
Science
, vol.336
, Issue.6083
, pp. 934-937
-
-
Booth, M.J.1
Branco, M.R.2
Ficz, G.3
-
43
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu M, Hon GC, Szulwach KE et al. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 149(6), 1368-1380 (2012
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
-
44
-
-
53849113697
-
Discovery, biosyn thesis, and possible functions
-
Borst P, Sabatini R. Base J: Discovery, biosynthesis, and possible functions. Annu. Rev. Microbiol. 62, 235-251 (2008
-
(2008)
Annu. Rev. Microbiol
, vol.62
, pp. 235-251
-
-
Borst, P.1
Sabatini, R.2
Base, J.3
-
45
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion ES-cell selfrenewal and inner cell mass specification
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell selfrenewal and inner cell mass specification. Nature 466(7310), 1129-1133 (2010
-
(2010)
Nature
, vol.466
, Issue.7310
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
46
-
-
84860378636
-
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity
-
Freudenberg JM, Ghosh S, Lackford BL et al. Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity. Nucleic Acids Res. 40(8), 3364-3377 (2012
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.8
, pp. 3364-3377
-
-
Freudenberg, J.M.1
Ghosh, S.2
Lackford, B.L.3
-
47
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
Wu H, Zhang Y. Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev. 25(23), 2436-2452 (2011
-
(2011)
Genes Dev
, vol.25
, Issue.23
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
48
-
-
80051712275
-
Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond
-
Guo JU, Su Y, Zhong C, Ming GL, Song H. Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond. Cell Cycle 10(16), 2662-2668 (2011
-
(2011)
Cell Cycle
, vol.10
, Issue.16
, pp. 2662-2668
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
49
-
-
82655187149
-
S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance
-
Zhang J, Gao Q, Li P et al. S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance. Cell Res. 21(12), 1723-1739 (2011
-
(2011)
Cell Res
, vol.21
, Issue.12
, pp. 1723-1739
-
-
Zhang, J.1
Gao, Q.2
Li, P.3
-
50
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif J, Muto M, Takebayashi S et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450(7171), 908-912 (2007
-
(2007)
Nature
, vol.450
, Issue.7171
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.3
-
51
-
-
53649089723
-
The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
-
Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature 455(7214), 826-829 (2008
-
(2008)
Nature
, vol.455
, Issue.7214
, pp. 826-829
-
-
Hashimoto, H.1
Horton, J.R.2
Zhang, X.3
Bostick, M.4
Jacobsen, S.E.5
Cheng, X.6
-
52
-
-
33847055935
-
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
-
Valinluck V, Sowers LC. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res. 67(3), 946-950 (2007
-
(2007)
Cancer Res
, vol.67
, Issue.3
, pp. 946-950
-
-
Valinluck, V.1
Sowers, L.C.2
-
53
-
-
84860221291
-
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
-
Hashimoto H, Liu Y, Upadhyay AK et al. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Res. 40(11), 4841-4849 (2012
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.11
, pp. 4841-4849
-
-
Hashimoto, H.1
Liu, Y.2
Upadhyay, A.K.3
-
54
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue A, Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 334(6053), 194 (2011
-
(2011)
Science
, vol.334
, Issue.6053
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
55
-
-
79959431845
-
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain
-
Frauer C, Hoffmann T, Bultmann S et al. Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. PLoS ONE 6(6), e21306 (2011
-
(2011)
PLoS ONE
, vol.6
, Issue.6
-
-
Frauer, C.1
Hoffmann, T.2
Bultmann, S.3
-
56
-
-
84879386819
-
Regulation of lineage specific DNA hypomethylation in mouse trophectoderm
-
Oda M, Oxley D, Dean W, Reik W. Regulation of lineage specific DNA hypomethylation in mouse trophectoderm. PLoS ONE 8(6), e68846 (2013
-
(2013)
PLoS ONE
, vol.8
, Issue.6
-
-
Oda, M.1
Oxley, D.2
Dean, W.3
Reik, W.4
-
57
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, Li BZ, Li Z et al. Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333(6047), 1303-1307 (2011
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
-
58
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S, Shen L, Dai Q et al. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333(6047), 1300-1303 (2011
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
-
59
-
-
84862681459
-
Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing
-
Schiesser S, Hackner B, Pfaffeneder T et al. Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing. Angew. Chem. Int. Ed. Engl. 51(26), 6516-6520 (2012
-
(2012)
Angew. Chem. Int. Ed. Engl
, vol.51
, Issue.26
, pp. 6516-6520
-
-
Schiesser, S.1
Hackner, B.2
Pfaffeneder, T.3
-
60
-
-
19744376088
-
Genes of the thymidine salvage pathway: Thymine-7-hydroxylase from a Rhodotorula glutinis cDNA library and iso-orotate decarboxylase from Neurospora crassa
-
Smiley JA, Kundracik M, Landfried DA, Barnes VR Sr, Axhemi AA. Genes of the thymidine salvage pathway: Thymine-7-hydroxylase from a Rhodotorula glutinis cDNA library and iso-orotate decarboxylase from Neurospora crassa. Biochim. Biophys. Acta 1723(1-3), 256-264 (2005
-
(2005)
Biochim. Biophys. Acta
, vol.1723
, Issue.1-3
, pp. 256-264
-
-
Smiley, J.A.1
Kundracik, M.2
Landfried, D.A.3
Barnes Sr., V.R.4
Axhemi, A.A.5
-
61
-
-
0034687768
-
An unexpectedly high excision capacity for mispaired 5- hydroxymethyluracil in human cell extracts
-
Rusmintratip V, Sowers LC. An unexpectedly high excision capacity for mispaired 5-hydroxymethyluracil in human cell extracts. Proc. Natl Acad. Sci. USA 97(26), 14183-14187 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, Issue.26
, pp. 14183-14187
-
-
Rusmintratip, V.1
Sowers, L.C.2
-
62
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S, Xu J, Sannai M et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146(1), 67-79 (2011
-
(2011)
Cell
, vol.146
, Issue.1
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
-
63
-
-
84869044795
-
Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: Its structural basis and implications for active DNA demethylation
-
Hashimoto H, Hong S, Bhagwat AS, Zhang X, Cheng X. Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: Its structural basis and implications for active DNA demethylation. Nucleic Acids Res. 40(20), 10203-10214 (2012
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.20
, pp. 10203-10214
-
-
Hashimoto, H.1
Hong, S.2
Bhagwat, A.S.3
Zhang, X.4
Cheng, X.5
-
64
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK. Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming. J. Biol. Chem. 279(50), 52353-52360 (2004
-
(2004)
J. Biol. Chem
, vol.279
, Issue.50
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
65
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp C, Dean W, Feng S et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 463(7284), 1101-1105 (2010
-
(2010)
Nature
, vol.463
, Issue.7284
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
-
66
-
-
84865329141
-
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation
-
Nabel CS, Jia H, Ye Y et al. AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation. Nat. Chem. Biol. 8(9), 751-758 (2012
-
(2012)
Nat. Chem. Biol
, vol.8
, Issue.9
, pp. 751-758
-
-
Nabel, C.S.1
Jia, H.2
Ye, Y.3
-
67
-
-
84860388901
-
Active DNA demethylation by oxidation and repair
-
Gong Z, Zhu JK. Active DNA demethylation by oxidation and repair. Cell Res. 21(12), 1649-1651 (2011
-
(2011)
Cell Res
, vol.21
, Issue.12
, pp. 1649-1651
-
-
Gong, Z.1
Zhu, J.K.2
-
68
-
-
84865061978
-
Genomewide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase
-
Raiber EA, Beraldi D, Ficz G et al. Genomewide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol. 13(8), R69 (2012
-
(2012)
Genome Biol
, vol.13
, Issue.8
-
-
Raiber, E.A.1
Beraldi, D.2
Ficz, G.3
-
69
-
-
84862776719
-
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine- modified DNA
-
Zhang L, Lu X, Lu J et al. Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat. Chem. Biol. 8(4), 328-330 (2012
-
(2012)
Nat. Chem. Biol
, vol.8
, Issue.4
, pp. 328-330
-
-
Zhang, L.1
Lu, X.2
Lu, J.3
-
70
-
-
84876946045
-
Genome-wide analysis reveals TET-And TDG-dependent 5-methylcytosine oxidation dynamics
-
Shen L, Wu H, Diep D et al. Genome-wide analysis reveals TET-And TDG-dependent 5-methylcytosine oxidation dynamics. Cell 153(3), 692-706 (2013
-
(2013)
Cell
, vol.153
, Issue.3
, pp. 692-706
-
-
Shen, L.1
Wu, H.2
Diep, D.3
-
71
-
-
84876907152
-
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming
-
Song CX, Szulwach KE, Dai Q et al. Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell 153(3), 678-691 (2013
-
(2013)
Cell
, vol.153
, Issue.3
, pp. 678-691
-
-
Song, C.X.1
Szulwach, K.E.2
Dai, Q.3
-
72
-
-
82655187105
-
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development
-
Inoue A, Shen L, Dai Q, He C, Zhang Y. Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Res. 21(12), 1670-1676 (2011
-
(2011)
Cell Res
, vol.21
, Issue.12
, pp. 1670-1676
-
-
Inoue, A.1
Shen, L.2
Dai, Q.3
He, C.4
Zhang, Y.5
-
73
-
-
77954362183
-
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
-
Jin SG, Kadam S, Pfeifer GP. Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine. Nucleic Acids Res. 38(11), e125 (2010
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.11
-
-
Jin, S.G.1
Kadam, S.2
Pfeifer, G.P.3
-
74
-
-
4043112183
-
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2
-
Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res. 32(14), 4100-4108 (2004
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.14
, pp. 4100-4108
-
-
Valinluck, V.1
Tsai, H.H.2
Rogstad, D.K.3
Burdzy, A.4
Bird, A.5
Sowers, L.C.6
-
75
-
-
84455167621
-
Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim O, Li R, Hung JH et al. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147(7), 1498-1510 (2011
-
(2011)
Cell
, vol.147
, Issue.7
, pp. 1498-1510
-
-
Yildirim, O.1
Li, R.2
Hung, J.H.3
-
76
-
-
84871563384
-
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
Mellen M, Ayata P, Dewell S, Kriaucionis S, Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151(7), 1417-1430 (2012
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1417-1430
-
-
Mellen, M.1
Ayata, P.2
Dewell, S.3
Kriaucionis, S.4
Heintz, N.5
-
77
-
-
84874771985
-
Dynamic readers for 5-(hydroxy) methylcytosine and its oxidized derivatives
-
Spruijt CG, Gnerlich F, Smits AH et al. Dynamic readers for 5-(hydroxy) methylcytosine and its oxidized derivatives. Cell 152(5), 1146-1159 (2013
-
(2013)
Cell
, vol.152
, Issue.5
, pp. 1146-1159
-
-
Spruijt, C.G.1
Gnerlich, F.2
Smits, A.H.3
-
78
-
-
0035893358
-
Lashings of DNA methylation, forkfuls of chromatin remodeling
-
Meehan RR, Pennings S, Stancheva I. Lashings of DNA methylation, forkfuls of chromatin remodeling. Genes Dev. 15(24), 3231-3236 (2001
-
(2001)
Genes Dev
, vol.15
, Issue.24
, pp. 3231-3236
-
-
Meehan, R.R.1
Pennings, S.2
Stancheva, I.3
-
79
-
-
0035890090
-
Lsh, a member of the SNF2 family, is required for genome-wide methylation
-
Dennis K, Fan T, Geiman T, Yan Q, Muegge K. Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev. 15(22), 2940-2944 (2001
-
(2001)
Genes Dev
, vol.15
, Issue.22
, pp. 2940-2944
-
-
Dennis, K.1
Fan, T.2
Geiman, T.3
Yan, Q.4
Muegge, K.5
-
80
-
-
79960249232
-
Genomic mapping of 5-hydroxymethylcytosine in the human brain
-
Jin SG, Wu X, Li AX, Pfeifer GP. Genomic mapping of 5- hydroxymethylcytosine in the human brain. Nucleic Acids Res. 39(12), 5015-5024 (2011
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.12
, pp. 5015-5024
-
-
Jin, S.G.1
Wu, X.2
Li, A.X.3
Pfeifer, G.P.4
-
81
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K, Christensen J, Pedersen MT et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473(7347), 343-348 (2011
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
-
82
-
-
79959859654
-
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells
-
Szulwach KE, Li X, Li Y et al. Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet. 7(6), e1002154 (2011
-
(2011)
PLoS Genet
, vol.7
, Issue.6
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
-
83
-
-
84880530231
-
Ten-eleven translocation 1 (tet1) is regulated by O-linked N-Acetylglucosamine transferase (OGT) for target gene repression in mouse embryonic stem cells
-
Shi FT, Kim H, Lu W et al. Ten-eleven translocation 1 (tet1) is regulated by O-linked N-Acetylglucosamine transferase (OGT) for target gene repression in mouse embryonic stem cells. J. Biol. Chem. 288(29), 20776-20784 (2013
-
(2013)
J. Biol. Chem
, vol.288
, Issue.29
, pp. 20776-20784
-
-
Shi, F.T.1
Kim, H.2
Lu, W.3
-
84
-
-
84875218124
-
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
-
Deplus R, Delatte B, Schwinn MK et al. TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS. EMBO J. 32(5), 645-655 (2013
-
(2013)
EMBO J.
, vol.32
, Issue.5
, pp. 645-655
-
-
Deplus, R.1
Delatte, B.2
Schwinn, M.K.3
-
85
-
-
84874266225
-
Tet proteins connect the O-linked N-Acetylglucosamine transferase OGT to chromatin in embryonic stem cells
-
Vella P, Scelfo A, Jammula S et al. Tet proteins connect the O-linked N-Acetylglucosamine transferase OGT to chromatin in embryonic stem cells. Mol. Cell 49(4), 645-656 (2013
-
(2013)
Mol. Cell
, vol.49
, Issue.4
, pp. 645-656
-
-
Vella, P.1
Scelfo, A.2
Jammula, S.3
-
86
-
-
84872953223
-
TET2 promotes histone O-GlcNAcylation during gene transcription
-
Chen Q, Chen Y, Bian C, Fujiki R, Yu X. TET2 promotes histone O-GlcNAcylation during gene transcription. Nature 493(7433), 561-564 (2013
-
(2013)
Nature
, vol.493
, Issue.7433
, pp. 561-564
-
-
Chen, Q.1
Chen, Y.2
Bian, C.3
Fujiki, R.4
Yu, X.5
-
87
-
-
79959209733
-
5-hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
-
Stroud H, Feng S, Morey Kinney S, Pradhan S, Jacobsen SE. 5-hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biol. 12(6), R54 (2011
-
(2011)
Genome Biol
, vol.12
, Issue.6
-
-
Stroud, H.1
Feng, S.2
Morey Kinney, S.3
Pradhan, S.4
Jacobsen, S.E.5
-
88
-
-
27744566304
-
From DNA sequence analysis to modeling replication in the human genome
-
Brodie Of
-
Brodie Of Brodie EB, Nicolay S, Touchon M et al. From DNA sequence analysis to modeling replication in the human genome. Phys. Rev. Lett. 94(24), 248103 (2005
-
(2005)
Phys. Rev. Lett
, vol.94
, Issue.24
, pp. 248103
-
-
Brodie, E.B.1
Nicolay, S.2
Touchon, M.3
-
89
-
-
22244455429
-
Replication-Associated strand asymmetries in mammalian genomes: Toward detection of replication origins
-
Touchon M, Nicolay S, Audit B et al. Replication-Associated strand asymmetries in mammalian genomes: Toward detection of replication origins. Proc. Natl Acad. Sci. USA 102(28), 9836-9841 (2005
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.28
, pp. 9836-9841
-
-
Touchon, M.1
Nicolay, S.2
Audit, B.3
-
90
-
-
34548396264
-
Human gene organization driven by the coordination of replication and transcription
-
Huvet M, Nicolay S, Touchon M et al. Human gene organization driven by the coordination of replication and transcription. Genome Res. 17(9), 1278-1285 (2007
-
(2007)
Genome Res
, vol.17
, Issue.9
, pp. 1278-1285
-
-
Huvet, M.1
Nicolay, S.2
Touchon, M.3
-
91
-
-
84255200412
-
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
-
Jin SG, Jiang Y, Qiu R et al. 5-hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res. 71(24), 7360-7365 (2011
-
(2011)
Cancer Res
, vol.71
, Issue.24
, pp. 7360-7365
-
-
Jin, S.G.1
Jiang, Y.2
Qiu, R.3
-
92
-
-
84879663784
-
Global epigenomic reconfiguration during mammalian brain development
-
Lister R, Mukamel EA, Nery JR et al. Global epigenomic reconfiguration during mammalian brain development. Science 341(6146), 1237905 (2013
-
(2013)
Science
, vol.341
, Issue.6146
, pp. 1237905
-
-
Lister, R.1
Mukamel, E.A.2
Nery, J.R.3
-
93
-
-
84878843769
-
Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver
-
Thomson JP, Hunter JM, Lempiainen H et al. Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver. Nucleic Acids Res. 41(11), 5639-5654 (2013
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.11
, pp. 5639-5654
-
-
Thomson, J.P.1
Hunter, J.M.2
Lempiainen, H.3
-
94
-
-
84866847877
-
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome
-
Thomson JP, Lempiainen H, Hackett JA et al. Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome. Genome Biol. 13(10), R93 (2012
-
(2012)
Genome Biol
, vol.13
, Issue.10
-
-
Thomson, J.P.1
Lempiainen, H.2
Hackett, J.A.3
-
95
-
-
0015142880
-
Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-Acetylaminofluorene
-
Peraino C, Fry RJ, Staffeldt E. Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2- Acetylaminofluorene. Cancer Res. 31(10), 1506-1512 (1971
-
(1971)
Cancer Res
, vol.31
, Issue.10
, pp. 1506-1512
-
-
Peraino, C.1
Fry, R.J.2
Staffeldt, E.3
-
96
-
-
0020335340
-
Morphological classification of mouse liver tumors based on biological characteristics
-
Becker FF. Morphological classification of mouse liver tumors based on biological characteristics. Cancer Res. 42(10), 3918-3923 (1982
-
(1982)
Cancer Res
, vol.42
, Issue.10
, pp. 3918-3923
-
-
Becker, F.F.1
-
97
-
-
33744802237
-
Phenobarbital induces progressive patterns of GC-rich and gene-specific altered DNA methylation in the liver of tumor-prone B6C3F1 mice
-
Bachman AN, Phillips JM, Goodman JI. Phenobarbital induces progressive patterns of GC-rich and gene-specific altered DNA methylation in the liver of tumor-prone B6C3F1 mice. Toxicol. Sci. 91(2), 393-405 (2006
-
(2006)
Toxicol. Sci
, vol.91
, Issue.2
, pp. 393-405
-
-
Bachman, A.N.1
Phillips, J.M.2
Goodman, J.I.3
-
98
-
-
0035936026
-
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of betacatenin-mutated mouse liver tumors
-
Aydinlik H, Nguyen TD, Moennikes O, Buchmann A, Schwarz M. Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of betacatenin-mutated mouse liver tumors. Oncogene 20(53), 7812-7816 (2001
-
(2001)
Oncogene
, vol.20
, Issue.53
, pp. 7812-7816
-
-
Aydinlik, H.1
Nguyen, T.D.2
Moennikes, O.3
Buchmann, A.4
Schwarz, M.5
-
99
-
-
0034117990
-
Paradoxical effects of phenobarbital on mouse hepatocarcinogenesis
-
Lee GH. Paradoxical effects of phenobarbital on mouse hepatocarcinogenesis. Toxicol. Pathol. 28(2), 215-225 (2000
-
(2000)
Toxicol. Pathol
, vol.28
, Issue.2
, pp. 215-225
-
-
Lee, G.H.1
-
100
-
-
84877630473
-
Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling
-
Mutoh S, Sobhany M, Moore R et al. Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling. Sci. Signal. 6(274), ra31 (2013
-
(2013)
Sci. Signal
, vol.6
, Issue.274
-
-
Mutoh, S.1
Sobhany, M.2
Moore, R.3
-
101
-
-
84883499033
-
Cigarette smoking and DNA methylation
-
Lee KW, Pausova Z. Cigarette smoking and DNA methylation. Front. Genet. 4, 132 (2013
-
(2013)
Front. Genet
, vol.4
, Issue.132
-
-
Lee, K.W.1
Pausova, Z.2
-
102
-
-
84856058152
-
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
-
Haffner MC, Chaux A, Meeker AK et al. Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget 2(8), 627-637 (2011
-
(2011)
Oncotarget
, vol.2
, Issue.8
, pp. 627-637
-
-
Haffner, M.C.1
Chaux, A.2
Meeker, A.K.3
-
103
-
-
77954661906
-
DNA hypomethylation in cancer cells
-
Ehrlich M. DNA hypomethylation in cancer cells. Epigenomics 1(2), 239-259 (2009
-
(2009)
Epigenomics
, vol.1
, Issue.2
, pp. 239-259
-
-
Ehrlich, M.1
-
104
-
-
80052933429
-
DNA demethylation dynamics
-
Bhutani N, Burns DM, Blau HM. DNA demethylation dynamics. Cell 146(6), 866-872 (2011
-
(2011)
Cell
, vol.146
, Issue.6
, pp. 866-872
-
-
Bhutani, N.1
Burns, D.M.2
Blau, H.M.3
-
105
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal K, Jin SG, Pfeifer GP, Szabo PE. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl Acad. Sci. USA 108(9), 3642-3647 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.9
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
106
-
-
79952713567
-
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
Wossidlo M, Nakamura T, Lepikhov K et al. 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat. Commun. 2, 241 (2011
-
(2011)
Nat. Commun
, vol.2
, Issue.241
-
-
Wossidlo, M.1
Nakamura, T.2
Lepikhov, K.3
-
107
-
-
0037099537
-
LCX, leukemiaassociated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23
-
Ono R, Taki T, Taketani T, Taniwaki M, Kobayashi H, Hayashi Y. LCX, leukemiaassociated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res. 62(14), 4075-4080 (2002
-
(2002)
Cancer Res
, vol.62
, Issue.14
, pp. 4075-4080
-
-
Ono, R.1
Taki, T.2
Taketani, T.3
Taniwaki, M.4
Kobayashi, H.5
Hayashi, Y.6
-
108
-
-
0037350661
-
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11) q22;q23
-
Lorsbach RB, Moore J, Mathew S, Raimondi SC, Mukatira ST, Downing Jr. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 17(3), 637-641 (2003
-
(2003)
Leukemia
, vol.17
, Issue.3
, pp. 637-641
-
-
Lorsbach, R.B.1
Moore, J.2
Mathew, S.3
Raimondi, S.C.4
Mukatira, S.T.5
Downing, J.R.6
-
109
-
-
84866908544
-
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases
-
Hsu CH, Peng KL, Kang ML et al. TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases. Cell Rep. 2(3), 568-579 (2012
-
(2012)
Cell Rep
, vol.2
, Issue.3
, pp. 568-579
-
-
Hsu, C.H.1
Peng, K.L.2
Kang, M.L.3
-
110
-
-
84879001094
-
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis
-
Sun M, Song CX, Huang H et al. HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc. Natl Acad. Sci. USA 110(24), 9920-9925 (2013
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, Issue.24
, pp. 9920-9925
-
-
Sun, M.1
Song, C.X.2
Huang, H.3
-
111
-
-
84877336241
-
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1
-
Liu C, Liu L, Chen X et al. Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1. PLoS ONE 8(5), e62828 (2013
-
(2013)
PLoS ONE
, vol.8
, Issue.5
-
-
Liu, C.1
Liu, L.2
Chen, X.3
-
112
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
Lian CG, Xu Y, Ceol C et al. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 150(6), 1135-1146 (2012
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1135-1146
-
-
Lian, C.G.1
Xu, Y.2
Ceol, C.3
-
113
-
-
84886808164
-
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer
-
Bhattacharyya S, Yu Y, Suzuki M et al. Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer. Nucleic Acids Res. 41(16), e157 (2013
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.16
-
-
Bhattacharyya, S.1
Yu, Y.2
Suzuki, M.3
-
114
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood LD, Parsons DW, Jones S et al. The genomic landscapes of human breast and colorectal cancers. Science 318(5853), 1108-1113 (2007
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
-
115
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
Sjoblom T, Jones S, Wood LD et al. The consensus coding sequences of human breast and colorectal cancers. Science 314(5797), 268-274 (2006
-
(2006)
Science
, vol.314
, Issue.5797
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
-
116
-
-
77955660663
-
Diverse somatic mutation patterns and pathway alterations in human cancers
-
Kan Z, Jaiswal BS, Stinson J et al. Diverse somatic mutation patterns and pathway alterations in human cancers. Nature 466(7308), 869-873 (2010
-
(2010)
Nature
, vol.466
, Issue.7308
, pp. 869-873
-
-
Kan, Z.1
Jaiswal, B.S.2
Stinson, J.3
-
117
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger MF, Lawrence MS, Demichelis F et al. The genomic complexity of primary human prostate cancer. Nature 470(7333), 214-220 (2011
-
(2011)
Nature
, vol.470
, Issue.7333
, pp. 214-220
-
-
Berger, M.F.1
Lawrence, M.S.2
Demichelis, F.3
-
118
-
-
67651065502
-
Genetic characterization of TET1 TET2, and TET3 alterations in myeloid malignancies
-
Abdel-Wahab O, Mullally A, Hedvat C et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood 114(1), 144-147 (2009
-
(2009)
Blood
, vol.114
, Issue.1
, pp. 144-147
-
-
Abdel-Wahab, O.1
Mullally, A.2
Hedvat, C.3
-
120
-
-
67650588639
-
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/ myeloproliferative neoplasms
-
Jankowska AM, Szpurka H, Tiu RV et al. Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/ myeloproliferative neoplasms. Blood 113(25), 6403-6410 (2009
-
(2009)
Blood
, vol.113
, Issue.25
, pp. 6403-6410
-
-
Jankowska, A.M.1
Szpurka, H.2
Tiu, R.V.3
-
121
-
-
77956237515
-
Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1
-
Kohlmann A, Grossmann V, Klein HU et al. Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1. J. Clin. Oncol. 28(24), 3858-3865 (2010
-
(2010)
J. Clin. Oncol
, vol.28
, Issue.24
, pp. 3858-3865
-
-
Kohlmann, A.1
Grossmann, V.2
Klein, H.U.3
-
122
-
-
67649876132
-
Acquired mutations in TET2 are common in myelodysplastic syndromes
-
Langemeijer SM, Kuiper RP, Berends M et al. Acquired mutations in TET2 are common in myelodysplastic syndromes. Nat. Genet. 41(7), 838-842 (2009
-
(2009)
Nat. Genet
, vol.41
, Issue.7
, pp. 838-842
-
-
Langemeijer, S.M.1
Kuiper, R.P.2
Berends, M.3
-
123
-
-
67650924270
-
Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
-
Tefferi A, Lim KH, Abdel-Wahab O et al. Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML. Leukemia 23(7), 1343-1345 (2009
-
(2009)
Leukemia
, vol.23
, Issue.7
, pp. 1343-1345
-
-
Tefferi, A.1
Lim, K.H.2
Abdel-Wahab, O.3
-
124
-
-
79960062301
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron C, Couronne L, Della Valle V et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20(1), 25-38 (2011
-
(2011)
Cancer Cell
, vol.20
, Issue.1
, pp. 25-38
-
-
Quivoron, C.1
Couronne, L.2
Della Valle, V.3
-
125
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh KP, Yabuuchi A, Rao S et al. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8(2), 200-213 (2011
-
(2011)
Cell Stem Cell
, vol.8
, Issue.2
, pp. 200-213
-
-
Koh, K.P.1
Yabuuchi, A.2
Rao, S.3
-
126
-
-
80052284526
-
Ten-eleventranslocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
-
Ko M, Bandukwala HS, An J et al. Ten-eleventranslocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc. Natl Acad. Sci. USA 108(35), 14566-14571 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.35
, pp. 14566-14571
-
-
Ko, M.1
Bandukwala, H.S.2
An, J.3
-
127
-
-
80052285127
-
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
-
Li Z, Cai X, Cai CL et al. Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies. Blood 118(17), 4509-4518 (2011
-
(2011)
Blood
, vol.118
, Issue.17
, pp. 4509-4518
-
-
Li, Z.1
Cai, X.2
Cai, C.L.3
-
128
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio K, Reavie L, Shih A et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20(1), 11-24 (2011
-
(2011)
Cancer Cell
, vol.20
, Issue.1
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
-
129
-
-
79952741730
-
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
-
Reitman ZJ, Jin G, Karoly ED et al. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc. Natl Acad. Sci. USA 108(8), 3270-3275 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.8
, pp. 3270-3275
-
-
Reitman, Z.J.1
Jin, G.2
Karoly, E.D.3
-
130
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
Xu W, Yang H, Liu Y et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 19(1), 17-30 (2011
-
(2011)
Cancer Cell
, vol.19
, Issue.1
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
-
131
-
-
72049125350
-
Cancerassociated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S et al. Cancerassociated IDH1 mutations produce 2-hydroxyglutarate. Nature 462(7274), 739-744 (2009
-
(2009)
Nature
, vol.462
, Issue.7274
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
132
-
-
77649305610
-
The common feature of leukemia-Associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
-
Ward PS, Patel J, Wise DR et al. The common feature of leukemia-Associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell 17(3), 225-234 (2010
-
(2010)
Cancer Cell
, vol.17
, Issue.3
, pp. 225-234
-
-
Ward, P.S.1
Patel, J.2
Wise, D.R.3
-
133
-
-
79955547561
-
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
-
Chowdhury R, Yeoh KK, Tian YM et al. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep. 12(5), 463-469 (2011
-
(2011)
EMBO Rep
, vol.12
, Issue.5
, pp. 463-469
-
-
Chowdhury, R.1
Yeoh, K.K.2
Tian, Y.M.3
-
134
-
-
84862776918
-
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
-
Koivunen P, Lee S, Duncan CG et al. Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature 483(7390), 484-488 (2012
-
(2012)
Nature
, vol.483
, Issue.7390
, pp. 484-488
-
-
Koivunen, P.1
Lee, S.2
Duncan, C.G.3
-
135
-
-
84875496294
-
R-2-Hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible
-
Losman JA, Looper RE, Koivunen P et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science 339(6127), 1621-1625 (2013
-
(2013)
Science
, vol.339
, Issue.6127
, pp. 1621-1625
-
-
Losman, J.A.1
Looper, R.E.2
Koivunen, P.3
-
136
-
-
76549109434
-
Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias
-
Abdel-Wahab O, Manshouri T, Patel J et al. Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias. Cancer Res. 70(2), 447-452 (2010
-
(2010)
Cancer Res
, vol.70
, Issue.2
, pp. 447-452
-
-
Abdel-Wahab, O.1
Manshouri, T.2
Patel, J.3
-
137
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X et al. An integrated genomic analysis of human glioblastoma multiforme. Science 321(5897), 1807-1812 (2008
-
(2008)
Science
, vol.321
, Issue.5897
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
138
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H, Parsons DW, Jin G et al. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 360(8), 765-773 (2009
-
(2009)
N. Engl. J. Med
, vol.360
, Issue.8
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
139
-
-
67449099808
-
Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers
-
Kang MR, Kim MS, Oh JE et al. Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers. Int. J. Cancer 125(2), 353-355 (2009
-
(2009)
Int. J. Cancer
, vol.125
, Issue.2
, pp. 353-355
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
-
140
-
-
77949262337
-
Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer
-
Murugan AK, Bojdani E, Xing M. Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer. Biochem. Biophys. Res. Commun. 393(3), 555-559 (2010
-
(2010)
Biochem. Biophys. Res. Commun
, vol.393
, Issue.3
, pp. 555-559
-
-
Murugan, A.K.1
Bojdani, E.2
Xing, M.3
-
141
-
-
84879418850
-
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
-
Wang P, Dong Q, Zhang C et al. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene 32(25), 3091-3100 (2013
-
(2013)
Oncogene
, vol.32
, Issue.25
, pp. 3091-3100
-
-
Wang, P.1
Dong, Q.2
Zhang, C.3
-
142
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr H, Weisenberger DJ, Diefes K et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17(5), 510-522 (2010
-
(2010)
Cancer Cell
, vol.17
, Issue.5
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
143
-
-
84864463122
-
Low values of 5-hydroxymethylcytosine (5hmc) the "sixth base," are associated with anaplasia in human brain tumors
-
Kraus TF, Globisch D, Wagner M et al. Low values of 5- hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors. Int. J. Cancer 131(7), 1577-1590 (2012
-
(2012)
Int. J. Cancer
, vol.131
, Issue.7
, pp. 1577-1590
-
-
Kraus, T.F.1
Globisch, D.2
Wagner, M.3
-
144
-
-
84864120277
-
Nuclear exclusion of TET1 is associated with loss of 5- hydroxymethylcytosine in IDH1 wild-Type gliomas
-
Muller T, Gessi M, Waha A et al. Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-Type gliomas. Am. J. Pathol. 181(2), 675-683 (2012
-
(2012)
Am. J. Pathol
, vol.181
, Issue.2
, pp. 675-683
-
-
Muller, T.1
Gessi, M.2
Waha, A.3
-
145
-
-
84864053192
-
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma
-
Orr BA, Haffner MC, Nelson WG, Yegnasubramanian S, Eberhart CG. Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma. PLoS ONE 7(7), e41036 (2012
-
(2012)
PLoS ONE
, vol.7
, Issue.7
-
-
Orr, B.A.1
Haffner, M.C.2
Nelson, W.G.3
Yegnasubramanian, S.4
Eberhart, C.G.5
-
146
-
-
0035834409
-
A conserved family of prolyl-4-hydroxylases that modify HIF
-
Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science 294(5545), 1337-1340 (2001
-
(2001)
Science
, vol.294
, Issue.5545
, pp. 1337-1340
-
-
Bruick, R.K.1
McKnight, S.L.2
-
147
-
-
32844454603
-
Histone demethylation by a family of JmjC domain-containing proteins
-
Tsukada Y, Fang J, Erdjument-Bromage H et al. Histone demethylation by a family of JmjC domain-containing proteins. Nature 439(7078), 811-816 (2006
-
(2006)
Nature
, vol.439
, Issue.7078
, pp. 811-816
-
-
Tsukada, Y.1
Fang, J.2
Erdjument-Bromage, H.3
-
148
-
-
0034602950
-
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
-
Baysal BE, Ferrell RE, Willett-Brozick JE et al. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 287(5454), 848-851 (2000
-
(2000)
Science
, vol.287
, Issue.5454
, pp. 848-851
-
-
Baysal, B.E.1
Ferrell, R.E.2
Willett-Brozick, J.E.3
-
149
-
-
69549088424
-
SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma
-
Hao HX, Khalimonchuk O, Schraders M et al. SDH5, a gene required for flavination of succinate dehydrogenase, is mutated in paraganglioma. Science 325(5944), 1139-1142 (2009
-
(2009)
Science
, vol.325
, Issue.5944
, pp. 1139-1142
-
-
Hao, H.X.1
Khalimonchuk, O.2
Schraders, M.3
-
150
-
-
77950342008
-
SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma
-
Bayley JP, Kunst HP, Cascon A et al. SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma. Lancet Oncol. 11(4), 366-372 (2010
-
(2010)
Lancet Oncol
, vol.11
, Issue.4
, pp. 366-372
-
-
Bayley, J.P.1
Kunst, H.P.2
Cascon, A.3
-
151
-
-
18544365990
-
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer
-
Tomlinson IP, Alam NA, Rowan AJ et al. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat. Genet. 30(4), 406-410 (2002
-
(2002)
Nat. Genet
, vol.30
, Issue.4
, pp. 406-410
-
-
Tomlinson, I.P.1
Alam, N.A.2
Rowan, A.J.3
-
152
-
-
84878969599
-
SDH mutations establish a hypermethylator phenotype in paraganglioma
-
Letouze E, Martinelli C, Loriot C et al. SDH mutations establish a hypermethylator phenotype in paraganglioma. Cancer Cell 23(6), 739-752 (2013
-
(2013)
Cancer Cell
, vol.23
, Issue.6
, pp. 739-752
-
-
Letouze, E.1
Martinelli, C.2
Loriot, C.3
-
153
-
-
84862632865
-
Inhibition of alpha-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
-
Xiao M, Yang H, Xu W et al. Inhibition of alpha-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes Dev. 26(12), 1326-1338 (2012
-
(2012)
Genes Dev
, vol.26
, Issue.12
, pp. 1326-1338
-
-
Xiao, M.1
Yang, H.2
Xu, W.3
-
154
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366(10), 883-892 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.10
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
-
155
-
-
77955633914
-
Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip
-
Thirlwell C, Eymard M, Feber A et al. Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip. Methods 52(3), 248-254 (2010
-
(2010)
Methods
, vol.52
, Issue.3
, pp. 248-254
-
-
Thirlwell, C.1
Eymard, M.2
Feber, A.3
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