Phenobarbital induces progressive patterns of GC-rich and gene-specific altered DNA methylation in the liver of tumor-prone B6C3F1 mice

Toxicological Sciences

Volumn 91, Issue 2, 2006, Pages 393-405

  Bachman, Ammie N ^a   Phillips, Jennifer M ^b   Goodman, Jay I ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b Michigan State University   (United States)

Author keywords

B6C3F1; DNA methylation; Epigenetic; Ha ras; Liver; Phenobarbital

Indexed keywords

DNA; GUANINE NUCLEOTIDE; PHENOBARBITAL; PYRIMIDINE NUCLEOTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ELECTROPHORESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA ISOLATION; DNA METHYLATION; EPIGENETICS; GENE EXPRESSION; GENE SEQUENCE; LIVER CARCINOGENESIS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE H RAS; REAL TIME POLYMERASE CHAIN REACTION; SEPARATION TECHNIQUE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE;

ANIMALS; CARCINOGENS; DNA METHYLATION; GC RICH SEQUENCE; GENE EXPRESSION REGULATION; GENES, RAS; GENETIC PREDISPOSITION TO DISEASE; KIDNEY; LIVER; LIVER NEOPLASMS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; PHENOBARBITAL; PROMOTER REGIONS (GENETICS);

RODENTIA;

EID: 33744802237     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfj155     Document Type: Article

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