Nuclear exclusion of TET1 is associated with loss of 5- hydroxymethylcytosine in IDH1 wild-type gliomas

American Journal of Pathology

Volumn 181, Issue 2, 2012, Pages 675-683

  Waha, Andreas ^a   Müller, Tim ^a   Gessi, Marco ^a   Waha, Anke ^a   Isselstein, Lukas Jan ^a   Luxen, Daniel ^a   Freihoff, Dorothee ^a   Freihoff, Johannes ^a   Becker, Albert ^a   Simon, Matthias ^b   Hammes, Jennifer ^a   Denkhaus, Dorota ^a   Zur Mühlen, Anja ^a   Pietsch, Torsten ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYGLUTARIC ACID; 5 HYDROXYMETHYLCYTOSINE; ISOCITRATE DEHYDROGENASE 1; PROTEIN; TET1 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CELL NUCLEUS; CELLULAR DISTRIBUTION; CYTOPLASM; ENZYME INHIBITION; FEMALE; GENE MUTATION; GLIOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; METABOLITE; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

5-METHYLCYTOSINE; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CYTOSINE; DNA METHYLATION; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; DUAL-SPECIFICITY PHOSPHATASES; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLIOBLASTOMA; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; ISOCITRATE DEHYDROGENASE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; MUTATION; PROTO-ONCOGENE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SUBCELLULAR FRACTIONS; TUMOR SUPPRESSOR PROTEINS;

EID: 84864120277     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.04.017     Document Type: Article

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