-
1
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird, A. (2002) DNA methylation patterns and epigenetic memory. Genes Dev., 16, 6-21.
-
(2002)
Genes Dev.
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
2
-
-
82955207588
-
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
-
Wu, H. and Zhang, Y. (2011) Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev., 25, 2436-2452.
-
(2011)
Genes Dev.
, vol.25
, pp. 2436-2452
-
-
Wu, H.1
Zhang, Y.2
-
3
-
-
84865843074
-
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline
-
Hackett, J.A., Reddington, J.P., Nestor, C.E., Dunican, D.S., Branco, M.R., Reichmann, J., Reik, W., Surani, M.A., Adams, I.R. and Meehan, R.R. (2012) Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development, 139, 3623-3632.
-
(2012)
Development
, vol.139
, pp. 3623-3632
-
-
Hackett, J.A.1
Reddington, J.P.2
Nestor, C.E.3
Dunican, D.S.4
Branco, M.R.5
Reichmann, J.6
Reik, W.7
Surani, M.A.8
Adams, I.R.9
Meehan, R.R.10
-
4
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu, H., D'Alessio, A.C., Ito, S., Wang, Z., Cui, K., Zhao, K., Sun, Y.E. and Zhang, Y. (2011) Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev., 25, 679-684.
-
(2011)
Genes Dev.
, vol.25
, pp. 679-684
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Wang, Z.4
Cui, K.5
Zhao, K.6
Sun, Y.E.7
Zhang, Y.8
-
5
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu, H., D'Alessio, A.C., Ito, S., Xia, K., Wang, Z., Cui, K., Zhao, K., Eve Sun, Y. and Zhang, Y. (2011) Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature, 473, 389-393.
-
(2011)
Nature
, vol.473
, pp. 389-393
-
-
Wu, H.1
D'Alessio, A.C.2
Ito, S.3
Xia, K.4
Wang, Z.5
Cui, K.6
Zhao, K.7
Eve Sun, Y.8
Zhang, Y.9
-
6
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor, W.A., Pape, U.J., Huang, Y., Henderson, H.R., Lister, R., Ko, M., McLoughlin, E.M., Brudno, Y., Mahapatra, S., Kapranov, P. et al. (2011) Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature, 473, 394-397.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
Ko, M.6
McLoughlin, E.M.7
Brudno, Y.8
Mahapatra, S.9
Kapranov, P.10
-
7
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams, K., Christensen, J., Pedersen, M.T., Johansen, J.V., Cloos, P.A., Rappsilber, J. and Helin, K. (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature, 473, 343-348.
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
Johansen, J.V.4
Cloos, P.A.5
Rappsilber, J.6
Helin, K.7
-
8
-
-
79959209733
-
5-hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
-
Stroud, H., Feng, S., Morey Kinney, S., Pradhan, S. and Jacobsen, S.E. (2011) 5-hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biol., 12, R54.
-
(2011)
Genome Biol.
, vol.12
-
-
Stroud, H.1
Feng, S.2
Morey Kinney, S.3
Pradhan, S.4
Jacobsen, S.E.5
-
9
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by tet1 hydroxylase in mouse embryonic stem cells
-
Xu, Y., Wu, F., Tan, L., Kong, L., Xiong, L., Deng, J., Barbera, A.J., Zheng, L., Zhang, H., Huang, S. et al. (2011) Genome-wide regulation of 5hmC, 5mC, and gene expression by tet1 hydroxylase in mouse embryonic stem cells. Mol. Cell, 42, 451-464.
-
(2011)
Mol. Cell
, vol.42
, pp. 451-464
-
-
Xu, Y.1
Wu, F.2
Tan, L.3
Kong, L.4
Xiong, L.5
Deng, J.6
Barbera, A.J.7
Zheng, L.8
Zhang, H.9
Huang, S.10
-
10
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu, M., Hon, G.C., Szulwach, K.E., Song, C.X., Zhang, L., Kim, A., Li, X., Dai, Q., Shen, Y., Park, B. et al. (2012) Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell, 149, 1368-1380.
-
(2012)
Cell
, vol.149
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
Song, C.X.4
Zhang, L.5
Kim, A.6
Li, X.7
Dai, Q.8
Shen, Y.9
Park, B.10
-
11
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz, G., Branco, M.R., Seisenberger, S., Santos, F., Krueger, F., Hore, T.A., Marques, C.J., Andrews, S. and Reik, W. (2011) Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature, 473, 398-402.
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
Branco, M.R.2
Seisenberger, S.3
Santos, F.4
Krueger, F.5
Hore, T.A.6
Marques, C.J.7
Andrews, S.8
Reik, W.9
-
12
-
-
84866936331
-
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers
-
Serandour, A.A., Avner, S., Oger, F., Bizot, M., Percevault, F., Lucchetti-Miganeh, C., Palierne, G., Gheeraert, C., Barloy-Hubler, F., Peron, C.L. et al. (2012) Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers. Nucleic Acids Res., 40, 8255-8265.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 8255-8265
-
-
Serandour, A.A.1
Avner, S.2
Oger, F.3
Bizot, M.4
Percevault, F.5
Lucchetti-Miganeh, C.6
Palierne, G.7
Gheeraert, C.8
Barloy-Hubler, F.9
Peron, C.L.10
-
13
-
-
84864311315
-
Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster
-
Bocker, M.T., Tuorto, F., Raddatz, G., Musch, T., Yang, F.C., Xu, M., Lyko, F. and Breiling, A. (2012) Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster. Nat. Commun., 3, 818.
-
(2012)
Nat. Commun.
, vol.3
, pp. 818
-
-
Bocker, M.T.1
Tuorto, F.2
Raddatz, G.3
Musch, T.4
Yang, F.C.5
Xu, M.6
Lyko, F.7
Breiling, A.8
-
14
-
-
84861221693
-
Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution
-
Booth, M.J., Branco, M.R., Ficz, G., Oxley, D., Krueger, F., Reik, W. and Balasubramanian, S. (2012) Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science, 336, 934-937.
-
(2012)
Science
, vol.336
, pp. 934-937
-
-
Booth, M.J.1
Branco, M.R.2
Ficz, G.3
Oxley, D.4
Krueger, F.5
Reik, W.6
Balasubramanian, S.7
-
15
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M., Koh, K.P., Shen, Y., Pastor, W.A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L.M., Liu, D.R., Aravind, L. et al. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science, 324, 930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
-
16
-
-
84857891830
-
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
-
Nestor, C.E., Ottaviano, R., Reddington, J., Sproul, D., Reinhardt, D., Dunican, D., Katz, E., Dixon, J.M., Harrison, D.J. and Meehan, R.R. (2012) Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Res., 22, 467-477.
-
(2012)
Genome Res.
, vol.22
, pp. 467-477
-
-
Nestor, C.E.1
Ottaviano, R.2
Reddington, J.3
Sproul, D.4
Reinhardt, D.5
Dunican, D.6
Katz, E.7
Dixon, J.M.8
Harrison, D.J.9
Meehan, R.R.10
-
17
-
-
84866847877
-
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome
-
Thomson, J.P., Lempiainen, H., Hackett, J.A., Nestor, C.E., Muller, A., Bolognani, F., Oakeley, E.J., Schubeler, D., Terranova, R., Reinhardt, D. et al. (2012) Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome. Genome Biol., 13, R93.
-
(2012)
Genome Biol.
, vol.13
-
-
Thomson, J.P.1
Lempiainen, H.2
Hackett, J.A.3
Nestor, C.E.4
Muller, A.5
Bolognani, F.6
Oakeley, E.J.7
Schubeler, D.8
Terranova, R.9
Et Al., R.D.10
-
18
-
-
78651280460
-
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
-
Song, C.X., Szulwach, K.E., Fu, Y., Dai, Q., Yi, C., Li, X., Li, Y., Chen, C.H., Zhang, W., Jian, X. et al. (2011) Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat. Biotechnol., 29, 68-72.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 68-72
-
-
Song, C.X.1
Szulwach, K.E.2
Fu, Y.3
Dai, Q.4
Yi, C.5
Li, X.6
Li, Y.7
Chen, C.H.8
Zhang, W.9
Jian, X.10
-
19
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko, M., Huang, Y., Jankowska, A.M., Pape, U.J., Tahiliani, M., Bandukwala, H.S., An, J., Lamperti, E.D., Koh, K.P., Ganetzky, R. et al. (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature, 468, 839-843.
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
An, J.7
Lamperti, E.D.8
Koh, K.P.9
Ganetzky, R.10
-
20
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh, K.P., Yabuuchi, A., Rao, S., Huang, Y., Cunniff, K., Nardone, J., Laiho, A., Tahiliani, M., Sommer, C.A., Mostoslavsky, G. et al. (2011) Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell, 8, 200-213.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 200-213
-
-
Koh, K.P.1
Yabuuchi, A.2
Rao, S.3
Huang, Y.4
Cunniff, K.5
Nardone, J.6
Laiho, A.7
Tahiliani, M.8
Sommer, C.A.9
Mostoslavsky, G.10
-
21
-
-
79952713567
-
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
Wossidlo, M., Nakamura, T., Lepikhov, K., Marques, C.J., Zakhartchenko, V., Boiani, M., Arand, J., Nakano, T., Reik, W. and Walter, J. (2011) 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat. Commun., 2, 241.
-
(2011)
Nat. Commun.
, vol.2
, pp. 241
-
-
Wossidlo, M.1
Nakamura, T.2
Lepikhov, K.3
Marques, C.J.4
Zakhartchenko, V.5
Boiani, M.6
Arand, J.7
Nakano, T.8
Reik, W.9
Walter, J.10
-
22
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito, S., D'Alessio, A.C., Taranova, O.V., Hong, K., Sowers, L.C. and Zhang, Y. (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature, 466, 1129-1133.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
23
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito, S., Shen, L., Dai, Q., Wu, S.C., Collins, L.B., Swenberg, J.A., He, C. and Zhang, Y. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science, 333, 1300-1303.
-
(2011)
Science
, vol.333
, pp. 1300-1303
-
-
Ito, S.1
Shen, L.2
Dai, Q.3
Wu, S.C.4
Collins, L.B.5
Swenberg, J.A.6
He, C.7
Zhang, Y.8
-
24
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D. et al. (2011) Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell, 146, 67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
-
25
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He, Y.F., Li, B.Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, L. et al. (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science, 333, 1303-1307.
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
-
26
-
-
82655187105
-
Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development
-
Inoue, A., Shen, L., Dai, Q., He, C. and Zhang, Y. (2011) Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Res., 21, 1670-1676.
-
(2011)
Cell Res.
, vol.21
, pp. 1670-1676
-
-
Inoue, A.1
Shen, L.2
Dai, Q.3
He, C.4
Zhang, Y.5
-
27
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue, A. and Zhang, Y. (2011) Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science, 334, 194.
-
(2011)
Science
, vol.334
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
28
-
-
84872770694
-
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine
-
Hackett, J.A., Sengupta, R., Zylicz, J.J., Murakami, K., Lee, C., Down, T.A. and Surani, M.A. (2012) Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine. Science, 339, 448-452.
-
(2012)
Science
, vol.339
, pp. 448-452
-
-
Hackett, J.A.1
Sengupta, R.2
Zylicz, J.J.3
Murakami, K.4
Lee, C.5
Down, T.A.6
Surani, M.A.7
-
29
-
-
84871702441
-
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
-
Seisenberger, S., Andrews, S., Krueger, F., Arand, J., Walter, J., Santos, F., Popp, C., Thienpont, B., Dean, W. and Reik, W. (2012) The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol. Cell, 48, 849-862.
-
(2012)
Mol. Cell
, vol.48
, pp. 849-862
-
-
Seisenberger, S.1
Andrews, S.2
Krueger, F.3
Arand, J.4
Walter, J.5
Santos, F.6
Popp, C.7
Thienpont, B.8
Dean, W.9
Reik, W.10
-
30
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
Lian, C.G., Xu, Y., Ceol, C., Wu, F., Larson, A., Dresser, K., Xu, W., Tan, L., Hu, Y., Zhan, Q. et al. (2012) Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell, 150, 1135-1146.
-
(2012)
Cell
, vol.150
, pp. 1135-1146
-
-
Lian, C.G.1
Xu, Y.2
Ceol, C.3
Wu, F.4
Larson, A.5
Dresser, K.6
Xu, W.7
Tan, L.8
Hu, Y.9
Zhan, Q.10
-
31
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio, K., Reavie, L., Shih, A., Abdel-Wahab, O., Ndiaye-Lobry, D., Lobry, C., Figueroa, M.E., Vasanthakumar, A., Patel, J., Zhao, X. et al. (2011) Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell, 20, 11-24.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
Figueroa, M.E.7
Vasanthakumar, A.8
Patel, J.9
Zhao, X.10
-
32
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa, M.E., Abdel-Wahab, O., Lu, C., Ward, P.S., Patel, J., Shih, A., Li, Y., Bhagwat, N., Vasanthakumar, A., Fernandez, H.F. et al. (2010) Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell, 18, 553-567.
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
Shih, A.6
Li, Y.7
Bhagwat, N.8
Vasanthakumar, A.9
Fernandez, H.F.10
-
33
-
-
84868103289
-
Tet2 facilitates the derepression of myeloid target genes during cebpalpha-induced transdifferentiation of pre-B cells
-
Kallin, E.M., Rodriguez-Ubreva, J., Christensen, J., Cimmino, L., Aifantis, I., Helin, K., Ballestar, E. and Graf, T. (2012) Tet2 facilitates the derepression of myeloid target genes during cebpalpha-induced transdifferentiation of pre-B cells. Mol. Cell, 48, 266-276.
-
(2012)
Mol. Cell
, vol.48
, pp. 266-276
-
-
Kallin, E.M.1
Rodriguez-Ubreva, J.2
Christensen, J.3
Cimmino, L.4
Aifantis, I.5
Helin, K.6
Ballestar, E.7
Graf, T.8
-
34
-
-
79953035873
-
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice
-
Lempiainen, H., Muller, A., Brasa, S., Teo, S.S., Roloff, T.C., Morawiec, L., Zamurovic, N., Vicart, A., Funhoff, E., Couttet, P. et al. (2011) Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice. PLoS One, 6, e18216.
-
(2011)
PLoS One
, vol.6
-
-
Lempiainen, H.1
Muller, A.2
Brasa, S.3
Teo, S.S.4
Roloff, T.C.5
Morawiec, L.6
Zamurovic, N.7
Vicart, A.8
Funhoff, E.9
Couttet, P.10
-
35
-
-
33847331654
-
Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis
-
Phillips, J.M., Yamamoto, Y., Negishi, M., Maronpot, R.R. and Goodman, J.I. (2007) Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis. Toxicol. Sci., 96, 72-82.
-
(2007)
Toxicol. Sci.
, vol.96
, pp. 72-82
-
-
Phillips, J.M.1
Yamamoto, Y.2
Negishi, M.3
Maronpot, R.R.4
Goodman, J.I.5
-
36
-
-
0036094163
-
Epigenetics and DNA methylation come of age in toxicology
-
Watson, R.E. and Goodman, J.I. (2002) Epigenetics and DNA methylation come of age in toxicology. Toxicol. Sci., 67, 11-16.
-
(2002)
Toxicol. Sci.
, vol.67
, pp. 11-16
-
-
Watson, R.E.1
Goodman, J.I.2
-
37
-
-
84866847877
-
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome
-
Thomson, J.P., Lempiainen, H., Hackett, J., Nestor, C., Muller, A., Bolognani, F., Oakeley, E.J., Schubeler, D., Terranova, R., Reinhardt, D. et al. (2012) Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome. Genome Biol., 13, R93.
-
(2012)
Genome Biol.
, vol.13
-
-
Thomson, J.P.1
Lempiainen, H.2
Hackett, J.3
Nestor, C.4
Muller, A.5
Bolognani, F.6
Oakeley, E.J.7
Schubeler, D.8
Terranova, R.9
Reinhardt, D.10
-
38
-
-
0037108681
-
Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital
-
Loeppen, S., Schneider, D., Gaunitz, F., Gebhardt, R., Kurek, R., Buchmann, A. and Schwarz, M. (2002) Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital. Cancer Res., 62, 5685-5688.
-
(2002)
Cancer Res.
, vol.62
, pp. 5685-5688
-
-
Loeppen, S.1
Schneider, D.2
Gaunitz, F.3
Gebhardt, R.4
Kurek, R.5
Buchmann, A.6
Schwarz, M.7
-
39
-
-
15644384598
-
AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line
-
Rencurel, F., Stenhouse, A., Hawley, S.A., Friedberg, T., Hardie, D.G., Sutherland, C. and Wolf, C.R. (2005) AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line. J. Biol. Chem., 280, 4367-4373.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4367-4373
-
-
Rencurel, F.1
Stenhouse, A.2
Hawley, S.A.3
Friedberg, T.4
Hardie, D.G.5
Sutherland, C.6
Wolf, C.R.7
-
40
-
-
79957912993
-
EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis
-
Cheng, A.S., Lau, S.S., Chen, Y., Kondo, Y., Li, M.S., Feng, H., Ching, A.K., Cheung, K.F., Wong, H.K., Tong, J.H. et al. (2011) EZH2-mediated concordant repression of Wnt antagonists promotes beta-catenin-dependent hepatocarcinogenesis. Cancer Res., 71, 4028-4039.
-
(2011)
Cancer Res.
, vol.71
, pp. 4028-4039
-
-
Cheng, A.S.1
Lau, S.S.2
Chen, Y.3
Kondo, Y.4
Li, M.S.5
Feng, H.6
Ching, A.K.7
Cheung, K.F.8
Wong, H.K.9
Tong, J.H.10
-
41
-
-
80052245751
-
DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival
-
Luk, J.M., Burchard, J., Zhang, C., Liu, A.M., Wong, K.F., Shek, F.H., Lee, N.P., Fan, S.T., Poon, R.T., Ivanovska, I. et al. (2011) DLK1-DIO3 genomic imprinted microRNA cluster at 14q32.2 defines a stemlike subtype of hepatocellular carcinoma associated with poor survival. J. Biol. Chem., 286, 30706-30713.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30706-30713
-
-
Luk, J.M.1
Burchard, J.2
Zhang, C.3
Liu, A.M.4
Wong, K.F.5
Shek, F.H.6
Lee, N.P.7
Fan, S.T.8
Poon, R.T.9
Ivanovska, I.10
-
42
-
-
83255194128
-
CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells
-
Monnier, J., Boissan, M., L'Helgoualc'h, A., Lacombe, M.L., Turlin, B., Zucman-Rossi, J., Theret, N., Piquet-Pellorce, C. and Samson, M. (2012) CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells. Eur. J. Cancer, 48, 138-148.
-
(2012)
Eur. J. Cancer
, vol.48
, pp. 138-148
-
-
Monnier, J.1
Boissan, M.2
L'Helgoualc'H, A.3
Lacombe, M.L.4
Turlin, B.5
Zucman-Rossi, J.6
Theret, N.7
Piquet-Pellorce, C.8
Samson, M.9
-
43
-
-
4544341015
-
Linear models and empirical bayes methods for assessing differential expression in microarray experiments
-
Article3
-
Smyth, G.K. (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Mol. Biol., 3, Article3.
-
(2004)
Stat. Appl. Genet. Mol. Biol.
, pp. 3
-
-
Smyth, G.K.1
-
44
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
Bolstad, B.M., Irizarry, R.A., Astrand, M. and Speed, T.P. (2003) A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics, 19, 185-193.
-
(2003)
Bioinformatics
, vol.19
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
45
-
-
84864462544
-
A map of the cis-regulatory sequences in the mouse genome
-
Shen, Y., Yue, F., McCleary, D.F., Ye, Z., Edsall, L., Kuan, S., Wagner, U., Dixon, J., Lee, L., Lobanenkov, V.V. et al. (2012) A map of the cis-regulatory sequences in the mouse genome. Nature, 488, 116-120.
-
(2012)
Nature
, vol.488
, pp. 116-120
-
-
Shen, Y.1
Yue, F.2
McCleary, D.F.3
Ye, Z.4
Edsall, L.5
Kuan, S.6
Wagner, U.7
Dixon, J.8
Lee, L.9
Lobanenkov, V.V.10
-
46
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber, M., Hellmann, I., Stadler, M.B., Ramos, L., Paabo, S., Rebhan, M. and Schubeler, D. (2007) Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat. Genet., 39, 457-466.
-
(2007)
Nat. Genet.
, vol.39
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
47
-
-
84869397620
-
MeDIP-HMM: Genome-wide identification of distinct DNA methylation states from high-density tiling arrays
-
Seifert, M., Cortijo, S., Colome-Tatche, M., Johannes, F., Roudier, F. and Colot, V. (2012) MeDIP-HMM: genome-wide identification of distinct DNA methylation states from high-density tiling arrays. Bioinformatics, 28, 2930-2939.
-
(2012)
Bioinformatics
, vol.28
, pp. 2930-2939
-
-
Seifert, M.1
Cortijo, S.2
Colome-Tatche, M.3
Johannes, F.4
Roudier, F.5
Colot, V.6
-
48
-
-
46949098742
-
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis
-
Down, T.A., Rakyan, V.K., Turner, D.J., Flicek, P., Li, H., Kulesha, E., Graf, S., Johnson, N., Herrero, J., Tomazou, E.M. et al. (2008) A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis. Nat. Biotechnol., 26, 779-785.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 779-785
-
-
Down, T.A.1
Rakyan, V.K.2
Turner, D.J.3
Flicek, P.4
Li, H.5
Kulesha, E.6
Graf, S.7
Johnson, N.8
Herrero, J.9
Tomazou, E.M.10
-
49
-
-
78651251739
-
Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias
-
Nair, S.S., Coolen, M.W., Stirzaker, C., Song, J.Z., Statham, A.L., Strbenac, D., Robinson, M.D. and Clark, S.J. (2011) Comparison of methyl-DNA immunoprecipitation (MeDIP) and methyl-CpG binding domain (MBD) protein capture for genome-wide DNA methylation analysis reveal CpG sequence coverage bias. Epigenetics, 6, 34-44.
-
(2011)
Epigenetics
, vol.6
, pp. 34-44
-
-
Nair, S.S.1
Coolen, M.W.2
Stirzaker, C.3
Song, J.Z.4
Statham, A.L.5
Strbenac, D.6
Robinson, M.D.7
Clark, S.J.8
-
50
-
-
0033924973
-
Histometrical and threedimensional analyses of liver hematopoiesis in the mouse embryo
-
Sasaki, K. and Sonoda, Y. (2000) Histometrical and threedimensional analyses of liver hematopoiesis in the mouse embryo. Arch. Histol. Cytol., 63, 137-146.
-
(2000)
Arch. Histol. Cytol.
, vol.63
, pp. 137-146
-
-
Sasaki, K.1
Sonoda, Y.2
-
51
-
-
34447532441
-
Beta-Catenin is critical for early postnatal liver growth
-
Apte, U., Zeng, G., Thompson, M.D., Muller, P., Micsenyi, A., Cieply, B., Kaestner, K.H. and Monga, S.P. (2007) beta-Catenin is critical for early postnatal liver growth. Am. J. Physiol. Gastrointest. Liver Physiol., 292, G1578-G1585.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.292
-
-
Apte, U.1
Zeng, G.2
Thompson, M.D.3
Muller, P.4
Micsenyi, A.5
Cieply, B.6
Kaestner, K.H.7
Monga, S.P.8
-
52
-
-
34249729341
-
Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns
-
Otu, H.H., Naxerova, K., Ho, K., Can, H., Nesbitt, N., Libermann, T.A. and Karp, S.J. (2007) Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns. J. Biol. Chem., 282, 11197-11204.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11197-11204
-
-
Otu, H.H.1
Naxerova, K.2
Ho, K.3
Can, H.4
Nesbitt, N.5
Libermann, T.A.6
Karp, S.J.7
-
53
-
-
84873844990
-
Identification of Dlk1-Dio3 imprinted gene cluster non-coding RNAs as novel candidate biomarkers for liver tumor promotion
-
Lempiainen, H., Couttet, P., Bolognani, F., Muller, A., Dubost, V., Luisier, R., Del Rio Espinola, A., Vitry, V., Unterberger, E., Thomson, J.P. et al. (2013) Identification of Dlk1-Dio3 imprinted gene cluster non-coding RNAs as novel candidate biomarkers for liver tumor promotion. Toxicol. Sci., 131, 375-386.
-
(2013)
Toxicol. Sci.
, vol.131
, pp. 375-386
-
-
Lempiainen, H.1
Couttet, P.2
Bolognani, F.3
Muller, A.4
Dubost, V.5
Luisier, R.6
Del Rio Espinola, A.7
Vitry, V.8
Unterberger, E.9
Thomson, J.P.10
-
54
-
-
0035936026
-
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors
-
Aydinlik, H., Nguyen, T.D., Moennikes, O., Buchmann, A. and Schwarz, M. (2001) Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. Oncogene, 20, 7812-7816.
-
(2001)
Oncogene
, vol.20
, pp. 7812-7816
-
-
Aydinlik, H.1
Nguyen, T.D.2
Moennikes, O.3
Buchmann, A.4
Schwarz, M.5
-
55
-
-
77749277177
-
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing
-
Huang, Y., Pastor, W.A., Shen, Y., Tahiliani, M., Liu, D.R. and Rao, A. (2010) The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. PLoS One, 5, e8888.
-
(2010)
PLoS One
, vol.5
-
-
Huang, Y.1
Pastor, W.A.2
Shen, Y.3
Tahiliani, M.4
Liu, D.R.5
Rao, A.6
-
56
-
-
84869392308
-
Mapping recently identified nucleotide variants in the genome and transcriptome
-
Song, C.X., Yi, C. and He, C. (2012) Mapping recently identified nucleotide variants in the genome and transcriptome. Nat. Biotechnol., 30, 1107-1116.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 1107-1116
-
-
Song, C.X.1
Yi, C.2
He, C.3
-
57
-
-
79960249232
-
Genomic mapping of 5-hydroxymethylcytosine in the human brain
-
Jin, S.G., Wu, X., Li, A.X. and Pfeifer, G.P. (2011) Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res., 39, 5015-5024.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5015-5024
-
-
Jin, S.G.1
Wu, X.2
Li, A.X.3
Pfeifer, G.P.4
-
58
-
-
84857891830
-
Tissue-type is a major modifier of the 5-hydroxymethylcytosine content of human genes
-
Nestor, C., Ottaviano, R., Reinhardt, D., Sproul, D., Dunican, D.S., Reddingtion, J.P., Katz, E., Dixon, M., Harrison, D.J. and Meehan, R. (2011) Tissue-type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Res., 22, 467-477.
-
(2011)
Genome Res.
, vol.22
, pp. 467-477
-
-
Nestor, C.1
Ottaviano, R.2
Reinhardt, D.3
Sproul, D.4
Dunican, D.S.5
Reddingtion, J.P.6
Katz, E.7
Dixon, M.8
Harrison, D.J.9
Meehan, R.10
-
59
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis, S. and Heintz, N. (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 324, 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
60
-
-
77953532417
-
Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells
-
Liu, L., Luo, G.Z., Yang, W., Zhao, X., Zheng, Q., Lv, Z., Li, W., Wu, H.J., Wang, L., Wang, X.J. et al. (2010) Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J. Biol. Chem., 285, 19483-19490.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19483-19490
-
-
Liu, L.1
Luo, G.Z.2
Yang, W.3
Zhao, X.4
Zheng, Q.5
Lv, Z.6
Li, W.7
Wu, H.J.8
Wang, L.9
Wang, X.J.10
-
61
-
-
77952425747
-
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
-
Stadtfeld, M., Apostolou, E., Akutsu, H., Fukuda, A., Follett, P., Natesan, S., Kono, T., Shioda, T. and Hochedlinger, K. (2010) Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature, 465, 175-181.
-
(2010)
Nature
, vol.465
, pp. 175-181
-
-
Stadtfeld, M.1
Apostolou, E.2
Akutsu, H.3
Fukuda, A.4
Follett, P.5
Natesan, S.6
Kono, T.7
Shioda, T.8
Hochedlinger, K.9
-
62
-
-
67650735625
-
The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors
-
Phillips, J.M., Burgoon, L.D. and Goodman, J.I. (2009) The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors. Toxicol. Sci., 110, 319-333.
-
(2009)
Toxicol. Sci.
, vol.110
, pp. 319-333
-
-
Phillips, J.M.1
Burgoon, L.D.2
Goodman, J.I.3
-
63
-
-
66149107971
-
Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice
-
Phillips, J.M., Burgoon, L.D. and Goodman, J.I. (2009) Phenobarbital elicits unique, early changes in the expression of hepatic genes that affect critical pathways in tumor-prone B6C3F1 mice. Toxicol. Sci., 109, 193-205.
-
(2009)
Toxicol. Sci.
, vol.109
, pp. 193-205
-
-
Phillips, J.M.1
Burgoon, L.D.2
Goodman, J.I.3
-
64
-
-
3042697182
-
Activation of beta-catenin provides proliferative and invasive advantages in c-myc/TGF-alpha hepatocarcinogenesis promoted by phenobarbital
-
Calvisi, D.F., Ladu, S., Factor, V.M. and Thorgeirsson, S.S. (2004) Activation of beta-catenin provides proliferative and invasive advantages in c-myc/TGF-alpha hepatocarcinogenesis promoted by phenobarbital. Carcinogenesis, 25, 901-908.
-
(2004)
Carcinogenesis
, vol.25
, pp. 901-908
-
-
Calvisi, D.F.1
Ladu, S.2
Factor, V.M.3
Thorgeirsson, S.S.4
-
65
-
-
33845705732
-
Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma
-
Chua, M.S., Sun, H., Cheung, S.T., Mason, V., Higgins, J., Ross, D.T., Fan, S.T. and So, S. (2007) Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma. Mod. Pathol., 20, 76-83.
-
(2007)
Mod. Pathol.
, vol.20
, pp. 76-83
-
-
Chua, M.S.1
Sun, H.2
Cheung, S.T.3
Mason, V.4
Higgins, J.5
Ross, D.T.6
Fan, S.T.7
So, S.8
-
66
-
-
5644295430
-
The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice
-
Yamamoto, Y., Moore, R., Goldsworthy, T.L., Negishi, M. and Maronpot, R.R. (2004) The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice. Cancer Res., 64, 7197-7200.
-
(2004)
Cancer Res.
, vol.64
, pp. 7197-7200
-
-
Yamamoto, Y.1
Moore, R.2
Goldsworthy, T.L.3
Negishi, M.4
Maronpot, R.R.5
-
67
-
-
29544450979
-
Mode of action in relevance of rodent liver tumors to human cancer risk
-
Holsapple, M.P., Pitot, H.C., Cohen, S.M., Boobis, A.R., Klaunig, J.E., Pastoor, T., Dellarco, V.L. and Dragan, Y.P. (2006) Mode of action in relevance of rodent liver tumors to human cancer risk. Toxicol. Sci., 89, 51-56.
-
(2006)
Toxicol. Sci.
, vol.89
, pp. 51-56
-
-
Holsapple, M.P.1
Pitot, H.C.2
Cohen, S.M.3
Boobis, A.R.4
Klaunig, J.E.5
Pastoor, T.6
Dellarco, V.L.7
Dragan, Y.P.8
-
68
-
-
0031682988
-
The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
-
Honkakoski, P., Zelko, I., Sueyoshi, T. and Negishi, M. (1998) The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol. Cell. Biol., 18, 5652-5658.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5652-5658
-
-
Honkakoski, P.1
Zelko, I.2
Sueyoshi, T.3
Negishi, M.4
-
69
-
-
0033652116
-
Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene
-
Kawamoto, T., Kakizaki, S., Yoshinari, K. and Negishi, M. (2000) Estrogen activation of the nuclear orphan receptor CAR (constitutive active receptor) in induction of the mouse Cyp2b10 gene. Mol. Endocrinol., 14, 1897-1905.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1897-1905
-
-
Kawamoto, T.1
Kakizaki, S.2
Yoshinari, K.3
Negishi, M.4
-
70
-
-
77953737472
-
The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver
-
Konno, Y., Kamino, H., Moore, R., Lih, F., Tomer, K.B., Zeldin, D.C., Goldstein, J.A. and Negishi, M. (2010) The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver. Drug Metab. Dispos., 38, 1177-1182.
-
(2010)
Drug Metab. Dispos.
, vol.38
, pp. 1177-1182
-
-
Konno, Y.1
Kamino, H.2
Moore, R.3
Lih, F.4
Tomer, K.B.5
Zeldin, D.C.6
Goldstein, J.A.7
Negishi, M.8
-
71
-
-
38949094492
-
Cytochrome p450 and chemical toxicology
-
Guengerich, F.P. (2008) Cytochrome p450 and chemical toxicology. Chem. Res. Toxicol., 21, 70-83.
-
(2008)
Chem. Res. Toxicol.
, vol.21
, pp. 70-83
-
-
Guengerich, F.P.1
-
72
-
-
12844268268
-
Glutathione transferases
-
Hayes, J.D., Flanagan, J.U. and Jowsey, I.R. (2005) Glutathione transferases. Annu. Rev. Pharmacol. Toxicol., 45, 51-88.
-
(2005)
Annu. Rev. Pharmacol. Toxicol.
, vol.45
, pp. 51-88
-
-
Hayes, J.D.1
Flanagan, J.U.2
Jowsey, I.R.3
-
73
-
-
0037252660
-
Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation
-
Xie, H.J., Yasar, U., Lundgren, S., Griskevicius, L., Terelius, Y., Hassan, M. and Rane, A. (2003) Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation. Pharmacogenomics J., 3, 53-61.
-
(2003)
Pharmacogenomics J.
, vol.3
, pp. 53-61
-
-
Xie, H.J.1
Yasar, U.2
Lundgren, S.3
Griskevicius, L.4
Terelius, Y.5
Hassan, M.6
Rane, A.7
-
74
-
-
84858069933
-
Monitoring Cyp2b10 mRNA expression at cessation of 2-year carcinogenesis bioassay in mouse liver provides evidence for a carcinogenic mechanism devoid of human relevance: The dalcetrapib experience
-
Hoflack, J.C., Mueller, L., Fowler, S., Braendli-Baiocco, A., Flint, N., Kuhlmann, O., Singer, T. and Roth, A. (2012) Monitoring Cyp2b10 mRNA expression at cessation of 2-year carcinogenesis bioassay in mouse liver provides evidence for a carcinogenic mechanism devoid of human relevance: the dalcetrapib experience. Toxicol. Appl. Pharmacol., 259, 355-365.
-
(2012)
Toxicol. Appl. Pharmacol.
, vol.259
, pp. 355-365
-
-
Hoflack, J.C.1
Mueller, L.2
Fowler, S.3
Braendli-Baiocco, A.4
Flint, N.5
Kuhlmann, O.6
Singer, T.7
Roth, A.8
-
75
-
-
79959789151
-
Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice
-
Lahousse, S.A., Hoenerhoff, M., Collins, J., Ton, T.V., Masinde, T., Olson, D., Rebolloso, Y., Koujitani, T., Tomer, K.B., Hong, H.H. et al. (2011) Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice. Vet. Pathol., 48, 875-884.
-
(2011)
Vet. Pathol.
, vol.48
, pp. 875-884
-
-
Lahousse, S.A.1
Hoenerhoff, M.2
Collins, J.3
Ton, T.V.4
Masinde, T.5
Olson, D.6
Rebolloso, Y.7
Koujitani, T.8
Tomer, K.B.9
Hong, H.H.10
-
76
-
-
84869052714
-
Loss of imprinting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma
-
Anwar, S.L., Krech, T., Hasemeier, B., Schipper, E., Schweitzer, N., Vogel, A., Kreipe, H. and Lehmann, U. (2012) Loss of imprinting and allelic switching at the DLK1-MEG3 locus in human hepatocellular carcinoma. PLoS One, 7, e49462.
-
(2012)
PLoS One
, vol.7
-
-
Anwar, S.L.1
Krech, T.2
Hasemeier, B.3
Schipper, E.4
Schweitzer, N.5
Vogel, A.6
Kreipe, H.7
Lehmann, U.8
-
77
-
-
33846581497
-
Loss of imprinting and cancer
-
Jelinic, P. and Shaw, P. (2007) Loss of imprinting and cancer. J. Pathol., 211, 261-268.
-
(2007)
J. Pathol.
, vol.211
, pp. 261-268
-
-
Jelinic, P.1
Shaw, P.2
-
78
-
-
70449366626
-
Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells
-
Wei, W., Chua, M.S., Grepper, S. and So, S.K. (2009) Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells. Mol. Cancer, 8, 76.
-
(2009)
Mol. Cancer
, vol.8
, pp. 76
-
-
Wei, W.1
Chua, M.S.2
Grepper, S.3
So, S.K.4
-
79
-
-
0034687397
-
The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism
-
Wei, P., Zhang, J., Egan-Hafley, M., Liang, S. and Moore, D.D. (2000) The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. Nature, 407, 920-923.
-
(2000)
Nature
, vol.407
, pp. 920-923
-
-
Wei, P.1
Zhang, J.2
Egan-Hafley, M.3
Liang, S.4
Moore, D.D.5
-
80
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor, W.A., Pape, U.J., Huang, Y., Henderson, H.R., Lister, R., Ko, M., McLoughlin, E.M., Brudno, Y., Mahapatra, S., Kapranov, P. et al. (2011) Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature, 473, 394-397.
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
Pape, U.J.2
Huang, Y.3
Henderson, H.R.4
Lister, R.5
Ko, M.6
McLoughlin, E.M.7
Brudno, Y.8
Mahapatra, S.9
Kapranov, P.10
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