-
1
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
Hansen KD, et al. (2011) Increased methylation variation in epigenetic domains across cancer types. Nat Genet 43(8):768-775.
-
(2011)
Nat Genet
, vol.43
, Issue.8
, pp. 768-775
-
-
Hansen, K.D.1
-
2
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo JU, Su Y, Zhong C, Ming GL, Song H (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145(3):423-434.
-
(2011)
Cell
, vol.145
, Issue.3
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
3
-
-
80052461558
-
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
-
Ito S, et al. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333(6047):1300-1303.
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1300-1303
-
-
Ito, S.1
-
4
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He YF, et al. (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333(6047):1303-1307.
-
(2011)
Science
, vol.333
, Issue.6047
, pp. 1303-1307
-
-
He, Y.F.1
-
5
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, et al. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324(5929):930-935.
-
(2009)
Science
, vol.324
, Issue.5929
, pp. 930-935
-
-
Tahiliani, M.1
-
6
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue A, Zhang Y (2011) Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 334(6053):194.
-
(2011)
Science
, vol.334
, Issue.6053
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
7
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S, et al. (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466(7310):1129-1133.
-
(2010)
Nature
, vol.466
, Issue.7310
, pp. 1129-1133
-
-
Ito, S.1
-
8
-
-
79551587102
-
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
-
Koh KP, et al. (2011) Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell 8(2):200-213.
-
(2011)
Cell Stem Cell
, vol.8
, Issue.2
, pp. 200-213
-
-
Koh, K.P.1
-
9
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu Y, et al. (2011) Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol Cell 42(4):451-464.
-
(2011)
Mol Cell
, vol.42
, Issue.4
, pp. 451-464
-
-
Xu, Y.1
-
10
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K, et al. (2011) TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473(7347):343-348.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 343-348
-
-
Williams, K.1
-
11
-
-
84856058152
-
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers
-
Haffner MC, et al. (2011) Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers. Oncotarget 2(8):627-637.
-
(2011)
Oncotarget
, vol.2
, Issue.8
, pp. 627-637
-
-
Haffner, M.C.1
-
12
-
-
84863393235
-
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation
-
Kudo Y, et al. (2012) Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation. Cancer Sci 103(4):670-676.
-
(2012)
Cancer Sci
, vol.103
, Issue.4
, pp. 670-676
-
-
Kudo, Y.1
-
13
-
-
84873411803
-
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
-
Yang H, et al. (2013) Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene 32(5):663-669.
-
(2013)
Oncogene
, vol.32
, Issue.5
, pp. 663-669
-
-
Yang, H.1
-
14
-
-
84866419591
-
Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma
-
Lian CG, et al. (2012) Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma. Cell 150(6):1135-1146.
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1135-1146
-
-
Lian, C.G.1
-
15
-
-
36448992338
-
Roles of HMGA proteins in cancer
-
DOI 10.1038/nrc2271, PII NRC2271
-
Fusco A, Fedele M (2007) Roles of HMGA proteins in cancer. Nat Rev Cancer 7(12):899-910. (Pubitemid 350165857)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.12
, pp. 899-910
-
-
Fusco, A.1
Fedele, M.2
-
16
-
-
0030751533
-
Expression of HMGI-C, a member of the high mobility group protein family, in a subset of breast cancers: Relationship to histologic grade
-
DOI 10.1002/(SICI)1098-2744(199707)19:3<153::AID
-
Rogalla P, et al. (1997) Expression of HMGI-C, a member of the high mobility group protein family, in a subset of breast cancers: Relationship to histologic grade. Mol Carcinog 19(3):153-156. (Pubitemid 27360132)
-
(1997)
Molecular Carcinogenesis
, vol.19
, Issue.3
, pp. 153-156
-
-
Rogalla, P.1
Drechsler, K.2
Kazmierczak, B.3
Rippe, V.4
Bonk, U.5
Bullerdiek, J.6
-
17
-
-
0348049851
-
An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue
-
DOI 10.1038/sj.bjc.6601391
-
Abe N, et al. (2003) An increased high-mobility group A2 expression level is associated with malignant phenotype in pancreatic exocrine tissue. Br J Cancer 89(11):2104-2109. (Pubitemid 38030910)
-
(2003)
British Journal of Cancer
, vol.89
, Issue.11
, pp. 2104-2109
-
-
Abe, N.1
Watanabe, T.2
Suzuki, Y.3
Matsumoto, N.4
Masaki, T.5
Mori, T.6
Sugiyama, M.7
Chiappetta, G.8
Fusco, A.9
Atomi, Y.10
-
18
-
-
1542720383
-
Expression of Mesenchyme-Specific Gene HMGA2 in Squamous Cell Carcinomas of the Oral Cavity
-
DOI 10.1158/0008-5472.CAN-03-1855
-
Miyazawa J, Mitoro A, Kawashiri S, Chada KK, Imai K (2004) Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res 64(6):2024-2029. (Pubitemid 38339449)
-
(2004)
Cancer Research
, vol.64
, Issue.6
, pp. 2024-2029
-
-
Miyazawa, J.1
Mitoro, A.2
Kawashiri, S.3
Chada, K.K.4
Imai, K.5
-
19
-
-
34447532061
-
HMGA2 overexpression in non-small cell lung cancer
-
DOI 10.1002/mc.20235
-
Meyer B, et al. (2007) HMGA2 overexpression in non-small cell lung cancer. Mol Carcinog 46(7):503-511. (Pubitemid 47068069)
-
(2007)
Molecular Carcinogenesis
, vol.46
, Issue.7
, pp. 503-511
-
-
Meyer, B.1
Loeschke, S.2
Schultze, A.3
Weigel, T.4
Sandkamp, M.5
Goldmann, T.6
Vollmer, E.7
Bullerdiek, J.8
-
20
-
-
0028041539
-
Mini-mouse: Phenotypic characterization of a transgenic insertional mutant allelic to pygmy
-
Benson KF, Chada K (1994) Mini-mouse: phenotypic characterization of a transgenic insertional mutant allelic to pygmy. Genet Res 64(1):27-33. (Pubitemid 24289475)
-
(1994)
Genetical Research
, vol.64
, Issue.1
, pp. 27-33
-
-
Benson, K.F.1
Chada, K.2
-
21
-
-
80455174648
-
Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer
-
Yun J, et al. (2011) Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J 30(21):4500-4514.
-
(2011)
EMBO J
, vol.30
, Issue.21
, pp. 4500-4514
-
-
Yun, J.1
-
22
-
-
60549104367
-
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
-
Dangi-Garimella S, et al. (2009) Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 28(4):347-358.
-
(2009)
EMBO J
, vol.28
, Issue.4
, pp. 347-358
-
-
Dangi-Garimella, S.1
-
23
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
DOI 10.1016/S1535-6108(03)00132-6
-
Kang Y, et al. (2003) A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 3(6):537-549. (Pubitemid 36808649)
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordon-Cardo, C.6
Guise, T.A.7
Massague, J.8
-
24
-
-
77951605788
-
The Hox genes and their roles in oncogenesis
-
Shah N, Sukumar S (2010) The Hox genes and their roles in oncogenesis. Nat Rev Cancer 10(5):361-371.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.5
, pp. 361-371
-
-
Shah, N.1
Sukumar, S.2
-
25
-
-
79952049614
-
miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors
-
Enerly E, et al. (2011) miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors. PLoS ONE 6(2):e16915.
-
(2011)
PLoS ONE
, vol.6
, Issue.2
-
-
Enerly, E.1
-
26
-
-
84878968792
-
HMGA2 is an in vivo driver of tumor metastasis
-
in press
-
Morishita A, et al. (2013) HMGA2 is an in vivo driver of tumor metastasis. Cancer Res, in press.
-
(2013)
Cancer Res
-
-
Morishita, A.1
-
27
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu H, et al. (2011) Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473(7347):389-393.
-
(2011)
Nature
, vol.473
, Issue.7347
, pp. 389-393
-
-
Wu, H.1
-
28
-
-
79961125686
-
Tet1 and 5-hydroxymethylation: A genome-wide view in mouse embryonic stem cells
-
Wu H, Zhang Y (2011) Tet1 and 5-hydroxymethylation: A genome-wide view in mouse embryonic stem cells. Cell Cycle 10(15):2428-2436.
-
(2011)
Cell Cycle
, vol.10
, Issue.15
, pp. 2428-2436
-
-
Wu, H.1
Zhang, Y.2
-
29
-
-
80052933429
-
DNA demethylation dynamics
-
Bhutani N, Burns DM, Blau HM (2011) DNA demethylation dynamics. Cell 146(6):866-872.
-
(2011)
Cell
, vol.146
, Issue.6
, pp. 866-872
-
-
Bhutani, N.1
Burns, D.M.2
Blau, H.M.3
-
30
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S, et al. (2011) Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146(1):67-79.
-
(2011)
Cell
, vol.146
, Issue.1
, pp. 67-79
-
-
Cortellino, S.1
-
31
-
-
77951770118
-
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype
-
Gilbert PM, et al. (2010) HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. J Clin Invest 120(5):1535-1550.
-
(2010)
J Clin Invest
, vol.120
, Issue.5
, pp. 1535-1550
-
-
Gilbert, P.M.1
-
32
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang W, Sherman BT, Lempicki RA (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4(1):44-57.
-
(2009)
Nat Protoc
, vol.4
, Issue.1
, pp. 44-57
-
-
Huang, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
33
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
DOI 10.1073/pnas.0506580102
-
Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102(43):15545-15550. (Pubitemid 41528093)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
34
-
-
40749094918
-
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
-
DOI 10.1038/nature06781, PII NATURE06781
-
Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T (2008) SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 452(7184):187-193. (Pubitemid 351380252)
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 187-193
-
-
Han, H.-J.1
Russo, J.2
Kohwi, Y.3
Kohwi-Shigematsu, T.4
-
35
-
-
79955020072
-
Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2
-
Winter N, Nimzyk R, Bösche C, Meyer A, Bullerdiek J (2011) Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2. PLoS ONE 6(4):e18837.
-
(2011)
PLoS ONE
, vol.6
, Issue.4
-
-
Winter, N.1
Nimzyk, R.2
Bösche, C.3
Meyer, A.4
Bullerdiek, J.5
-
36
-
-
84866908544
-
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases
-
Hsu CH, et al. (2012) TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases. Cell Rep 2(3):568-579.
-
(2012)
Cell Rep
, vol.2
, Issue.3
, pp. 568-579
-
-
Hsu, C.H.1
-
37
-
-
0037099537
-
LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23)
-
Ono R, et al. (2002) LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res 62(14):4075-4080. (Pubitemid 34791077)
-
(2002)
Cancer Research
, vol.62
, Issue.14
, pp. 4075-4080
-
-
Ono, R.1
Taki, T.2
Taketani, T.3
Taniwaki, M.4
Kobayashi, H.5
Hayashi, Y.6
-
38
-
-
64049095814
-
HOXA9 is required for survival in human MLL-rearranged acute leukemias
-
Faber J, et al. (2009) HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood 113(11):2375-2385.
-
(2009)
Blood
, vol.113
, Issue.11
, pp. 2375-2385
-
-
Faber, J.1
-
39
-
-
33845319262
-
Epigenetic inactivation of the HOXA gene cluster in breast cancer
-
DOI 10.1158/0008-5472.CAN-06-2761
-
Novak P, et al. (2006) Epigenetic inactivation of the HOXA gene cluster in breast cancer. Cancer Res 66(22):10664-10670. (Pubitemid 44876960)
-
(2006)
Cancer Research
, vol.66
, Issue.22
, pp. 10664-10670
-
-
Novak, P.1
Jensen, T.2
Oshiro, M.M.3
Wozniak, R.J.4
Nouzova, M.5
Watts, G.S.6
Klimecki, W.T.7
Kim, C.8
Futscher, B.W.9
-
40
-
-
84859865967
-
The UCSC Genome Browser database: Extensions and updates 2011
-
Dreszer TR, et al. (2012) The UCSC Genome Browser database: Extensions and updates 2011. Nucleic Acids Res 40(Database issue):D918-D923.
-
(2012)
Nucleic Acids Res
, vol.40
, Issue.DATABASE ISSUE
-
-
Dreszer, T.R.1
|