Structural biology of glycoprotein hormones and their receptors: Insights to signaling

Molecular and Cellular Endocrinology

Volumn 382, Issue 1, 2014, Pages 424-451

  Jiang, Xuliang ^a   Dias, James A ^b   He, Xiaolin ^c  

^a EMD Serono Research Institute   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c NORTHWESTERN UNIVERSITY   (United States)

Author keywords

'Seat' sequence; Allosteric modulator; GPCR trimer; LRR curvature estimation; Receptor activation mechanism; Reproductive

Indexed keywords

CHORIONIC GONADOTROPIN; CYSTINE KNOT GROWTH FACTOR; FOLLITROPIN; FOLLITROPIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN; GLYCOPROTEIN HORMONE; GLYCOPROTEIN HORMONE RECEPTOR; GROWTH FACTOR; HORMONE RECEPTOR; PEPTIDE HORMONE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; DISULFIDE BOND; HORMONE BINDING; HUMAN; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SUBUNIT; RECEPTOR BINDING; REVIEW; SIGNAL TRANSDUCTION;

'SEAT' SEQUENCE; ALLOSTERIC MODULATOR; GPCR TRIMER; LRR CURVATURE ESTIMATION; RECEPTOR ACTIVATION MECHANISM; REPRODUCTIVE;

AMINO ACID SEQUENCE; ANIMALS; CRYSTALLOGRAPHY, X-RAY; FOLLICLE STIMULATING HORMONE; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; RECEPTORS, FSH; SIGNAL TRANSDUCTION;

EID: 84888287689     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.08.021     Document Type: Review

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