Allosteric communication between protomers of dopamine class a GPCR dimers modulates activation

Nature Chemical Biology

Volumn 5, Issue 9, 2009, Pages 688-695

  Han, Yang ^a,b   Moreira, Irina S ^c   Urizar, Eneko ^a,b   Weinstein, Harel ^c   Javitch, Jonathan A ^a,b  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; AEQUORIN; DIMER; DOPAMINE; DOPAMINE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HETERODIMER; QUINPIROLE;

ALLOSTERISM; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DRUG RECEPTOR BINDING; GENE ACTIVATION; GENETIC ENGINEERING; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; CELL LINE; COMPUTATIONAL BIOLOGY; GTP-BINDING PROTEINS; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROMOTER REGIONS, GENETIC; PROTEIN MULTIMERIZATION; QUINPIROLE; RECEPTORS, DOPAMINE D2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 69249158290     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.199     Document Type: Article

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