-
1
-
-
0032247323
-
The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies
-
Rapoport B., Chazenbalk G.D., Jaume J.C., et al. The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies. Endocr Rev 19 (1998) 673-716
-
(1998)
Endocr Rev
, vol.19
, pp. 673-716
-
-
Rapoport, B.1
Chazenbalk, G.D.2
Jaume, J.C.3
-
2
-
-
0025022499
-
Cloning, sequencing and expression of human TSH receptor
-
Misrahi M., Loosfelt H., Atger M., et al. Cloning, sequencing and expression of human TSH receptor. Biochem Biophys Res Commun 166 (1990) 394-403
-
(1990)
Biochem Biophys Res Commun
, vol.166
, pp. 394-403
-
-
Misrahi, M.1
Loosfelt, H.2
Atger, M.3
-
3
-
-
0024852495
-
Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor
-
Nagayama Y., Kaufman K.D., Seto P., et al. Molecular cloning, sequence and functional expression of the cDNA for the human thyrotropin receptor. Biochem Biophys Res Commun 165 (1989) 1184-1190
-
(1989)
Biochem Biophys Res Commun
, vol.165
, pp. 1184-1190
-
-
Nagayama, Y.1
Kaufman, K.D.2
Seto, P.3
-
4
-
-
0024826133
-
Molecular cloning of the thyrotropin receptor
-
Parmentier M., Libert F., Maenhaut C., et al. Molecular cloning of the thyrotropin receptor. Science 246 (1989) 1620-1622
-
(1989)
Science
, vol.246
, pp. 1620-1622
-
-
Parmentier, M.1
Libert, F.2
Maenhaut, C.3
-
5
-
-
4344647100
-
Minireview: thyrotropin receptor signaling in development and differentiation of the thyroid gland: insights from mouse models and human diseases
-
De Felice M., Postiglione M.P., and Di Lauro R. Minireview: thyrotropin receptor signaling in development and differentiation of the thyroid gland: insights from mouse models and human diseases. Endocrinology 145 (2004) 4062-4067
-
(2004)
Endocrinology
, vol.145
, pp. 4062-4067
-
-
De Felice, M.1
Postiglione, M.P.2
Di Lauro, R.3
-
6
-
-
0037180569
-
Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland
-
Postiglione M.P., Parlato R., Rodriguez-Mallon A., et al. Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland. Proc Natl Acad Sci U S A 99 (2002) 15462-15467
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15462-15467
-
-
Postiglione, M.P.1
Parlato, R.2
Rodriguez-Mallon, A.3
-
7
-
-
0037180426
-
Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice
-
Marians R.C., Ng L., Blair H.C., et al. Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice. Proc Natl Acad Sci U S A 99 (2002) 15776-15781
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 15776-15781
-
-
Marians, R.C.1
Ng, L.2
Blair, H.C.3
-
8
-
-
4344661206
-
Minireview: developmental regulation of thyrotropin receptor gene expression in the fetal and newborn thyroid
-
Brown R.S. Minireview: developmental regulation of thyrotropin receptor gene expression in the fetal and newborn thyroid. Endocrinology 145 (2004) 4058-4061
-
(2004)
Endocrinology
, vol.145
, pp. 4058-4061
-
-
Brown, R.S.1
-
10
-
-
23644456322
-
Thyrotropin receptor-associated diseases: from adenomata to Graves disease
-
Davies T.F., Ando T., Lin R.Y., et al. Thyrotropin receptor-associated diseases: from adenomata to Graves disease. J Clin Invest 115 (2005) 1972-1983
-
(2005)
J Clin Invest
, vol.115
, pp. 1972-1983
-
-
Davies, T.F.1
Ando, T.2
Lin, R.Y.3
-
11
-
-
41349100471
-
Thyroid stem cells: lessons from normal development and thyroid cancer
-
Thomas D., Friedman S., and Lin R.Y. Thyroid stem cells: lessons from normal development and thyroid cancer. Endocr Relat Cancer 15 (2008) 51-58
-
(2008)
Endocr Relat Cancer
, vol.15
, pp. 51-58
-
-
Thomas, D.1
Friedman, S.2
Lin, R.Y.3
-
12
-
-
0031764515
-
Thyrotropin receptor expression in Graves' orbital adipose/connective tissues: potential autoantigen in Graves' ophthalmopathy
-
Bahn R.S., Dutton C.M., Natt N., et al. Thyrotropin receptor expression in Graves' orbital adipose/connective tissues: potential autoantigen in Graves' ophthalmopathy. J Clin Endocrinol Metab 83 (1998) 998-1002
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 998-1002
-
-
Bahn, R.S.1
Dutton, C.M.2
Natt, N.3
-
14
-
-
0018638809
-
Lipolytic effect of TSH, glucagon and hydrocortisone on the adipose tissue of newborns and adults in vitro
-
Vizek K., Razova M., and Melichar V. Lipolytic effect of TSH, glucagon and hydrocortisone on the adipose tissue of newborns and adults in vitro. Physiol Bohemoslov 28 (1979) 325-331
-
(1979)
Physiol Bohemoslov
, vol.28
, pp. 325-331
-
-
Vizek, K.1
Razova, M.2
Melichar, V.3
-
15
-
-
0036161595
-
Evidence for thyrotropin receptor immunoreactivity in pretibial connective tissue from patients with thyroid-associated dermopathy
-
Daumerie C., Ludgate M., Costagliola S., et al. Evidence for thyrotropin receptor immunoreactivity in pretibial connective tissue from patients with thyroid-associated dermopathy. Eur J Endocrinol 146 (2002) 35-38
-
(2002)
Eur J Endocrinol
, vol.146
, pp. 35-38
-
-
Daumerie, C.1
Ludgate, M.2
Costagliola, S.3
-
16
-
-
38849185492
-
TSH stimulates adipogenesis in mouse embryonic stem cells
-
Lu M., and Lin R.Y. TSH stimulates adipogenesis in mouse embryonic stem cells. J Endocrinol 196 (2008) 159-169
-
(2008)
J Endocrinol
, vol.196
, pp. 159-169
-
-
Lu, M.1
Lin, R.Y.2
-
17
-
-
34248211130
-
Biological effects of thyrotropin receptor activation on human orbital preadipocytes
-
Zhang L., Baker G., Janus D., et al. Biological effects of thyrotropin receptor activation on human orbital preadipocytes. Invest Ophthalmol Vis Sci 47 (2006) 5197-5203
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 5197-5203
-
-
Zhang, L.1
Baker, G.2
Janus, D.3
-
18
-
-
37349006913
-
TNF-alpha and adipocyte biology
-
Cawthorn W.P., and Sethi J.K. TNF-alpha and adipocyte biology. FEBS Lett 582 (2008) 117-131
-
(2008)
FEBS Lett
, vol.582
, pp. 117-131
-
-
Cawthorn, W.P.1
Sethi, J.K.2
-
19
-
-
10744226715
-
TSH is a negative regulator of skeletal remodeling
-
Abe E., Marians R.C., Yu W., et al. TSH is a negative regulator of skeletal remodeling. Cell 115 (2003) 151-162
-
(2003)
Cell
, vol.115
, pp. 151-162
-
-
Abe, E.1
Marians, R.C.2
Yu, W.3
-
20
-
-
37249005803
-
Bone loss in thyroid disease: role of low TSH and high thyroid hormone
-
Abe E., Sun L., Mechanick J., et al. Bone loss in thyroid disease: role of low TSH and high thyroid hormone. Ann N Y Acad Sci 1116 (2007) 383-391
-
(2007)
Ann N Y Acad Sci
, vol.1116
, pp. 383-391
-
-
Abe, E.1
Sun, L.2
Mechanick, J.3
-
21
-
-
41949136377
-
Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss
-
Sun L., Vukicevic S., Baliram R., et al. Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A 105 (2008) 4289-4294
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 4289-4294
-
-
Sun, L.1
Vukicevic, S.2
Baliram, R.3
-
22
-
-
38749088288
-
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism
-
Bassett J.H., Williams A.J., Murphy E., et al. A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol Endocrinol 22 (2008) 501-512
-
(2008)
Mol Endocrinol
, vol.22
, pp. 501-512
-
-
Bassett, J.H.1
Williams, A.J.2
Murphy, E.3
-
23
-
-
0036514975
-
Autoimmune thyroid disease: new models of cell death in autoimmunity
-
Stassi G., and De M.R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol 2 (2002) 195-204
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 195-204
-
-
Stassi, G.1
De, M.R.2
-
24
-
-
0036895765
-
A monoclonal thyroid-stimulating antibody
-
Ando T., Latif R., Pritsker A., et al. A monoclonal thyroid-stimulating antibody. J Clin Invest 110 (2002) 1667-1674
-
(2002)
J Clin Invest
, vol.110
, pp. 1667-1674
-
-
Ando, T.1
Latif, R.2
Pritsker, A.3
-
25
-
-
0036921438
-
Generation of a mouse monoclonal TSH receptor antibody with stimulating activity
-
Costagliola S., Franssen J.D., Bonomi M., et al. Generation of a mouse monoclonal TSH receptor antibody with stimulating activity. Biochem Biophys Res Commun 299 (2002) 891-896
-
(2002)
Biochem Biophys Res Commun
, vol.299
, pp. 891-896
-
-
Costagliola, S.1
Franssen, J.D.2
Bonomi, M.3
-
26
-
-
12244265471
-
Thyroid-stimulating monoclonal antibodies
-
Sanders J., Jeffreys J., Depraetere H., et al. Thyroid-stimulating monoclonal antibodies. Thyroid 12 (2002) 1043-1050
-
(2002)
Thyroid
, vol.12
, pp. 1043-1050
-
-
Sanders, J.1
Jeffreys, J.2
Depraetere, H.3
-
27
-
-
85047692937
-
Concentration-dependent regulation of thyrotropin receptor function by thyroid-stimulating antibody
-
Ando T., Latif R., and Davies T.F. Concentration-dependent regulation of thyrotropin receptor function by thyroid-stimulating antibody. J Clin Invest 113 (2004) 1589-1595
-
(2004)
J Clin Invest
, vol.113
, pp. 1589-1595
-
-
Ando, T.1
Latif, R.2
Davies, T.F.3
-
28
-
-
0035976910
-
Oligomerization of the human thyrotropin receptor: fluorescent protein-tagged hTSHR reveals post-translational complexes
-
Latif R., Graves P., and Davies T.F. Oligomerization of the human thyrotropin receptor: fluorescent protein-tagged hTSHR reveals post-translational complexes. J Biol Chem 276 (2001) 45217-45224
-
(2001)
J Biol Chem
, vol.276
, pp. 45217-45224
-
-
Latif, R.1
Graves, P.2
Davies, T.F.3
-
29
-
-
0024806929
-
Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies
-
Libert F., Lefort A., Gerard C., et al. Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies. Biochem Biophys Res Commun 165 (1989) 1250-1255
-
(1989)
Biochem Biophys Res Commun
, vol.165
, pp. 1250-1255
-
-
Libert, F.1
Lefort, A.2
Gerard, C.3
-
30
-
-
0021797466
-
Analysis of thyrotropin receptors by photoaffinity labelling. Orientation of receptor subunits in the cell membrane
-
Kajita Y., Rickards C.R., Buckland P.R., et al. Analysis of thyrotropin receptors by photoaffinity labelling. Orientation of receptor subunits in the cell membrane. Biochem J 227 (1985) 413-420
-
(1985)
Biochem J
, vol.227
, pp. 413-420
-
-
Kajita, Y.1
Rickards, C.R.2
Buckland, P.R.3
-
31
-
-
0026605275
-
Two-subunit structure of the human thyrotropin receptor
-
Loosfelt H., Pichon C., Jolivet A., et al. Two-subunit structure of the human thyrotropin receptor. Proc Natl Acad Sci U S A 89 (1992) 3765-3769
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 3765-3769
-
-
Loosfelt, H.1
Pichon, C.2
Jolivet, A.3
-
32
-
-
0036214718
-
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist
-
Vlaeminck-Guillem V., Ho S.C., Rodien P., et al. Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. Mol Endocrinol 16 (2002) 736-746
-
(2002)
Mol Endocrinol
, vol.16
, pp. 736-746
-
-
Vlaeminck-Guillem, V.1
Ho, S.C.2
Rodien, P.3
-
33
-
-
17744366823
-
Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation
-
Neumann S., Claus M., and Paschke R. Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation. Eur J Endocrinol 152 (2005) 625-634
-
(2005)
Eur J Endocrinol
, vol.152
, pp. 625-634
-
-
Neumann, S.1
Claus, M.2
Paschke, R.3
-
34
-
-
27844482098
-
A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling
-
Claus M., Jaeschke H., Kleinau G., et al. A hydrophobic cluster in the center of the third extracellular loop is important for thyrotropin receptor signaling. Endocrinology 146 (2005) 5197-5203
-
(2005)
Endocrinology
, vol.146
, pp. 5197-5203
-
-
Claus, M.1
Jaeschke, H.2
Kleinau, G.3
-
35
-
-
12744280744
-
Structure of human follicle-stimulating hormone in complex with its receptor
-
Fan Q.R., and Hendrickson W.A. Structure of human follicle-stimulating hormone in complex with its receptor. Nature 433 (2005) 269-277
-
(2005)
Nature
, vol.433
, pp. 269-277
-
-
Fan, Q.R.1
Hendrickson, W.A.2
-
36
-
-
7244221618
-
Model of glycoprotein hormone receptor ligand binding and signaling
-
Moyle W.R., Xing Y., Lin W., et al. Model of glycoprotein hormone receptor ligand binding and signaling. J Biol Chem 279 (2004) 44442-44459
-
(2004)
J Biol Chem
, vol.279
, pp. 44442-44459
-
-
Moyle, W.R.1
Xing, Y.2
Lin, W.3
-
37
-
-
11344254774
-
Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling
-
Nunez M.R., Sanders J., Jeffreys J., et al. Analysis of the thyrotropin receptor-thyrotropin interaction by comparative modeling. Thyroid 14 (2004) 991-1011
-
(2004)
Thyroid
, vol.14
, pp. 991-1011
-
-
Nunez, M.R.1
Sanders, J.2
Jeffreys, J.3
-
38
-
-
43049109876
-
The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction
-
Mizutori Y., Chen C.R., McLachlan S.M., et al. The thyrotropin receptor hinge region is not simply a scaffold for the leucine-rich domain but contributes to ligand binding and signal transduction. Mol Endocrinol 22 5 (2008) 1171-1182
-
(2008)
Mol Endocrinol
, vol.22
, Issue.5
, pp. 1171-1182
-
-
Mizutori, Y.1
Chen, C.R.2
McLachlan, S.M.3
-
39
-
-
33750488472
-
Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor
-
Claus M., Neumann S., Kleinau G., et al. Structural determinants for G-protein activation and specificity in the third intracellular loop of the thyroid-stimulating hormone receptor. J Mol Med 84 (2006) 943-954
-
(2006)
J Mol Med
, vol.84
, pp. 943-954
-
-
Claus, M.1
Neumann, S.2
Kleinau, G.3
-
40
-
-
11144225829
-
Structural determinants for G protein activation and selectivity in the second intracellular loop of the thyrotropin receptor
-
Neumann S., Krause G., Claus M., et al. Structural determinants for G protein activation and selectivity in the second intracellular loop of the thyrotropin receptor. Endocrinology 146 (2005) 477-485
-
(2005)
Endocrinology
, vol.146
, pp. 477-485
-
-
Neumann, S.1
Krause, G.2
Claus, M.3
-
41
-
-
0025096140
-
An insertion in the human thyrotropin receptor critical for high affinity hormone binding
-
Wadsworth H.L., Chazenbalk G.D., Nagayama Y., et al. An insertion in the human thyrotropin receptor critical for high affinity hormone binding. Science 249 (1990) 1423-1425
-
(1990)
Science
, vol.249
, pp. 1423-1425
-
-
Wadsworth, H.L.1
Chazenbalk, G.D.2
Nagayama, Y.3
-
42
-
-
0025608144
-
Functional analysis of the cytoplasmic domains of the human thyrotropin receptor by site-directed mutagenesis
-
Chazenbalk G.D., Nagayama Y., Russo D., et al. Functional analysis of the cytoplasmic domains of the human thyrotropin receptor by site-directed mutagenesis. J Biol Chem 265 (1990) 20970-20975
-
(1990)
J Biol Chem
, vol.265
, pp. 20970-20975
-
-
Chazenbalk, G.D.1
Nagayama, Y.2
Russo, D.3
-
43
-
-
0026513428
-
Studies on the role of amino acids 38-45 in the expression of a functional thyrotropin receptor
-
Wadsworth H.L., Russo D., Nagayama Y., et al. Studies on the role of amino acids 38-45 in the expression of a functional thyrotropin receptor. Mol Endocrinol 6 (1992) 394-398
-
(1992)
Mol Endocrinol
, vol.6
, pp. 394-398
-
-
Wadsworth, H.L.1
Russo, D.2
Nagayama, Y.3
-
44
-
-
0034130131
-
New insights into the thyroid-stimulating hormone receptor. The major antigen of Graves' disease
-
vi
-
Graves P.N., and Davies T.F. New insights into the thyroid-stimulating hormone receptor. The major antigen of Graves' disease. Endocrinol Metab Clin North Am 29 (2000) 267-286 vi
-
(2000)
Endocrinol Metab Clin North Am
, vol.29
, pp. 267-286
-
-
Graves, P.N.1
Davies, T.F.2
-
45
-
-
0025743387
-
Eleven amino acids (Lys-201 to Lys-211) and 9 amino acids (Gly-222 to Leu-230) in the human thyrotropin receptor are involved in ligand binding
-
Nagayama Y., Russo D., Wadsworth H.L., et al. Eleven amino acids (Lys-201 to Lys-211) and 9 amino acids (Gly-222 to Leu-230) in the human thyrotropin receptor are involved in ligand binding. J Biol Chem 266 (1991) 14926-14930
-
(1991)
J Biol Chem
, vol.266
, pp. 14926-14930
-
-
Nagayama, Y.1
Russo, D.2
Wadsworth, H.L.3
-
46
-
-
0038182549
-
Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity
-
Smits G., Campillo M., Govaerts C., et al. Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity. EMBO J 22 (2003) 2692-2703
-
(2003)
EMBO J
, vol.22
, pp. 2692-2703
-
-
Smits, G.1
Campillo, M.2
Govaerts, C.3
-
47
-
-
0036963754
-
Characterization of the thyrotropin binding pocket
-
Jeffreys J., Depraetere H., Sanders J., et al. Characterization of the thyrotropin binding pocket. Thyroid 12 (2002) 1051-1061
-
(2002)
Thyroid
, vol.12
, pp. 1051-1061
-
-
Jeffreys, J.1
Depraetere, H.2
Sanders, J.3
-
48
-
-
0025831943
-
Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors
-
Nagayama Y., Wadsworth H.L., Russo D., et al. Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors. J Clin Invest 88 (1991) 336-340
-
(1991)
J Clin Invest
, vol.88
, pp. 336-340
-
-
Nagayama, Y.1
Wadsworth, H.L.2
Russo, D.3
-
49
-
-
35948937324
-
Molecular interactions between the TSH receptor and a thyroid-stimulating monoclonal autoantibody
-
Sanders J., Miguel R.N., Bolton J., et al. Molecular interactions between the TSH receptor and a thyroid-stimulating monoclonal autoantibody. Thyroid 17 (2007) 699-706
-
(2007)
Thyroid
, vol.17
, pp. 699-706
-
-
Sanders, J.1
Miguel, R.N.2
Bolton, J.3
-
50
-
-
34249941108
-
Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
-
Sanders J., Chirgadze D.Y., Sanders P., et al. Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody. Thyroid 17 (2007) 395-410
-
(2007)
Thyroid
, vol.17
, pp. 395-410
-
-
Sanders, J.1
Chirgadze, D.Y.2
Sanders, P.3
-
51
-
-
0037160035
-
Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor
-
Latif R., Graves P., and Davies T.F. Ligand-dependent inhibition of oligomerization at the human thyrotropin receptor. J Biol Chem 277 (2002) 45059-45067
-
(2002)
J Biol Chem
, vol.277
, pp. 45059-45067
-
-
Latif, R.1
Graves, P.2
Davies, T.F.3
-
52
-
-
35848969128
-
Antibody-induced modulation of TSH receptor post-translational processing
-
Ando T., Latif R., and Davies T.F. Antibody-induced modulation of TSH receptor post-translational processing. J Endocrinol 195 (2007) 179-186
-
(2007)
J Endocrinol
, vol.195
, pp. 179-186
-
-
Ando, T.1
Latif, R.2
Davies, T.F.3
-
53
-
-
34250753312
-
Modulation of TSHR signaling by posttranslational modifications
-
Kursawe R., and Paschke R. Modulation of TSHR signaling by posttranslational modifications. Trends Endocrinol Metab 18 (2007) 199-207
-
(2007)
Trends Endocrinol Metab
, vol.18
, pp. 199-207
-
-
Kursawe, R.1
Paschke, R.2
-
54
-
-
0028225588
-
Processing of the precursors of the human thyroid-stimulating hormone receptor in various eukaryotic cells (human thyrocytes, transfected L cells and baculovirus-infected insect cells)
-
Misrahi M., Ghinea N., Sar S., et al. Processing of the precursors of the human thyroid-stimulating hormone receptor in various eukaryotic cells (human thyrocytes, transfected L cells and baculovirus-infected insect cells). Eur J Biochem 222 (1994) 711-719
-
(1994)
Eur J Biochem
, vol.222
, pp. 711-719
-
-
Misrahi, M.1
Ghinea, N.2
Sar, S.3
-
55
-
-
0033607670
-
Subunit structure of thyrotropin receptors expressed on the cell surface
-
Tanaka K., Chazenbalk G.D., McLachlan S.M., et al. Subunit structure of thyrotropin receptors expressed on the cell surface. J Biol Chem 274 (1999) 33979-33984
-
(1999)
J Biol Chem
, vol.274
, pp. 33979-33984
-
-
Tanaka, K.1
Chazenbalk, G.D.2
McLachlan, S.M.3
-
56
-
-
0033803121
-
Identification of the sites of asparagine-linked glycosylation on the human thyrotropin receptor and studies on their role in receptor function and expression
-
Nagayama Y., Nishihara E., Namba H., et al. Identification of the sites of asparagine-linked glycosylation on the human thyrotropin receptor and studies on their role in receptor function and expression. J Pharmacol Exp Ther 295 (2000) 404-409
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 404-409
-
-
Nagayama, Y.1
Nishihara, E.2
Namba, H.3
-
57
-
-
0037084011
-
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors
-
Costagliola S., Panneels V., Bonomi M., et al. Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors. EMBO J 21 (2002) 504-513
-
(2002)
EMBO J
, vol.21
, pp. 504-513
-
-
Costagliola, S.1
Panneels, V.2
Bonomi, M.3
-
58
-
-
33751530407
-
Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues
-
Bonomi M., Busnelli M., Persani L., et al. Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues. Mol Endocrinol 20 (2006) 3351-3363
-
(2006)
Mol Endocrinol
, vol.20
, pp. 3351-3363
-
-
Bonomi, M.1
Busnelli, M.2
Persani, L.3
-
59
-
-
0029901387
-
Cysteine-699, a possible palmitoylation site of the thyrotropin receptor, is not crucial for cAMP or phosphoinositide signaling but is necessary for full surface expression
-
Kosugi S., and Mori T. Cysteine-699, a possible palmitoylation site of the thyrotropin receptor, is not crucial for cAMP or phosphoinositide signaling but is necessary for full surface expression. Biochem Biophys Res Commun 221 (1996) 636-640
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 636-640
-
-
Kosugi, S.1
Mori, T.2
-
61
-
-
0346059583
-
G protein-coupled receptor oligomerization: implications for G protein activation and cell signaling
-
Breitwieser G.E. G protein-coupled receptor oligomerization: implications for G protein activation and cell signaling. Circ Res 94 (2004) 17-27
-
(2004)
Circ Res
, vol.94
, pp. 17-27
-
-
Breitwieser, G.E.1
-
62
-
-
0029794790
-
Multimeric complex formation by the thyrotropin receptor in solubilized thyroid membranes
-
Graves P.N., Vlase H., Bobovnikova Y., et al. Multimeric complex formation by the thyrotropin receptor in solubilized thyroid membranes. Endocrinology 137 (1996) 3915-3920
-
(1996)
Endocrinology
, vol.137
, pp. 3915-3920
-
-
Graves, P.N.1
Vlase, H.2
Bobovnikova, Y.3
-
63
-
-
0028877877
-
Human autoantibodies to the thyrotropin receptor: recognition of linear, folded, and glycosylated recombinant extracellular domain
-
Vlase H., Graves P.N., Magnusson R.P., et al. Human autoantibodies to the thyrotropin receptor: recognition of linear, folded, and glycosylated recombinant extracellular domain. J Clin Endocrinol Metab 80 (1995) 46-53
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 46-53
-
-
Vlase, H.1
Graves, P.N.2
Magnusson, R.P.3
-
64
-
-
0026739764
-
Specific antibody to the thyrotropin receptor identifies multiple receptor forms in membranes of cells transfected with wild-type receptor complementary deoxyribonucleic acid: characterization of their relevance to receptor synthesis, processing, structure, and function
-
Ban T., Kosugi S., and Kohn L.D. Specific antibody to the thyrotropin receptor identifies multiple receptor forms in membranes of cells transfected with wild-type receptor complementary deoxyribonucleic acid: characterization of their relevance to receptor synthesis, processing, structure, and function. Endocrinology 131 (1992) 815-829
-
(1992)
Endocrinology
, vol.131
, pp. 815-829
-
-
Ban, T.1
Kosugi, S.2
Kohn, L.D.3
-
65
-
-
0029794790
-
Multimeric complex formation by the natural TSH receptor
-
Graves P.N., Vlase H., Bobovnikova Y., et al. Multimeric complex formation by the natural TSH receptor. Endocrinology 137 (1996) 3915-3920
-
(1996)
Endocrinology
, vol.137
, pp. 3915-3920
-
-
Graves, P.N.1
Vlase, H.2
Bobovnikova, Y.3
-
66
-
-
0029062431
-
Immunoprecipitation isolates multiple TSH receptor forms from human thyroid tissue
-
Grossman R.F., Ban T., Duh Q.Y., et al. Immunoprecipitation isolates multiple TSH receptor forms from human thyroid tissue. Thyroid 5 (1995) 101-105
-
(1995)
Thyroid
, vol.5
, pp. 101-105
-
-
Grossman, R.F.1
Ban, T.2
Duh, Q.Y.3
-
67
-
-
21244460359
-
Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity
-
Urizar E., Montanelli L., Loy T., et al. Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity. EMBO J 24 (2005) 1954-1964
-
(2005)
EMBO J
, vol.24
, pp. 1954-1964
-
-
Urizar, E.1
Montanelli, L.2
Loy, T.3
-
68
-
-
33846440512
-
Technology insight: modern methods to monitor protein-protein interactions reveal functional TSH receptor oligomerization
-
Persani L., Calebiro D., and Bonomi M. Technology insight: modern methods to monitor protein-protein interactions reveal functional TSH receptor oligomerization. Nat Clin Pract Endocrinol Metab 3 (2007) 180-190
-
(2007)
Nat Clin Pract Endocrinol Metab
, vol.3
, pp. 180-190
-
-
Persani, L.1
Calebiro, D.2
Bonomi, M.3
-
69
-
-
10844255797
-
Oligomerization of G protein-coupled receptors: past, present, and future
-
Park P.S., Filipek S., Wells J.W., et al. Oligomerization of G protein-coupled receptors: past, present, and future. Biochemistry 43 (2004) 15643-15656
-
(2004)
Biochemistry
, vol.43
, pp. 15643-15656
-
-
Park, P.S.1
Filipek, S.2
Wells, J.W.3
-
70
-
-
27544481186
-
Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance
-
Calebiro D., de F.T., Lucchi S., et al. Intracellular entrapment of wild-type TSH receptor by oligomerization with mutants linked to dominant TSH resistance. Hum Mol Genet 14 (2005) 2991-3002
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2991-3002
-
-
Calebiro, D.1
de, F.T.2
Lucchi, S.3
-
71
-
-
0242636871
-
Localization and regulation of thyrotropin receptors within lipid rafts
-
Latif R., Ando T., Daniel S., et al. Localization and regulation of thyrotropin receptors within lipid rafts. Endocrinology 144 (2003) 4725-4728
-
(2003)
Endocrinology
, vol.144
, pp. 4725-4728
-
-
Latif, R.1
Ando, T.2
Daniel, S.3
-
72
-
-
34347257788
-
Lipid rafts are triage centers for multimeric and monomeric thyrotropin receptor regulation
-
Latif R., Ando T., and Davies T.F. Lipid rafts are triage centers for multimeric and monomeric thyrotropin receptor regulation. Endocrinology 148 (2007) 3164-3175
-
(2007)
Endocrinology
, vol.148
, pp. 3164-3175
-
-
Latif, R.1
Ando, T.2
Davies, T.F.3
-
73
-
-
0030985241
-
Evidence that the TSH receptor ectodomain contains not one, but two, cleavage sites
-
Chazenbalk G.D., Tanaka K., Nagayama Y., et al. Evidence that the TSH receptor ectodomain contains not one, but two, cleavage sites. Endocrinology 138 (1997) 2893-2899
-
(1997)
Endocrinology
, vol.138
, pp. 2893-2899
-
-
Chazenbalk, G.D.1
Tanaka, K.2
Nagayama, Y.3
-
74
-
-
0031303386
-
Cleavage and shedding of the TSH receptor
-
Misrahi M., and Milgrom E. Cleavage and shedding of the TSH receptor. Eur J Endocrinol 137 (1997) 599-602
-
(1997)
Eur J Endocrinol
, vol.137
, pp. 599-602
-
-
Misrahi, M.1
Milgrom, E.2
-
75
-
-
0030053238
-
Shedding of human TSH receptor ectodomain: involvement of a matrix metalloprotease
-
Couet J., Sar S., Jolivet A., et al. Shedding of human TSH receptor ectodomain: involvement of a matrix metalloprotease. J Biol Chem 271 (1996) 4545-4552
-
(1996)
J Biol Chem
, vol.271
, pp. 4545-4552
-
-
Couet, J.1
Sar, S.2
Jolivet, A.3
-
76
-
-
0032898172
-
Sequential cleavage and excision of a segment of the thyrotropin receptor ectodomain
-
de Bernard S., Misrahi M., Huet J.C., et al. Sequential cleavage and excision of a segment of the thyrotropin receptor ectodomain. J Biol Chem 274 (1999) 101-107
-
(1999)
J Biol Chem
, vol.274
, pp. 101-107
-
-
de Bernard, S.1
Misrahi, M.2
Huet, J.C.3
-
77
-
-
37549003693
-
Cleavage of the human thyrotropin receptor by ADAM10 is regulated by thyrotropin
-
Kaczur V., Puskas L.G., Nagy Z.U., et al. Cleavage of the human thyrotropin receptor by ADAM10 is regulated by thyrotropin. J Mol Recognit 20 (2007) 392-404
-
(2007)
J Mol Recognit
, vol.20
, pp. 392-404
-
-
Kaczur, V.1
Puskas, L.G.2
Nagy, Z.U.3
-
78
-
-
0030471654
-
Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain
-
Couet J., de Bernard S., Loosfelt H., et al. Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain. Biochemistry 35 (1996) 14800-14805
-
(1996)
Biochemistry
, vol.35
, pp. 14800-14805
-
-
Couet, J.1
de Bernard, S.2
Loosfelt, H.3
-
79
-
-
0030053238
-
Shedding of human thyrotropin receptor ectodomain Involvement of a matrix metalloprotease
-
Couet J., Sar S., Jolivet A., et al. Shedding of human thyrotropin receptor ectodomain Involvement of a matrix metalloprotease. J Biol Chem 271 8 (1996) 4545-4552
-
(1996)
J Biol Chem
, vol.271
, Issue.8
, pp. 4545-4552
-
-
Couet, J.1
Sar, S.2
Jolivet, A.3
-
80
-
-
33646775993
-
Evidence that human thyroid cells express uncleaved, single-chain thyrotropin receptors on their surface
-
Chen C.R., Chazenbalk G.D., Wawrowsky K.A., et al. Evidence that human thyroid cells express uncleaved, single-chain thyrotropin receptors on their surface. Endocrinology 147 (2006) 3107-3113
-
(2006)
Endocrinology
, vol.147
, pp. 3107-3113
-
-
Chen, C.R.1
Chazenbalk, G.D.2
Wawrowsky, K.A.3
-
81
-
-
9444277288
-
Monomerization as a prerequisite for intramolecular cleavage and shedding of the thyrotropin receptor
-
Latif R., Ando T., and Davies T.F. Monomerization as a prerequisite for intramolecular cleavage and shedding of the thyrotropin receptor. Endocrinology 145 (2004) 5580-5588
-
(2004)
Endocrinology
, vol.145
, pp. 5580-5588
-
-
Latif, R.1
Ando, T.2
Davies, T.F.3
-
82
-
-
0347719554
-
A physiological role for the posttranslational cleavage of the thyrotropin receptor?
-
Vassart G., and Costagliola S. A physiological role for the posttranslational cleavage of the thyrotropin receptor?. Endocrinology 145 (2004) 1-3
-
(2004)
Endocrinology
, vol.145
, pp. 1-3
-
-
Vassart, G.1
Costagliola, S.2
-
83
-
-
0037634641
-
Functional assessment of the thyrotropin receptor-beta subunit
-
Ciullo I., Latif R., Graves P., et al. Functional assessment of the thyrotropin receptor-beta subunit. Endocrinology 144 (2003) 3176-3181
-
(2003)
Endocrinology
, vol.144
, pp. 3176-3181
-
-
Ciullo, I.1
Latif, R.2
Graves, P.3
-
84
-
-
0042324612
-
Role of cleavage and shedding in human thyrotropin receptor function and trafficking
-
Quellari M., Desroches A., Beau I., et al. Role of cleavage and shedding in human thyrotropin receptor function and trafficking. Eur J Biochem 270 (2003) 3486-3497
-
(2003)
Eur J Biochem
, vol.270
, pp. 3486-3497
-
-
Quellari, M.1
Desroches, A.2
Beau, I.3
-
85
-
-
0028224772
-
The human thyrotropin receptor activates G-proteins Gs and Gq/11
-
Allgeier A., Offermanns S., Van Sande J., et al. The human thyrotropin receptor activates G-proteins Gs and Gq/11. J Biol Chem 269 (1994) 13733-13735
-
(1994)
J Biol Chem
, vol.269
, pp. 13733-13735
-
-
Allgeier, A.1
Offermanns, S.2
Van Sande, J.3
-
86
-
-
0034793849
-
Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models
-
Kimura T., Van K.A., Golstein J., et al. Regulation of thyroid cell proliferation by TSH and other factors: a critical evaluation of in vitro models. Endocr Rev 22 (2001) 631-656
-
(2001)
Endocr Rev
, vol.22
, pp. 631-656
-
-
Kimura, T.1
Van, K.A.2
Golstein, J.3
-
87
-
-
0029888302
-
Specific activation of the thyrotropin receptor by trypsin
-
Van S.J., Massart C., Costagliola S., et al. Specific activation of the thyrotropin receptor by trypsin. Mol Cell Endocrinol 119 (1996) 161-168
-
(1996)
Mol Cell Endocrinol
, vol.119
, pp. 161-168
-
-
Van, S.J.1
Massart, C.2
Costagliola, S.3
-
88
-
-
1542316313
-
A molecular dissection of the glycoprotein hormone receptors
-
Vassart G., Pardo L., and Costagliola S. A molecular dissection of the glycoprotein hormone receptors. Trends Biochem Sci 29 (2004) 119-126
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 119-126
-
-
Vassart, G.1
Pardo, L.2
Costagliola, S.3
-
89
-
-
0036083401
-
Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships
-
Szkudlinski M.W., Fremont V., Ronin C., et al. Thyroid-stimulating hormone and thyroid-stimulating hormone receptor structure-function relationships. Physiol Rev 82 (2002) 473-502
-
(2002)
Physiol Rev
, vol.82
, pp. 473-502
-
-
Szkudlinski, M.W.1
Fremont, V.2
Ronin, C.3
-
90
-
-
0034457935
-
The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design
-
Zhang M., Tong K.P., Fremont V., et al. The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone-receptor interaction and antagonist design. Endocrinology 141 (2000) 3514-3517
-
(2000)
Endocrinology
, vol.141
, pp. 3514-3517
-
-
Zhang, M.1
Tong, K.P.2
Fremont, V.3
-
91
-
-
0028152333
-
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
-
Marshall C.J. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. Curr Opin Genet Dev 4 (1994) 82-89
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 82-89
-
-
Marshall, C.J.1
-
92
-
-
34748905609
-
Cyclic AMP-dependent protein kinases, but not Epac, mediate TSH/cyclic AMP-dependent regulation of thyroid cells
-
Dremier S., Milenkovic M., Blancquaert S., et al. Cyclic AMP-dependent protein kinases, but not Epac, mediate TSH/cyclic AMP-dependent regulation of thyroid cells. Endocrinology 148 10 (2007) 4612-4622
-
(2007)
Endocrinology
, vol.148
, Issue.10
, pp. 4612-4622
-
-
Dremier, S.1
Milenkovic, M.2
Blancquaert, S.3
-
93
-
-
0040175067
-
Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction
-
Frodin M., and Gammeltoft S. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction. Mol Cell Endocrinol 151 (1999) 65-77
-
(1999)
Mol Cell Endocrinol
, vol.151
, pp. 65-77
-
-
Frodin, M.1
Gammeltoft, S.2
-
94
-
-
0029090212
-
Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase
-
Stoyanov B., Volinia S., Hanck T., et al. Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase. Science 269 (1995) 690-693
-
(1995)
Science
, vol.269
, pp. 690-693
-
-
Stoyanov, B.1
Volinia, S.2
Hanck, T.3
-
95
-
-
1542290670
-
Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins
-
Kasri N.N., Holmes A.M., Bultynck G., et al. Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins. EMBO J 23 (2004) 312-321
-
(2004)
EMBO J
, vol.23
, pp. 312-321
-
-
Kasri, N.N.1
Holmes, A.M.2
Bultynck, G.3
-
96
-
-
0034644523
-
Cellular signaling: pivoting around PDK-1
-
Toker A., and Newton A.C. Cellular signaling: pivoting around PDK-1. Cell 103 (2000) 185-188
-
(2000)
Cell
, vol.103
, pp. 185-188
-
-
Toker, A.1
Newton, A.C.2
-
97
-
-
0034634443
-
Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms
-
Balendran A., Hare G.R., Kieloch A., et al. Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms. FEBS Lett 484 (2000) 217-223
-
(2000)
FEBS Lett
, vol.484
, pp. 217-223
-
-
Balendran, A.1
Hare, G.R.2
Kieloch, A.3
-
98
-
-
0032053709
-
Mechanisms and consequences of activation of protein kinase B/Akt
-
Downward J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr Opin Cell Biol 10 (1998) 262-267
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 262-267
-
-
Downward, J.1
-
99
-
-
0032480885
-
Signal transduction. New exchange, new target
-
Downward J. Signal transduction. New exchange, new target. Nature 396 (1998) 416-417
-
(1998)
Nature
, vol.396
, pp. 416-417
-
-
Downward, J.1
-
100
-
-
0034176579
-
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
-
Williams M.R., Arthur J.S., Balendran A., et al. The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr Biol 10 (2000) 439-448
-
(2000)
Curr Biol
, vol.10
, pp. 439-448
-
-
Williams, M.R.1
Arthur, J.S.2
Balendran, A.3
-
101
-
-
43049137345
-
G{beta}{gamma} dimers released in response to TSH activate phosphoinositide 3-kinase and regulate gene expression in thyroid cells
-
Zaballos M.A., Garcia B., and Santisteban P. G{beta}{gamma} dimers released in response to TSH activate phosphoinositide 3-kinase and regulate gene expression in thyroid cells. Mol Endocrinol 22 5 (2008) 1183-1199
-
(2008)
Mol Endocrinol
, vol.22
, Issue.5
, pp. 1183-1199
-
-
Zaballos, M.A.1
Garcia, B.2
Santisteban, P.3
-
102
-
-
15444374341
-
Requirement of thyrotropin-dependent complex formation of protein kinase A catalytic subunit with inhibitor of {kappa}B proteins for activation of p65 nuclear factor-{kappa}B by tumor necrosis factor-{alpha}
-
Cao X., Kambe F., and Seo H. Requirement of thyrotropin-dependent complex formation of protein kinase A catalytic subunit with inhibitor of {kappa}B proteins for activation of p65 nuclear factor-{kappa}B by tumor necrosis factor-{alpha}. Endocrinology 146 (2005) 1999-2005
-
(2005)
Endocrinology
, vol.146
, pp. 1999-2005
-
-
Cao, X.1
Kambe, F.2
Seo, H.3
-
103
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle P.A., and Henkel T. Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12 (1994) 141-179
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
104
-
-
0034753081
-
Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism
-
Iacovelli L., Capobianco L., Salvatore L., et al. Thyrotropin activates mitogen-activated protein kinase pathway in FRTL-5 by a cAMP-dependent protein kinase A-independent mechanism. Mol Pharmacol 60 (2001) 924-933
-
(2001)
Mol Pharmacol
, vol.60
, pp. 924-933
-
-
Iacovelli, L.1
Capobianco, L.2
Salvatore, L.3
-
105
-
-
0037200679
-
Involvement of the protein kinase C pathway in thyrotropin-induced STAT3 activation in FRTL-5 thyroid cells
-
Park Y.J., Park E.S., Kim M.S., et al. Involvement of the protein kinase C pathway in thyrotropin-induced STAT3 activation in FRTL-5 thyroid cells. Mol Cell Endocrinol 194 (2002) 77-84
-
(2002)
Mol Cell Endocrinol
, vol.194
, pp. 77-84
-
-
Park, Y.J.1
Park, E.S.2
Kim, M.S.3
-
106
-
-
0034644525
-
TOR, a central controller of cell growth
-
Schmelzle T., and Hall M.N. TOR, a central controller of cell growth. Cell 103 (2000) 253-262
-
(2000)
Cell
, vol.103
, pp. 253-262
-
-
Schmelzle, T.1
Hall, M.N.2
-
107
-
-
34548580330
-
Thyroid-stimulating hormone initiated proliferative signals converge in vivo on the mTOR kinase without activating AKT
-
Brewer C., Yeager N., and Di C.A. Thyroid-stimulating hormone initiated proliferative signals converge in vivo on the mTOR kinase without activating AKT. Cancer Res 67 (2007) 8002-8006
-
(2007)
Cancer Res
, vol.67
, pp. 8002-8006
-
-
Brewer, C.1
Yeager, N.2
Di, C.A.3
-
108
-
-
0141801751
-
Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function
-
Tomer Y., and Davies T.F. Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function. Endocr Rev 24 (2003) 694-717
-
(2003)
Endocr Rev
, vol.24
, pp. 694-717
-
-
Tomer, Y.1
Davies, T.F.2
-
110
-
-
13844271908
-
Thyrotropin receptor antibodies: new insights into their actions and clinical relevance
-
Ando T., Latif R., and Davies T.F. Thyrotropin receptor antibodies: new insights into their actions and clinical relevance. Best Pract Res Clin Endocrinol Metab 19 (2005) 33-52
-
(2005)
Best Pract Res Clin Endocrinol Metab
, vol.19
, pp. 33-52
-
-
Ando, T.1
Latif, R.2
Davies, T.F.3
-
111
-
-
0033849505
-
The prevalence and clinical significance of blocking thyrotropin receptor antibodies in untreated hyperthyroid Graves' disease
-
Kim W.B., Chung H.K., Park Y.J., et al. The prevalence and clinical significance of blocking thyrotropin receptor antibodies in untreated hyperthyroid Graves' disease. Thyroid 10 (2000) 579-586
-
(2000)
Thyroid
, vol.10
, pp. 579-586
-
-
Kim, W.B.1
Chung, H.K.2
Park, Y.J.3
-
112
-
-
0033231269
-
Autoantibodies interacting with purified native thyrotropin receptor
-
Atger M., Misrahi M., Young J., et al. Autoantibodies interacting with purified native thyrotropin receptor. Eur J Biochem 265 (1999) 1022-1031
-
(1999)
Eur J Biochem
, vol.265
, pp. 1022-1031
-
-
Atger, M.1
Misrahi, M.2
Young, J.3
-
113
-
-
0025184265
-
Thyroid-stimulating antibody activity between different immunoglobulin G subclasses
-
Weetman A.P., Yateman M.E., Ealey P.A., et al. Thyroid-stimulating antibody activity between different immunoglobulin G subclasses. J Clin Invest 86 (1990) 723-727
-
(1990)
J Clin Invest
, vol.86
, pp. 723-727
-
-
Weetman, A.P.1
Yateman, M.E.2
Ealey, P.A.3
-
114
-
-
0020659825
-
Immunochemical characterization of the thyroid-stimulating antibody (TSAb) of Graves' disease: evidence for restricted heterogeneity
-
Zakarija M. Immunochemical characterization of the thyroid-stimulating antibody (TSAb) of Graves' disease: evidence for restricted heterogeneity. J Clin Lab Immunol 10 (1983) 77-85
-
(1983)
J Clin Lab Immunol
, vol.10
, pp. 77-85
-
-
Zakarija, M.1
-
115
-
-
0036284405
-
Demonstration of immunoglobulin G, A, and E autoantibodies to the human thyrotropin receptor using flow cytometry
-
Metcalfe R., Jordan N., Watson P., et al. Demonstration of immunoglobulin G, A, and E autoantibodies to the human thyrotropin receptor using flow cytometry. J Clin Endocrinol Metab 87 (2002) 1754-1761
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1754-1761
-
-
Metcalfe, R.1
Jordan, N.2
Watson, P.3
-
116
-
-
0037967531
-
Human monoclonal thyroid stimulating autoantibody
-
Sanders J., Evans M., Premawardhana L.D., et al. Human monoclonal thyroid stimulating autoantibody. Lancet 362 (2003) 126-128
-
(2003)
Lancet
, vol.362
, pp. 126-128
-
-
Sanders, J.1
Evans, M.2
Premawardhana, L.D.3
-
118
-
-
9644295678
-
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity
-
Costagliola S., Bonomi M., Morgenthaler N.G., et al. Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol 18 (2004) 3020-3034
-
(2004)
Mol Endocrinol
, vol.18
, pp. 3020-3034
-
-
Costagliola, S.1
Bonomi, M.2
Morgenthaler, N.G.3
-
119
-
-
1842611681
-
Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor
-
Minich W.B., Lenzner C., and Morgenthaler N.G. Antibodies to TSH-receptor in thyroid autoimmune disease interact with monoclonal antibodies whose epitopes are broadly distributed on the receptor. Clin Exp Immunol 136 (2004) 129-136
-
(2004)
Clin Exp Immunol
, vol.136
, pp. 129-136
-
-
Minich, W.B.1
Lenzner, C.2
Morgenthaler, N.G.3
-
120
-
-
0037322469
-
Induction of thyroid-stimulating hormone receptor autoimmunity in hamsters
-
Ando T., Imaizumi M., Graves P., et al. Induction of thyroid-stimulating hormone receptor autoimmunity in hamsters. Endocrinology 144 (2003) 671-680
-
(2003)
Endocrinology
, vol.144
, pp. 671-680
-
-
Ando, T.1
Imaizumi, M.2
Graves, P.3
-
121
-
-
9244245203
-
Dissecting linear and conformational epitopes on the native thyrotropin receptor
-
Ando T., Latif R., Daniel S., et al. Dissecting linear and conformational epitopes on the native thyrotropin receptor. Endocrinology 145 (2004) 5185-5193
-
(2004)
Endocrinology
, vol.145
, pp. 5185-5193
-
-
Ando, T.1
Latif, R.2
Daniel, S.3
-
122
-
-
0037087373
-
A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor
-
Nagayama Y., Kita-Furuyama M., Ando T., et al. A novel murine model of Graves' hyperthyroidism with intramuscular injection of adenovirus expressing the thyrotropin receptor. J Immunol 168 (2002) 2789-2794
-
(2002)
J Immunol
, vol.168
, pp. 2789-2794
-
-
Nagayama, Y.1
Kita-Furuyama, M.2
Ando, T.3
-
123
-
-
0038410113
-
The cysteine-rich amino terminus of the thyrotropin receptor is the immunodominant linear antibody epitope in mice immunized using naked deoxyribonucleic acid or adenovirus vectors
-
Schwarz-Lauer L., Pichurin P.N., Chen C.R., et al. The cysteine-rich amino terminus of the thyrotropin receptor is the immunodominant linear antibody epitope in mice immunized using naked deoxyribonucleic acid or adenovirus vectors. Endocrinology 144 (2003) 1718-1725
-
(2003)
Endocrinology
, vol.144
, pp. 1718-1725
-
-
Schwarz-Lauer, L.1
Pichurin, P.N.2
Chen, C.R.3
-
124
-
-
58149471219
-
Characterization of thyrotropin receptor antibody-induced signaling cascades
-
Morshed S.A., Latif R., and Davies T.F. Characterization of thyrotropin receptor antibody-induced signaling cascades. Endocrinology 150 1 (2009) 519-529
-
(2009)
Endocrinology
, vol.150
, Issue.1
, pp. 519-529
-
-
Morshed, S.A.1
Latif, R.2
Davies, T.F.3
-
125
-
-
33645759708
-
Monoclonal pathogenic antibodies to the thyroid-stimulating hormone receptor in Graves' disease with potent thyroid-stimulating activity but differential blocking activity activate multiple signaling pathways
-
Gilbert J.A., Gianoukakis A.G., Salehi S., et al. Monoclonal pathogenic antibodies to the thyroid-stimulating hormone receptor in Graves' disease with potent thyroid-stimulating activity but differential blocking activity activate multiple signaling pathways. J Immunol 176 (2006) 5084-5092
-
(2006)
J Immunol
, vol.176
, pp. 5084-5092
-
-
Gilbert, J.A.1
Gianoukakis, A.G.2
Salehi, S.3
-
126
-
-
24744466316
-
Monoclonal antibodies to the thyrotropin receptor
-
Ando T., and Davies T.F. Monoclonal antibodies to the thyrotropin receptor. Clin Dev Immunol 12 (2005) 137-143
-
(2005)
Clin Dev Immunol
, vol.12
, pp. 137-143
-
-
Ando, T.1
Davies, T.F.2
-
127
-
-
0031939694
-
Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor
-
Costagliola S., Rodien P., Many M.C., et al. Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor. J Immunol 160 (1998) 1458-1465
-
(1998)
J Immunol
, vol.160
, pp. 1458-1465
-
-
Costagliola, S.1
Rodien, P.2
Many, M.C.3
-
128
-
-
34249789301
-
Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activity
-
Chen C.R., McLachlan S.M., and Rapoport B. Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activity. Endocrinology 148 (2007) 2375-2382
-
(2007)
Endocrinology
, vol.148
, pp. 2375-2382
-
-
Chen, C.R.1
McLachlan, S.M.2
Rapoport, B.3
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