Substitution of the seat-belt region of the thyroid-stimulating hormone (TSH) β-subunit with the corresponding regions of choriogonadotropin or follitropin confers luteotropic but not follitropic activity to chimeric TSH

Journal of Biological Chemistry

Volumn 272, Issue 24, 1997, Pages 15532-15540

  Grossmann, Mathis ^a,e   Szkudlinski, Mariusz W ^a   Wong, Rosemary ^b   Dias, James A ^c   Ji, Tae H ^d   Weintraub, Bruce D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c WADSWORTH CENTER   (United States)

^d UNIVERSITY OF WYOMING   (United States)

^e INSTITUTE OF HUMAN VIROLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN; FOLLITROPIN; FOLLITROPIN RECEPTOR; GLYCOPROTEIN; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; PROTEIN SUBUNIT; THYROTROPIN; THYROTROPIN RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; HORMONE ACTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RECEPTOR AFFINITY; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; CHO CELLS; CHORIONIC GONADOTROPIN; CRICETINAE; FOLLICLE STIMULATING HORMONE; HUMANS; LUTEINIZING HORMONE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT FUSION PROTEINS; THYROTROPIN;

EID: 0030969880     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.24.15532     Document Type: Article

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